Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_006_K10 (754 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q13247|SFRS6_HUMAN Splicing factor, arginine/serine-rich... 64 4e-10 sp|P26686|SRR55_DROME Serine-arginine protein 55 (SRP55) (E... 60 5e-09 sp|Q08170|SFRS4_HUMAN Splicing factor, arginine/serine-rich... 60 8e-09 sp|Q8VE97|SFRS4_MOUSE Splicing factor, arginine/serine-rich 4 60 8e-09 sp|Q09167|SFRS5_RAT Splicing factor, arginine/serine-rich 5... 54 5e-07 sp|Q13243|SFRS5_HUMAN Splicing factor, arginine/serine-rich... 54 5e-07 sp|O35326|SFRS5_MOUSE Splicing factor, arginine/serine-rich... 45 2e-04 sp|P78814|SRP2_SCHPO Pre-mRNA splicing factor srp2 42 0.002 sp|Q9P2K5|MYEF2_HUMAN Myelin expression factor 2 (MyEF-2) (... 35 0.17 sp|Q8C854|MYEF2_MOUSE Myelin expression factor 2 (MyEF-2) (... 35 0.17
>sp|Q13247|SFRS6_HUMAN Splicing factor, arginine/serine-rich 6 (Pre-mRNA splicing factor SRP55) Length = 344 Score = 63.9 bits (154), Expect = 4e-10 Identities = 29/48 (60%), Positives = 38/48 (79%) Frame = +1 Query: 4 GEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHED 147 GEVT+ADAHK R N+GV+EF + SDMK A+DK DG E+ G N+++ ED Sbjct: 134 GEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIED 181
>sp|P26686|SRR55_DROME Serine-arginine protein 55 (SRP55) (Enhancer of deformed) (52-kDa bracketing protein) (B52 protein) Length = 376 Score = 60.5 bits (145), Expect = 5e-09 Identities = 29/48 (60%), Positives = 37/48 (77%) Frame = +1 Query: 4 GEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHED 147 GEVT+ADAHK R+N+GVVEF++ SDMK AI+K D EL G + + ED Sbjct: 144 GEVTYADAHKQRRNEGVVEFASLSDMKTAIEKLDDTELNGRRIHLVED 191
>sp|Q08170|SFRS4_HUMAN Splicing factor, arginine/serine-rich 4 (Pre-mRNA splicing factor SRP75) (SRP001LB) Length = 494 Score = 59.7 bits (143), Expect = 8e-09 Identities = 27/48 (56%), Positives = 38/48 (79%) Frame = +1 Query: 4 GEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHED 147 GEVT+ADAHK R+N+GV+EF + SDMK A++K DG E+ G +++ ED Sbjct: 128 GEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVED 175
>sp|Q8VE97|SFRS4_MOUSE Splicing factor, arginine/serine-rich 4 Length = 489 Score = 59.7 bits (143), Expect = 8e-09 Identities = 27/48 (56%), Positives = 38/48 (79%) Frame = +1 Query: 4 GEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHED 147 GEVT+ADAHK R+N+GV+EF + SDMK A++K DG E+ G +++ ED Sbjct: 128 GEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVED 175
>sp|Q09167|SFRS5_RAT Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor SRP40) (Insulin-induced growth response protein CL-4) (Delayed-early protein HRS) Length = 269 Score = 53.9 bits (128), Expect = 5e-07 Identities = 25/47 (53%), Positives = 35/47 (74%) Frame = +1 Query: 4 GEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHE 144 GEVTFADAH+ + N+GVVEF++ D+K AI+K G E+ G +K+ E Sbjct: 132 GEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE 178
>sp|Q13243|SFRS5_HUMAN Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor SRP40) (Delayed-early protein HRS) Length = 272 Score = 53.9 bits (128), Expect = 5e-07 Identities = 25/47 (53%), Positives = 35/47 (74%) Frame = +1 Query: 4 GEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHE 144 GEVTFADAH+ + N+GVVEF++ D+K AI+K G E+ G +K+ E Sbjct: 132 GEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE 178
>sp|O35326|SFRS5_MOUSE Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor SRP40) (Delayed-early protein HRS) Length = 270 Score = 45.4 bits (106), Expect = 2e-04 Identities = 20/32 (62%), Positives = 27/32 (84%) Frame = +1 Query: 4 GEVTFADAHKLRQNQGVVEFSNSSDMKAAIDK 99 GEVTFADAH+ + N+GVVEF++ D+K AI+K Sbjct: 132 GEVTFADAHRPKLNEGVVEFASYGDLKNAIEK 163
>sp|P78814|SRP2_SCHPO Pre-mRNA splicing factor srp2 Length = 365 Score = 42.0 bits (97), Expect = 0.002 Identities = 20/48 (41%), Positives = 27/48 (56%) Frame = +1 Query: 4 GEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHED 147 GE TF DAH+ GVVEFS DM+ A+ +G + G + + ED Sbjct: 122 GEPTFTDAHRENPGAGVVEFSTEEDMRNALTSLNGEVIKGQAVTLRED 169
>sp|Q9P2K5|MYEF2_HUMAN Myelin expression factor 2 (MyEF-2) (MST156) Length = 600 Score = 35.4 bits (80), Expect = 0.17 Identities = 21/53 (39%), Positives = 29/53 (54%), Gaps = 4/53 (7%) Frame = +1 Query: 1 VGEVT----FADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHED 147 VGEVT F DA + GVVEF + +K A++ + Y+L G L + ED Sbjct: 124 VGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKED 176
>sp|Q8C854|MYEF2_MOUSE Myelin expression factor 2 (MyEF-2) (MEF-2) Length = 591 Score = 35.4 bits (80), Expect = 0.17 Identities = 21/53 (39%), Positives = 29/53 (54%), Gaps = 4/53 (7%) Frame = +1 Query: 1 VGEVT----FADAHKLRQNQGVVEFSNSSDMKAAIDKYDGYELYGYNLKVHED 147 VGEVT F DA + GVVEF + +K A++ + Y+L G L + ED Sbjct: 115 VGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKED 167
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.317 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 54,487,848 Number of Sequences: 369166 Number of extensions: 809625 Number of successful extensions: 2398 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2312 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2394 length of database: 68,354,980 effective HSP length: 108 effective length of database: 48,403,600 effective search space used: 6873311200 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits)