Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_006_O10
(811 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P42932|TCPQ_MOUSE T-complex protein 1, theta subunit (TC... 298 9e-81
sp|P50990|TCPQ_HUMAN T-complex protein 1, theta subunit (TC... 296 4e-80
sp|P78921|TCPQ_SCHPO Probable T-complex protein 1, theta su... 224 3e-58
sp|P47079|TCPQ_YEAST T-complex protein 1, theta subunit (TC... 223 4e-58
sp|P47828|TCPQ_CANAL T-complex protein 1, theta subunit (TC... 185 1e-46
sp|Q58405|THS_METJA Thermosome subunit (Chaperonin subunit) 150 3e-36
sp|O93624|THS_METTL Thermosome subunit (Chaperonin subunit) 138 2e-32
sp|P50016|THS_METKA Thermosome subunit (Chaperonin-like com... 138 2e-32
sp|O26885|THSB_METTH Thermosome beta subunit (Thermosome su... 137 5e-32
sp|Q9V2Q7|THS_PYRAB Thermosome subunit (Chaperonin subunit) 132 9e-31
>sp|P42932|TCPQ_MOUSE T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 548
Score = 298 bits (764), Expect = 9e-81
Identities = 146/268 (54%), Positives = 201/268 (75%)
Frame = +2
Query: 8 FSCPFDQLQTETKGTVLINTAKELMDFSRGEEDQMEERVREIAETGCKVIVTGGKVGELA 187
+SCPFD + TETKGTVLI TA+ELM+FS+GEE+ M+ +V+ IA TG VIVTGGKV ++A
Sbjct: 242 YSCPFDGMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIAGTGANVIVTGGKVADIA 301
Query: 188 LHYANKYNLMVVKLSSKFDIRRVCKVTGATPIPKLSTPTQEELGYIASVRTEEIGKSTVV 367
LHYANKYN+M+V+L+SK+D+RR+CK GAT +PKL+ P QEE+G+ SV E+G + VV
Sbjct: 302 LHYANKYNIMLVRLNSKWDLRRLCKTVGATALPKLTPPVQEEMGHCDSVYLSEVGDTQVV 361
Query: 368 LFDQDVKEGAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIELAN 547
+F + ++GAIS+IV+RGS ++MD++ERA+DDGVNTFK LT++ R + G GATEIELA
Sbjct: 362 VFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAK 421
Query: 548 RLSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHHREGKTTFGII 727
+++ + T GL QYAIK+F AFE+I + L +N+G A E I++L + H+EG G+
Sbjct: 422 QITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYSVHQEGNKNVGLD 481
Query: 728 STSEGRKVDDAVEHQILDTYTAKYWGIR 811
+E V D +E ILDTY KYW I+
Sbjct: 482 IEAEVPAVKDMLEASILDTYLGKYWAIK 509
>sp|P50990|TCPQ_HUMAN T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
sp|Q5RAP1|TCPQ_PONPY T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 548
Score = 296 bits (758), Expect = 4e-80
Identities = 144/268 (53%), Positives = 201/268 (75%)
Frame = +2
Query: 8 FSCPFDQLQTETKGTVLINTAKELMDFSRGEEDQMEERVREIAETGCKVIVTGGKVGELA 187
+SCPFD + TETKGTVLI TA+ELM+FS+GEE+ M+ +V+ IA+TG V+VTGGKV ++A
Sbjct: 242 YSCPFDGMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIADTGANVVVTGGKVADMA 301
