Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_007_A24 (250 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O44441|ATIF2_CAEEL Probable ATPase inhibitor B0546.1, mi... 65 4e-11 sp|Q03344|ATIF1_RAT ATPase inhibitor, mitochondrial precursor 64 1e-10 sp|O35143|ATIF1_MOUSE ATPase inhibitor, mitochondrial precu... 62 5e-10 sp|P01096|ATIF1_BOVIN ATPase inhibitor, mitochondrial precu... 59 3e-09 sp|Q9UII2|ATIF1_HUMAN ATPase inhibitor, mitochondrial precu... 59 5e-09 sp|Q29307|ATIF1_PIG ATPase inhibitor, mitochondrial precursor 55 5e-08 sp|P37209|ATIF1_CAEEL ATPase inhibitor, mitochondrial homolog 50 2e-06 sp|Q40554|IF3A_TOBAC Eukaryotic translation initiation fact... 28 5.0 sp|O75116|ROCK2_HUMAN Rho-associated protein kinase 2 (Rho-... 28 5.0 sp|Q28021|ROCK2_BOVIN Rho-associated protein kinase 2 (Rho-... 28 6.5
>sp|O44441|ATIF2_CAEEL Probable ATPase inhibitor B0546.1, mitochondrial precursor Length = 109 Score = 65.5 bits (158), Expect = 4e-11 Identities = 26/57 (45%), Positives = 43/57 (75%) Frame = +2 Query: 80 TIRDAGGSFGKKEAYLEEEYFRKLNNRQIKELKDHLEDEIDTHTHEIEKHEEAVKRH 250 +IRDAGG+FGK EA E+EYF K Q++EL++H+++E+ H ++E H++ ++RH Sbjct: 36 SIRDAGGAFGKMEAAREDEYFYKKQKAQLQELREHIQEEVKHHEGQLENHKKVLERH 92
>sp|Q03344|ATIF1_RAT ATPase inhibitor, mitochondrial precursor Length = 107 Score = 63.5 bits (153), Expect = 1e-10 Identities = 28/57 (49%), Positives = 41/57 (71%) Frame = +2 Query: 80 TIRDAGGSFGKKEAYLEEEYFRKLNNRQIKELKDHLEDEIDTHTHEIEKHEEAVKRH 250 +IR+AGG+FGK+E E+ YFR+ Q+ LK H EDEID H+ EIE+ ++ ++RH Sbjct: 39 SIREAGGAFGKREKAEEDRYFREKTREQLAALKKHHEDEIDHHSKEIERLQKQIERH 95
>sp|O35143|ATIF1_MOUSE ATPase inhibitor, mitochondrial precursor Length = 106 Score = 61.6 bits (148), Expect = 5e-10 Identities = 27/57 (47%), Positives = 40/57 (70%) Frame = +2 Query: 80 TIRDAGGSFGKKEAYLEEEYFRKLNNRQIKELKDHLEDEIDTHTHEIEKHEEAVKRH 250 +IR+AGG+FGK+E E+ YFR+ Q+ L+ H EDEID H+ EIE+ ++ + RH Sbjct: 39 SIREAGGAFGKREKAEEDRYFREKTKEQLAALRKHHEDEIDHHSKEIERLQKQIDRH 95
>sp|P01096|ATIF1_BOVIN ATPase inhibitor, mitochondrial precursor Length = 109 Score = 59.3 bits (142), Expect = 3e-09 Identities = 27/56 (48%), Positives = 37/56 (66%) Frame = +2 Query: 83 IRDAGGSFGKKEAYLEEEYFRKLNNRQIKELKDHLEDEIDTHTHEIEKHEEAVKRH 250 +RDAGG+FGK+E EE YFR Q+ LK H E+EI H EIE+ ++ ++RH Sbjct: 40 VRDAGGAFGKREQAEEERYFRARAKEQLAALKKHHENEISHHAKEIERLQKEIERH 95
>sp|Q9UII2|ATIF1_HUMAN ATPase inhibitor, mitochondrial precursor sp|Q5RFJ9|ATIF1_PONPY ATPase inhibitor, mitochondrial precursor Length = 106 Score = 58.5 bits (140), Expect = 5e-09 Identities = 27/57 (47%), Positives = 39/57 (68%) Frame = +2 Query: 80 TIRDAGGSFGKKEAYLEEEYFRKLNNRQIKELKDHLEDEIDTHTHEIEKHEEAVKRH 250 +IR+AGG+FGK+E EE YFR + Q+ LK H E+EI H EIE+ ++ ++RH Sbjct: 39 SIREAGGAFGKREQAEEERYFRAQSREQLAALKKHHEEEIVHHKKEIERLQKEIERH 95
