Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_006_O22
(781 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8BH04|PPCKM_MOUSE Phosphoenolpyruvate carboxykinase, mi... 291 1e-78
sp|P20007|PPCK_DROME Phosphoenolpyruvate carboxykinase [GTP... 291 1e-78
sp|Q16822|PPCKM_HUMAN Phosphoenolpyruvate carboxykinase, mi... 290 3e-78
sp|P07379|PPCKC_RAT Phosphoenolpyruvate carboxykinase, cyto... 289 5e-78
sp|Q9Z2V4|PPCKC_MOUSE Phosphoenolpyruvate carboxykinase, cy... 288 2e-77
sp|Q8HYZ4|PPCKC_BOVIN Phosphoenolpyruvate carboxykinase, cy... 288 2e-77
sp|P05153|PPCKC_CHICK Phosphoenolpyruvate carboxykinase, cy... 285 1e-76
sp|P29190|PPCK_HAECO Phosphoenolpyruvate carboxykinase [GTP... 285 1e-76
sp|P35558|PPCKC_HUMAN Phosphoenolpyruvate carboxykinase, cy... 282 6e-76
sp|Q5R5J1|PPCKC_PONPY Phosphoenolpyruvate carboxykinase, cy... 282 8e-76
>sp|Q8BH04|PPCKM_MOUSE Phosphoenolpyruvate carboxykinase, mitochondrial precursor [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-M)
Length = 640
Score = 291 bits (746), Expect = 1e-78
Identities = 130/217 (59%), Positives = 168/217 (77%), Gaps = 1/217 (0%)
Frame = +2
Query: 2 FCTPAKQCPIIDPKWEAPEGVHVEAIIFGGRRPEGVPLVYESLSWNHGVFIGGTVRSEAT 181
FC PA+QCPI+DP WEAPEGV ++AIIFGGRRP+GVPLVYE+ +W HGVF+G +RSE+T
Sbjct: 424 FCVPARQCPIMDPAWEAPEGVPIDAIIFGGRRPKGVPLVYEAFNWRHGVFVGSAMRSEST 483
Query: 182 AAAEFKGKQIMHDPFAMRPFFGYNFGHYMKHWIEL-GKKYPKVPKIYHVNWFRKSAKGEF 358
AAAE KGK IMHDPFAMRPFFGYNFG Y++HW+ + G+K ++P+I+HVNWFR+ G F
Sbjct: 484 AAAEHKGKTIMHDPFAMRPFFGYNFGRYLEHWLSMEGQKGARLPRIFHVNWFRRDEAGRF 543
Query: 359 LWPGYGENCRVLEWIMKRLNNEVQGVDSAIGLLPKVDDIDISGLSVTKADLEEVLSISKP 538
LWPG+GEN RVL+WI +RL E ++ IGL+PK +D+SGLS D ++ SI K
Sbjct: 544 LWPGFGENARVLDWICRRLEGEDSAQETPIGLVPKEGALDLSGLSA--VDTSQLFSIPKD 601
Query: 539 FWQNEVKEIKKYFEEQVGEDLPPEIAQELKNLEERVE 649
FW+ EV++I+ Y EQV +DLP E+ EL+ LE RV+
Sbjct: 602 FWEQEVRDIRGYLTEQVNQDLPKEVLAELEALEGRVQ 638
>sp|P20007|PPCK_DROME Phosphoenolpyruvate carboxykinase [GTP] (Phosphoenolpyruvate
carboxylase) (PEPCK)
Length = 647
Score = 291 bits (746), Expect = 1e-78
Identities = 134/216 (62%), Positives = 165/216 (76%)
Frame = +2
Query: 2 FCTPAKQCPIIDPKWEAPEGVHVEAIIFGGRRPEGVPLVYESLSWNHGVFIGGTVRSEAT 181
