Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_006_I13 (976 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P54823|DDX6_MOUSE Probable ATP-dependent RNA helicase DD... 380 e-105 sp|P54824|DDX6_XENLA Probable ATP-dependent RNA helicase DD... 380 e-105 sp|P26196|DDX6_HUMAN Probable ATP-dependent RNA helicase DD... 379 e-105 sp|P23128|ME31_DROME Putative ATP-dependent RNA helicase me... 373 e-103 sp|P39517|DHH1_YEAST Putative ATP-dependent RNA helicase DHH1 342 7e-94 sp|Q09181|STE13_SCHPO Putative ATP-dependent RNA helicase s... 334 2e-91 sp|P27639|IF4A_CAEEL Eukaryotic initiation factor 4A (eIF4A... 188 2e-47 sp|O02494|IF4A_CRYPV Eukaryotic initiation factor 4A (eIF4A... 187 3e-47 sp|P47943|IF4A_SCHPO Eukaryotic initiation factor 4A (eIF4A... 187 4e-47 sp|Q25225|IF4A_LEIBR Probable eukaryotic initiation factor ... 186 7e-47
>sp|P54823|DDX6_MOUSE Probable ATP-dependent RNA helicase DDX6 (DEAD-box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog) Length = 483 Score = 380 bits (976), Expect = e-105 Identities = 184/248 (74%), Positives = 215/248 (86%) Frame = +3 Query: 15 ARGNFCKILVIDEADKLLSADFEEVIDYIISKLPTQRQIMLYSATFPQSVQQFLEKHMRD 194 A+ + +++V+DEADKLLS DF ++++ II LP RQI+LYSATFP SVQ+F+ H++ Sbjct: 235 AKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQK 294 Query: 195 PYEINLMDELTLKGISQYYAYVQERQKVHCLNTLFSRLQINQSIIFCNTAQRVELLAKKI 374 PYEINLM+ELTLKG++QYYAYV ERQKVHCLNTLFSRLQINQSIIFCN++QRVELLAKKI Sbjct: 295 PYEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKI 354 Query: 375 TDLGYSCYYIHAKMNQVYRNRVFHEFRNGNCRNLVCTDLFTRGIDIPSVNVVINFDFPKY 554 + LGYSC+YIHAKM Q +RNRVFH+FRNG CRNLVCTDLFTRGIDI +VNVVINFDFPK Sbjct: 355 SQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKL 414 Query: 555 AETYLHRIGRSGRYGHLGVAVNLITYDDRFALKNIETQLNTEIKAIPKYIDKRLYVAEYQ 734 AETYLHRIGRSGR+GHLG+A+NLITYDDRF LK+IE QL TEIK IP IDK LYVAEY Sbjct: 415 AETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYH 474 Query: 735 NENELDTR 758 +E D + Sbjct: 475 SEPAEDEK 482
>sp|P54824|DDX6_XENLA Probable ATP-dependent RNA helicase DDX6 (DEAD-box protein 6) (ATP-dependent RNA helicase p54) (Xp54) Length = 481 Score = 380 bits (976), Expect = e-105 Identities = 184/246 (74%), Positives = 215/246 (87%) Frame = +3 Query: 15 ARGNFCKILVIDEADKLLSADFEEVIDYIISKLPTQRQIMLYSATFPQSVQQFLEKHMRD 194 A+ + +++V+DEADKLLS DF ++++ II LP RQI+LYSATFP SVQ+F+ H++ Sbjct: 234 