Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_006_J09
(900 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P08574|CY1_HUMAN Cytochrome c1, heme protein, mitochondr... 319 8e-87
sp|Q9D0M3|CY1_MOUSE Cytochrome c1, heme protein, mitochondr... 317 4e-86
sp|P00125|CY1_BOVIN Cytochrome c1, heme protein, mitochondr... 311 1e-84
sp|P25076|CY11_SOLTU Cytochrome c1, heme protein, mitochond... 277 3e-74
sp|P29610|CY12_SOLTU Cytochrome c1, heme protein, mitochond... 274 2e-73
sp|P07142|CY1_NEUCR Cytochrome c1, heme protein, mitochondr... 261 2e-69
sp|P07143|CY1_YEAST Cytochrome c1, heme protein, mitochondr... 260 4e-69
sp|Q00988|CY1_KLULA Cytochrome c1, heme protein, mitochondr... 257 4e-68
sp|P20114|CY1_EUGGR Cytochrome c1, heme protein 199 7e-51
sp|P51131|CYBC_BRAJA Cytochrome b/c1 [Contains: Cytochrome ... 196 6e-50
>sp|P08574|CY1_HUMAN Cytochrome c1, heme protein, mitochondrial precursor (Cytochrome
c-1)
Length = 325
Score = 319 bits (817), Expect = 8e-87
Identities = 149/260 (57%), Positives = 191/260 (73%)
Frame = +2
Query: 59 GTVVCGAAVTTLAVSFAVTPAYASDLIAHPPSLPWYHSGLTHSYDHAAIRRGYQVYKQVC 238
G + G A +A+ AV+ ASDL HPPS PW H GL S DH +IRRG+QVYKQVC
Sbjct: 65 GMLAAGGAGLAVALHSAVS---ASDLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVC 121
Query: 239 AACHSMKFISYRHLVGVCLTEDEAKQEAAEINVLDGPNDEGLMYDRPGRLGDYFPKPYAN 418
A+CHSM F++YRHLVGVC TEDEAK+ AAE+ V DGPN++G M+ RPG+L DYFPKPY N
Sbjct: 122 ASCHSMDFVAYRHLVGVCYTEDEAKELAAEVEVQDGPNEDGEMFMRPGKLFDYFPKPYPN 181
Query: 419 DELARKANNGALPPDLSLIVKAREGGEDYIFQILTGYCDPPAGRNLDEGQYYNPYFPGGG 598
E AR ANNGALPPDLS IV+AR GGEDY+F +LTGYC+PP G +L EG Y+NPYFPG
Sbjct: 182 SEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQA 241
Query: 599 ISMAQALYDEIIEYPDGTPATTSQLAKDVVTFLTWTGDPHLEKRKKFAPRFYLTIGFLIA 778
I+MA +Y +++E+ DGTPAT SQ+AKDV TFL W +P + RK+ + + + L+
Sbjct: 242 IAMAPPIYTDVLEFDDGTPATMSQIAKDVCTFLRWASEPEHDHRKRMGLKMLMMMALLVP 301
Query: 779 IVFYIRNMKFAHLKNIKCAF 838
+V+ I+ K++ LK+ K A+
Sbjct: 302 LVYTIKRHKWSVLKSRKLAY 321
>sp|Q9D0M3|CY1_MOUSE Cytochrome c1, heme protein, mitochondrial precursor (Cytochrome
c-1)
Length = 325
Score = 317 bits (811), Expect = 4e-86
Identities = 148/260 (56%), Positives = 188/260 (72%)
Frame = +2
Query: 59 GTVVCGAAVTTLAVSFAVTPAYASDLIAHPPSLPWYHSGLTHSYDHAAIRRGYQVYKQVC 238
G + G A +A+ AV+ ASDL HPPS PW H GL S DH +IRRG+QVYKQVC
Sbjct: 65 GMLAAGGAGLAVALHSAVS---ASDLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVC 121
Query: 239 AACHSMKFISYRHLVGVCLTEDEAKQEAAEINVLDGPNDEGLMYDRPGRLGDYFPKPYAN 418
++CHSM +++YRHLVGVC TE+EAK A E+ V DGPND+G M+ RPG+L DYFPKPY N
Sbjct: 122 SSCHSMDYVAYRHLVGVCYTEEEAKALAEEVEVQDGPNDDGEMFMRPGKLSDYFPKPYPN 181
Query: 419 DELARKANNGALPPDLSLIVKAREGGEDYIFQILTGYCDPPAGRNLDEGQYYNPYFPGGG 598
E AR ANNGALPPDLS IV+AR GGEDY+F +LTGYC+PP G +L EG Y+NPYFPG
Sbjct: 182 PEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQA 241
Query: 599 ISMAQALYDEIIEYPDGTPATTSQLAKDVVTFLTWTGDPHLEKRKKFAPRFYLTIGFLIA 778
I MA +Y E++EY DGTPAT SQ+AKDV TFL W +P + RK+ + L +G L+
Sbjct: 242 IGMAPPIYTEVLEYDDGTPATMSQVAKDVATFLRWASEPEHDHRKRMGLKMLLMMGLLLP 301
Query: 779 IVFYIRNMKFAHLKNIKCAF 838
+ + ++ K++ LK+ K A+
Sbjct: 302 LTYAMKRHKWSVLKSRKLAY 321
>sp|P00125|CY1_BOVIN Cytochrome c1, heme protein, mitochondrial (Cytochrome c-1)
Length = 241
Score = 311 bits (798), Expect = 1e-84
Identities = 141/237 (59%), Positives = 179/237 (75%)
Frame = +2
Query: 128 SDLIAHPPSLPWYHSGLTHSYDHAAIRRGYQVYKQVCAACHSMKFISYRHLVGVCLTEDE 307
SDL HPPS PW H GL S DH +IRRG+QVYKQVC++CHSM +++YRHLVGVC TEDE
Sbjct: 1 SDLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVCSSCHSMDYVAYRHLVGVCYTEDE 60
Query: 308 AKQEAAEINVLDGPNDEGLMYDRPGRLGDYFPKPYANDELARKANNGALPPDLSLIVKAR 487
AK A E+ V DGPN++G M+ RPG+L DYFPKPY N E AR ANNGALPPDLS IV+AR
Sbjct: 61 AKALAEEVEVQDGPNEDGEMFMRPGKLSDYFPKPYPNPEAARAANNGALPPDLSYIVRAR 120
Query: 488 EGGEDYIFQILTGYCDPPAGRNLDEGQYYNPYFPGGGISMAQALYDEIIEYPDGTPATTS 667
GGEDY+F +LTGYC+PP G +L EG Y+NPYFPG I MA +Y+E++E+ DGTPAT S
Sbjct: 121 HGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQAIGMAPPIYNEVLEFDDGTPATMS 180
Query: 668 QLAKDVVTFLTWTGDPHLEKRKKFAPRFYLTIGFLIAIVFYIRNMKFAHLKNIKCAF 838
Q+AKDV TFL W +P + RK+ + L +G L+ +V+ ++ K++ LK+ K A+
