Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_A05
(849 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P19351|TNNT_DROME Troponin T, skeletal muscle (Upheld pr... 101 2e-21
sp|Q9XZ71|TNNT_PERAM Troponin T (TnT) 94 4e-19
sp|Q27371|TNNT_CAEEL Troponin T 76 1e-13
sp|P45379|TNNT2_HUMAN Troponin T, cardiac muscle (TnTc) (Ca... 64 7e-10
sp|P50752|TNNT2_MOUSE Troponin T, cardiac muscle (TnTc) (Ca... 63 9e-10
sp|P09741|TNNT2_RABIT Troponin T, cardiac muscle (TnTc) (Ca... 63 1e-09
sp|P50753|TNNT2_RAT Troponin T, cardiac muscle (TnTc) (Card... 62 2e-09
sp|P50751|TNNT2_SHEEP Troponin T, cardiac muscle (TnTc) (Ca... 60 8e-09
sp|P13789|TNNT2_BOVIN Troponin T, cardiac muscle (TnTc) (Ca... 60 1e-08
sp|P02642|TNNT2_CHICK Troponin T, cardiac muscle isoforms (... 59 1e-08
>sp|P19351|TNNT_DROME Troponin T, skeletal muscle (Upheld protein) (Intended thorax
protein)
Length = 397
Score = 101 bits (252), Expect = 2e-21
Identities = 76/213 (35%), Positives = 107/213 (50%), Gaps = 15/213 (7%)
Frame = +2
Query: 50 RTKTSNRPNFIINKRANNELEKDEPTKEEVAKSKEQLEAERKAILEQRIQALVIDGFDLQ 229
+ K PNF I K+ L E K+KEQLE E+K L RI+ L I+GF
Sbjct: 137 KDKDKKGPNFTIAKKDAGVLGLSSAAMER-NKTKEQLEEEKKISLSFRIKPLAIEGFGEA 195
Query: 230 KLKEKAKELHQNIYKLESEKYDLEQQFQRQTLDLMELAERARQMNKGGKGQKVNVAQTDA 409
KL+EKA+EL + I KLE+EKYDLE++ +RQ DL EL ER +Q + K K + +A
Sbjct: 196 KLREKAQELWELIVKLETEKYDLEERQKRQDYDLKELKERQKQQLR-HKALKKGL-DPEA 253
Query: 410 LPTKMSRAPPKVVMYSQYERVKDPRSFRDRSTVFDG---------------PLYSDYFTK 544
L K PPK+ + S+YER D RS+ D+ +F+G Y +
Sbjct: 254 LTGKY---PPKIQVASKYERRVDTRSYDDKKKLFEGGWDEISKDSNEKIWNEKKEQYTGR 310
Query: 545 IEPRFKVHMGEQGGEVVTENDAHHGSEAPAANE 643
+ + GE+ G+ E + G E A+E
Sbjct: 311 QKSKLPKWFGERPGKKAGEPETPEGEEDAKADE 343
>sp|Q9XZ71|TNNT_PERAM Troponin T (TnT)
Length = 384
Score = 94.4 bits (233), Expect = 4e-19
Identities = 65/160 (40%), Positives = 91/160 (56%)
Frame = +2
Query: 38 EADERTKTSNRPNFIINKRANNELEKDEPTKEEVAKSKEQLEAERKAILEQRIQALVIDG 217
+A + K PNF I K+ + + E K+KEQLE E+K L RI+ L I+
Sbjct: 131 QALKEQKQQKGPNFTIQKK--DPSFNMSSAQIERNKTKEQLEEEKKISLSFRIKPLEIEN 188
Query: 218 FDLQKLKEKAKELHQNIYKLESEKYDLEQQFQRQTLDLMELAERARQMNKGGKGQKVNVA 397
++ KLK KA EL I KLE+EKYDLE++ +RQ DL EL ER +Q + K K +
Sbjct: 189 LNVDKLKVKATELWDAIVKLETEKYDLEERQKRQDYDLKELKERQKQQLR-HKALKKGL- 246
Query: 398 QTDALPTKMSRAPPKVVMYSQYERVKDPRSFRDRSTVFDG 517
+AL K PPK+ + S+YER D RS+ D+ +F+G
Sbjct: 247 DPEALTGKY---PPKIQVASKYERRVDTRSYDDKKKLFEG 283
>sp|Q27371|TNNT_CAEEL Troponin T
Length = 405
Score = 76.3 bits (186), Expect = 1e-13
Identities = 47/125 (37%), Positives = 69/125 (55%)
