Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_006_L12
(498 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5R8X4|UE1D1_PONPY Ubiquitin-activating enzyme E1-domain... 144 2e-34
sp|Q9GZZ9|UE1D1_HUMAN Ubiquitin-activating enzyme E1-domain... 142 3e-34
sp|Q5M7A4|UE1D1_RAT Ubiquitin-activating enzyme E1-domain c... 129 3e-30
sp|Q8VE47|UE1D1_MOUSE Ubiquitin-activating enzyme E1-domain... 127 1e-29
sp|Q9UHK6|AMACR_HUMAN Alpha-methylacyl-CoA racemase (2-meth... 34 0.22
sp|Q03763|DSG1_BOVIN Desmoglein-1 precursor (Desmosomal gly... 33 0.29
sp|O07347|SRP54_THEAQ Signal recognition particle protein (... 33 0.49
sp|P26359|SWI4_SCHPO Mating-type switching protein swi4 31 1.9
sp|Q15554|TERF2_HUMAN Telomeric repeat binding factor 2 (TT... 30 3.2
sp|P25037|UBP1_YEAST Ubiquitin carboxyl-terminal hydrolase ... 30 3.2
>sp|Q5R8X4|UE1D1_PONPY Ubiquitin-activating enzyme E1-domain containing protein 1
(UFM1-activating enzyme)
Length = 404
Score = 144 bits (362), Expect = 2e-34
Identities = 78/161 (48%), Positives = 109/161 (67%), Gaps = 2/161 (1%)
Frame = +2
Query: 2 KRDGVCAASLPTTMAIVAGFLVQNSLKFLLNFGTVSEFIGYGALEDNFYKVSLKPNPECG 181
KR+GVCAASLPTTM +VAG LVQN LKFLLNFGTVS ++GY A++D F +S+KPNP+C
Sbjct: 245 KREGVCAASLPTTMGVVAGILVQNVLKFLLNFGTVSFYLGYNAMQDFFPTMSMKPNPQCD 304
Query: 182 DRFCLMRQAEYREILRNTVVNCEPIEDKEEIVHEDNEFQIELVSDEEDAVPGDLLRKSLN 361
DR C +Q EY++ + + E I++KEEI+HEDNE+ IELVS+ + + +
Sbjct: 305 DRNCRKQQEEYKKKVA-ALPKQEVIQEKEEIIHEDNEWGIELVSEVSEEELKNSSGPVPD 363
Query: 362 LGDGVKLAY--DPNQSGKGNEAFVDKTELSLDELMKQMKNL 478
L +G+ +AY Q E V+ + SL++LM +MKN+
Sbjct: 364 LPEGITVAYTIPKKQEDSVTEVTVEDSGESLEDLMAKMKNM 404
>sp|Q9GZZ9|UE1D1_HUMAN Ubiquitin-activating enzyme E1-domain containing protein 1
(UFM1-activating enzyme) (Ubiquitin-activating enzyme 5)
(ThiFP1)
Length = 404
Score = 142 bits (359), Expect = 3e-34
Identities = 77/161 (47%), Positives = 109/161 (67%), Gaps = 2/161 (1%)
Frame = +2
Query: 2 KRDGVCAASLPTTMAIVAGFLVQNSLKFLLNFGTVSEFIGYGALEDNFYKVSLKPNPECG 181
KR+GVCAASLPTTM +VAG LVQN LKFLLNFGTVS ++GY A++D F +S+KPNP+C
Sbjct: 245 KREGVCAASLPTTMGVVAGILVQNVLKFLLNFGTVSFYLGYNAMQDFFPTMSMKPNPQCD 304
Query: 182 DRFCLMRQAEYREILRNTVVNCEPIEDKEEIVHEDNEFQIELVSDEEDAVPGDLLRKSLN 361
DR C +Q EY++ + + E I+++EEI+HEDNE+ IELVS+ + + +
Sbjct: 305 DRNCRKQQEEYKKKVA-ALPKQEVIQEEEEIIHEDNEWGIELVSEVSEEELKNFSGPVPD 363
Query: 362 LGDGVKLAY--DPNQSGKGNEAFVDKTELSLDELMKQMKNL 478
L +G+ +AY Q E V+ + SL++LM +MKN+
Sbjct: 364 LPEGITVAYTIPKKQEDSVTELTVEDSGESLEDLMAKMKNM 404