Sbjct: 181 QVAKDVCTFLRWAAEPEHDHRKRMGLKMLLMMGLLLPLVYAMKRHKWSVLKSRKLAY 237
>sp|P25076|CY11_SOLTU Cytochrome c1, heme protein, mitochondrial precursor (Clone
PC13III)
Length = 320
Score = 277 bits (708), Expect = 3e-74
Identities = 142/270 (52%), Positives = 183/270 (67%), Gaps = 3/270 (1%)
Frame = +2
Query: 29 LKSKWTKRIGGTVVCGAAVTTLAVSFAVTPAYASDLIAHP---PSLPWYHSGLTHSYDHA 199
L S +K GA V+ L +SFA T AY SD H P+ PW H G+ SYDHA
Sbjct: 47 LGSAGSKSFRALAAIGAGVSGL-LSFA-TIAY-SDEAEHGLECPNYPWPHEGILSSYDHA 103
Query: 200 AIRRGYQVYKQVCAACHSMKFISYRHLVGVCLTEDEAKQEAAEINVLDGPNDEGLMYDRP 379
+IRRG+QVY+QVCA+CHSM ISYR LVGV TE+E K AAEI V+DGPNDEG M+ RP
Sbjct: 104 SIRRGHQVYQQVCASCHSMSLISYRDLVGVAYTEEETKAMAAEIEVVDGPNDEGEMFTRP 163
Query: 380 GRLGDYFPKPYANDELARKANNGALPPDLSLIVKAREGGEDYIFQILTGYCDPPAGRNLD 559
G+L D FP+PYAN+ AR AN GA PPDLSLI KAR G++Y+F +LT Y DPPAG ++
Sbjct: 164 GKLSDRFPQPYANEAAARFANGGAYPPDLSLITKARHNGQNYVFALLTAYRDPPAGVSIR 223
Query: 560 EGQYYNPYFPGGGISMAQALYDEIIEYPDGTPATTSQLAKDVVTFLTWTGDPHLEKRKKF 739
EG +YNPYFPGG I+M + L D +EY DG PAT +Q+ KDVV+FL+W +P +E+RK
Sbjct: 224 EGLHYNPYFPGGAIAMPKMLNDGAVEYEDGIPATEAQMGKDVVSFLSWAAEPEMEERKLM 283
Query: 740 APRFYLTIGFLIAIVFYIRNMKFAHLKNIK 829
++ + + Y R ++++ LK+ K
Sbjct: 284 GFKWIFVLSLALLQAAYYRRLRWSVLKSRK 313
>sp|P29610|CY12_SOLTU Cytochrome c1, heme protein, mitochondrial precursor (Clone PC18I)
Length = 260
Score = 274 bits (701), Expect = 2e-73
Identities = 132/252 (52%), Positives = 172/252 (68%)
Frame = +2
Query: 74 GAAVTTLAVSFAVTPAYASDLIAHPPSLPWYHSGLTHSYDHAAIRRGYQVYKQVCAACHS 253
GA V+ L V A ++ PS PW H+G+ SYDHA+IRRG+QVY+QVCA+CHS
Sbjct: 2 GAGVSGLLGFATVASADEAEHGLECPSYPWPHAGILSSYDHASIRRGHQVYQQVCASCHS 61
Query: 254 MKFISYRHLVGVCLTEDEAKQEAAEINVLDGPNDEGLMYDRPGRLGDYFPKPYANDELAR 433
M +SYR LVGV TE+E K AAEI V DGPNDEG M+ RPG+L D FP+PY N+ AR
Sbjct: 62 MSLVSYRDLVGVAYTEEEVKAMAAEIEVEDGPNDEGEMFTRPGKLSDRFPQPYPNEAAAR 121
Query: 434 KANNGALPPDLSLIVKAREGGEDYIFQILTGYCDPPAGRNLDEGQYYNPYFPGGGISMAQ 613
AN GA PPDLSLI KAR G++Y+F +LT Y DPPAG ++ EG +YNPYFPGG I+M +
Sbjct: 122 FANGGAYPPDLSLITKARHNGQNYVFALLTAYRDPPAGVSIREGLHYNPYFPGGAIAMPK 181
Query: 614 ALYDEIIEYPDGTPATTSQLAKDVVTFLTWTGDPHLEKRKKFAPRFYLTIGFLIAIVFYI 793