Query: 188 LHYANKYNLMVVKLSSKFDIRRVCKVTGATPIPKLSTPTQEELGYIASVRTEEIGKSTVV 367
LHYANKYN+M+V+L+SK+D+RR+CK GAT +P+L+ P EE+G+ SV E+G + VV
Sbjct: 302 LHYANKYNIMLVRLNSKWDLRRLCKTVGATALPRLTPPVLEEMGHCDSVYLSEVGDTQVV 361
Query: 368 LFDQDVKEGAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIELAN 547
+F + ++GAIS+IV+RGS ++MD++ERA+DDGVNTFK LT++ R + G GATEIELA
Sbjct: 362 VFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAK 421
Query: 548 RLSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHHREGKTTFGII 727
+++ + T GL QYAIK+F AFE+I + L +N+G A E I++L A H+EG G+
Sbjct: 422 QITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVGLD 481
Query: 728 STSEGRKVDDAVEHQILDTYTAKYWGIR 811
+E V D +E ILDTY KYW I+
Sbjct: 482 IEAEVPAVKDMLEAGILDTYLGKYWAIK 509
>sp|P78921|TCPQ_SCHPO Probable T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 546
Score = 224 bits (570), Expect = 3e-58
Identities = 115/269 (42%), Positives = 173/269 (64%), Gaps = 1/269 (0%)
Frame = +2
Query: 8 FSCPFDQLQTETKGTVLINTAKELMDFSRGEEDQMEERVREIAETGCKVIVTGGKVGELA 187
FSCP D QTETKGTVL++ A+E++DFS+GEE+ +E ++EI + G +V+VT G V +L
Sbjct: 242 FSCPLDISQTETKGTVLLHNAQEMLDFSKGEENLIESHIKEIYDAGVRVVVTSGNVNDLV 301
Query: 188 LHYANKYNLMVVKLSSKFDIRRVCKVTGATPIPKLSTPTQEELGYIASVRTEEIGKSTVV 367
LHY N++ ++V+++ SKF++RR+C+V GATP+ ++ P EE+G + V T EIG V
Sbjct: 302 LHYLNRFEILVIRVPSKFELRRLCRVVGATPLARMGVPMPEEMGSVDVVETIEIGGDRVT 361
Query: 368 LFDQDVKEGAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIELAN 547
+F Q ++IV+RG+ +D++ERAIDDGVN K L K+ R + GAGA++++L
Sbjct: 362 VFRQVEDITRTATIVLRGATKTYLDDLERAIDDGVNIVKALVKDNRLIFGAGASDMQLCI 421
Query: 548 RLSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAEL-KAHHREGKTTFGI 724
RL G+ Q+AIKQ+ AFE + + + +NAG + T+ I++L AHH+E + G+
Sbjct: 422 RLISVGEKTPGIYQHAIKQYGEAFEVVPRTISENAGLDPTDVISKLYAAHHKENGESIGV 481
Query: 725 ISTSEGRKVDDAVEHQILDTYTAKYWGIR 811
E DA E I D AK IR
Sbjct: 482 DVECENDGTLDAKEAGIFDVLLAKKSAIR 510
>sp|P47079|TCPQ_YEAST T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 568
Score = 223 bits (569), Expect = 4e-58
Identities = 113/233 (48%), Positives = 162/233 (69%), Gaps = 3/233 (1%)
Frame = +2
Query: 8 FSCPFDQLQTETKGTVLINTAKELMDFSRGEEDQMEERVREIAETGCKVIVTGGKVGELA 187
F+CP D TETKGTVL++ A+E++DFS+GEE Q++ ++EIA+ G + IV G VGELA
Sbjct: 250 FTCPLDIANTETKGTVLLHNAQEMLDFSKGEEKQIDAMMKEIADMGVECIVAGAGVGELA 309
Query: 188 LHYANKYNLMVVKLSSKFDIRRVCKVTGATPIPKLSTPTQEELGYIASVRTEEIGKSTVV 367
