Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_006_J01
(872 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8WXA9|SFR12_HUMAN Splicing factor, arginine/serine-rich... 45 3e-04
sp|Q8BZX4|SFR12_MOUSE Splicing factor, arginine/serine-rich... 42 0.002
sp|Q9JKL7|SFR12_RAT Splicing factor, arginine/serine-rich 1... 42 0.003
sp|Q9U7E0|ATRX_CAEEL Transcriptional regulator ATRX homolog... 42 0.003
sp|P29973|CNGA1_HUMAN cGMP-gated cation channel alpha 1 (CN... 40 0.006
sp|Q8CST4|IF2_STAES Translation initiation factor IF-2 >gi|... 40 0.006
sp|P09346|KNOB_PLAFG Knob-associated histidine-rich protein... 40 0.011
sp|P40467|YIN0_YEAST Putative 108.8 kDa transcriptional reg... 40 0.011
sp|P05229|KNOB_PLAFD Knob-associated histidine-rich protein... 40 0.011
sp|P13817|KNOB_PLAFA Knob-associated histidine-rich protein... 40 0.011
>sp|Q8WXA9|SFR12_HUMAN Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich
splicing regulatory protein 86) (SRrp86) (Splicing
regulatory protein 508) (SRrp508)
Length = 508
Score = 45.1 bits (105), Expect = 3e-04
Identities = 31/102 (30%), Positives = 49/102 (48%), Gaps = 6/102 (5%)
Frame = +1
Query: 16 SRYKSNNKRDRSSNHYYQPSNHGNYNHNRKKNDMKDNEDYERPSKKNSYEK-RKPVKQDN 192
S KS+++R RS S H + +HNR ++ KD + P KK S + R+ + +
Sbjct: 202 SSSKSHSRRKRSQ------SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRS 255
Query: 193 DEGDSRMDNKKPAEIKRESKNPDKTPEPE-----QAEKERGQ 303
D R D ++ + K K D+ E E + EKERG+
Sbjct: 256 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK 297
>sp|Q8BZX4|SFR12_MOUSE Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich
splicing regulatory protein 86) (SRrp86)
Length = 494
Score = 42.4 bits (98), Expect = 0.002
Identities = 29/100 (29%), Positives = 50/100 (50%), Gaps = 4/100 (4%)
Frame = +1
Query: 16 SRYKSNNKRDRSSNHYYQPSNHGNYNHNRKKNDMKDNEDYERPSKKNSYEK-RKPVKQDN 192
S KS+++R RS S H + +HNR ++ KD + P KK S + R+ + +
Sbjct: 205 SSSKSHSRRKRSQ------SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRS 258
Query: 193 DEGDSRMDNKKPAEIKRESKNPDKTPEPE---QAEKERGQ 303
D R D ++ + + + K +K E E + +KERG+
Sbjct: 259 RSRDKRKDTREKVKERVKEKEREKEREREKDREKDKERGK 298
>sp|Q9JKL7|SFR12_RAT Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich
splicing regulatory protein 86) (SRrp86) (SR-related
protein of 86 kDa)
Length = 494
Score = 41.6 bits (96), Expect = 0.003
Identities = 29/100 (29%), Positives = 50/100 (50%), Gaps = 4/100 (4%)
Frame = +1
Query: 16 SRYKSNNKRDRSSNHYYQPSNHGNYNHNRKKNDMKDNEDYERPSKKNSYEK-RKPVKQDN 192
S KS+++R RS S H + +HNR ++ KD + P KK S + R+ + +
Sbjct: 205 SSSKSHSRRKRSQ------SKHRSRSHNRSRSRQKDRARSKSPHKKRSKSRERRKSRSRS 258
