Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_006_M06
(598 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5M8Y1|SPCS2_XENTR Probable signal peptidase complex sub... 96 9e-20
sp|Q28250|SPCS2_CANFA Signal peptidase complex subunit 2 (M... 94 2e-19
sp|Q15005|SPCS2_HUMAN Signal peptidase complex subunit 2 (M... 94 2e-19
sp|Q5RAY6|SPCS2_PONPY Signal peptidase complex subunit 2 (M... 94 2e-19
sp|Q9CYN2|SPCS2_MOUSE Signal peptidase complex subunit 2 (M... 94 2e-19
sp|Q4R512|SPCS2_MACFA Signal peptidase complex subunit 2 (M... 94 2e-19
sp|Q5BJI9|SPCS2_BRARE Probable signal peptidase complex sub... 94 2e-19
sp|Q9VYY2|SPCS2_DROME Probable signal peptidase complex sub... 69 9e-12
sp|Q615A2|SPCS2_CAEBR Probable signal peptidase complex sub... 62 1e-09
sp|Q9XWW1|SPCS2_CAEEL Probable signal peptidase complex sub... 60 4e-09
>sp|Q5M8Y1|SPCS2_XENTR Probable signal peptidase complex subunit 2 (Microsomal signal
peptidase 25 kDa subunit) (SPase 25 kDa subunit)
Length = 201
Score = 95.5 bits (236), Expect = 9e-20
Identities = 46/113 (40%), Positives = 66/113 (58%)
Frame = +2
Query: 14 VAVLYDWFYPFSASKLVLIVCVLLYFALTGLLTCYIMFVERSTFFLAHENDTAGLDKPIK 193
VA+++D+ +PF SK VL +CV+ YF + G+LT Y + E+S F +AH D AG+D
Sbjct: 72 VALVWDYLHPFPESKPVLAICVISYFLMMGILTIYTSYKEKSIFLVAHRKDPAGMDPDDI 131
Query: 194 WNFQSKMKKYQDKYELTIKREDLNAKQSNVMTESKSIAEFFDIKGNLRMDILE 352
W+ S +K++ DKY L + K +KSIA FFD G L MD+ E
Sbjct: 132 WHLSSSLKRFDDKYTLKVTYISGKTKAQRDAEFTKSIARFFDDNGTLVMDLFE 184
>sp|Q28250|SPCS2_CANFA Signal peptidase complex subunit 2 (Microsomal signal peptidase 25
kDa subunit) (SPase 25 kDa subunit)
Length = 226
Score = 94.4 bits (233), Expect = 2e-19
Identities = 46/113 (40%), Positives = 65/113 (57%)
Frame = +2
Query: 14 VAVLYDWFYPFSASKLVLIVCVLLYFALTGLLTCYIMFVERSTFFLAHENDTAGLDKPIK 193
VA+++D+ +PF SK VL +CV+ YF + G+LT Y + E+S F +AH D G+D
Sbjct: 97 VALIWDYMHPFPESKPVLALCVISYFVMMGILTIYTSYKEKSIFLVAHRKDPTGMDPDDI 156
Query: 194 WNFQSKMKKYQDKYELTIKREDLNAKQSNVMTESKSIAEFFDIKGNLRMDILE 352
W S +K++ DKY L + KQ +KSIA+FFD G L MD E
Sbjct: 157 WQLSSSLKRFDDKYTLKLTFISGRTKQQREAEFTKSIAKFFDHSGTLVMDAYE 209
>sp|Q15005|SPCS2_HUMAN Signal peptidase complex subunit 2 (Microsomal signal peptidase 25
kDa subunit) (SPase 25 kDa subunit)
Length = 226
Score = 94.4 bits (233), Expect = 2e-19
Identities = 46/113 (40%), Positives = 65/113 (57%)
Frame = +2
Query: 14 VAVLYDWFYPFSASKLVLIVCVLLYFALTGLLTCYIMFVERSTFFLAHENDTAGLDKPIK 193
VA+++D+ +PF SK VL +CV+ YF + G+LT Y + E+S F +AH D G+D
