Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_006_M17 (910 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P13906|MTB1_BACSH Modification methylase BspRI (Cytosine... 37 0.076 sp|Q86UE8|TLK2_HUMAN Serine/threonine-protein kinase tousle... 37 0.100 sp|O55047|TLK2_MOUSE Serine/threonine-protein kinase tousle... 37 0.100 sp|O15205|FAT10_HUMAN Ubiquitin-like protein FAT10 (Diubiqu... 33 0.84 sp|Q8ICR0|CDPK2_PLAF7 Calcium-dependent protein kinase 2 (P... 33 1.1 sp|O15865|CDPK2_PLAFK Calcium-dependent protein kinase 2 (P... 33 1.1 sp|P06530|MTBR_BACSU Modification methylase BsuRI (Cytosine... 33 1.4 sp|P47460|HMW2_MYCGE Cytadherence high molecular weight pro... 33 1.4 sp|Q8K1Y2|KPCN_MOUSE Protein kinase C, nu type (nPKC-nu) 32 1.9 sp|O94806|KPCN_HUMAN Protein kinase C, nu type (nPKC-nu) (P... 32 1.9
>sp|P13906|MTB1_BACSH Modification methylase BspRI (Cytosine-specific methyltransferase BspRI) (M.BspRI) Length = 424 Score = 37.0 bits (84), Expect = 0.076 Identities = 19/59 (32%), Positives = 32/59 (54%) Frame = +2 Query: 506 DYILLFNEKKHQRNPFIYPYINLEDSFIKLMKIPDVKIDPEPFDTGMYSEIYKARDQVK 682 D+ + E H + PY+ LE++ I D+ +DP P+ TG YS I+ +R++ K Sbjct: 250 DFNYEYPEITHGNEEGLKPYVTLEEA------IGDLSLDPGPYFTGSYSTIFMSRNRKK 302
>sp|Q86UE8|TLK2_HUMAN Serine/threonine-protein kinase tousled-like 2 (Tousled-like kinase 2) (PKU-alpha) Length = 772 Score = 36.6 bits (83), Expect = 0.100 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 4/87 (4%) Frame = +2 Query: 641 GMYSEIYKARDQVKNQSIVLKRYISDDG---DLIEKYRKLINGLIDFQRKGGQERFVKLY 811 G +SE+YKA D + + + +K + + + E Y K ++ R VKLY Sbjct: 471 GGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLY 530 Query: 812 SFYP-DPCSFAIGMEWMEGGSMDNYVK 889 ++ D SF +E+ EG +D Y+K Sbjct: 531 DYFSLDTDSFCTVLEYCEGNDLDFYLK 557
>sp|O55047|TLK2_MOUSE Serine/threonine-protein kinase tousled-like 2 (Tousled-like kinase 2) Length = 718 Score = 36.6 bits (83), Expect = 0.100 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 4/87 (4%) Frame = +2 Query: 641 GMYSEIYKARDQVKNQSIVLKRYISDDG---DLIEKYRKLINGLIDFQRKGGQERFVKLY 811 G +SE+YKA D + + + +K + + + E Y K ++ R VKLY Sbjct: 417 GGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLY 476 Query: 812 SFYP-DPCSFAIGMEWMEGGSMDNYVK 889 ++ D SF +E+ EG +D Y+K Sbjct: 477 DYFSLDTDSFCTVLEYCEGNDLDFYLK 503
>sp|O15205|FAT10_HUMAN Ubiquitin-like protein FAT10 (Diubiquitin) Length = 165 Score = 33.5 bits (75), Expect = 0.84 Identities = 24/93 (25%), Positives = 45/93 (48%), Gaps = 2/93 (2%) Frame = +2 Query: 2 KIKQKIRDNLSCPKNVNIKLMKLKYNDTFLNDNELLLS--TVKEEGATVTFELYSENDAK 175 KIK+ +R P + L+ K L L S KE+ +T ++ +D + Sbjct: 32 KIKEHVRSKTKVPVQDQVLLLGSK----ILKPRRSLSSYGIDKEKTIHLTLKVVKPSDEE 87 Query: 176 NDVILLFQGDMPARQILQLPKTATIREVKAALE 274 + L+ GD R +LQ+ +++++ +VKA +E Sbjct: 88 LPLFLVESGDEAKRHLLQVRRSSSVAQVKAMIE 120
>sp|Q8ICR0|CDPK2_PLAF7 Calcium-dependent protein kinase 2 (PfCDPK2) Length = 509 Score = 33.1 bits (74), Expect = 1.1 Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 1/99 (1%) Frame = +2 Query: 599 KIPDVKIDPEPFDTGMYSEIYKARDQVKNQSIVLKRYISDDGDLIEKYRKLINGLIDFQR 778 K+ D I E G Y +YK D+V NQ +K D I ++ + I+ + Sbjct: 67 KLEDKYIIDEKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRLKNINRFFQ----EIEIMK 122 Query: 779 KGGQERFVKLYSFYPDPCSFAIGMEWMEGGSM-DNYVKN 892 K VKLY Y + + ME G + D+ ++N Sbjct: 123 KLDHPNIVKLYETYENDNYIYLIMELCSGRELFDSIIEN 161