AKVDHIQMIVLDEADKLLSQDFMQIMEDIIMTLPKNRQILLYSATFPLSVQKFMTLHLQK 293 Query: 195 PYEINLMDELTLKGISQYYAYVQERQKVHCLNTLFSRLQINQSIIFCNTAQRVELLAKKI 374 PYEINLM+ELTLKG++QYYAYV ERQKVHCLNTLFSRLQINQSIIFCN++QRVELLAKKI Sbjct: 294 PYEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKI 353 Query: 375 TDLGYSCYYIHAKMNQVYRNRVFHEFRNGNCRNLVCTDLFTRGIDIPSVNVVINFDFPKY 554 + LGYSC+YIHAKM Q +RNRVFH+FRNG CRNLVCTDLFTRGIDI +VNVVINFDFPK Sbjct: 354 SQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKL 413 Query: 555 AETYLHRIGRSGRYGHLGVAVNLITYDDRFALKNIETQLNTEIKAIPKYIDKRLYVAEYQ 734 AETYLHRIGRSGR+GHLG+A+NLITYDDRF LK+IE QL TEIK IP IDK LYVAEY Sbjct: 414 AETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSSIDKNLYVAEYH 473 Query: 735 NENELD 752 +E+ D Sbjct: 474 SESGED 479
>sp|P26196|DDX6_HUMAN Probable ATP-dependent RNA helicase DDX6 (DEAD-box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK) Length = 483 Score = 379 bits (974), Expect = e-105 Identities = 183/242 (75%), Positives = 212/242 (87%) Frame = +3 Query: 15 ARGNFCKILVIDEADKLLSADFEEVIDYIISKLPTQRQIMLYSATFPQSVQQFLEKHMRD 194 A+ + +++V+DEADKLLS DF ++++ II LP RQI+LYSATFP SVQ+F+ H+ Sbjct: 235 AKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLEK 294 Query: 195 PYEINLMDELTLKGISQYYAYVQERQKVHCLNTLFSRLQINQSIIFCNTAQRVELLAKKI 374 PYEINLM+ELTLKG++QYYAYV ERQKVHCLNTLFSRLQINQSIIFCN++QRVELLAKKI Sbjct: 295 PYEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKI 354 Query: 375 TDLGYSCYYIHAKMNQVYRNRVFHEFRNGNCRNLVCTDLFTRGIDIPSVNVVINFDFPKY 554 + LGYSC+YIHAKM Q +RNRVFH+FRNG CRNLVCTDLFTRGIDI +VNVVINFDFPK Sbjct: 355 SQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKL 414 Query: 555 AETYLHRIGRSGRYGHLGVAVNLITYDDRFALKNIETQLNTEIKAIPKYIDKRLYVAEYQ 734 AETYLHRIGRSGR+GHLG+A+NLITYDDRF LK+IE QL TEIK IP IDK LYVAEY Sbjct: 415 AETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYH 474 Query: 735 NE 740 +E Sbjct: 475 SE 476
>sp|P23128|ME31_DROME Putative ATP-dependent RNA helicase me31b (Maternal expression at 31B) Length = 459 Score = 373 bits (958), Expect = e-103 Identities = 175/232 (75%), Positives = 207/232 (89%) Frame = +3 Query: 30 CKILVIDEADKLLSADFEEVIDYIISKLPTQRQIMLYSATFPQSVQQFLEKHMRDPYEIN 209 C+ILV+DEADKLLS DF+ ++D++I KLP QI+L+SATFP +V+ F+EKH+R+PYEIN Sbjct: 201 CRILVLDEADKLLSLDFQGMLDHVILKLPKDPQILLFSATFPLTVKNFMEKHLREPYEIN 260 Query: 210 LMDELTLKGISQYYAYVQERQKVHCLNTLFSRLQINQSIIFCNTAQRVELLAKKITDLGY 