Query: 193 DEGDSRMDNKKPAE--IKRESKNPDKTPEPE-QAEKERGQ 303
D R D ++ + +K + +K E E + +KERG+
Sbjct: 259 RSRDKRKDTREKVKERVKEREREKEKEREKEREKDKERGK 298
Score = 34.3 bits (77), Expect = 0.46
Identities = 22/98 (22%), Positives = 43/98 (43%), Gaps = 3/98 (3%)
Frame = +1
Query: 10 RTSRYKSNNKRDRSSNHYYQPSNHGNYNHNRKKNDMKDNEDYERPSKKNSYEKRKPVKQD 189
R R +S+++ R+S + S+ R K + K ++ + S + E+ K+
Sbjct: 367 RRRRSRSSSRSPRTSKTIKRKSSRSPSPRGRNKKEKKREKERDHISDRRERERSTSTKKS 426
Query: 190 NDEGDSRMDNKK---PAEIKRESKNPDKTPEPEQAEKE 294
+ + D + +K P + K SK D T + EK+
Sbjct: 427 SSDRDGKEKVEKTNTPVKEKEHSKEADSTVSTDADEKD 464
Score = 32.7 bits (73), Expect = 1.4
Identities = 25/103 (24%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Frame = +1
Query: 1 NKYRTSRYKSNNKRDRSSNHYYQPSNHGNYNHNRKKNDMKDNEDYERPSKKNSYEKRKPV 180
+K+R+ + N R R + S H + +R++ + + R +K++ EK K
Sbjct: 218 SKHRSRSH--NRSRSRQKDRARSKSPHKKRSKSRERRKSR-SRSRSRDKRKDTREKVKER 274
Query: 181 KQDNDEGDSRMDNKKPAEIKRESKNPDKTPEPEQ-AEKERGQK 306
++ + + K+ + K KN DK E E+ EKER ++
Sbjct: 275 VKEREREKEKEREKEREKDKERGKNKDKDREKEKDHEKERDKE 317
>sp|Q9U7E0|ATRX_CAEEL Transcriptional regulator ATRX homolog (X-linked nuclear protein 1)
Length = 1359
Score = 41.6 bits (96), Expect = 0.003
Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 16/113 (14%)
Frame = +1
Query: 16 SRYKSNNKRDRSSNHYYQPSNHGNYNHNRKKNDMK----------DNEDYERPSKKNSYE 165
S+ KS + ++S+ + S KKN K ++++ E+PSKK+
Sbjct: 140 SKKKSKKTKKQTSSESSEESEEERKVKKSKKNKEKSVKKRAETSEESDEDEKPSKKSKKG 199
Query: 166 KRKPVKQDN-----DEGDSRMDNKKPAEI-KRESKNPDKTPEPEQAEKERGQK 306
+K K ++ DE + + KK ++ K+ES++ D+ PE ++ EK + K
Sbjct: 200 LKKKAKSESESESEDEKEVKKSKKKSKKVVKKESESEDEAPEKKKTEKRKRSK 252
Score = 36.2 bits (82), Expect = 0.12
Identities = 27/105 (25%), Positives = 44/105 (41%), Gaps = 11/105 (10%)
Frame = +1
Query: 25 KSNNKRDRSSNHYYQPSNHGNYNHNRKKNDMKDNEDYERPSKKNSYEKRKPVKQDN--DE 198
K KR+R P + + +D++D E +K+S + RK K ++ DE
Sbjct: 38 KLKEKREREGK---PPPKKRPAKKRKASSSEEDDDDEEESPRKSSKKSRKRAKSESESDE 94
Query: 199 GDSRMDNKKPAEIKR---------ESKNPDKTPEPEQAEKERGQK 306
D D KK K+ + K + E E +++ER QK
Sbjct: 95 SDEEEDRKKSKSKKKVDQKKKEKSKKKRTTSSSEDEDSDEEREQK 139
Score = 30.4 bits (67), Expect = 6.7
Identities = 16/95 (16%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
Frame = +1
Query: 25 KSNNKRDRSSNHYYQPSNHGNYNHNRKKNDMKDNEDYERPSKKNSYEKRKPVK-QDNDEG 201
+S+ + DR + + + ++KK +ED + ++ K+K K +
Sbjct: 94 ESDEEEDRKKSKSKKKVDQKKKEKSKKKRTTSSSEDEDSDEEREQKSKKKSKKTKKQTSS 153
Query: 202 DSRMDNKKPAEIKRESKNPDKTPEPEQAEKERGQK 306
+S ++++ ++K+ KN +K+ + E +
Sbjct: 154 ESSEESEEERKVKKSKKNKEKSVKKRAETSEESDE 188