FCTPA QCPIID WE P GV + A++FGGRRP GVPL+YE+ W HGVFIG +RSEAT
Sbjct: 432 FCTPAAQCPIIDEAWEDPAGVPISAMLFGGRRPAGVPLIYEARDWTHGVFIGAAMRSEAT 491
Query: 182 AAAEFKGKQIMHDPFAMRPFFGYNFGHYMKHWIELGKKYPKVPKIYHVNWFRKSAKGEFL 361
AAAE KGK IMHDPFAMRPFFGYNFG Y+ HW+ + K+ +VPKI+HVNWFRKSA+G+F+
Sbjct: 492 AAAEHKGKVIMHDPFAMRPFFGYNFGDYVAHWLSMEKR-GQVPKIFHVNWFRKSAEGKFM 550
Query: 362 WPGYGENCRVLEWIMKRLNNEVQGVDSAIGLLPKVDDIDISGLSVTKADLEEVLSISKPF 541
WPGYGEN RVLEWI++R+N E VDSAIG +P +++ G+ K D++E+ S+ K F
Sbjct: 551 WPGYGENSRVLEWILRRVNGESCYVDSAIGHIPAEGALNLDGMK-DKVDVKEIFSLPKEF 609
Query: 542 WQNEVKEIKKYFEEQVGEDLPPEIAQELKNLEERVE 649
W EVK+I+ YFE QVG DLP I Q+L L RV+
Sbjct: 610 WSQEVKDIRTYFESQVGADLPASIYQQLDELSSRVD 645
>sp|Q16822|PPCKM_HUMAN Phosphoenolpyruvate carboxykinase, mitochondrial precursor [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-M)
Length = 640
Score = 290 bits (742), Expect = 3e-78
Identities = 129/216 (59%), Positives = 167/216 (77%), Gaps = 1/216 (0%)
Frame = +2
Query: 2 FCTPAKQCPIIDPKWEAPEGVHVEAIIFGGRRPEGVPLVYESLSWNHGVFIGGTVRSEAT 181
FC PA+QCPI+DP WEAPEGV ++AIIFGGRRP+GVPLVYE+ +W HGVF+G +RSE+T
Sbjct: 424 FCAPARQCPIMDPAWEAPEGVPIDAIIFGGRRPKGVPLVYEAFNWRHGVFVGRAMRSEST 483
Query: 182 AAAEFKGKQIMHDPFAMRPFFGYNFGHYMKHWIEL-GKKYPKVPKIYHVNWFRKSAKGEF 358
AAAE KGK IMHDPFAMRPFFGYNFGHY++HW+ + G+K ++P+I+HVNWFR+ G F
Sbjct: 484 AAAEHKGKIIMHDPFAMRPFFGYNFGHYLEHWLSMEGRKGAQLPRIFHVNWFRRDEAGHF 543
Query: 359 LWPGYGENCRVLEWIMKRLNNEVQGVDSAIGLLPKVDDIDISGLSVTKADLEEVLSISKP 538
LWPG+GEN RVL+WI +RL E ++ IGL+PK +D+SGL D ++ S+ K
Sbjct: 544 LWPGFGENARVLDWICRRLEGEDSARETPIGLVPKEGALDLSGLRA--IDTTQLFSLPKD 601
Query: 539 FWQNEVKEIKKYFEEQVGEDLPPEIAQELKNLEERV 646
FW+ EV++I+ Y EQV +DLP E+ EL+ LE RV
Sbjct: 602 FWEQEVRDIRSYLTEQVNQDLPKEVLAELEALERRV 637
>sp|P07379|PPCKC_RAT Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 289 bits (740), Expect = 5e-78
Identities = 133/216 (61%), Positives = 164/216 (75%), Gaps = 1/216 (0%)
Frame = +2
Query: 2 FCTPAKQCPIIDPKWEAPEGVHVEAIIFGGRRPEGVPLVYESLSWNHGVFIGGTVRSEAT 181
FCTPA QCPIIDP WE+PEGV +E IIFGGRRP GVPLVYE+LSW HGVF+G +RSEAT
Sbjct: 406 FCTPASQCPIIDPAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEAT 465
Query: 182 AAAEFKGKQIMHDPFAMRPFFGYNFGHYMKHWIELG-KKYPKVPKIYHVNWFRKSAKGEF 358