LHY N+Y ++V+K+ SKF++RR+C+V GATP+P+L PT EELG + +V+T EIG V
Sbjct: 310 LHYLNRYGILVLKVPSKFELRRLCRVCGATPLPRLGAPTPEELGLVETVKTMEIGGDRVT 369
Query: 368 LFDQDVKE-GAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEP--RYLAGAGATEIE 538
+F Q+ E S+I++RG+ + +D++ERAIDDGV K L K + L GAGATEIE
Sbjct: 370 VFKQEQGEISRTSTIILRGATQNNLDDIERAIDDGVAAVKGLMKPSGGKLLPGAGATEIE 429
Query: 539 LANRLSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHH 697
L +R++ + GL+Q AIKQF +AFE + + L + AG + E + L A H
Sbjct: 430 LISRITKYGERTPGLLQLAIKQFAVAFEVVPRTLAETAGLDVNEVLPNLYAAH 482
>sp|P47828|TCPQ_CANAL T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 540
Score = 185 bits (470), Expect = 1e-46
Identities = 97/224 (43%), Positives = 141/224 (62%)
Frame = +2
Query: 92 RGEEDQMEERVREIAETGCKVIVTGGKVGELALHYANKYNLMVVKLSSKFDIRRVCKVTG 271
R + + R+ G + ++ G VGELALHY NKY ++V+++ SKFD+RR+C+V G
Sbjct: 267 RAKNNSWTSCARKSTIQGLRWLLPGSSVGELALHYLNKYGILVLRVPSKFDLRRICQVCG 326
Query: 272 ATPIPKLSTPTQEELGYIASVRTEEIGKSTVVLFDQDVKEGAISSIVVRGSMYDMMDEVE 451
ATP+P+L PT +E+G I + T+EIG V +F QD ++IVVRG+ + +D++E
Sbjct: 327 ATPLPRLGAPTPDEMGEIDIIETKEIGGDRVTIFRQDESSSRTATIVVRGATQNNLDDIE 386
Query: 452 RAIDDGVNTFKCLTKEPRYLAGAGATEIELANRLSDFANTQTGLVQYAIKQFVLAFESIV 631
RAIDDGVN+ K L K+ R L GAGA EIEL R++ + +T GL+Q AIK F AFE I
Sbjct: 387 RAIDDGVNSIKGLIKDNRLLPGAGAVEIELMKRITAYQST-PGLLQLAIKSFAKAFEVIP 445
Query: 632 KVLCDNAGENATERIAELKAHHREGKTTFGIISTSEGRKVDDAV 763
+VL + +G +++E +++L A H E I G D AV
Sbjct: 446 RVLAETSGHDSSEILSKLHAAHAEDTGLRAGIDIDSGEVADTAV 489
>sp|Q58405|THS_METJA Thermosome subunit (Chaperonin subunit)
Length = 542
Score = 150 bits (380), Expect = 3e-36
Identities = 86/249 (34%), Positives = 136/249 (54%), Gaps = 1/249 (0%)
Frame = +2
Query: 11 SCPFDQLQTETKGTVLINTAKELMDFSRGEEDQMEERVREIAETGCKVIVTGGKVGELAL 190
+CP + +TET + I +LM+F EE +++ V +IA TG V+ + +LA
Sbjct: 240 NCPIEVKETETDAEIRITDPAKLMEFIEQEEKMIKDMVEKIAATGANVVFCQKGIDDLAQ 299
Query: 191 HYANKYNLMVVKLSSKFDIRRVCKVTGATPIPKLSTPTQEELGYIASVRTEEIGKSTVVL 370
HY K ++ V+ K D+ ++ K TGA + K+ T E+LG V ++ ++
Sbjct: 300 HYLAKKGILAVRRVKKSDMEKLAKATGARIVTKIDDLTPEDLGEAGLVEERKVAGDAMIF 359
Query: 371 FDQDVKEGAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIELANR 550
+Q A++ I+ RGS +++EV RAIDD + KC +E + +AG GATEIELA R
Sbjct: 360 VEQCKHPKAVT-ILARGSTEHVVEEVARAIDDAIGVVKCALEEGKIVAGGGATEIELAKR 418
Query: 551 LSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELK-AHHREGKTTFGII 727
L FA + G Q A+K F A E I + L +N+G + + + +L+ AH +EG +G +
