Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_006_J03
(721 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O93248|OPA1_ONCMA Dynamin-like 120 kDa protein, mitochon... 159 5e-39
sp|O60313|OPA1_HUMAN Dynamin-like 120 kDa protein, mitochon... 155 1e-37
sp|P58281|OPA1_MOUSE Dynamin-like 120 kDa protein, mitochon... 155 1e-37
sp|P13828|MSP1_PLAYO Merozoite surface protein 1 precursor ... 34 0.34
sp|Q13325|IFIT5_HUMAN Interferon-induced protein with tetra... 33 0.59
sp|P04975|CLCB_BOVIN Clathrin light chain B (Lcb) 33 0.59
sp|Q02455|MLP1_YEAST Protein MLP1 (Myosin-like protein 1) 32 1.3
sp|P09497|CLCB_HUMAN Clathrin light chain B (Lcb) 32 1.3
sp|Q8K9P5|Y275_BUCAP Hypothetical UPF0063 protein BUsg275 32 1.7
sp|Q92878|RAD50_HUMAN DNA repair protein RAD50 (hRAD50) 32 2.2
>sp|O93248|OPA1_ONCMA Dynamin-like 120 kDa protein, mitochondrial precursor (120-kDa G
protein expressed in motor neurons) (mG120)
Length = 971
Score = 159 bits (403), Expect = 5e-39
Identities = 75/197 (38%), Positives = 127/197 (64%)
Frame = +1
Query: 58 NLQGPGFVESWRKWQSRTPTQRKRCAVFDELSKILENEPSHKMSLSSDELTTIKRNLQMK 237
++ GP + + W W++R+P Q R +EL ++L+ H L++DE+TT+++NL+ +
Sbjct: 776 DMVGPDWKQRWMSWKNRSPEQHTRNETRNELERLLKLHEDHTAYLANDEVTTVRKNLEGR 835
Query: 238 KIDVDSEFIQESWMVTYKEFLFEKAKERAKDCQKGFYHYHFGFAEKADFDCRDVVFFRRV 417
++VD I+++W Y+ +KA + C++GFY+Y F + ++ +C DVV F R+
Sbjct: 836 GVEVDPALIKDTWHQLYRRHFLQKALQHCNLCRRGFYYYQRHFVD-SELECNDVVLFWRI 894
Query: 418 LRMLETSSAALRNQIMNNEMRRMESIVKSVLDEIGTNPSELKQLLSGEKVTLAENLKRVR 597
RML ++ LR Q+ N E+RR+E VK VL++ G + L++G +V LAE+LK+VR
Sbjct: 895 QRMLLITANTLRQQLTNTEVRRLEKNVKEVLEDFGEDNERKVHLITGRRVQLAEDLKKVR 954
Query: 598 QIQEKLDEFITALNKDK 648
+IQEKL+ FI AL+K+K
Sbjct: 955 EIQEKLEAFIEALHKEK 971
>sp|O60313|OPA1_HUMAN Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy
1 gene protein)
Length = 960
Score = 155 bits (392), Expect = 1e-37
Identities = 76/197 (38%), Positives = 125/197 (63%)
Frame = +1
Query: 58 NLQGPGFVESWRKWQSRTPTQRKRCAVFDELSKILENEPSHKMSLSSDELTTIKRNLQMK 237
N+ GP + + W W++RT Q +EL K+L+ H L+SDE+TT+++NL+ +
Sbjct: 765 NMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESR 824
Query: 238 KIDVDSEFIQESWMVTYKEFLFEKAKERAKDCQKGFYHYHFGFAEKADFDCRDVVFFRRV 417
++VD I+++W Y+ + A C++GFY+Y F + ++ +C DVV F R+
Sbjct: 825 GVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVD-SELECNDVVLFWRI 883
Query: 418 LRMLETSSAALRNQIMNNEMRRMESIVKSVLDEIGTNPSELKQLLSGEKVTLAENLKRVR 597
RML ++ LR Q+ N E+RR+E VK VL++ + + +LL+G++V LAE+LK+VR
Sbjct: 884 QRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVR 943
Query: 598 QIQEKLDEFITALNKDK 648
+IQEKLD FI AL+++K
Sbjct: 944 EIQEKLDAFIEALHQEK 960
>sp|P58281|OPA1_MOUSE Dynamin-like 120 kDa protein, mitochondrial precursor (Large GTP
binding protein) (LargeG)
Length = 960
Score = 155 bits (392), Expect = 1e-37
