Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_006_K19
(501 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted pr... 183 2e-46
sp|P06797|CATL_MOUSE Cathepsin L precursor (Major excreted ... 182 5e-46
sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathe... 180 1e-45
sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine protei... 180 1e-45
sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L hea... 179 3e-45
sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathe... 178 7e-45
sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Catheps... 177 2e-44
sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathe... 177 2e-44
sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) ... 176 3e-44
sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precu... 176 4e-44
>sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted protein) (MEP) (Cyclic
protein 2) (CP-2) [Contains: Cathepsin L heavy chain;
Cathepsin L light chain]
Length = 334
Score = 183 bits (465), Expect = 2e-46
Identities = 89/148 (60%), Positives = 108/148 (72%), Gaps = 5/148 (3%)
Frame = +3
Query: 3 FAYIKQYG-IESEASYPYTANEGECSYNKAKVVANCTGFIDIPQNNENLLAASVATVGPI 179
F YIK+ G ++SE SYPY A +G C Y VAN TGF+DIPQ + L+ A VATVGPI
Sbjct: 187 FQYIKENGGLDSEESYPYEAKDGSCKYRAEYAVANDTGFVDIPQQEKALMKA-VATVGPI 245
Query: 180 SIGIDASQASFQFYKSGIYDEPQCSSTSLDHGVLAVGYG----TTNGRNFWIVKNSWGTS 347
S+ +DAS S QFY SGIY EP CSS LDHGVL VGYG +N +W+VKNSWG
Sbjct: 246 SVAMDASHPSLQFYSSGIYYEPNCSSKDLDHGVLVVGYGYEGTDSNKDKYWLVKNSWGKE 305
Query: 348 WGMNGYIEMSKDKNNQCGVATAASYPLV 431
WGM+GYI+++KD+NN CG+ATAASYP+V
Sbjct: 306 WGMDGYIKIAKDRNNHCGLATAASYPIV 333
>sp|P06797|CATL_MOUSE Cathepsin L precursor (Major excreted protein) (MEP) (p39 cysteine
proteinase) [Contains: Cathepsin L heavy chain;
Cathepsin L light chain]
Length = 334
Score = 182 bits (461), Expect = 5e-46
Identities = 88/148 (59%), Positives = 109/148 (73%), Gaps = 5/148 (3%)
Frame = +3
Query: 3 FAYIKQYG-IESEASYPYTANEGECSYNKAKVVANCTGFIDIPQNNENLLAASVATVGPI 179
F YIK+ G ++SE SYPY A +G C Y VAN TGF+DIPQ + L+ A VATVGPI
Sbjct: 187 FQYIKENGGLDSEESYPYEAKDGSCKYRAEFAVANDTGFVDIPQQEKALMKA-VATVGPI 245
Query: 180 SIGIDASQASFQFYKSGIYDEPQCSSTSLDHGVLAVGYG----TTNGRNFWIVKNSWGTS 347
S+ +DAS S QFY SGIY EP CSS +LDHGVL VGYG +N +W+VKNSWG+
Sbjct: 246 SVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKNSWGSE 305
Query: 348 WGMNGYIEMSKDKNNQCGVATAASYPLV 431
WGM GYI+++KD++N CG+ATAASYP+V
Sbjct: 306 WGMEGYIKIAKDRDNHCGLATAASYPVV 333
>sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 339
Score = 180 bits (457), Expect = 1e-45
Identities = 80/145 (55%), Positives = 109/145 (75%), Gaps = 2/145 (1%)
Frame = +3
Query: 3 FAYIKQYG-IESEASYPYTANEGECSYNKAKVVANCTGFIDIPQNNENLLAASVATVGPI 179
F YIK G I++E SYPY + C +NKA + A TGF+DIP+ +E + +VAT+GP+
Sbjct: 195 FRYIKDNGGIDTEKSYPYEGIDDSCHFNKATIGATDTGFVDIPEGDEEKMKKAVATMGPV 254
Query: 180 SIGIDASQASFQFYKSGIYDEPQCSSTSLDHGVLAVGYGT-TNGRNFWIVKNSWGTSWGM 356