L D +EY DG PAT +Q+ KDVV+FLTW +P +E+RK ++ + + Y
Sbjct: 182 MLNDGAVEYEDGVPATEAQMGKDVVSFLTWAAEPEMEERKLMGFKWIFVLSLALLQAAYY 241
Query: 794 RNMKFAHLKNIK 829
R ++++ LK+ K
Sbjct: 242 RRLRWSVLKSRK 253
>sp|P07142|CY1_NEUCR Cytochrome c1, heme protein, mitochondrial precursor
Length = 332
Score = 261 bits (666), Expect = 2e-69
Identities = 137/290 (47%), Positives = 177/290 (61%), Gaps = 23/290 (7%)
Frame = +2
Query: 38 KWTKRIGGTVVCGAAVTT---LAVSFAVTPAYASDLIA-------------------HPP 151
K+ KR T GAA + L ++ A A A+ IA H
Sbjct: 22 KFAKRSASTQSSGAAAESPLRLNIAAAAATAVAAGSIAWYYHLYGFASAMTPAEEGLHAT 81
Query: 152 SLPWYHSGLTHSYDHAAIRRGYQVYKQVCAACHSMKFISYRHLVGVCLTEDEAKQEAAEI 331
PW H ++DH A+RRG+QVY++VCA+CHS+ + YR LVG LT DEAK A E
Sbjct: 82 KYPWVHEQWLKTFDHQALRRGFQVYREVCASCHSLSRVPYRALVGTILTVDEAKALAEEN 141
Query: 332 NVLDGPNDEGLMYDRPGRLGDYFPKPYANDELARKANNGALPPDLSLIVKAREGGEDYIF 511
PND+G + RPG+L DY P PY NDE AR ANNGALPPDLSLIVKAR GG DYIF
Sbjct: 142 EYDTEPNDQGEIEKRPGKLSDYLPDPYKNDEAARFANNGALPPDLSLIVKARHGGCDYIF 201
Query: 512 QILTGYCD-PPAGRNLDEGQYYNPYFPGGGISMAQALYDEIIEYPDGTPATTSQLAKDVV 688
+LTGY D PPAG ++ G +NPYFPG GI+MA+ LYD +++Y DGTPA+TSQ+AKDVV
Sbjct: 202 SLLTGYPDEPPAGASVGAGLNFNPYFPGTGIAMARVLYDGLVDYEDGTPASTSQMAKDVV 261
Query: 689 TFLTWTGDPHLEKRKKFAPRFYLTIGFLIAIVFYIRNMKFAHLKNIKCAF 838
FL W +P ++ RK+ + + L A+ Y++ K+A LK+ K +
Sbjct: 262 EFLNWAAEPEMDDRKRMGMKVLVVTSVLFALSVYVKRYKWAWLKSRKIVY 311
>sp|P07143|CY1_YEAST Cytochrome c1, heme protein, mitochondrial precursor
Length = 309
Score = 260 bits (664), Expect = 4e-69
Identities = 129/270 (47%), Positives = 174/270 (64%), Gaps = 3/270 (1%)
Frame = +2
Query: 59 GTVVCGAAVTTL--AVSFAVTPAYASDLIAHPPSLPWYHSGLTHSYDHAAIRRGYQVYKQ 232
G G +TL A S A++ H P+ W H+G ++DHA+IRRGYQVY++
Sbjct: 40 GVAAAGITASTLLYADSLTAEAMTAAEHGLHAPAYAWSHNGPFETFDHASIRRGYQVYRE 99
Query: 233 VCAACHSMKFISYRHLVGVCLTEDEAKQEAAEINVLDGPNDEGLMYDRPGRLGDYFPKPY 412
VCAACHS+ +++R LVGV T +E + A E D P+++G RPG+L DY P PY
Sbjct: 100 VCAACHSLDRVAWRTLVGVSHTNEEVRNMAEEFEYDDEPDEQGNPKKRPGKLSDYIPGPY 159
Query: 413 ANDELARKANNGALPPDLSLIVKAREGGEDYIFQILTGYCD-PPAGRNLDEGQYYNPYFP 589
N++ AR AN GALPPDLSLIVKAR GG DYIF +LTGY D PPAG L G YNPYFP
Sbjct: 160 PNEQAARAANQGALPPDLSLIVKARHGGCDYIFSLLTGYPDEPPAGVALPPGSNYNPYFP 219
Query: 590 GGGISMAQALYDEIIEYPDGTPATTSQLAKDVVTFLTWTGDPHLEKRKKFAPRFYLTIGF 769
GG I+MA+ L+D+++EY DGTPATTSQ+AKDV TFL W +P ++RK+ + + +
Sbjct: 220 GGSIAMARVLFDDMVEYEDGTPATTSQMAKDVTTFLNWCAEPEHDERKRLGLKTVIILSS 279
Query: 770 LIAIVFYIRNMKFAHLKNIKCAFTSKRYKK 859
L + +++ K+A +K K F + +K
Sbjct: 280 LYLLSIWVKKFKWAGIKTRKFVFNPPKPRK 309
>sp|Q00988|CY1_KLULA Cytochrome c1, heme protein, mitochondrial precursor
Length = 292
Score = 257 bits (656), Expect = 4e-68
Identities = 126/265 (47%), Positives = 172/265 (64%), Gaps = 3/265 (1%)
Frame = +2
Query: 53 IGGTVVCGAAVTTL--AVSFAVTPAYASDLIAHPPSLPWYHSGLTHSYDHAAIRRGYQVY 226
+GG V G +T+ A S A++ H P W H+G ++DH++IRRGYQVY
Sbjct: 23 VGGAAVVGIGASTMLYADSLTADAMTAAEHGLHAPGYGWSHNGPLETFDHSSIRRGYQVY 82
Query: 227 KQVCAACHSMKFISYRHLVGVCLTEDEAKQEAAEINVLDGPNDEGLMYDRPGRLGDYFPK 406
++VCAACHS+ +++R +VGV T E + A E D P+D+G RPG+L DY P
Sbjct: 83 REVCAACHSLDRVAWRTMVGVSHTNAEVRAMAEEFEYDDEPDDQGNPKKRPGKLADYVPG 142
Query: 407 PYANDELARKANNGALPPDLSLIVKAREGGEDYIFQILTGYC-DPPAGRNLDEGQYYNPY 583
PY N++ AR AN GALPPDLSLIVKAR GG DYIF +LTGY +PPAG L G YNPY
Sbjct: 143 PYPNEQAARAANQGALPPDLSLIVKARHGGPDYIFALLTGYPEEPPAGVVLPPGANYNPY 202
Query: 584 FPGGGISMAQALYDEIIEYPDGTPATTSQLAKDVVTFLTWTGDPHLEKRKKFAPRFYLTI 763
FPGG I+M + L+D+++EY DGTPATTSQ+AKDV TFL W +P ++RK+ + + +
Sbjct: 203 FPGGSIAMGRVLFDDLVEYEDGTPATTSQMAKDVTTFLHWCSEPEHDERKRLGLKAMIVL 262
Query: 764 GFLIAIVFYIRNMKFAHLKNIKCAF 838
L + +++ K+A +K+ K F
Sbjct: 263 SSLYLLSVWVKKFKWASIKSRKIVF 287
>sp|P20114|CY1_EUGGR Cytochrome c1, heme protein
Length = 243
Score = 199 bits (507), Expect = 7e-51
Identities = 105/241 (43%), Positives = 140/241 (58%), Gaps = 1/241 (0%)
Frame = +2
Query: 140 AHPPSLPWYHSGLTHSYDHAAIRRGYQVYKQVCAACHSMKFISYRHLVGVCLTEDEAKQE 319
+HPP+LPW H D ++RRG +VY+QV A CHS+ FI YRH ++++E K
Sbjct: 4 SHPPALPWPHFQWFQGLDWRSVRRGKEVYEQVFAPCHSLSFIKYRHFEAF-MSKEEVKNM 62
Query: 320 AAEINVLDGPNDEGLMYDRPGRLGDYFPKPYANDELARKANNGALPPDLSLIVKAREGGE 499