>sp|O15865|CDPK2_PLAFK Calcium-dependent protein kinase 2 (PfCDPK2) Length = 513 Score = 33.1 bits (74), Expect = 1.1 Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 1/99 (1%) Frame = +2 Query: 599 KIPDVKIDPEPFDTGMYSEIYKARDQVKNQSIVLKRYISDDGDLIEKYRKLINGLIDFQR 778 K+ D I E G Y +YK D+V NQ +K D I ++ + I+ + Sbjct: 67 KLEDKYIIDEKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRLKNINRFFQ----EIEIMK 122 Query: 779 KGGQERFVKLYSFYPDPCSFAIGMEWMEGGSM-DNYVKN 892 K VKLY Y + + ME G + D+ ++N Sbjct: 123 KLDHPNIVKLYETYENDNYIYLIMELCSGRELFDSIIEN 161
>sp|P06530|MTBR_BACSU Modification methylase BsuRI (Cytosine-specific methyltransferase BsuRI) (M.BsuRI) Length = 436 Score = 32.7 bits (73), Expect = 1.4 Identities = 18/50 (36%), Positives = 26/50 (52%) Frame = +2 Query: 536 HQRNPFIYPYINLEDSFIKLMKIPDVKIDPEPFDTGMYSEIYKARDQVKN 685 H + P+ L DS I D+ DP P+ TG YS IY +R++ K+ Sbjct: 261 HGEETGLKPFKTLRDS------IGDLVTDPGPYFTGSYSSIYMSRNRKKS 304
>sp|P47460|HMW2_MYCGE Cytadherence high molecular weight protein 2 (Cytadherence accessory protein 2) Length = 1805 Score = 32.7 bits (73), Expect = 1.4 Identities = 20/94 (21%), Positives = 45/94 (47%), Gaps = 8/94 (8%) Frame = +2 Query: 524 NEKKHQRNPFIYPYINLEDSFIKLMKIPDVKIDPEPFDTGMYSEIYKARDQVKNQSIVL- 700 N+ ++ N I NL D+ + L++ P++ ++ + + + ++Y DQ++NQ +L Sbjct: 156 NQTINRLNQKINGNQNLIDNNVALLQNPNITVEKKNYLLNVIDQLYNELDQLENQKRLLS 215 Query: 701 -------KRYISDDGDLIEKYRKLINGLIDFQRK 781 + +S D +L Y + I F+ + Sbjct: 216 IEYENTYRELVSADNELQNVYENIDQNQIQFKHQ 249
>sp|Q8K1Y2|KPCN_MOUSE Protein kinase C, nu type (nPKC-nu) Length = 889 Score = 32.3 bits (72), Expect = 1.9 Identities = 30/87 (34%), Positives = 43/87 (49%), Gaps = 11/87 (12%) Frame = +2 Query: 101 ELLLSTVKEEGATVTFELYSEND--AKNDVILLFQGDMPARQILQLPKTA-TIRE---VK 262 EL LS VK+ ++ ++ + E D ILLF+ DM + ILQL +A I E V+ Sbjct: 79 ELSLSAVKDLVCSIVYQKFPECGFFGMYDKILLFRHDMNSENILQLITSADEIHEGDLVE 138 Query: 263 AALEKLQEIETFD-----LYNYSIELP 328 L L +E F LY +S + P Sbjct: 139 VVLSALATVEDFQIRPHALYVHSYKAP 165
>sp|O94806|KPCN_HUMAN Protein kinase C, nu type (nPKC-nu) (Protein kinase EPK2) Length = 890 Score = 32.3 bits (72), Expect = 1.9 Identities = 30/87 (34%), Positives = 43/87 (49%), Gaps = 11/87 (12%) Frame = +2 Query: 101 ELLLSTVKEEGATVTFELYSEND--AKNDVILLFQGDMPARQILQLPKTA-TIRE---VK 262 EL LS VK+ ++ ++ + E D ILLF+ DM + ILQL +A I E V+ Sbjct: 79 ELSLSAVKDLVCSIVYQKFPECGFFGMYDKILLFRHDMNSENILQLITSADEIHEGDLVE 138 Query: 263 AALEKLQEIETFD-----LYNYSIELP 328 L L +E F LY +S + P Sbjct: 139 VVLSALATVEDFQIRPHTLYVHSYKAP 165
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 99,823,682 Number of Sequences: 369166 Number of extensions: 1964691 Number of successful extensions: 5729 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5510 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5724 length of database: 68,354,980 effective HSP length: 110 effective length of database: 48,034,130 effective search space used: 9222552960 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)