Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_006_N23 (433 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q8TC41|IBR1_HUMAN IBR domain containing protein 1 65 5e-11 sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Tri... 41 0.001 sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Tri... 41 0.001 sp|Q9WVS6|PRKN2_MOUSE Parkin (Ubiquitin E3 ligase PRKN) 40 0.002 sp|Q9JK66|PRKN2_RAT Parkin (Ubiquitin E3 ligase PRKN) 40 0.002 sp|O60260|PRKN2_HUMAN Parkin (Ubiquitin E3 ligase PRKN) (Pa... 39 0.004 sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52... 39 0.005 sp|O76924|ARI2_DROME Ariadne-2 protein (Ari-2) 37 0.023 sp|Q6ZPS6|AKIB1_MOUSE Ankyrin repeat and IBR domain contain... 36 0.040 sp|Q9P2G1|AKIB1_HUMAN Ankyrin repeat and IBR domain contain... 36 0.040
>sp|Q8TC41|IBR1_HUMAN IBR domain containing protein 1 Length = 275 Score = 65.5 bits (158), Expect = 5e-11 Identities = 30/68 (44%), Positives = 40/68 (58%) Frame = +2 Query: 2 ERNGGCPHMECSKCKCSWCYDCGRRRIKVKHIPFMNHDSKFFILGCSKNFLASKPHLRRF 181 +R GC HM CS+C ++CY CG R +++ F +H S I GC +L +PHLRR Sbjct: 139 QRTEGCDHMTCSQCNTNFCYRCGERYRQLRF--FGDHTSNLSIFGCKYRYLPERPHLRRL 196 Query: 182 VRISVFCG 205 VR SV G Sbjct: 197 VRGSVCAG 204
>sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Triad1 protein) Length = 493 Score = 40.8 bits (94), Expect = 0.001 Identities = 14/22 (63%), Positives = 18/22 (81%) Frame = +2 Query: 2 ERNGGCPHMECSKCKCSWCYDC 67 E+NGGC HM+CSKCK +C+ C Sbjct: 305 EKNGGCNHMQCSKCKHDFCWMC 326
>sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48) Length = 492 Score = 40.8 bits (94), Expect = 0.001 Identities = 14/22 (63%), Positives = 18/22 (81%) Frame = +2 Query: 2 ERNGGCPHMECSKCKCSWCYDC 67 E+NGGC HM+CSKCK +C+ C Sbjct: 304 EKNGGCNHMQCSKCKHDFCWMC 325
>sp|Q9WVS6|PRKN2_MOUSE Parkin (Ubiquitin E3 ligase PRKN) Length = 464 Score = 40.4 bits (93), Expect = 0.002 Identities = 14/25 (56%), Positives = 19/25 (76%), Gaps = 2/25 (8%) Frame = +2 Query: 2 ERNGGCPHMEC--SKCKCSWCYDCG 70 E+NGGC HM+C +CK WC++CG Sbjct: 425 EKNGGCMHMKCPQPQCKLEWCWNCG 449
>sp|Q9JK66|PRKN2_RAT Parkin (Ubiquitin E3 ligase PRKN) Length = 465 Score = 40.4 bits (93), Expect = 0.002 Identities = 14/25 (56%), Positives = 19/25 (76%), Gaps = 2/25 (8%) Frame = +2 Query: 2 ERNGGCPHMEC--SKCKCSWCYDCG 70 E+NGGC HM+C +CK WC++CG Sbjct: 426 EKNGGCMHMKCPQPQCKLEWCWNCG 450
>sp|O60260|PRKN2_HUMAN Parkin (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2) Length = 465 Score = 39.3 bits (90), Expect = 0.004 Identities = 13/25 (52%), Positives = 19/25 (76%), Gaps = 2/25 (8%) Frame = +2 Query: 2 ERNGGCPHMEC--SKCKCSWCYDCG 70 E+NGGC HM+C +C+ WC++CG Sbjct: 426 EKNGGCMHMKCPQPQCRLEWCWNCG 450
>sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52-GCN3 intergenic region Length = 551 Score = 38.9 bits (89), Expect = 0.005 Identities = 19/49 (38%), Positives = 23/49 (46%) Frame = +2 Query: 2 ERNGGCPHMECSKCKCSWCYDCGRRRIKVKHIPFMNHDSKFFILGCSKN 148 E+NGGC HM CS CK +C+ C P+ H FF KN Sbjct: 349 EKNGGCNHMVCSSCKYEFCWIC--------EGPWAPHGKNFFQCTMYKN 389
>sp|O76924|ARI2_DROME Ariadne-2 protein (Ari-2) Length = 509 Score = 36.6 bits (83), Expect = 0.023 Identities = 12/22 (54%), Positives = 16/22 (72%) Frame = +2 Query: 2 ERNGGCPHMECSKCKCSWCYDC 67 E+NGGC HM+C CK +C+ C Sbjct: 319 EKNGGCNHMQCFNCKHDFCWMC 340
>sp|Q6ZPS6|AKIB1_MOUSE Ankyrin repeat and IBR domain containing protein 1 Length = 1087 Score = 35.8 bits (81), Expect = 0.040 Identities = 11/22 (50%), Positives = 17/22 (77%) Frame = +2 Query: 2 ERNGGCPHMECSKCKCSWCYDC 67 ++N GC HM+C+KCK +C+ C Sbjct: 530 QKNEGCNHMQCAKCKYDFCWIC 551
>sp|Q9P2G1|AKIB1_HUMAN Ankyrin repeat and IBR domain containing protein 1 Length = 1214 Score = 35.8 bits (81), Expect = 0.040 Identities = 11/22 (50%), Positives = 17/22 (77%) Frame = +2 Query: 2 ERNGGCPHMECSKCKCSWCYDC 67 ++N GC HM+C+KCK +C+ C Sbjct: 652 QKNEGCNHMQCAKCKYDFCWIC 673
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 45,224,133 Number of Sequences: 369166 Number of extensions: 745440 Number of successful extensions: 1603 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1558 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1597 length of database: 68,354,980 effective HSP length: 100 effective length of database: 49,881,480 effective search space used: 2144903640 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)