Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_A17
(761 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q18223|FBSP1_CAEEL F-box/SPRY-domain protein 1 (F-box sy... 91 4e-18
sp|Q9V6L9|FBSP1_DROME F-box/SPRY-domain protein 1 91 4e-18
sp|Q8K3B1|FBSP1_MOUSE F-box/SPRY-domain protein 1 (F-box on... 89 1e-17
sp|P21980|TGM2_HUMAN Protein-glutamine gamma-glutamyltransf... 32 1.9
sp|P54232|VEF_GVHA Viral-enhancing factor (VEF) (Enhancin) ... 32 2.4
sp|Q9TSW0|TRI15_PIG Tripartite motif protein 15 (Zinc finge... 31 4.2
sp|Q9LAI1|T2BLA_BACSQ Type IIT restriction enzyme BslI alph... 30 5.4
sp|O00499|BIN1_HUMAN Myc box dependent interacting protein ... 30 9.3
sp|Q8K3F6|KCNQ3_MOUSE Potassium voltage-gated channel subfa... 30 9.3
sp|O88944|KCNQ3_RAT Potassium voltage-gated channel subfami... 30 9.3
>sp|Q18223|FBSP1_CAEEL F-box/SPRY-domain protein 1 (F-box synaptic protein 1)
Length = 332
Score = 90.5 bits (223), Expect = 4e-18
Identities = 45/95 (47%), Positives = 65/95 (68%), Gaps = 2/95 (2%)
Frame = +2
Query: 296 WSSVHKSININLLPSNPYTFHRNPVANSTDGIRGNRGYSEGIHIWEINW--PLTMRGTHA 469
W++ S N N + +N +T HR PVA STDG+RG RG S+G+H ++I W PL GT A
Sbjct: 160 WNTSDISRN-NYIRTNGFTVHRQPVAQSTDGVRGKRGISKGVHAFDITWDGPL---GTVA 215
Query: 470 VVGVSTEKCQLQQDRYVSLVGIDDESWGWDIVNRI 574
VVG++T+ L YV+L+G DD+SWGW++V+ +
Sbjct: 216 VVGIATKHAALHCVGYVALLGSDDQSWGWNLVDNV 250
>sp|Q9V6L9|FBSP1_DROME F-box/SPRY-domain protein 1
Length = 255
Score = 90.5 bits (223), Expect = 4e-18
Identities = 44/92 (47%), Positives = 60/92 (65%)
Frame = +2
Query: 290 NTWSSVHKSININLLPSNPYTFHRNPVANSTDGIRGNRGYSEGIHIWEINWPLTMRGTHA 469
+ WS S N+ + P N +T HRNPVA STD RG G+ G H WE+ W + GT A
Sbjct: 81 HAWSPNDCSRNVYIKP-NGFTLHRNPVAQSTDAARGKIGFRHGRHTWEVIWEGPL-GTVA 138
Query: 470 VVGVSTEKCQLQQDRYVSLVGIDDESWGWDIV 565
V+G+ST++ LQ YV+L+G DD+SWGW++V
Sbjct: 139 VIGISTKEAALQCHGYVALLGSDDQSWGWNLV 170
>sp|Q8K3B1|FBSP1_MOUSE F-box/SPRY-domain protein 1 (F-box only protein 45)
Length = 286
Score = 89.0 bits (219), Expect = 1e-17
Identities = 44/96 (45%), Positives = 65/96 (67%), Gaps = 2/96 (2%)
Frame = +2
Query: 287 QNTWSSVHKSININLLPSNPYTFHRNPVANSTDGIRGNRGYSEGIHIWEINW--PLTMRG 460
Q+ +S+ S N+ + N +T HRNP+A STDG R G+SEG H WE+ W PL G
Sbjct: 111 QHAFSTNDCSRNV-YIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPL---G 166
Query: 461 THAVVGVSTEKCQLQQDRYVSLVGIDDESWGWDIVN 568
T AV+G++T++ +Q YV+L+G DD+SWGW++V+
Sbjct: 167 TVAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVD 202
Score = 32.0 bits (71), Expect = 1.9
Identities = 15/35 (42%), Positives = 22/35 (62%)
Frame = +1
Query: 652 CSMGKSFKIPSRIYLILDMYQGSLSFVIGNEFLGI 756
C+ ++I RI +ILDM +L+F G EFLG+
Sbjct: 218 CNNAPKYQIGERIRVILDMEDKTLAFERGYEFLGV 252
>sp|P21980|TGM2_HUMAN Protein-glutamine gamma-glutamyltransferase (Tissue
transglutaminase) (TGase C) (TGC) (TG(C))
(Tranglutaminase 2) (TGase-H)
Length = 687
Score = 32.0 bits (71), Expect = 1.9
Identities = 15/31 (48%), Positives = 20/31 (64%)
Frame = +2
Query: 242 PFMFEESNVDISEQEQNTWSSVHKSININLL 334
PF+F E N D+ + Q SVHKSIN +L+
Sbjct: 391 PFVFAEVNADVVDWIQQDDGSVHKSINRSLI 421
>sp|P54232|VEF_GVHA Viral-enhancing factor (VEF) (Enhancin) (104 kDa glycoprotein)
(Synergistic factor)
Length = 902
Score = 31.6 bits (70), Expect = 2.4
Identities = 29/94 (30%), Positives = 40/94 (42%), Gaps = 6/94 (6%)
Frame = +2
Query: 113 KKNLEKKYVDWIMKRFVFHRL-----SLITEINLPNSNETEVFISH-WIPFMFEESNVDI 274
K + + W + R V RL + EINL N E+ H +PF VD
Sbjct: 41 KFRVRADFAKWGITRPVIVRLLNNNRNTEREINLTNDQWIEMEHEHECVPF------VDW 94
