Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_A02
(403 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O43852|CALU_HUMAN Calumenin precursor (Crocalbin) (IEF S... 145 4e-35
sp|O35887|CALU_MOUSE Calumenin precursor (Crocalbin) 145 4e-35
sp|O35783|CALU_RAT Calumenin precursor (Crocalbin) (CBP-50) 142 2e-34
sp|Q15293|RCN1_HUMAN Reticulocalbin-1 precursor 133 1e-31
sp|Q05186|RCN1_MOUSE Reticulocalbin-1 precursor 130 1e-30
sp|O93434|RCN1_FUGRU Reticulocalbin-1 precursor 127 8e-30
sp|Q8BH97|RCN3_MOUSE Reticulocalbin-3 precursor 126 2e-29
sp|Q96D15|RCN3_HUMAN Reticulocalbin-3 precursor (EF-hand ca... 122 2e-28
sp|Q14257|RCN2_HUMAN Reticulocalbin-2 precursor (Calcium-bi... 79 4e-15
sp|Q62703|RCN2_RAT Reticulocalbin-2 precursor (Calcium-bind... 78 6e-15
>sp|O43852|CALU_HUMAN Calumenin precursor (Crocalbin) (IEF SSP 9302)
Length = 315
Score = 145 bits (365), Expect = 4e-35
Identities = 65/106 (61%), Positives = 84/106 (79%)
Frame = +1
Query: 1 DLDEYIHDMWTPEKNEEEPDWVKTERTQFIEHRDLNKDGKLDHDEIGKWILPLDHNHVTA 180
DL+EYI DM++ + N +EP+WVKTER QF+E RD N+DGK+D +E WILP D++H A
Sbjct: 209 DLEEYIGDMYSHDGNTDEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEA 268
Query: 181 ETNHLMEQTDANKDGYLTKVEILEKYDVFVGSQATDFGDALTRHAE 318
E HL+ ++D NKDG LTK EI++KYD+FVGSQATDFG+AL RH E
Sbjct: 269 EARHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDE 314
>sp|O35887|CALU_MOUSE Calumenin precursor (Crocalbin)
Length = 315
Score = 145 bits (365), Expect = 4e-35
Identities = 65/106 (61%), Positives = 84/106 (79%)
Frame = +1
Query: 1 DLDEYIHDMWTPEKNEEEPDWVKTERTQFIEHRDLNKDGKLDHDEIGKWILPLDHNHVTA 180
DL+EYI DM++ + N +EP+WVKTER QF+E RD N+DGK+D +E WILP D++H A
Sbjct: 209 DLEEYIGDMYSHDGNADEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEA 268
Query: 181 ETNHLMEQTDANKDGYLTKVEILEKYDVFVGSQATDFGDALTRHAE 318
E HL+ ++D NKDG LTK EI++KYD+FVGSQATDFG+AL RH E
Sbjct: 269 EARHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDE 314
>sp|O35783|CALU_RAT Calumenin precursor (Crocalbin) (CBP-50)
Length = 315
Score = 142 bits (358), Expect = 2e-34
Identities = 64/106 (60%), Positives = 83/106 (78%)
Frame = +1
Query: 1 DLDEYIHDMWTPEKNEEEPDWVKTERTQFIEHRDLNKDGKLDHDEIGKWILPLDHNHVTA 180
DL+EYI DM++ + N +EP WVKTER QF+E RD N+DGK+D +E WILP D++H A
Sbjct: 209 DLEEYIGDMYSHDGNADEPQWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEA 268
Query: 181 ETNHLMEQTDANKDGYLTKVEILEKYDVFVGSQATDFGDALTRHAE 318
E HL+ ++D +KDG LTK EI++KYD+FVGSQATDFG+AL RH E
Sbjct: 269 EARHLVYESDQDKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDE 314
>sp|Q15293|RCN1_HUMAN Reticulocalbin-1 precursor
Length = 331
Score = 133 bits (334), Expect = 1e-31
Identities = 66/108 (61%), Positives = 82/108 (75%), Gaps = 1/108 (0%)
Frame = +1
Query: 1 DLDEYIHDMWTPEKNEEEPDWVKTERTQFIEHRDLNKDGKLDHDEIGKWILPLDHNHVTA 180
D DEYI DM++ E+N EPDWV +ER QF E RDLNKDGKLD DEI WILP D++H A
Sbjct: 224 DQDEYIADMFSHEENGPEPDWVLSEREQFNEFRDLNKDGKLDKDEIRHWILPQDYDHAQA 283