Sbjct: 97 VALIWDYMHPFPESKPVLALCVISYFVMMGILTIYTSYKEKSIFLVAHRKDPTGMDPDDI 156
Query: 194 WNFQSKMKKYQDKYELTIKREDLNAKQSNVMTESKSIAEFFDIKGNLRMDILE 352
W S +K++ DKY L + KQ +KSIA+FFD G L MD E
Sbjct: 157 WQLSSSLKRFDDKYTLKLTFISGRTKQQREAEFTKSIAKFFDHSGTLVMDAYE 209
>sp|Q5RAY6|SPCS2_PONPY Signal peptidase complex subunit 2 (Microsomal signal peptidase 25
kDa subunit) (SPase 25 kDa subunit)
Length = 226
Score = 94.4 bits (233), Expect = 2e-19
Identities = 46/113 (40%), Positives = 65/113 (57%)
Frame = +2
Query: 14 VAVLYDWFYPFSASKLVLIVCVLLYFALTGLLTCYIMFVERSTFFLAHENDTAGLDKPIK 193
VA+++D+ +PF SK VL +CV+ YF + G+LT Y + E+S F +AH D G+D
Sbjct: 97 VALIWDYMHPFPESKPVLALCVISYFVMMGILTIYTSYKEKSIFLVAHRKDPTGMDPDDI 156
Query: 194 WNFQSKMKKYQDKYELTIKREDLNAKQSNVMTESKSIAEFFDIKGNLRMDILE 352
W S +K++ DKY L + KQ +KSIA+FFD G L MD E
Sbjct: 157 WQLSSSLKRFDDKYTLKLTFISGRTKQQREAEFTKSIAKFFDHSGTLVMDAYE 209
>sp|Q9CYN2|SPCS2_MOUSE Signal peptidase complex subunit 2 (Microsomal signal peptidase 25
kDa subunit) (SPase 25 kDa subunit)
Length = 226
Score = 94.4 bits (233), Expect = 2e-19
Identities = 46/113 (40%), Positives = 65/113 (57%)
Frame = +2
Query: 14 VAVLYDWFYPFSASKLVLIVCVLLYFALTGLLTCYIMFVERSTFFLAHENDTAGLDKPIK 193
VA+++D+ +PF SK VL +CV+ YF + G+LT Y + E+S F +AH D G+D
Sbjct: 97 VALIWDYMHPFPESKPVLALCVISYFVMMGILTIYTSYKEKSIFLVAHRKDPTGMDPDDI 156
Query: 194 WNFQSKMKKYQDKYELTIKREDLNAKQSNVMTESKSIAEFFDIKGNLRMDILE 352
W S +K++ DKY L + KQ +KSIA+FFD G L MD E
Sbjct: 157 WQLSSSLKRFDDKYTLKLTFISGRTKQQREAEFTKSIAKFFDHSGTLVMDAYE 209
>sp|Q4R512|SPCS2_MACFA Signal peptidase complex subunit 2 (Microsomal signal peptidase 25
kDa subunit) (SPase 25 kDa subunit)
Length = 226
Score = 94.4 bits (233), Expect = 2e-19
Identities = 46/113 (40%), Positives = 65/113 (57%)
Frame = +2
Query: 14 VAVLYDWFYPFSASKLVLIVCVLLYFALTGLLTCYIMFVERSTFFLAHENDTAGLDKPIK 193
VA+++D+ +PF SK VL +CV+ YF + G+LT Y + E+S F +AH D G+D
Sbjct: 97 VALIWDYMHPFPESKPVLALCVISYFVMMGILTIYTSYKEKSIFLVAHRKDPTGMDPDDI 156
Query: 194 WNFQSKMKKYQDKYELTIKREDLNAKQSNVMTESKSIAEFFDIKGNLRMDILE 352
W S +K++ DKY L + KQ +KSIA+FFD G L MD E
Sbjct: 157 WQLSSSLKRFDDKYTLKLTFISGRTKQQREAEFTKSIAKFFDHSGTLVMDAYE 209
>sp|Q5BJI9|SPCS2_BRARE Probable signal peptidase complex subunit 2 (Microsomal signal
peptidase 25 kDa subunit) (SPase 25 kDa subunit)
Length = 201
Score = 94.4 bits (233), Expect = 2e-19
Identities = 46/115 (40%), Positives = 68/115 (59%)
Frame = +2
Query: 14 VAVLYDWFYPFSASKLVLIVCVLLYFALTGLLTCYIMFVERSTFFLAHENDTAGLDKPIK 193
VA+++D+ +PF SK VL CV+ YF + G+LT Y + E++ F +A + D AG+D