>sp|P29973|CNGA1_HUMAN cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1)
(CNG1) (Cyclic nucleotide gated channel alpha 1) (Cyclic
nucleotide gated channel, photoreceptor)
(Cyclic-nucleotide-gated cation channel 1) (Rod
photoreceptor cGMP-gated channel alpha subunit)
Length = 686
Score = 40.4 bits (93), Expect = 0.006
Identities = 26/91 (28%), Positives = 42/91 (46%)
Frame = +1
Query: 22 YKSNNKRDRSSNHYYQPSNHGNYNHNRKKNDMKDNEDYERPSKKNSYEKRKPVKQDNDEG 201
YKS K S Y P +N N N KD E E+ KK +++K D +E
Sbjct: 64 YKSLRKGGPSQREQYLPGAIALFNVNNSSN--KDQEPEEKKKKK---KEKKSKSDDKNEN 118
Query: 202 DSRMDNKKPAEIKRESKNPDKTPEPEQAEKE 294
+ + KK + K + K +K+ + ++ EK+
Sbjct: 119 KNDPEKKKKKKDKEKKKKEEKSKDKKEEEKK 149
>sp|Q8CST4|IF2_STAES Translation initiation factor IF-2
sp|Q5HPS2|IF2_STAEQ Translation initiation factor IF-2
Length = 720
Score = 40.4 bits (93), Expect = 0.006
Identities = 26/99 (26%), Positives = 53/99 (53%), Gaps = 2/99 (2%)
Frame = +1
Query: 4 KYRTSRYKSNNKRDRSSNHYYQPSNHGNYNHNRKKNDMKDNEDYERPSKKNSYEKRKPVK 183
K++ S+ K NK++ +NH Q SN+ +++++K K+N +P+KK K
Sbjct: 49 KFKASQAKDTNKQNTQNNH--QKSNNKQNSNDKEKQQSKNN---SKPTKK---------K 94
Query: 184 QDNDEGDSRMDNKKPAEIKRESKNP--DKTPEPEQAEKE 294
+ N++G + N K + ++ +KN +K +P+ +E
Sbjct: 95 EQNNKGKQQNKNNKTNKNQKNNKNKKNNKNNKPQNEVEE 133
Score = 31.2 bits (69), Expect = 3.9
Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 2/90 (2%)
Frame = +1
Query: 1 NKYRT--SRYKSNNKRDRSSNHYYQPSNHGNYNHNRKKNDMKDNEDYERPSKKNSYEKRK 174
NK T + KSNNK++ + Q N N +KK + + +K N +K
Sbjct: 59 NKQNTQNNHQKSNNKQNSNDKEKQQSKN--NSKPTKKKEQNNKGKQQNKNNKTNKNQKNN 116
Query: 175 PVKQDNDEGDSRMDNKKPAEIKRESKNPDK 264
K++N +NK E++ + P K
Sbjct: 117 KNKKNN------KNNKPQNEVEETKEMPSK 140
>sp|P09346|KNOB_PLAFG Knob-associated histidine-rich protein precursor (KAHRP) (KP)
Length = 634
Score = 39.7 bits (91), Expect = 0.011
Identities = 31/112 (27%), Positives = 50/112 (44%), Gaps = 10/112 (8%)
Frame = +1
Query: 10 RTSRYKSNNKRDRSSN--HYYQPSNHGNYNHNRKKNDMKDNEDYERPSKKNSYEKRKPVK 183
R S + S NK + + H+ + GN KK K ++D++ KK+ K
Sbjct: 342 RYSSFSSVNKYGKHGDEKHHSSKKHEGNDGEGEKKKKSKKHKDHDGEKKKSKKHK----- 396
Query: 184 QDNDEGDSRMDNKKPAEIKRESKNPDKTPEPEQAE--------KERGQKYQG 315
DN++ +S + +KK E K K + E AE KE+G+K+ G
Sbjct: 397 -DNEDAES-VKSKKHKSHDCEKKKSKKHKDNEDAESVKSKKSVKEKGEKHNG 446
>sp|P40467|YIN0_YEAST Putative 108.8 kDa transcriptional regulatory protein in FKH1-STH1
intergenic region
Length = 964
Score = 39.7 bits (91), Expect = 0.011
Identities = 22/87 (25%), Positives = 38/87 (43%)
Frame = +1
Query: 1 NKYRTSRYKSNNKRDRSSNHYYQPSNHGNYNHNRKKNDMKDNEDYERPSKKNSYEKRKPV 180
N + +NN + ++N +N+ N N+N+ ND D PS + + + P+