Query: 275 SEQEQNTWSSVHKSININLLPSNPYTFHRNPVAN 376
E+NT + VH I+ +P Y F+ PV N
Sbjct: 95 PVGEKNTMAEVHFEIDGPHIPLPVYVFNTRPVEN 128
>sp|Q9TSW0|TRI15_PIG Tripartite motif protein 15 (Zinc finger protein B7)
Length = 461
Score = 30.8 bits (68), Expect = 4.2
Identities = 40/154 (25%), Positives = 61/154 (39%)
Frame = +2
Query: 104 EAEKKNLEKKYVDWIMKRFVFHRLSLITEINLPNSNETEVFISHWIPFMFEESNVDISEQ 283
EA +L KK D K + NL + ET+ I P S V +SE
Sbjct: 250 EAISPDLVKKIRDLHRKILTLPEMLRAFSENLVHHLETDSGIVTLDPLTASPSLV-LSED 308
Query: 284 EQNTWSSVHKSININLLPSNPYTFHRNPVANSTDGIRGNRGYSEGIHIWEINWPLTMRGT 463
+ SV + LP +P F PV + G+ G+S G H W++ L G
Sbjct: 309 RK----SVRYTRQKQNLPDSPLRFEGLPV------VLGSPGFSSGRHRWQVEVQLG-EGG 357
Query: 464 HAVVGVSTEKCQLQQDRYVSLVGIDDESWGWDIV 565
VGV E+ + + ++ G+ E W ++
Sbjct: 358 GCTVGVVGEEVRRKGEQ-----GLSAEEGVWAVI 386
>sp|Q9LAI1|T2BLA_BACSQ Type IIT restriction enzyme BslI alpha subunit (Endonuclease BslI
alpha subunit) (R.BslIalpha)
Length = 225
Score = 30.4 bits (67), Expect = 5.4
Identities = 20/80 (25%), Positives = 36/80 (45%), Gaps = 3/80 (3%)
Frame = +2
Query: 65 NNIFNMHLPHQITEAEKKNLEKKYVDWIMKRFVFHRLSLITEI---NLPNSNETEVFISH 235
N+ FN+ L H +T K+N K Y + + V + + E N NS+E + I H
Sbjct: 119 NSSFNVSLNHCVTCGSKENYYKTYRIYSYRTEVEPNIEALREFANNNKLNSDEDVIIIKH 178
Query: 236 WIPFMFEESNVDISEQEQNT 295
+ + + S+ ++ T
Sbjct: 179 LVDNVIHYGYIPYSKLDETT 198
>sp|O00499|BIN1_HUMAN Myc box dependent interacting protein 1 (Bridging integrator 1)
(Amphiphysin-like protein) (Amphiphysin II)
(Box-dependent myc-interacting protein 1)
Length = 593
Score = 29.6 bits (65), Expect = 9.3
Identities = 19/61 (31%), Positives = 28/61 (45%)
Frame = +2
Query: 122 LEKKYVDWIMKRFVFHRLSLITEINLPNSNETEVFISHWIPFMFEESNVDISEQEQNTWS 301
LEK W + H L+ + NL + E I +FEE NVD+ E+ + W+
Sbjct: 178 LEKAAPQWCQGKLQAH---LVAQTNLLRNQAEEELIK--AQKVFEEMNVDLQEELPSLWN 232
Query: 302 S 304
S
Sbjct: 233 S 233
>sp|Q8K3F6|KCNQ3_MOUSE Potassium voltage-gated channel subfamily KQT member 3
(Voltage-gated potassium channel subunit Kv7.3)
(Potassium channel alpha subunit KvLQT3) (KQT-like 3)
Length = 873
Score = 29.6 bits (65), Expect = 9.3
Identities = 16/71 (22%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Frame = +2
Query: 170 RLSLITEINLPNSNETEVFISHWIPFMFEESNVDISEQEQNTWSSVHKSININLL----P 337
+L + ++++ + +V ++ + P S + ++E N +S + K+I N P
Sbjct: 636 KLDFLVDMHMQHMERLQVHVTEYYPTKGASSPAEGEKKEDNRYSDL-KTIICNYSETGPP 694
Query: 338 SNPYTFHRNPV 370
PY+FH+ P+
Sbjct: 695 DPPYSFHQVPI 705
>sp|O88944|KCNQ3_RAT Potassium voltage-gated channel subfamily KQT member 3
(Voltage-gated potassium channel subunit Kv7.3)
(Potassium channel alpha subunit KvLQT3) (KQT-like 3)
Length = 873
Score = 29.6 bits (65), Expect = 9.3
Identities = 16/71 (22%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Frame = +2
Query: 170 RLSLITEINLPNSNETEVFISHWIPFMFEESNVDISEQEQNTWSSVHKSININLL----P 337
+L + ++++ + +V ++ + P S + ++E N +S + K+I N P
Sbjct: 636 KLDFLVDMHMQHMERLQVHVTEYYPTKGASSPAEGEKKEDNRYSDL-KTIICNYSESGPP 694
Query: 338 SNPYTFHRNPV 370
PY+FH+ P+
Sbjct: 695 DPPYSFHQVPI 705
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,051,614
Number of Sequences: 369166
Number of extensions: 1895320
Number of successful extensions: 5133
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4945
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5125
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7018522000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)