Frame = +2
Query: 146 SKEQLEAERKAILEQRIQALVIDGFDLQKLKEKAKELHQNIYKLESEKYDLEQQFQRQTL 325
SKEQ+E ++ L + + G LKE+ + LH I KLE+EKYDLE++ +RQ
Sbjct: 203 SKEQMEDAKRNFLAAVCRVQDVSGLLPNDLKERIRGLHARIVKLEAEKYDLEKRRERQDY 262
Query: 326 DLMELAERARQMNKGGKGQKVNVAQTDALPTKMSRAPPKVVMYSQYERVKDPRSFRDRST 505
D+ EL ER RQ + K K + +A S PPK+ S+++R D RS+ DR
Sbjct: 263 DMKELHERQRQAAR-NKALKKGLDPEEA---ASSVHPPKITTASKFDRQTDRRSYGDRRY 318
Query: 506 VFDGP 520
+F+ P
Sbjct: 319 LFENP 323
>sp|P45379|TNNT2_HUMAN Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T)
(cTnT)
Length = 298
Score = 63.5 bits (153), Expect = 7e-10
Identities = 42/131 (32%), Positives = 67/131 (51%), Gaps = 15/131 (11%)
Frame = +2
Query: 29 KNKEADERTKTSNRPNFIINKRANNELEK--------------DEPTKEEVAKSKEQLEA 166
+N+ A+ER + N ++A +E K + + E K Q E
Sbjct: 159 QNRLAEERARREEEEN---RRKAEDEARKKKALSNMMHFGGYIQKQAQTERKSGKRQTER 215
Query: 167 ERKA-ILEQRIQALVIDGFDLQKLKEKAKELHQNIYKLESEKYDLEQQFQRQTLDLMELA 343
E+K IL +R + L ID + +L+EKAKEL Q+IY LE+EK+DL+++F++Q ++ L
Sbjct: 216 EKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLR 275
Query: 344 ERARQMNKGGK 376
R K K
Sbjct: 276 NRINDNQKVSK 286
>sp|P50752|TNNT2_MOUSE Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T)
(cTnT)
Length = 301
Score = 63.2 bits (152), Expect = 9e-10
Identities = 42/131 (32%), Positives = 68/131 (51%), Gaps = 15/131 (11%)
Frame = +2
Query: 29 KNKEADERTKTSNRPNFIINKRANNELEK--------------DEPTKEEVAKSKEQLEA 166
+N+ A+ER + N ++A +E K + + E K Q E
Sbjct: 162 QNRLAEERARREEEEN---RRKAEDEARKKKALSNMMHFGGYIQKQAQTERKSGKRQTER 218
Query: 167 ERKA-ILEQRIQALVIDGFDLQKLKEKAKELHQNIYKLESEKYDLEQQFQRQTLDLMELA 343
E+K IL +R +AL ID + +L+EKAKEL Q+I+ LE+EK+DL+++F++Q ++ L
Sbjct: 219 EKKKKILAERRKALAIDHLNEDQLREKAKELWQSIHNLEAEKFDLQEKFKQQKYEINVLR 278
Query: 344 ERARQMNKGGK 376
R K K
Sbjct: 279 NRINDNQKVSK 289
>sp|P09741|TNNT2_RABIT Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T)
(cTnT)
Length = 301
Score = 62.8 bits (151), Expect = 1e-09
Identities = 37/113 (32%), Positives = 64/113 (56%)
Frame = +2
Query: 38 EADERTKTSNRPNFIINKRANNELEKDEPTKEEVAKSKEQLEAERKAILEQRIQALVIDG 217
EA ++ SN +F ++K T+ + K + + E ++K + E+R + L ID
Sbjct: 184 EARKKKALSNMMHF------GGYIQKQAQTERKSGKRQTEREKKKKILAERR-KVLAIDH 236
Query: 218 FDLQKLKEKAKELHQNIYKLESEKYDLEQQFQRQTLDLMELAERARQMNKGGK 376
+ +L+EKAKEL Q+IY LE+EK+DL+++F++Q ++ L R K K
Sbjct: 237 LNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSK 289
>sp|P50753|TNNT2_RAT Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T)
(cTnT)
Length = 299
Score = 62.0 bits (149), Expect = 2e-09