Sbjct: 851 NDNNNNNNNNNNNNNNNNNSGNSSNNNNNNNNNKNNNDFGIKIDNNSPSYEGFPQLQIPL 910
Query: 181 KQDNDEGDSRMDNKKPAEIKRESKNPD 261
QDN + + + EIK E D
Sbjct: 911 SQDNLNIEDKEEMSPNIEIKNEQNMTD 937
Score = 35.8 bits (81), Expect = 0.16
Identities = 16/77 (20%), Positives = 35/77 (45%)
Frame = +1
Query: 1 NKYRTSRYKSNNKRDRSSNHYYQPSNHGNYNHNRKKNDMKDNEDYERPSKKNSYEKRKPV 180
N Y K+NN + ++N +N+ N N+N N+ +N + ++
Sbjct: 823 NNYNNVSGKNNNNNNITNNSNNNHNNNNNDNNNNNNNNNNNNNNNNNSGNSSNNNNNNNN 882
Query: 181 KQDNDEGDSRMDNKKPA 231
++N++ ++DN P+
Sbjct: 883 NKNNNDFGIKIDNNSPS 899
Score = 32.7 bits (73), Expect = 1.4
Identities = 20/96 (20%), Positives = 39/96 (40%), Gaps = 10/96 (10%)
Frame = +1
Query: 16 SRYKSNNKRDRSSNHYYQPS----------NHGNYNHNRKKNDMKDNEDYERPSKKNSYE 165
S +N+ D +N+Y S N+ N NHN ND +N + + N+
Sbjct: 810 SNASNNSNPDTINNNYNNVSGKNNNNNNITNNSNNNHNNNNNDNNNNNNNNNNNNNNNNN 869
Query: 166 KRKPVKQDNDEGDSRMDNKKPAEIKRESKNPDKTPE 273
+N+ +++ +N +I S + + P+
Sbjct: 870 SGNSSNNNNNNNNNKNNNDFGIKIDNNSPSYEGFPQ 905
>sp|P05229|KNOB_PLAFD Knob-associated histidine-rich protein (KAHRP)
Length = 277
Score = 39.7 bits (91), Expect = 0.011
Identities = 31/112 (27%), Positives = 50/112 (44%), Gaps = 10/112 (8%)
Frame = +1
Query: 10 RTSRYKSNNKRDRSSN--HYYQPSNHGNYNHNRKKNDMKDNEDYERPSKKNSYEKRKPVK 183
R S + S NK + + H+ + GN KK K ++D++ KK+ K
Sbjct: 157 RYSSFSSVNKYGKHGDEKHHSSKKHEGNDGEGEKKKKSKKHKDHDGEKKKSKKHK----- 211
Query: 184 QDNDEGDSRMDNKKPAEIKRESKNPDKTPEPEQAE--------KERGQKYQG 315
DN++ +S + +KK E K K + E AE KE+G+K+ G
Sbjct: 212 -DNEDAES-VKSKKHKSHDCEKKKSKKHKDNEDAESVKSKKSVKEKGEKHNG 261
>sp|P13817|KNOB_PLAFA Knob-associated histidine-rich protein precursor (KAHRP) (HRPI)
Length = 473
Score = 39.7 bits (91), Expect = 0.011
Identities = 31/112 (27%), Positives = 50/112 (44%), Gaps = 10/112 (8%)
Frame = +1
Query: 10 RTSRYKSNNKRDRSSN--HYYQPSNHGNYNHNRKKNDMKDNEDYERPSKKNSYEKRKPVK 183
R S + S NK + + H+ + GN KK K ++D++ KK+ K
Sbjct: 342 RYSSFSSVNKYGKHGDEKHHSSKKHEGNDGEGEKKKKSKKHKDHDGEKKKSKKHK----- 396
Query: 184 QDNDEGDSRMDNKKPAEIKRESKNPDKTPEPEQAE--------KERGQKYQG 315
DN++ +S + +KK E K K + E AE KE+G+K+ G
Sbjct: 397 -DNEDAES-VKSKKHKSHDCEKKKSKKHKDNEDAESVKSKKSVKEKGEKHNG 446
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.304 0.124 0.360
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,691,375
Number of Sequences: 369166
Number of extensions: 598463
Number of successful extensions: 3673
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2615
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3309
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8646143400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)