AAAE KGK IMHDPFAMRPFFGYNFG Y+ HW+ + + K+PKI+HVNWFRK G+F
Sbjct: 466 AAAEHKGKVIMHDPFAMRPFFGYNFGKYLAHWLSMAHRPAAKLPKIFHVNWFRKDKNGKF 525
Query: 359 LWPGYGENCRVLEWIMKRLNNEVQGVDSAIGLLPKVDDIDISGLSVTKADLEEVLSISKP 538
LWPG+GEN RVLEW+ R+ E + IG +PK D +++ GL ++EE+ ISK
Sbjct: 526 LWPGFGENSRVLEWMFGRIEGEDSAKLTPIGYVPKEDALNLKGLG--DVNVEELFGISKE 583
Query: 539 FWQNEVKEIKKYFEEQVGEDLPPEIAQELKNLEERV 646
FW+ EV+EI KY E+QV DLP EI +EL+ L++R+
Sbjct: 584 FWEKEVEEIDKYLEDQVNADLPYEIERELRALKQRI 619
>sp|Q9Z2V4|PPCKC_MOUSE Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 288 bits (736), Expect = 2e-77
Identities = 132/216 (61%), Positives = 165/216 (76%), Gaps = 1/216 (0%)
Frame = +2
Query: 2 FCTPAKQCPIIDPKWEAPEGVHVEAIIFGGRRPEGVPLVYESLSWNHGVFIGGTVRSEAT 181
FCTPA QCPIIDP WE+PEGV +E IIFGGRRPEGVPLVYE+LSW HGVF+G +RSEAT
Sbjct: 406 FCTPASQCPIIDPAWESPEGVPIEGIIFGGRRPEGVPLVYEALSWQHGVFVGAAMRSEAT 465
Query: 182 AAAEFKGKQIMHDPFAMRPFFGYNFGHYMKHWIELG-KKYPKVPKIYHVNWFRKSAKGEF 358
AAAE KGK IMHDPFAMRPFFGYNFG Y+ HW+ + + K+PKI+HVNWFRK G+F
Sbjct: 466 AAAEHKGKIIMHDPFAMRPFFGYNFGKYLAHWLSMAHRPAAKLPKIFHVNWFRKDKDGKF 525
Query: 359 LWPGYGENCRVLEWIMKRLNNEVQGVDSAIGLLPKVDDIDISGLSVTKADLEEVLSISKP 538
LWPG+GEN RVLEW+ R+ E + IG +PK + +++ GL ++EE+ ISK
Sbjct: 526 LWPGFGENSRVLEWMFGRIEGEDSAKLTPIGYIPKENALNLKGLG--GVNVEELFGISKE 583
Query: 539 FWQNEVKEIKKYFEEQVGEDLPPEIAQELKNLEERV 646
FW+ EV+EI +Y E+QV DLP EI +EL+ L++R+
Sbjct: 584 FWEKEVEEIDRYLEDQVNTDLPYEIERELRALKQRI 619
>sp|Q8HYZ4|PPCKC_BOVIN Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 288 bits (736), Expect = 2e-77
Identities = 132/216 (61%), Positives = 163/216 (75%), Gaps = 1/216 (0%)
Frame = +2
Query: 2 FCTPAKQCPIIDPKWEAPEGVHVEAIIFGGRRPEGVPLVYESLSWNHGVFIGGTVRSEAT 181
FCTPA QCPIIDP WE+PEGV +E IIFGGRRP GVPLVYE+LSW HGVF+G +RSEAT
Sbjct: 406 FCTPASQCPIIDPDWESPEGVPIEGIIFGGRRPVGVPLVYEALSWQHGVFVGAAMRSEAT 465
Query: 182 AAAEFKGKQIMHDPFAMRPFFGYNFGHYMKHWIELGKK-YPKVPKIYHVNWFRKSAKGEF 358
AAAE+KGK IMHDPFAM PFFGYNFG Y+ HW+ + ++ K+PKI+HVNWFRK G F
Sbjct: 466 AAAEYKGKVIMHDPFAMGPFFGYNFGQYLAHWLSMAQRPAAKLPKIFHVNWFRKDKAGRF 525
Query: 359 LWPGYGENCRVLEWIMKRLNNEVQGVDSAIGLLPKVDDIDISGLSVTKADLEEVLSISKP 538
LWPG+GEN RVLEW+ R+ E + IG +P D +D+ GL D++E+ ISK
Sbjct: 526 LWPGFGENSRVLEWMFNRVVGEGGASVTPIGYIPDEDALDLRGLG--DVDVKELFHISKE 583