389 LM+ELTLKG++QYYA+VQERQKVHCLNTLFS+LQINQSIIFCN+ QRVELLAKKIT+LGY Sbjct: 261 LMEELTLKGVTQYYAFVQERQKVHCLNTLFSKLQINQSIIFCNSTQRVELLAKKITELGY 320 Query: 390 SCYYIHAKMNQVYRNRVFHEFRNGNCRNLVCTDLFTRGIDIPSVNVVINFDFPKYAETYL 569 CYYIHAKM Q +RNRVFH+FR G CRNLVC+DLFTRGID+ +VNVVINFDFP+ AETYL Sbjct: 321 CCYYIHAKMAQAHRNRVFHDFRQGLCRNLVCSDLFTRGIDVQAVNVVINFDFPRMAETYL 380 Query: 570 HRIGRSGRYGHLGVAVNLITYDDRFALKNIETQLNTEIKAIPKYIDKRLYVA 725 HRIGRSGR+GHLG+A+NLITY+DRF L IE +L TEIK IPK ID LYVA Sbjct: 381 HRIGRSGRFGHLGIAINLITYEDRFDLHRIEKELGTEIKPIPKVIDPALYVA 432
>sp|P39517|DHH1_YEAST Putative ATP-dependent RNA helicase DHH1 Length = 506 Score = 342 bits (878), Expect = 7e-94 Identities = 163/233 (69%), Positives = 196/233 (84%) Frame = +3 Query: 30 CKILVIDEADKLLSADFEEVIDYIISKLPTQRQIMLYSATFPQSVQQFLEKHMRDPYEIN 209 C + ++DEADK+LS DF+ +I+ I+S LP Q +L+SATFP +V++F+ KH+ PYEIN Sbjct: 189 CSLFIMDEADKMLSRDFKTIIEQILSFLPPTHQSLLFSATFPLTVKEFMVKHLHKPYEIN 248 Query: 210 LMDELTLKGISQYYAYVQERQKVHCLNTLFSRLQINQSIIFCNTAQRVELLAKKITDLGY 389 LM+ELTLKGI+QYYA+V+ERQK+HCLNTLFS+LQINQ+IIFCN+ RVELLAKKITDLGY Sbjct: 249 LMEELTLKGITQYYAFVEERQKLHCLNTLFSKLQINQAIIFCNSTNRVELLAKKITDLGY 308 Query: 390 SCYYIHAKMNQVYRNRVFHEFRNGNCRNLVCTDLFTRGIDIPSVNVVINFDFPKYAETYL 569 SCYY HA+M Q RN+VFHEFR G R LVC+DL TRGIDI +VNVVINFDFPK AETYL Sbjct: 309 SCYYSHARMKQQERNKVFHEFRQGKVRTLVCSDLLTRGIDIQAVNVVINFDFPKTAETYL 368 Query: 570 HRIGRSGRYGHLGVAVNLITYDDRFALKNIETQLNTEIKAIPKYIDKRLYVAE 728 HRIGRSGR+GHLG+A+NLI ++DRF L IE +L TEI AIP IDK LYVAE Sbjct: 369 HRIGRSGRFGHLGLAINLINWNDRFNLYKIEQELGTEIAAIPATIDKSLYVAE 421
>sp|Q09181|STE13_SCHPO Putative ATP-dependent RNA helicase ste13 Length = 485 Score = 334 bits (857), Expect = 2e-91 Identities = 165/252 (65%), Positives = 195/252 (77%), Gaps = 3/252 (1%) Frame = +3 Query: 30 CKILVIDEADKLLSADFEEVIDYIISKLPTQRQIMLYSATFPQSVQQFLEKHMRDPYEIN 209 C V+DEADKLLS +F +I+ ++S P RQI LYSATFP V+ F++KH+ PYEIN Sbjct: 187 CTTFVMDEADKLLSPEFTPIIEQLLSYFPKNRQISLYSATFPLIVKNFMDKHLNKPYEIN 246 Query: 210 LMDELTLKGISQYYAYVQERQKVHCLNTLFSRLQINQSIIFCNTAQRVELLAKKITDLGY 389 LMDELTL+G++QYYA+V E QKVHCLNTLFS+LQINQSIIFCN+ RVELLAKKIT+LGY Sbjct: 247 LMDELTLRGVTQYYAFVDESQKVHCLNTLFSKLQINQSIIFCNSTNRVELLAKKITELGY 306 Query: 390 SCYYIHAKMNQVYRNRVFHEFRNGNCRNLVCTDLFTRGIDIPSVNVVINFDFPKYAETYL 569 SC+Y HAKM Q +RNRVFH FRNG CRNLVC+DL TRGIDI +VNVVINFDFPK AETYL Sbjct: 307 SCFYSHAKMLQSHRNRVFHNFRNGVCRNLVCSDLLTRGIDIQAVNVVINFDFPKNAETYL 366 Query: 570 HRIGRSGRYGHLGVAVNLITYDDRFALKNIETQLNTEIKAIPKYIDKRLYV---AEYQNE 740 HRIGRSGR+GH G+A++ I++ DRF L IE +L TEI+ IP ID LYV +YQ Sbjct: 367 HRIGRSGRFGHRGLAISFISWADRFNLYRIENELGTEIQPIPPSIDPSLYVFPNGDYQIP 426 Query: 741 NELDTRIRDALA 776 L LA Sbjct: 427 RPLTASADQVLA 438