>sp|Q5M7A4|UE1D1_RAT Ubiquitin-activating enzyme E1-domain containing protein 1
(UFM1-activating enzyme)
Length = 403
Score = 129 bits (325), Expect = 3e-30
Identities = 70/161 (43%), Positives = 102/161 (63%), Gaps = 2/161 (1%)
Frame = +2
Query: 2 KRDGVCAASLPTTMAIVAGFLVQNSLKFLLNFGTVSEFIGYGALEDNFYKVSLKPNPECG 181
KR+GVCAASLPTTM +VAG LVQN LKFLL FGTVS ++GY A++D F + +KPNP+C
Sbjct: 243 KREGVCAASLPTTMGVVAGILVQNVLKFLLKFGTVSFYLGYNAMQDFFPTMFMKPNPQCD 302
Query: 182 DRFCLMRQAEYREILRNTVVNCEPIEDKEEIVHEDNEFQIELVSDEEDAVPGDLLRKSLN 361
D+ C +Q EY++ +++EE+VHEDNE+ IELVS+ + +
Sbjct: 303 DKNCRKQQEEYKKRAPAQPTQETAPQEEEEVVHEDNEWGIELVSEVSEEELKNSSGPVPT 362
Query: 362 LGDGVKLAY--DPNQSGKGNEAFVDKTELSLDELMKQMKNL 478
L +G+ +AY + +E V+ + SL++LM +MK +
Sbjct: 363 LPEGITVAYTVPKKREDSVSEVTVEDSGESLEDLMARMKKM 403
>sp|Q8VE47|UE1D1_MOUSE Ubiquitin-activating enzyme E1-domain containing protein 1
(UFM1-activating enzyme)
Length = 403
Score = 127 bits (319), Expect = 1e-29
Identities = 69/161 (42%), Positives = 99/161 (61%), Gaps = 2/161 (1%)
Frame = +2
Query: 2 KRDGVCAASLPTTMAIVAGFLVQNSLKFLLNFGTVSEFIGYGALEDNFYKVSLKPNPECG 181
KR+GVCAASLPTTM +VAG LVQN LKFLL FGTVS ++GY A++D F + +KPNP C
Sbjct: 243 KREGVCAASLPTTMGVVAGILVQNVLKFLLKFGTVSFYLGYNAMQDFFPTMFMKPNPHCD 302
Query: 182 DRFCLMRQAEYREILRNTVVNCEPIEDKEEIVHEDNEFQIELVSDEEDAVPGDLLRKSLN 361
D+ C +Q EY++ +++ E+VHEDNE+ IELVS+ + +
Sbjct: 303 DKNCRKQQEEYKKRAAALPTQEAEPQEEAEVVHEDNEWGIELVSEVSEEELKNSSGPVPT 362
Query: 362 LGDGVKLAY--DPNQSGKGNEAFVDKTELSLDELMKQMKNL 478
L +G+ +AY +E V+ + SL++LM +MK +
Sbjct: 363 LPEGITVAYTVPKKTEDSASEVTVEDSGESLEDLMARMKTM 403
>sp|Q9UHK6|AMACR_HUMAN Alpha-methylacyl-CoA racemase (2-methylacyl-CoA racemase)
Length = 382
Score = 33.9 bits (76), Expect = 0.22
Identities = 29/97 (29%), Positives = 43/97 (44%), Gaps = 22/97 (22%)
Frame = +2
Query: 110 EFIGYGALEDNFYKVSLK---------PN-------PEC----GDRFCLMRQAEYREILR 229
EF+ GA+E FY++ +K PN PE D F +AE+ +I
Sbjct: 229 EFMAVGAIEPQFYELLIKGLGLKSDELPNQMSMDDWPEMKKKFADVFAKKTKAEWCQIFD 288
Query: 230 NTVVNCEPIEDKEEIVHEDN--EFQIELVSDEEDAVP 334
T P+ EE+VH D+ E + S+E+D P
Sbjct: 289 GTDACVTPVLTFEEVVHHDHNKERGSFITSEEQDVSP 325
>sp|Q03763|DSG1_BOVIN Desmoglein-1 precursor (Desmosomal glycoprotein 1) (DG1) (DGI)
(Pemphigus foliaceus antigen)
Length = 1043
Score = 33.5 bits (75), Expect = 0.29
Identities = 33/122 (27%), Positives = 49/122 (40%), Gaps = 6/122 (4%)
Frame = +2
Query: 47 IVAGFLVQNSLKFLLNFGTVSEFIGYGALEDNFYKVSLKPNPECGDRFCLMRQAEYRE-- 220
++ GFLV + FLL G GA + +P PEC D E +