Query: 539 FWQNEVKEIKKYFEEQVGEDLPPEIAQELKNLEERV 646
FW+ EV+EI+KY EEQV DLPPEI ++ L++R+
Sbjct: 584 FWEEEVEEIQKYLEEQVNVDLPPEIKNQVLALKQRI 619
>sp|P05153|PPCKC_CHICK Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 285 bits (729), Expect = 1e-76
Identities = 131/217 (60%), Positives = 164/217 (75%), Gaps = 1/217 (0%)
Frame = +2
Query: 2 FCTPAKQCPIIDPKWEAPEGVHVEAIIFGGRRPEGVPLVYESLSWNHGVFIGGTVRSEAT 181
FCTPA QCPI+DP WE+PEGV +E IIFGGRRP GVPLVYE+ +W HGVFIG +RSEAT
Sbjct: 406 FCTPASQCPIMDPAWESPEGVPIEGIIFGGRRPAGVPLVYEAFNWQHGVFIGAAMRSEAT 465
Query: 182 AAAEFKGKQIMHDPFAMRPFFGYNFGHYMKHWIELG-KKYPKVPKIYHVNWFRKSAKGEF 358
AAAE KGK IMHDPFAMRPFFGYNFG Y+ HW+ + + K+P+I+HVNWFRK ++G+F
Sbjct: 466 AAAEHKGKIIMHDPFAMRPFFGYNFGKYLAHWLSMAHRPAAKLPRIFHVNWFRKDSQGKF 525
Query: 359 LWPGYGENCRVLEWIMKRLNNEVQGVDSAIGLLPKVDDIDISGLSVTKADLEEVLSISKP 538
LWPGYGEN RVLEW+ R+ + +AIG +P +++ GL +L E+ +ISK
Sbjct: 526 LWPGYGENSRVLEWMFNRIQGKASAKSTAIGYIPADTALNLKGLE--DINLTELFNISKE 583
Query: 539 FWQNEVKEIKKYFEEQVGEDLPPEIAQELKNLEERVE 649
FW+ EV+EIK+YFE QV DLP EI +EL LE R++
Sbjct: 584 FWEKEVEEIKQYFEGQVNADLPYEIERELLALEMRIK 620
>sp|P29190|PPCK_HAECO Phosphoenolpyruvate carboxykinase [GTP] (Phosphoenolpyruvate
carboxylase) (PEPCK)
Length = 619
Score = 285 bits (728), Expect = 1e-76
Identities = 130/216 (60%), Positives = 166/216 (76%), Gaps = 1/216 (0%)
Frame = +2
Query: 2 FCTPAKQCPIIDPKWEAPEGVHVEAIIFGGRRPEGVPLVYESLSWNHGVFIGGTVRSEAT 181
F PA QCPII P+WE+P+GV ++AIIFGGRRP GVPLV+E+ SW HG+F G ++SEAT
Sbjct: 402 FAAPASQCPIIHPEWESPKGVPIDAIIFGGRRPAGVPLVFETRSWLHGIFTGACLKSEAT 461
Query: 182 AAAEFKGKQIMHDPFAMRPFFGYNFGHYMKHWIELGKKYPKVPKIYHVNWFRKSAKGEFL 361
AAAE KGK +MHDP AMRPF GYNFGHY++HWI+L K KVPKIYHVNWFR+ A +FL
Sbjct: 462 AAAEHKGKTVMHDPMAMRPFMGYNFGHYLQHWIDLNKDGRKVPKIYHVNWFRRDANNKFL 521
Query: 362 WPGYGENCRVLEWIMKRLNNEVQ-GVDSAIGLLPKVDDIDISGLSVTKADLEEVLSISKP 538
WPGYG+N RV++WI++RL+ E GVD+ IG++PK I+ SGL + D E++S+ K
Sbjct: 522 WPGYGQNIRVIDWIVRRLDGEPDIGVDTPIGIVPKKGAINASGLPDIQWD--ELMSVPKE 579
Query: 539 FWQNEVKEIKKYFEEQVGEDLPPEIAQELKNLEERV 646
+W N+ KEI+K+ EEQVG DLP EI E+ EER+
Sbjct: 580 YWTNDAKEIRKFLEEQVGPDLPKEIRAEMDAQEERI 615
>sp|P35558|PPCKC_HUMAN Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 282 bits (722), Expect = 6e-76