>sp|P27639|IF4A_CAEEL Eukaryotic initiation factor 4A (eIF4A) (eIF-4A) Length = 402 Score = 188 bits (477), Expect = 2e-47 Identities = 94/226 (41%), Positives = 147/226 (65%), Gaps = 2/226 (0%) Frame = +3 Query: 33 KILVIDEADKLLSADFEEVIDYIISKLPTQRQIMLYSATFPQSVQQFLEKHMRDPYEINL 212 K+ V+DEAD++LS F++ I + +P Q++L SAT P V + MR+P I + Sbjct: 173 KMFVLDEADEMLSRGFKDQIYEVFRSMPQDVQVVLLSATMPSEVLDVTNRFMRNPIRILV 232 Query: 213 M-DELTLKGISQYYAYVQERQ-KVHCLNTLFSRLQINQSIIFCNTAQRVELLAKKITDLG 386 DELTL+GI Q+Y VQ+ + K CL L++ + + Q++IFCNT ++V+ L +K+T+ Sbjct: 233 KKDELTLEGIRQFYINVQKDEWKFDCLCDLYNVVNVTQAVIFCNTRRKVDTLTEKMTENQ 292 Query: 387 YSCYYIHAKMNQVYRNRVFHEFRNGNCRNLVCTDLFTRGIDIPSVNVVINFDFPKYAETY 566 ++ +H M+Q R+ + EFR+G+ R L+ TD+ RGID+ V++VIN+D P E Y Sbjct: 293 FTVSCLHGDMDQAERDTIMREFRSGSSRVLITTDILARGIDVQQVSLVINYDLPSNRENY 352 Query: 567 LHRIGRSGRYGHLGVAVNLITYDDRFALKNIETQLNTEIKAIPKYI 704 +HRIGRSGR+G GVA+N +T +D LK IE+ T+I+ +P+ I Sbjct: 353 IHRIGRSGRFGRKGVAINFVTENDARQLKEIESYYTTQIEEMPESI 398
>sp|O02494|IF4A_CRYPV Eukaryotic initiation factor 4A (eIF4A) (eIF-4A) Length = 405 Score = 187 bits (476), Expect = 3e-47 Identities = 96/223 (43%), Positives = 145/223 (65%), Gaps = 2/223 (0%) Frame = +3 Query: 33 KILVIDEADKLLSADFEEVIDYIISKLPTQRQIMLYSATFPQSVQQFLEKHMRDPYEINL 212 K+ ++DEAD++LS F+ I I KLP Q+ L+SAT P + + MRDP I + Sbjct: 175 KLFILDEADEMLSRGFKVQIHDIFKKLPQDVQVALFSATMPNEILHLTTQFMRDPKRILV 234 Query: 213 -MDELTLKGISQYYAYVQERQ-KVHCLNTLFSRLQINQSIIFCNTAQRVELLAKKITDLG 386 +ELTL+GI Q+Y V++ + K+ L L+ L I Q+II+CNT +RV+ L K++ + Sbjct: 235 KQEELTLEGIRQFYVGVEKDEWKMDTLIDLYETLTIVQAIIYCNTRRRVDQLTKQMRERD 294 Query: 387 YSCYYIHAKMNQVYRNRVFHEFRNGNCRNLVCTDLFTRGIDIPSVNVVINFDFPKYAETY 566 ++C +H M+Q R + +FR+G+ R L+ TDL RGID+ V++VIN+D P ETY Sbjct: 295 FTCSSMHGDMDQKDREVIMRQFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPVSPETY 354 Query: 567 LHRIGRSGRYGHLGVAVNLITYDDRFALKNIETQLNTEIKAIP 695 +HRIGRSGR+G GV++N +T DD L++IE NT+I+ +P Sbjct: 355 IHRIGRSGRFGKKGVSINFVTDDDIVCLRDIERHYNTQIEEMP 397