>sp|Q29307|ATIF1_PIG ATPase inhibitor, mitochondrial precursor Length = 108 Score = 55.1 bits (131), Expect = 5e-08 Identities = 26/56 (46%), Positives = 35/56 (62%) Frame = +2 Query: 83 IRDAGGSFGKKEAYLEEEYFRKLNNRQIKELKDHLEDEIDTHTHEIEKHEEAVKRH 250 +R AGG+FGKKE EE YFR Q+ LK H E+ I H EIE+ ++ ++RH Sbjct: 40 VRXAGGAFGKKEQADEERYFRARAREQLAALKKHHENXISHHVKEIERLQKEIERH 95
>sp|P37209|ATIF1_CAEEL ATPase inhibitor, mitochondrial homolog Length = 88 Score = 49.7 bits (117), Expect = 2e-06 Identities = 24/57 (42%), Positives = 34/57 (59%) Frame = +2 Query: 80 TIRDAGGSFGKKEAYLEEEYFRKLNNRQIKELKDHLEDEIDTHTHEIEKHEEAVKRH 250 +IR+AGGS G A EEEYFR+ Q+ LK LE ++ EI HE+ +++H Sbjct: 19 SIREAGGSLGMMGATREEEYFRRQQKDQLDNLKKKLEADMTQSQQEIRDHEKVLEQH 75
>sp|Q40554|IF3A_TOBAC Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (Eukaryotic translation initiation factor 3 large subunit) (eIF3a) (PNLA-35) Length = 958 Score = 28.5 bits (62), Expect = 5.0 Identities = 13/38 (34%), Positives = 21/38 (55%) Frame = +2 Query: 134 EYFRKLNNRQIKELKDHLEDEIDTHTHEIEKHEEAVKR 247 EY ++ N R +KE++D +E HE EK + K+ Sbjct: 611 EYEQRRNQRILKEIEDRELEEAQALLHEAEKRSKRKKK 648
>sp|O75116|ROCK2_HUMAN Rho-associated protein kinase 2 (Rho-associated, coiled-coil containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2) Length = 1388 Score = 28.5 bits (62), Expect = 5.0 Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 1/51 (1%) Frame = +2 Query: 86 RDAGGSFGKKEAYLE-EEYFRKLNNRQIKELKDHLEDEIDTHTHEIEKHEE 235 +DA G + + LE E+YF L Q++ELK+ E++ +K +E Sbjct: 853 QDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQE 903
>sp|Q28021|ROCK2_BOVIN Rho-associated protein kinase 2 (Rho-associated, coiled-coil containing protein kinase 2) (p164 ROCK-2) Length = 1388 Score = 28.1 bits (61), Expect = 6.5 Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 1/38 (2%) Frame = +2 Query: 86 RDAGGSFGKKEAYLE-EEYFRKLNNRQIKELKDHLEDE 196 +DA G + + LE E+YF L Q++ELK+ E++ Sbjct: 853 QDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEK 890
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,698,196 Number of Sequences: 369166 Number of extensions: 229029 Number of successful extensions: 1281 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1238 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1278 length of database: 68,354,980 effective HSP length: 53 effective length of database: 58,564,025 effective search space used: 1698356725 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)