Sbjct: 419 LRKFAESVAGREQLAVKAFADALEVIPRTLAENSGLDPIDMLVKLRAAHEKEGGEVYG-L 477
Query: 728 STSEGRKVD 754
EG VD
Sbjct: 478 DVFEGEVVD 486
>sp|O93624|THS_METTL Thermosome subunit (Chaperonin subunit)
Length = 544
Score = 138 bits (348), Expect = 2e-32
Identities = 77/267 (28%), Positives = 140/267 (52%)
Frame = +2
Query: 11 SCPFDQLQTETKGTVLINTAKELMDFSRGEEDQMEERVREIAETGCKVIVTGGKVGELAL 190
+CP + +TET + I +LM+F EE +++ V I +G V+ + +LA
Sbjct: 238 NCPIEVKETETDAEIRITDPTKLMEFIEQEEKMLKDMVDTIKASGANVLFCQKGIDDLAQ 297
Query: 191 HYANKYNLMVVKLSSKFDIRRVCKVTGATPIPKLSTPTQEELGYIASVRTEEIGKSTVVL 370
HY K ++ V+ K D+ ++ K TGA + + E+LG V +I ++
Sbjct: 298 HYLAKEGILAVRRVKKSDMEKLSKATGANVVTNIKDLKAEDLGEAGIVEERKIAGDAMI- 356
Query: 371 FDQDVKEGAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIELANR 550
F ++ K ++++RG+ +++EV RA+DD + C ++ + +AG GA EIELA +
Sbjct: 357 FVEECKHPKAVTMLIRGTTEHVIEEVARAVDDAIGVVACTIEDGKIVAGGGAAEIELAMK 416
Query: 551 LSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHHREGKTTFGIIS 730
L D+A +G Q A++ F A E + + L +NAG +A E + +L+A H EG + ++
Sbjct: 417 LRDYAEGVSGREQLAVRAFADALEVVPRTLAENAGLDAIEMLVKLRAKHAEGNNAYYGLN 476
Query: 731 TSEGRKVDDAVEHQILDTYTAKYWGIR 811
G V++ E+ +++ K I+
Sbjct: 477 VFTG-DVENMTENGVVEPLRVKTQAIQ 502
>sp|P50016|THS_METKA Thermosome subunit (Chaperonin-like complex) (CLIC)
Length = 545
Score = 138 bits (347), Expect = 2e-32
Identities = 78/262 (29%), Positives = 141/262 (53%)
Frame = +2
Query: 11 SCPFDQLQTETKGTVLINTAKELMDFSRGEEDQMEERVREIAETGCKVIVTGGKVGELAL 190
+CP + +TET + I ++L F EE + E V +IAETG V+ + +LA
Sbjct: 245 NCPIEVKETETDAEIRITDPEQLQAFIEEEERMLSEMVDKIAETGANVVFCQKGIDDLAQ 304
Query: 191 HYANKYNLMVVKLSSKFDIRRVCKVTGATPIPKLSTPTQEELGYIASVRTEEIGKSTVVL 370
HY K ++ V+ K D++++ + TGA + + ++E+LG V +++ ++
Sbjct: 305 HYLAKKGILAVRRVKKSDMQKLARATGARIVTNIDDLSEEDLGEAEVVEEKKVAGDKMI- 363
Query: 371 FDQDVKEGAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIELANR 550
F + K+ +I++RG ++DE ERAI+D + ++ + +AG GA E+E+A +
Sbjct: 364 FVEGCKDPKAVTILIRGGTEHVVDEAERAIEDAIGVVAAALEDGKVVAGGGAPEVEVARQ 423
Query: 551 LSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHHREGKTTFGIIS 730
L DFA+ G Q A++ F A E I + L +N+G + + + +L+A H +G+ T G I
Sbjct: 424 LRDFADGVEGREQLAVEAFADALEIIPRTLAENSGLDPIDVLVQLRAKHEDGQVTAG-ID 482
Query: 731 TSEGRKVDDAVEHQILDTYTAK 796
+G V D +E +++ K
Sbjct: 483 VYDG-DVKDMLEEGVVEPLRVK 503
>sp|O26885|THSB_METTH Thermosome beta subunit (Thermosome subunit 2) (Chaperonin beta
subunit)
Length = 538
Score = 137 bits (344), Expect = 5e-32