S+ IDAS SFQ Y G+Y+EP+C +LDHGVL VGYGT +G ++W+VKNSWGT+WG
Sbjct: 255 SVAIDASHESFQLYSEGVYNEPECDEQNLDHGVLVVGYGTDESGMDYWLVKNSWGTTWGE 314
Query: 357 NGYIEMSKDKNNQCGVATAASYPLV 431
GYI+M++++NNQCG+ATA+SYP V
Sbjct: 315 QGYIKMARNQNNQCGIATASSYPTV 339
>sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine proteinase 1) [Contains: Cathepsin
L heavy chain; Cathepsin L light chain]
Length = 341
Score = 180 bits (457), Expect = 1e-45
Identities = 83/145 (57%), Positives = 109/145 (75%), Gaps = 2/145 (1%)
Frame = +3
Query: 3 FAYIKQYG-IESEASYPYTANEGECSYNKAKVVANCTGFIDIPQNNENLLAASVATVGPI 179
F YIK G I++E SYPY A + C +NK V A GF DIPQ +E +A +VATVGP+
Sbjct: 197 FRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPV 256
Query: 180 SIGIDASQASFQFYKSGIYDEPQCSSTSLDHGVLAVGYGT-TNGRNFWIVKNSWGTSWGM 356
S+ IDAS SFQFY G+Y+EPQC + +LDHGVL VG+GT +G ++W+VKNSWGT+WG
Sbjct: 257 SVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGD 316
Query: 357 NGYIEMSKDKNNQCGVATAASYPLV 431
G+I+M ++K NQCG+A+A+SYPLV
Sbjct: 317 KGFIKMLRNKENQCGIASASSYPLV 341
>sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L heavy chain; Cathepsin L light
chain]
Length = 217
Score = 179 bits (455), Expect = 3e-45
Identities = 88/145 (60%), Positives = 104/145 (71%), Gaps = 2/145 (1%)
Frame = +3
Query: 3 FAYIKQYG-IESEASYPYTANEGECSYNKAKVVANCTGFIDIPQNNENLLAASVATVGPI 179
F YIK+ G ++SE SYPY A + C+Y A TGF+DIPQ + L+ A VATVGPI
Sbjct: 74 FQYIKENGGLDSEESYPYEATDTSCNYKPEYSAAKDTGFVDIPQREKALMKA-VATVGPI 132
Query: 180 SIGIDASQASFQFYKSGIYDEPQCSSTSLDHGVLAVGYGTTNGRN-FWIVKNSWGTSWGM 356
S+ IDA +SFQFYKSGIY +P CSS LDHGVL VGYG N FWIVKNSWG WG
Sbjct: 133 SVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTNNKFWIVKNSWGPEWGN 192
Query: 357 NGYIEMSKDKNNQCGVATAASYPLV 431
GY++M+KD+NN CG+ATAASYP V
Sbjct: 193 KGYVKMAKDQNNHCGIATAASYPTV 217
>sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 334
Score = 178 bits (451), Expect = 7e-45
Identities = 89/149 (59%), Positives = 104/149 (69%), Gaps = 6/149 (4%)
Frame = +3
Query: 3 FAYIKQYG-IESEASYPYTANE-GECSYNKAKVVANCTGFIDIPQNNENLLAASVATVGP 176
F YIK G ++SE SYPY A + C+Y AN TGF+DIPQ + L+ A VATVGP
Sbjct: 187 FQYIKDNGGLDSEESYPYLATDTNSCNYKPECSAANDTGFVDIPQREKALMKA-VATVGP 245
Query: 177 ISIGIDASQASFQFYKSGIYDEPQCSSTSLDHGVLAVGYG----TTNGRNFWIVKNSWGT 344
IS+ IDA SFQFYKSGIY +P CS LDHGVL VGYG +N FWIVKNSWG
Sbjct: 246 ISVAIDAGHTSFQFYKSGIYYDPDCSCKDLDHGVLVVGYGFEGTDSNNNKFWIVKNSWGP 305
Query: 345 SWGMNGYIEMSKDKNNQCGVATAASYPLV 431
WG NGY++M+KD+NN CG+ATAASYP V
Sbjct: 306 EWGWNGYVKMAKDQNNHCGIATAASYPTV 334
>sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 334
Score = 177 bits (448), Expect = 2e-44
Identities = 87/149 (58%), Positives = 105/149 (70%), Gaps = 6/149 (4%)
Frame = +3
Query: 3 FAYIKQYG-IESEASYPYTANE-GECSYNKAKVVANCTGFIDIPQNNENLLAASVATVGP 176
F Y+K G +++E SYPY E C+Y AN TGF+DIPQ + L+ A VATVGP
Sbjct: 187 FQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKA-VATVGP 245