Sbjct: 557 LIMGFLVLGLVPFLLMCCDCGGAPGGGA--------AFEPVPECSDGAIHSWAVEGAQAD 608
Query: 221 --ILRNTVVNCEPIEDKEEIVHEDNE--FQIELVSDEEDAVPGDLLRKSLNLGDGVKLAY 388
+L N+ V C P+ + I + DN + E + E + G L DGVK++
Sbjct: 609 PGVLANSAVPCIPVTNANVIEYVDNSGVYTNEYGAREMQDLGGGERTTGFELTDGVKMSG 668
Query: 389 DP 394
P
Sbjct: 669 GP 670
>sp|O07347|SRP54_THEAQ Signal recognition particle protein (Fifty-four homolog)
Length = 430
Score = 32.7 bits (73), Expect = 0.49
Identities = 20/53 (37%), Positives = 27/53 (50%)
Frame = +2
Query: 320 EDAVPGDLLRKSLNLGDGVKLAYDPNQSGKGNEAFVDKTELSLDELMKQMKNL 478
E P L + L +GD LA +G EA ELSL++ +KQM+NL
Sbjct: 280 EPFYPERLAGRILGMGDVASLAEKVRAAGLEAEAPKSAKELSLEDFLKQMQNL 332
>sp|P26359|SWI4_SCHPO Mating-type switching protein swi4
Length = 993
Score = 30.8 bits (68), Expect = 1.9
Identities = 27/71 (38%), Positives = 37/71 (52%), Gaps = 2/71 (2%)
Frame = +2
Query: 260 DKEEIVHEDNEFQIELVSDEEDAVPGDLLRKSLNLGDGVK--LAYDPNQSGKGNEAFVDK 433
DKE ++HE IEL+SD + VP + S DGV+ L PN GK +FV
Sbjct: 719 DKELLIHESRHPMIELLSD-KSFVPNHIHLSS----DGVRCLLITGPNMGGK--SSFV-- 769
Query: 434 TELSLDELMKQ 466
+L+L +M Q
Sbjct: 770 KQLALSAIMAQ 780
>sp|Q15554|TERF2_HUMAN Telomeric repeat binding factor 2 (TTAGGG repeat binding factor 2)
(Telomeric DNA binding protein)
Length = 500
Score = 30.0 bits (66), Expect = 3.2
Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 7/82 (8%)
Frame = +2
Query: 254 IEDKEEIVHEDNEFQIELVSDEEDAVPGDLLRKSLNLGDGVKLAYDPNQSGKGNEA---- 421
+E+KE V ED FQ++ D ED+ ++ + + + + G+GN A
Sbjct: 417 VEEKETWVEEDELFQVQAAPD-EDSTTNITKKQKWTVEESEWVKAGVQKYGEGNWAAISK 475
Query: 422 ---FVDKTELSLDELMKQMKNL 478
FV++T + + + + MK L
Sbjct: 476 NYPFVNRTAVMIKDRWRTMKRL 497
>sp|P25037|UBP1_YEAST Ubiquitin carboxyl-terminal hydrolase 1 (Ubiquitin thiolesterase 1)
(Ubiquitin-specific processing protease 1)
(Deubiquitinating enzyme 1)
Length = 809
Score = 30.0 bits (66), Expect = 3.2
Identities = 17/50 (34%), Positives = 26/50 (52%), Gaps = 10/50 (20%)
Frame = +2
Query: 215 REILRNTVVNCEPIEDKEEIVHEDN----------EFQIELVSDEEDAVP 334
+ I+ ++ V E ++D EE+ DN E Q+E SDEED +P
Sbjct: 612 KRIIEHSDVENENVKDNEELQEIDNVSLDEPKINVEDQLETSSDEEDVIP 661
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,282,536
Number of Sequences: 369166
Number of extensions: 1108669
Number of successful extensions: 4405
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4122
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4387
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 3119256630
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)