AA V D P+++G RPG+ D +PY N++ AR ANNGALPPDLS+I AR GG
Sbjct: 63 AASFEVDDDPDEKGEARKRPGKRFDTVVQPYKNEQEARYANNGALPPDLSVITNARHGGV 122
Query: 500 DYIFQILTGYCDP-PAGRNLDEGQYYNPYFPGGGISMAQALYDEIIEYPDGTPATTSQLA 676
DYI+ +LTGY P P G L Q+YNPYF GG I M L D++IEY DGTPA+ Q+A
Sbjct: 123 DYIYALLTGYGRPVPGGVQLSTTQWYNPYFHGGIIGMPPPLTDDMIEYEDGTPASVPQMA 182
Query: 677 KDVVTFLTWTGDPHLEKRKKFAPRFYLTIGFLIAIVFYIRNMKFAHLKNIKCAFTSKRYK 856
KDV FL W +P ++RK + T+ + Y ++ + AF Y
Sbjct: 183 KDVTCFLEWCSNPWWDERKLLGYKTIATLAVIAVSSGYYNRFLSGLWRSRRLAFRPFNYS 242
Query: 857 K 859
K
Sbjct: 243 K 243
>sp|P51131|CYBC_BRAJA Cytochrome b/c1 [Contains: Cytochrome b; Cytochrome c1]
Length = 687
Score = 196 bits (499), Expect = 6e-50
Identities = 103/278 (37%), Positives = 154/278 (55%), Gaps = 26/278 (9%)
Frame = +2
Query: 56 GGTVVCGAAVTTLAVSF----AVTPAYASDLIAHPPSLPWYHSGLTHSYDHAAIRRGYQV 223
GG V A+ +A ++ A A++ PP W +G +D A++RG +V
Sbjct: 407 GGKAVASVAIALVAAGALFLGSLQDARANEGSDKPPGNKWSFAGPFGKFDRGALQRGLKV 466
Query: 224 YKQVCAACHSMKFISYRHLV---GVCLTEDEAKQEAAEINVLDGPNDEGLMYDRPGRLGD 394
YK+VCA+CH + +I++R+L G + + A++ + DGPND G M++RPGR D
Sbjct: 467 YKEVCASCHGLSYIAFRNLAEAGGPSYSVAQVAAFASDYKIKDGPNDAGDMFERPGRPAD 526
Query: 395 YFPKPYANDELARKANNGALPPDLSLIVKAR------------------EGGEDYIFQIL 520
YFP P+ N++ AR AN GA PPDLSLI KAR E G DY+ +L
Sbjct: 527 YFPSPFPNEQAARAANGGAAPPDLSLITKARSYGRGFPWFIFDFFTQYQEQGPDYVSAVL 586
Query: 521 TGYCDP-PAGRNLDEGQYYNPYFPGGGISMAQALYDEIIEYPDGTPATTSQLAKDVVTFL 697
G+ + P G + EG YYN YFPG I M + L D + Y DG+PAT +Q +KDV TFL
Sbjct: 587 QGFEEKVPEGVTIPEGSYYNKYFPGHAIKMPKPLSDGQVTYDDGSPATVAQYSKDVTTFL 646
Query: 698 TWTGDPHLEKRKKFAPRFYLTIGFLIAIVFYIRNMKFA 811
WT +PH+E RK+ + ++ + ++++ + +A
Sbjct: 647 MWTAEPHMEARKRLGFQVFVFLIIFAGLMYFTKKKVWA 684
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 103,686,232
Number of Sequences: 369166
Number of extensions: 2255692
Number of successful extensions: 5525
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5345
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5509
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9078450570
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)