Identities = 76/197 (38%), Positives = 125/197 (63%)
Frame = +1
Query: 58 NLQGPGFVESWRKWQSRTPTQRKRCAVFDELSKILENEPSHKMSLSSDELTTIKRNLQMK 237
N+ GP + + W W++RT Q +EL K+L+ H L+SDE+TT+++NL+ +
Sbjct: 765 NMIGPDWKKRWMYWKNRTQEQCVHNETKNELEKMLKVNDEHPAYLASDEITTVRKNLESR 824
Query: 238 KIDVDSEFIQESWMVTYKEFLFEKAKERAKDCQKGFYHYHFGFAEKADFDCRDVVFFRRV 417
++VD I+++W Y+ + A C++GFY+Y F + ++ +C DVV F R+
Sbjct: 825 GVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFID-SELECNDVVLFWRI 883
Query: 418 LRMLETSSAALRNQIMNNEMRRMESIVKSVLDEIGTNPSELKQLLSGEKVTLAENLKRVR 597
RML ++ LR Q+ N E+RR+E VK VL++ + + +LL+G++V LAE+LK+VR
Sbjct: 884 QRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKVKLLTGKRVQLAEDLKKVR 943
Query: 598 QIQEKLDEFITALNKDK 648
+IQEKLD FI AL+++K
Sbjct: 944 EIQEKLDAFIEALHQEK 960
>sp|P13828|MSP1_PLAYO Merozoite surface protein 1 precursor (Merozoite surface antigens)
(PMMSA) (230 kDa) (PY230)
Length = 1772
Score = 34.3 bits (77), Expect = 0.34
Identities = 28/119 (23%), Positives = 49/119 (41%), Gaps = 23/119 (19%)
Frame = +1
Query: 361 GFAEKADFDCRDVVFFRRVLRMLETSSAALRNQIMNNE-----------------MRRME 489
G E + + FF +++ + T AA++ QI E + ++
Sbjct: 1500 GINEDIETTTDGIKFFNKMVELYNTQLAAVKEQIATIEAETNDTNKEEKKKYIPILEDLK 1559
Query: 490 SIVKSVLDEIGTNPSELKQLLSGEKVTLAE------NLKRVRQIQEKLDEFITALNKDK 648
+ ++V+ + EL+ L K AE NL++ QI EKLDEF+ +K
Sbjct: 1560 GLYETVIGQAEEYSEELQNRLDNYKNEKAEFEILTKNLEKYIQIDEKLDEFVEHAENNK 1618
>sp|Q13325|IFIT5_HUMAN Interferon-induced protein with tetratricopeptide repeats 5
(IFIT-5) (Retinoic acid- and interferon-inducible 58 kDa
protein)
Length = 482
Score = 33.5 bits (75), Expect = 0.59
Identities = 39/178 (21%), Positives = 70/178 (39%), Gaps = 14/178 (7%)
Frame = +1
Query: 145 ELSKILENEPSHKMSLSSDELTTIKRNLQMKKIDVDSEFI----------QESWMVTYKE 294
++ K N P K L DEL + ++ DS F E + E
Sbjct: 299 QIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAE 358
Query: 295 FLFEKAK--ERAKDCQKGFYHYHFGFAEKADFDCRDVVFFRRVLRMLETSSAALRNQIMN 468
+F KA E D K HYH+G ++ + + + + LR ++
Sbjct: 359 DIFRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKL-T 417
Query: 469 NEMRRMES--IVKSVLDEIGTNPSELKQLLSGEKVTLAENLKRVRQIQEKLDEFITAL 636
+ ++++ + + + LD + L GEK AE ++ ++I + EF+TAL
Sbjct: 418 SALKKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTAL 475
>sp|P04975|CLCB_BOVIN Clathrin light chain B (Lcb)
Length = 228
Score = 33.5 bits (75), Expect = 0.59
Identities = 31/127 (24%), Positives = 54/127 (42%), Gaps = 10/127 (7%)
Frame = +1
Query: 82 ESWRKWQSRTPTQRKRCAVFDELSKILENEPSHKMSLSSDELTTIKRNLQMKKIDVDSEF 261
ES RKW+ QRKR D SK++E E K +E +++ Q++K +++
Sbjct: 100 ESIRKWREE---QRKRLQELDAASKVMEQEWREKAKKDLEEWNQ-RQSEQVEKNKINNRI 155
Query: 262 IQESW----------MVTYKEFLFEKAKERAKDCQKGFYHYHFGFAEKADFDCRDVVFFR 411
+++ V +E +++KE + F K+ C+DV R
Sbjct: 156 ADKAFYQQPDADIIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLR 215