Sbjct: 72 VALIWDYLHPFPESKPVLACCVVSYFIMMGILTLYTSYKEKNIFLVAMQKDPAGMDPDHS 131
Query: 194 WNFQSKMKKYQDKYELTIKREDLNAKQSNVMTESKSIAEFFDIKGNLRMDILEKY 358
W S +K++ D+Y L + D KQS +KS++ FFD G L MD EKY
Sbjct: 132 WCLSSSLKRFDDQYTLRMSFTDGKTKQSRETEFTKSVSVFFDENGTLVMDQYEKY 186
>sp|Q9VYY2|SPCS2_DROME Probable signal peptidase complex subunit 2 (Microsomal signal
peptidase 25 kDa subunit) (SPase 25 kDa subunit)
Length = 199
Score = 68.9 bits (167), Expect = 9e-12
Identities = 39/105 (37%), Positives = 57/105 (54%)
Frame = +2
Query: 14 VAVLYDWFYPFSASKLVLIVCVLLYFALTGLLTCYIMFVERSTFFLAHENDTAGLDKPIK 193
+A +D+ +PF S+ VL+ VL YFAL G+LT + F E+ TF +A + D ++
Sbjct: 67 MAHAWDFTHPFPESRPVLLFSVLAYFALLGILTLHSSFREKGTFAVALQKDK---ERERL 123
Query: 194 WNFQSKMKKYQDKYELTIKREDLNAKQSNVMTESKSIAEFFDIKG 328
W S M+KY DKY LT+ D + + +KS A F D G
Sbjct: 124 WEASSDMRKYDDKYLLTLSVRDTKNGKRREQSSNKSCAAFIDQNG 168
>sp|Q615A2|SPCS2_CAEBR Probable signal peptidase complex subunit 2 (Microsomal signal
peptidase 25 kDa subunit) (SPase 25 kDa subunit)
Length = 180
Score = 62.0 bits (149), Expect = 1e-09
Identities = 34/111 (30%), Positives = 65/111 (58%), Gaps = 1/111 (0%)
Frame = +2
Query: 26 YDWFYPFSASKLVLIVCVLLYFALTGLLTCYIMFVERSTFFLAHENDTAGLDKPIKWNFQ 205
YD++ PF SK+VL+VC + YF G+L + +VE+ F+ A+E D + KW +
Sbjct: 62 YDFYAPFPKSKIVLLVCSVSYFICMGVLQLFQWYVEKDCFYEANEVDG---KQTRKWAWS 118
Query: 206 SKMKKYQDKYELTIK-REDLNAKQSNVMTESKSIAEFFDIKGNLRMDILEK 355
S++K + DKY L+ + +++ + Q ++ KSI + D G + + ++++
Sbjct: 119 SEIKAHDDKYVLSAEFKKEGRSGQGKII---KSIGAYIDNDGEIMIPLVQR 166
>sp|Q9XWW1|SPCS2_CAEEL Probable signal peptidase complex subunit 2 (Microsomal signal
peptidase 25 kDa subunit) (SPase 25 kDa subunit)
Length = 180
Score = 60.1 bits (144), Expect = 4e-09
Identities = 36/110 (32%), Positives = 58/110 (52%)
Frame = +2
Query: 26 YDWFYPFSASKLVLIVCVLLYFALTGLLTCYIMFVERSTFFLAHENDTAGLDKPIKWNFQ 205
YD++ PF SK+VL VC + YF G+L Y +VE+ + A E D + KW +
Sbjct: 62 YDYYEPFPKSKIVLAVCSVSYFICMGILQMYQWYVEKDCIYEATEVDG---KQSRKWAWS 118
Query: 206 SKMKKYQDKYELTIKREDLNAKQSNVMTESKSIAEFFDIKGNLRMDILEK 355
S++K + DKY T+ E +S +KSI + D G + + +++K
Sbjct: 119 SEIKAHDDKY--TLSAEFKKEGRSGQGKITKSIGAYIDNDGEIIVPLVKK 166
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,169,344
Number of Sequences: 369166
Number of extensions: 1035217
Number of successful extensions: 2800
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2651
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2778
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4553075865
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)