Identities = 41/130 (31%), Positives = 67/130 (51%), Gaps = 14/130 (10%)
Frame = +2
Query: 29 KNKEADERTKTSNRPNFIINKRANNELEKD-------------EPTKEEVAKSKEQLEAE 169
+N+ A+ER + N ++A +E K + + E K Q E E
Sbjct: 161 QNRLAEERARREEEEN---RRKAEDEARKKKALSNMMHFGGYIQKAQTERKSGKRQTERE 217
Query: 170 RKA-ILEQRIQALVIDGFDLQKLKEKAKELHQNIYKLESEKYDLEQQFQRQTLDLMELAE 346
+K IL +R + L ID + +L+EKAKEL Q+I+ LE+EK+DL+++F++Q ++ L
Sbjct: 218 KKKKILAERRKVLAIDHLNEDQLREKAKELWQSIHNLEAEKFDLQEKFKQQKYEINVLRN 277
Query: 347 RARQMNKGGK 376
R K K
Sbjct: 278 RINDNQKVSK 287
>sp|P50751|TNNT2_SHEEP Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T)
(cTnT)
Length = 287
Score = 60.1 bits (144), Expect = 8e-09
Identities = 33/87 (37%), Positives = 52/87 (59%), Gaps = 1/87 (1%)
Frame = +2
Query: 119 EPTKEEVAKSKEQLEAERKA-ILEQRIQALVIDGFDLQKLKEKAKELHQNIYKLESEKYD 295
+ + E K Q E E+K IL +R + L ID + +L+EKA+EL Q+IY LE+EK+D
Sbjct: 189 QKAQAERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKARELWQSIYDLEAEKFD 248
Query: 296 LEQQFQRQTLDLMELAERARQMNKGGK 376
L+++F++Q ++ L R K K
Sbjct: 249 LQEKFKQQKYEINVLRNRVNDNQKVSK 275
>sp|P13789|TNNT2_BOVIN Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T)
(cTnT)
Length = 285
Score = 59.7 bits (143), Expect = 1e-08
Identities = 34/87 (39%), Positives = 51/87 (58%), Gaps = 1/87 (1%)
Frame = +2
Query: 119 EPTKEEVAKSKEQLEAERKA-ILEQRIQALVIDGFDLQKLKEKAKELHQNIYKLESEKYD 295
+ + E K Q E E+K IL +R + L ID + +L+EKAKEL Q IY LE+EK+D
Sbjct: 187 QKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQMIYDLEAEKFD 246
Query: 296 LEQQFQRQTLDLMELAERARQMNKGGK 376
L+++F++Q ++ L R K K
Sbjct: 247 LQEKFKQQKYEINVLRNRINDNQKVSK 273
>sp|P02642|TNNT2_CHICK Troponin T, cardiac muscle isoforms (TnTC)
Length = 302
Score = 59.3 bits (142), Expect = 1e-08
Identities = 37/89 (41%), Positives = 52/89 (58%), Gaps = 3/89 (3%)
Frame = +2
Query: 128 KEEVAKSKEQLEAERKA-ILEQRIQALVIDGFDLQKLKEKAKELHQNIYKLESEKYDLEQ 304
K E K+Q E E+K IL +R + L ID KL++KAKEL Q I LE+EK+DL++
Sbjct: 204 KSEKKGGKKQTEREKKKKILSERRKPLNIDHLSEDKLRDKAKELWQTIRDLEAEKFDLQE 263
Query: 305 QFQRQTLDLMELAERA--RQMNKGGKGQK 385
+F+RQ ++ L R Q KG K +
Sbjct: 264 KFKRQKYEINVLRNRVSDHQKVKGSKAAR 292
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,142,142
Number of Sequences: 369166
Number of extensions: 1775483
Number of successful extensions: 6940
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6262
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6857
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8341863645
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)