Identities = 129/216 (59%), Positives = 165/216 (76%), Gaps = 1/216 (0%)
Frame = +2
Query: 2 FCTPAKQCPIIDPKWEAPEGVHVEAIIFGGRRPEGVPLVYESLSWNHGVFIGGTVRSEAT 181
FCTPA QCPIID WE+PEGV +E IIFGGRRP GVPLVYE+LSW HGVF+G +RSEAT
Sbjct: 406 FCTPASQCPIIDAAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEAT 465
Query: 182 AAAEFKGKQIMHDPFAMRPFFGYNFGHYMKHWIELGK-KYPKVPKIYHVNWFRKSAKGEF 358
AAAE KGK IMHDPFAMRPFFGYNFG Y+ HW+ + + K+PKI+HVNWFRK +G+F
Sbjct: 466 AAAEHKGKIIMHDPFAMRPFFGYNFGKYLAHWLSMAQHPAAKLPKIFHVNWFRKDKEGKF 525
Query: 359 LWPGYGENCRVLEWIMKRLNNEVQGVDSAIGLLPKVDDIDISGLSVTKADLEEVLSISKP 538
LWPG+GEN RVLEW+ R++ + + IG +PK D +++ GL ++ E+ SISK
Sbjct: 526 LWPGFGENSRVLEWMFNRIDGKASTKLTPIGYIPKEDALNLKGLG--HINMMELFSISKE 583
Query: 539 FWQNEVKEIKKYFEEQVGEDLPPEIAQELKNLEERV 646
FW+ EV++I+KY E+QV DLP EI +E+ L++R+
Sbjct: 584 FWEKEVEDIEKYLEDQVNADLPCEIEREILALKQRI 619
>sp|Q5R5J1|PPCKC_PONPY Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 282 bits (721), Expect = 8e-76
Identities = 129/216 (59%), Positives = 165/216 (76%), Gaps = 1/216 (0%)
Frame = +2
Query: 2 FCTPAKQCPIIDPKWEAPEGVHVEAIIFGGRRPEGVPLVYESLSWNHGVFIGGTVRSEAT 181
FCTPA QCPIID WE+PEGV +E IIFGGRRP GVPLVYE+LSW HGVF+G +RSEAT
Sbjct: 406 FCTPASQCPIIDAAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEAT 465
Query: 182 AAAEFKGKQIMHDPFAMRPFFGYNFGHYMKHWIELGK-KYPKVPKIYHVNWFRKSAKGEF 358
AAAE KGK IMHDPFAMRPFFGYNFG Y+ HW+ + + K+PKI+HVNWFRK +G+F
Sbjct: 466 AAAEHKGKIIMHDPFAMRPFFGYNFGKYLAHWLSMAQHPAAKLPKIFHVNWFRKDKEGKF 525
Query: 359 LWPGYGENCRVLEWIMKRLNNEVQGVDSAIGLLPKVDDIDISGLSVTKADLEEVLSISKP 538
LWPG+GEN RVLEW+ R++ + + IG +PK D +++ GL ++ E+ SISK
Sbjct: 526 LWPGFGENSRVLEWMFNRIDGKAGAKLTPIGYIPKEDALNLKGLG--HINVMELFSISKE 583
Query: 539 FWQNEVKEIKKYFEEQVGEDLPPEIAQELKNLEERV 646
FW+ EV++I+KY E+QV DLP EI +E+ L++R+
Sbjct: 584 FWEKEVEDIEKYLEDQVNADLPCEIEREILALKQRI 619
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,147,477
Number of Sequences: 369166
Number of extensions: 1508644
Number of successful extensions: 4830
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4625
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4759
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7308943600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)