Query: 181 ETNHLMEQTDANKDGYLTKVEILEKYDVFVGSQATDFGDALTR-HAEL 321
E HL+ ++D NKD LTK EILE +++FVGSQAT++G+ LT+ H EL
Sbjct: 284 EARHLVYESDKNKDEKLTKEEILENWNMFVGSQATNYGEDLTKNHDEL 331
Score = 28.5 bits (62), Expect = 5.2
Identities = 19/87 (21%), Positives = 40/87 (45%), Gaps = 1/87 (1%)
Frame = +1
Query: 55 PDWVKTERTQFIEHRDLNKDGKLDHDEIGKWILPLDHNHVTAETNHLMEQTDANKDGYLT 234
PD K + ++ D + DG + +E+ WI + ++ + + D +KD ++
Sbjct: 77 PDESKERLGKIVDRIDNDGDGFVTTEELKTWIKRVQKRYIFDNVAKVWKDYDRDKDDKIS 136
Query: 235 KVEILE-KYDVFVGSQATDFGDALTRH 312
E + Y ++G+ A +F D+ H
Sbjct: 137 WEEYKQATYGYYLGNPA-EFHDSSDHH 162
>sp|Q05186|RCN1_MOUSE Reticulocalbin-1 precursor
Length = 325
Score = 130 bits (327), Expect = 1e-30
Identities = 64/108 (59%), Positives = 81/108 (75%), Gaps = 1/108 (0%)
Frame = +1
Query: 1 DLDEYIHDMWTPEKNEEEPDWVKTERTQFIEHRDLNKDGKLDHDEIGKWILPLDHNHVTA 180
D DEYI DM++ E N EPDWV +ER QF + RDLNKDGKLD DEI WILP D++H A
Sbjct: 218 DQDEYIADMFSHEDNGPEPDWVLSEREQFNDFRDLNKDGKLDKDEIRHWILPQDYDHAQA 277
Query: 181 ETNHLMEQTDANKDGYLTKVEILEKYDVFVGSQATDFGDALTR-HAEL 321
E HL+ ++D NKD LTK EIL+ +++FVGSQAT++G+ LT+ H EL
Sbjct: 278 EARHLVYESDKNKDEMLTKEEILDNWNMFVGSQATNYGEDLTKNHDEL 325
Score = 28.9 bits (63), Expect = 4.0
Identities = 21/107 (19%), Positives = 49/107 (45%), Gaps = 6/107 (5%)
Frame = +1
Query: 10 EYIHDMWTPEKNEE-----EPDWVKTERTQFIEHRDLNKDGKLDHDEIGKWILPLDHNHV 174
+Y H+ + +++ + PD K + ++ D + DG + +E+ WI + ++
Sbjct: 51 QYDHEAFLGKEDSKTFDQLSPDESKERLGKIVDRIDSDGDGLVTTEELKLWIKRVQKRYI 110
Query: 175 TAETNHLMEQTDANKDGYLTKVEILE-KYDVFVGSQATDFGDALTRH 312
+ + D +KD ++ E + Y ++G+ A +F D+ H
Sbjct: 111 YDNVAKVWKDYDRDKDEKISWEEYKQATYGYYLGNPA-EFHDSSDHH 156
>sp|O93434|RCN1_FUGRU Reticulocalbin-1 precursor
Length = 322
Score = 127 bits (319), Expect = 8e-30
Identities = 62/108 (57%), Positives = 80/108 (74%), Gaps = 1/108 (0%)
Frame = +1
Query: 1 DLDEYIHDMWTPEKNEEEPDWVKTERTQFIEHRDLNKDGKLDHDEIGKWILPLDHNHVTA 180
D DEYI DM+ E EP+WVKTER QF + RDLNKDGK+D DEI WI+P D++H A
Sbjct: 215 DEDEYIADMFAHEDRGPEPEWVKTEREQFSDFRDLNKDGKMDLDEIRHWIMPQDYDHAQA 274
Query: 181 ETNHLMEQTDANKDGYLTKVEILEKYDVFVGSQATDFGDALTR-HAEL 321
E HL+ ++D +KD LTK EIL+ +++FVGSQAT++G+ LTR H EL
Sbjct: 275 EARHLVYESDKDKDQMLTKEEILDNWNMFVGSQATNYGEDLTRNHDEL 322
>sp|Q8BH97|RCN3_MOUSE Reticulocalbin-3 precursor
Length = 328
Score = 126 bits (316), Expect = 2e-29
Identities = 56/103 (54%), Positives = 77/103 (74%)
Frame = +1
Query: 4 LDEYIHDMWTPEKNEEEPDWVKTERTQFIEHRDLNKDGKLDHDEIGKWILPLDHNHVTAE 183
++EYI D+++ E EEEP WV+TER QF E RDLNKDG+LD E+G W+LP + E
Sbjct: 222 VEEYIADLYSEEPGEEEPAWVQTERQQFREFRDLNKDGRLDGSEVGYWVLPPSQDQPLVE 281
Query: 184 TNHLMEQTDANKDGYLTKVEILEKYDVFVGSQATDFGDALTRH 312
NHL+ ++D +KDG L+K EIL +++FVGSQAT++G+ LTRH
Sbjct: 282 ANHLLHESDTDKDGRLSKAEILSNWNMFVGSQATNYGEDLTRH 324
>sp|Q96D15|RCN3_HUMAN Reticulocalbin-3 precursor (EF-hand calcium-binding protein RLP49)
Length = 328
Score = 122 bits (307), Expect = 2e-28
Identities = 55/103 (53%), Positives = 76/103 (73%)