Query: 177 ISIGIDASQASFQFYKSGIYDEPQCSSTSLDHGVLAVGYG----TTNGRNFWIVKNSWGT 344
IS+ IDA +SFQFYKSGIY +P CSS LDHGVL VGYG +N FWIVKNSWG
Sbjct: 246 ISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWGP 305
Query: 345 SWGMNGYIEMSKDKNNQCGVATAASYPLV 431
WG NGY++M+KD+NN CG++TAASYP V
Sbjct: 306 EWGWNGYVKMAKDQNNHCGISTAASYPTV 334
>sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 333
Score = 177 bits (448), Expect = 2e-44
Identities = 87/148 (58%), Positives = 105/148 (70%), Gaps = 5/148 (3%)
Frame = +3
Query: 3 FAYIKQYG-IESEASYPYTANEGE-CSYNKAKVVANCTGFIDIPQNNENLLAASVATVGP 176
F Y+K G ++SE SYPY + E C+Y AN TGF+D+PQ + L+ A VAT+GP
Sbjct: 187 FRYVKDNGGLDSEESYPYLGRDTETCNYKPECSAANDTGFVDLPQREKALMKA-VATLGP 245
Query: 177 ISIGIDASQASFQFYKSGIYDEPQCSSTSLDHGVLAVGYG---TTNGRNFWIVKNSWGTS 347
IS+ IDA SFQFYKSGIY +P CSS LDHGVL VGYG T + FWIVKNSWG
Sbjct: 246 ISVAIDAGHQSFQFYKSGIYFDPDCSSKDLDHGVLVVGYGFEGTDSNNKFWIVKNSWGPE 305
Query: 348 WGMNGYIEMSKDKNNQCGVATAASYPLV 431
WG NGY++M+KD+NN CG+ATAASYP V
Sbjct: 306 WGWNGYVKMAKDQNNHCGIATAASYPTV 333
>sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) (Cathepsin U)
Length = 334
Score = 176 bits (446), Expect = 3e-44
Identities = 84/148 (56%), Positives = 103/148 (69%), Gaps = 5/148 (3%)
Frame = +3
Query: 3 FAYIKQYG-IESEASYPYTANEGECSYNKAKVVANCTGFIDIPQNNENLLAASVATVGPI 179
F Y+K+ G ++SE SYPY A + C Y VAN TGF + E L +VATVGPI
Sbjct: 187 FQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPI 246
Query: 180 SIGIDASQASFQFYKSGIYDEPQCSSTSLDHGVLAVGYG----TTNGRNFWIVKNSWGTS 347
S+ +DA +SFQFYKSGIY EP CSS +LDHGVL VGYG +N +W+VKNSWG
Sbjct: 247 SVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPE 306
Query: 348 WGMNGYIEMSKDKNNQCGVATAASYPLV 431
WG NGY++++KDKNN CG+ATAASYP V
Sbjct: 307 WGSNGYVKIAKDKNNHCGIATAASYPNV 334
>sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precursor
Length = 323
Score = 176 bits (445), Expect = 4e-44
Identities = 80/144 (55%), Positives = 105/144 (72%), Gaps = 1/144 (0%)
Frame = +3
Query: 3 FAYIK-QYGIESEASYPYTANEGECSYNKAKVVANCTGFIDIPQNNENLLAASVATVGPI 179
F YIK GI++EA+YPY A +G C ++ V A C+G +I +E L +V +GPI
Sbjct: 180 FDYIKANNGIDTEAAYPYEARDGSCRFDSNSVAATCSGHTNIASGSETGLQQAVRDIGPI 239
Query: 180 SIGIDASQASFQFYKSGIYDEPQCSSTSLDHGVLAVGYGTTNGRNFWIVKNSWGTSWGMN 359
S+ IDA+ +SFQFY SG+Y EP CS + LDH VLAVGYG+ G++FW+VKNSW TSWG
Sbjct: 240 SVTIDAAHSSFQFYSSGVYYEPSCSPSYLDHAVLAVGYGSEGGQDFWLVKNSWATSWGDA 299
Query: 360 GYIEMSKDKNNQCGVATAASYPLV 431
GYI+MS+++NN CG+AT ASYPLV
Sbjct: 300 GYIKMSRNRNNNCGIATVASYPLV 323
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,820,899
Number of Sequences: 369166
Number of extensions: 1152264
Number of successful extensions: 3503
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3140
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3227
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 3168768640
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)