>sp|P47943|IF4A_SCHPO Eukaryotic initiation factor 4A (eIF4A) (eIF-4A) Length = 392 Score = 187 bits (475), Expect = 4e-47 Identities = 95/226 (42%), Positives = 145/226 (64%), Gaps = 2/226 (0%) Frame = +3 Query: 33 KILVIDEADKLLSADFEEVIDYIISKLPTQRQIMLYSATFPQSVQQFLEKHMRDPYEINL 212 ++ V+DEAD++LS F++ I I LP Q++L SAT PQ V + K MRDP I + Sbjct: 163 QMFVLDEADEMLSRGFKDQIYDIFQLLPPTAQVVLLSATMPQDVLEVTTKFMRDPIRILV 222 Query: 213 M-DELTLKGISQYYAYVQERQ-KVHCLNTLFSRLQINQSIIFCNTAQRVELLAKKITDLG 386 DELTL+GI Q+Y V++ + K+ L L+ + + Q++IFCNT ++V+ L +++T+ Sbjct: 223 KKDELTLEGIKQFYVAVEKEEWKLDTLCDLYETVTVTQAVIFCNTRRKVDWLTEQLTERD 282 Query: 387 YSCYYIHAKMNQVYRNRVFHEFRNGNCRNLVCTDLFTRGIDIPSVNVVINFDFPKYAETY 566 ++ +H M+Q R+ + HEFR G+ R L+ TDL RGID+ V++VIN+D P E Y Sbjct: 283 FTVSSMHGDMDQAQRDTLMHEFRTGSSRILITTDLLARGIDVQQVSLVINYDLPANRENY 342 Query: 567 LHRIGRSGRYGHLGVAVNLITYDDRFALKNIETQLNTEIKAIPKYI 704 +HRIGR GR+G GV++N +T DD ++ IE NT I+ +P I Sbjct: 343 IHRIGRGGRFGRKGVSINFVTNDDVRMMREIEQFYNTHIEEMPMNI 388
>sp|Q25225|IF4A_LEIBR Probable eukaryotic initiation factor 4A (eIF4A) (eIF-4A) Length = 403 Score = 186 bits (473), Expect = 7e-47 Identities = 102/233 (43%), Positives = 145/233 (62%), Gaps = 1/233 (0%) Frame = +3 Query: 33 KILVIDEADKLLSADFEEVIDYIISKLPTQRQIMLYSATFPQSVQQFLEKHMRDPYEINL 212 ++LV+DEAD++LS F + I I LP Q+ L+SAT P+ V + +K MRDP I + Sbjct: 173 RVLVLDEADEMLSQGFADQIYEIFRFLPKDIQVALFSATMPEEVLELTKKFMRDPVRILV 232 Query: 213 MDE-LTLKGISQYYAYVQERQKVHCLNTLFSRLQINQSIIFCNTAQRVELLAKKITDLGY 389 E LTL+GI Q++ V+E K+ L L+ + I QS+IF NT ++V+ +A+K+ + Sbjct: 233 KRESLTLEGIKQFFIAVEEEHKLDTLMDLYETVSIAQSVIFANTRRKVDWIAEKLNQSNH 292 Query: 390 SCYYIHAKMNQVYRNRVFHEFRNGNCRNLVCTDLFTRGIDIPSVNVVINFDFPKYAETYL 569 + +HA+M + R RV + FR+G+ R LV TDL RGID+ VN+VINFD P E YL Sbjct: 293 TVSSMHAEMPKSDRERVMNTFRSGSSRVLVTTDLVARGIDVHHVNIVINFDLPTNKENYL 352 Query: 570 HRIGRSGRYGHLGVAVNLITYDDRFALKNIETQLNTEIKAIPKYIDKRLYVAE 728 HRIGR GRYG GVA+N +T D L IE +T+I +P +D Y+ E Sbjct: 353 HRIGRGGRYGVKGVAINFVTEKDVELLHEIEGHYHTQIDELP--VDFAAYLGE 403
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 108,598,899 Number of Sequences: 369166 Number of extensions: 2206581 Number of successful extensions: 6606 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5993 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6305 length of database: 68,354,980 effective HSP length: 111 effective length of database: 47,849,395 effective search space used: 10191921135 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)