Identities = 80/267 (29%), Positives = 141/267 (52%)
Frame = +2
Query: 11 SCPFDQLQTETKGTVLINTAKELMDFSRGEEDQMEERVREIAETGCKVIVTGGKVGELAL 190
+CP + +TE + I ++ F EE + + V I +TG V+ + +LA
Sbjct: 236 NCPIEVKETEVDAEIRITDPSQMQAFIEQEEQMIRDMVNSIVDTGANVLFCQKGIDDLAQ 295
Query: 191 HYANKYNLMVVKLSSKFDIRRVCKVTGATPIPKLSTPTQEELGYIASVRTEEIGKSTVVL 370
HY K ++ V+ K D+ ++ K TGA + + + E+LG V ++I ++
Sbjct: 296 HYLAKAGVLAVRRVKKSDMEKLSKATGANIVTNIEDLSPEDLGEAGVVSEKKISGEEMI- 354
Query: 371 FDQDVKEGAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIELANR 550
F ++ KE +I+VRGS ++ EVERAI+D + ++ + +AG GA EIE+A R
Sbjct: 355 FVEECKEPKAVTILVRGSTEHVVSEVERAIEDAIGVVAATVEDGKVVAGGGAPEIEIAKR 414
Query: 551 LSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHHREGKTTFGIIS 730
L D+A++ +G Q A+ F A E + K L +NAG ++ + + +L+A H E +T+ I
Sbjct: 415 LKDYADSISGREQLAVSAFAEALEIVPKTLAENAGLDSIDVLVDLRAAHEE--STYMGID 472
Query: 731 TSEGRKVDDAVEHQILDTYTAKYWGIR 811
+G K+ D E +++ + K I+
Sbjct: 473 VFDG-KIVDMKEAGVIEPHRVKKQAIQ 498
>sp|Q9V2Q7|THS_PYRAB Thermosome subunit (Chaperonin subunit)
Length = 550
Score = 132 bits (333), Expect = 9e-31
Identities = 80/260 (30%), Positives = 135/260 (51%)
Frame = +2
Query: 32 QTETKGTVLINTAKELMDFSRGEEDQMEERVREIAETGCKVIVTGGKVGELALHYANKYN 211
+TET + I + ++L F EE ++E V +I E G V+ + +LA HY KY
Sbjct: 250 ETETDAEIRITSPEQLQAFLEQEEKMLKEMVDKIKEVGANVVFVQKGIDDLAQHYLAKYG 309
Query: 212 LMVVKLSSKFDIRRVCKVTGATPIPKLSTPTQEELGYIASVRTEEIGKSTVVLFDQDVKE 391
++ V+ K D+ ++ K TGA + + T E+LG V ++ ++ F + K
Sbjct: 310 ILAVRRVKKSDMEKLAKATGAKIVTNIRDLTPEDLGEAELVEERKVAGENMI-FVEGCKN 368
Query: 392 GAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIELANRLSDFANT 571
+I++RG ++DEVERA++D V K + ++ + +AG GA EIEL+ +L ++A
Sbjct: 369 PKAVTILIRGGTEHVVDEVERALEDAVKVVKDILEDGKIIAGGGAAEIELSIKLDEYAKE 428
Query: 572 QTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHHREGKTTFGIISTSEGRKV 751
G Q AI+ F A + I + L +NAG + E + ++ A H+E T G I EG
Sbjct: 429 VGGKEQLAIEAFAEALKVIPRTLAENAGLDPIETLVKVIAAHKEKGPTIG-IDVYEGEPA 487
Query: 752 DDAVEHQILDTYTAKYWGIR 811
D +E +++ K I+
Sbjct: 488 -DMMERGVIEPVRVKKQAIK 506
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,292,003
Number of Sequences: 369166
Number of extensions: 1676961
Number of successful extensions: 5336
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5005
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5262
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7715018400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)