Query: 412 RVLRMLE 432
VL L+
Sbjct: 216 SVLMSLK 222
>sp|Q02455|MLP1_YEAST Protein MLP1 (Myosin-like protein 1)
Length = 1875
Score = 32.3 bits (72), Expect = 1.3
Identities = 17/66 (25%), Positives = 39/66 (59%)
Frame = +1
Query: 418 LRMLETSSAALRNQIMNNEMRRMESIVKSVLDEIGTNPSELKQLLSGEKVTLAENLKRVR 597
L +L S+ LRN++ NN ++ E ++S LD++ N + ++ L+ K ++ E + ++
Sbjct: 1216 LNLLRESNITLRNELENNNNKKKE--LQSELDKLKQNVAPIESELTALKYSMQEKEQELK 1273
Query: 598 QIQEKL 615
+E++
Sbjct: 1274 LAKEEV 1279
>sp|P09497|CLCB_HUMAN Clathrin light chain B (Lcb)
Length = 229
Score = 32.3 bits (72), Expect = 1.3
Identities = 31/127 (24%), Positives = 53/127 (41%), Gaps = 10/127 (7%)
Frame = +1
Query: 82 ESWRKWQSRTPTQRKRCAVFDELSKILENEPSHKMSLSSDELTTIKRNLQMKKIDVDSEF 261
ES RKW+ QRKR D SK+ E E K +E +++ Q++K +++
Sbjct: 101 ESIRKWREE---QRKRLQELDAASKVTEQEWREKAKKDLEEWNQ-RQSEQVEKNKINNRI 156
Query: 262 IQESW----------MVTYKEFLFEKAKERAKDCQKGFYHYHFGFAEKADFDCRDVVFFR 411
+++ V +E +++KE + F K+ C+DV R
Sbjct: 157 ADKAFYQQPDADIIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLR 216
Query: 412 RVLRMLE 432
VL L+
Sbjct: 217 SVLMSLK 223
>sp|Q8K9P5|Y275_BUCAP Hypothetical UPF0063 protein BUsg275
Length = 363
Score = 32.0 bits (71), Expect = 1.7
Identities = 43/184 (23%), Positives = 72/184 (39%), Gaps = 15/184 (8%)
Frame = +1
Query: 136 VFDELSKILENEPSHKMSLSSDELTTIKRNLQMKKIDVDSEFIQE--------SWMVTYK 291
V D+L K + N + +L S+ I++ L + S FI+E W+ +
Sbjct: 38 VTDQLMKWIYNRHCNNFNLMSNLKKDIRKKLNERSYIFASNFIEEKISYDGTVKWITSID 97
Query: 292 ----EFLFEKAKERAKDCQKGFYHYHFGFAEKADFDCRDVVFFRRVLRMLETSSAALRNQ 459
E ++ K+RA C G + K F F R L++ E S +
Sbjct: 98 KQKIETIYIPEKKRATLCVSS----QIGCSLKCKFCATGQQGFNRNLKVSEIISQIWQAN 153
Query: 460 IMNNEMRRMESIVKSVLDEIGTNPSELKQLLSGEKVTLAEN---LKRVRQIQEKLDEFIT 630
+ E + +I V +G L ++S K+ L +N L + R+I +
Sbjct: 154 KILKEKKNNSTITNIVFMGMGEPLLNLNNVISAIKIILDKNGFGLSK-RRITLSTSGIVP 212
Query: 631 ALNK 642
ALNK
Sbjct: 213 ALNK 216
>sp|Q92878|RAD50_HUMAN DNA repair protein RAD50 (hRAD50)
Length = 1312
Score = 31.6 bits (70), Expect = 2.2
Identities = 17/84 (20%), Positives = 42/84 (50%)
Frame = +1
Query: 370 EKADFDCRDVVFFRRVLRMLETSSAALRNQIMNNEMRRMESIVKSVLDEIGTNPSELKQL 549
E+ F R + F +++R + A NQ+M N+ E++ + +DEI + L ++
Sbjct: 384 ERGPFSERQIKNFHKLVRERQEGEAKTANQLM-NDFAEKETLKQKQIDEIRDKKTGLGRI 442
Query: 550 LSGEKVTLAENLKRVRQIQEKLDE 621
+ + L++ ++ ++ +L +
Sbjct: 443 IELKSEILSKKQNELKNVKYELQQ 466
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,168,455
Number of Sequences: 369166
Number of extensions: 1514119
Number of successful extensions: 4591
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4445
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4587
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6413660220
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)