Frame = +1
Query: 4 LDEYIHDMWTPEKNEEEPDWVKTERTQFIEHRDLNKDGKLDHDEIGKWILPLDHNHVTAE 183
++EYI D+++ E EEEP WV+TER QF + RDLNKDG LD E+G W+LP + E
Sbjct: 222 VEEYIADLYSAEPGEEEPAWVQTERQQFRDFRDLNKDGHLDGSEVGHWVLPPAQDQPLVE 281
Query: 184 TNHLMEQTDANKDGYLTKVEILEKYDVFVGSQATDFGDALTRH 312
NHL+ ++D +KDG L+K EIL +++FVGSQAT++G+ LTRH
Sbjct: 282 ANHLLHESDTDKDGRLSKAEILGNWNMFVGSQATNYGEDLTRH 324
>sp|Q14257|RCN2_HUMAN Reticulocalbin-2 precursor (Calcium-binding protein ERC-55)
(E6-binding protein) (E6BP)
Length = 317
Score = 78.6 bits (192), Expect = 4e-15
Identities = 38/101 (37%), Positives = 62/101 (61%), Gaps = 1/101 (0%)
Frame = +1
Query: 4 LDEYIHDM-WTPEKNEEEPDWVKTERTQFIEHRDLNKDGKLDHDEIGKWILPLDHNHVTA 180
L+E++ D W P NE+ P+W+ E+ +F+ D + DG+LD E+ W++P +
Sbjct: 208 LEEFLGDYRWDPTANED-PEWILVEKDRFVNDYDKDNDGRLDPQELLPWVVPNNQGIAQE 266
Query: 181 ETNHLMEQTDANKDGYLTKVEILEKYDVFVGSQATDFGDAL 303
E HL+++ D N D L++ EILE D+F+ S+ATD+G L
Sbjct: 267 EALHLIDEMDLNGDKKLSEEEILENPDLFLTSEATDYGRQL 307
Score = 30.0 bits (66), Expect = 1.8
Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 1/100 (1%)
Frame = +1
Query: 1 DLDEYIHDMWTPEKNEEEPDWVKTERTQ-FIEHRDLNKDGKLDHDEIGKWILPLDHNHVT 177
D+DEY+ + EE + +R Q I+ DL+ DG L E+ WI ++
Sbjct: 50 DVDEYV------KLGHEE----QQKRLQAIIKKIDLDSDGFLTESELSSWIQMSFKHYAM 99
Query: 178 AETNHLMEQTDANKDGYLTKVEILEKYDVFVGSQATDFGD 297
E + D N D +T ++Y++ + + DF +
Sbjct: 100 QEAKQQFVEYDKNSDDTVT----WDEYNIQMYDRVIDFDE 135
>sp|Q62703|RCN2_RAT Reticulocalbin-2 precursor (Calcium-binding protein ERC-55)
(Taipoxin-associated calcium-binding protein 49)
(TCBP-49)
Length = 320
Score = 78.2 bits (191), Expect = 6e-15
Identities = 35/100 (35%), Positives = 59/100 (59%)
Frame = +1
Query: 4 LDEYIHDMWTPEKNEEEPDWVKTERTQFIEHRDLNKDGKLDHDEIGKWILPLDHNHVTAE 183
L+E++ D E+P+W+ E+ +F+ D + DG+LD E+ W++P + E
Sbjct: 211 LEEFLGDYRRDPTANEDPEWILVEKDRFVNDYDKDSDGRLDPQELLSWVVPNNQGIAQEE 270
Query: 184 TNHLMEQTDANKDGYLTKVEILEKYDVFVGSQATDFGDAL 303
HL+++ D N D L++ EILE D+F+ S+ATD+G L
Sbjct: 271 ALHLIDEMDLNSDKKLSEEEILENQDLFLTSEATDYGRQL 310
Score = 31.2 bits (69), Expect = 0.80
Identities = 24/99 (24%), Positives = 43/99 (43%)
Frame = +1
Query: 1 DLDEYIHDMWTPEKNEEEPDWVKTERTQFIEHRDLNKDGKLDHDEIGKWILPLDHNHVTA 180
D+DEY+ + EE + I+ D + DG L +E+ +WI ++
Sbjct: 53 DVDEYV------KLGHEEQ---QRRLQSIIKKIDSDSDGFLTENELSQWIQMSFKHYAMQ 103
Query: 181 ETNHLMEQTDANKDGYLTKVEILEKYDVFVGSQATDFGD 297
E + D N DG +T ++Y+V + + DF +
Sbjct: 104 EAKQQFVEYDKNSDGTVT----WDEYNVQMYDRVIDFDE 138
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,416,222
Number of Sequences: 369166
Number of extensions: 1152549
Number of successful extensions: 3320
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3163
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3296
length of database: 68,354,980
effective HSP length: 98
effective length of database: 50,250,950
effective search space used: 1758783250
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)