Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_006_I13
(976 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P54823|DDX6_MOUSE Probable ATP-dependent RNA helicase DD... 380 e-105
sp|P54824|DDX6_XENLA Probable ATP-dependent RNA helicase DD... 380 e-105
sp|P26196|DDX6_HUMAN Probable ATP-dependent RNA helicase DD... 379 e-105
sp|P23128|ME31_DROME Putative ATP-dependent RNA helicase me... 373 e-103
sp|P39517|DHH1_YEAST Putative ATP-dependent RNA helicase DHH1 342 7e-94
sp|Q09181|STE13_SCHPO Putative ATP-dependent RNA helicase s... 334 2e-91
sp|P27639|IF4A_CAEEL Eukaryotic initiation factor 4A (eIF4A... 188 2e-47
sp|O02494|IF4A_CRYPV Eukaryotic initiation factor 4A (eIF4A... 187 3e-47
sp|P47943|IF4A_SCHPO Eukaryotic initiation factor 4A (eIF4A... 187 4e-47
sp|Q25225|IF4A_LEIBR Probable eukaryotic initiation factor ... 186 7e-47
>sp|P54823|DDX6_MOUSE Probable ATP-dependent RNA helicase DDX6 (DEAD-box protein 6)
(ATP-dependent RNA helicase p54) (Oncogene RCK homolog)
Length = 483
Score = 380 bits (976), Expect = e-105
Identities = 184/248 (74%), Positives = 215/248 (86%)
Frame = +3
Query: 15 ARGNFCKILVIDEADKLLSADFEEVIDYIISKLPTQRQIMLYSATFPQSVQQFLEKHMRD 194
A+ + +++V+DEADKLLS DF ++++ II LP RQI+LYSATFP SVQ+F+ H++
Sbjct: 235 AKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQK 294
Query: 195 PYEINLMDELTLKGISQYYAYVQERQKVHCLNTLFSRLQINQSIIFCNTAQRVELLAKKI 374
PYEINLM+ELTLKG++QYYAYV ERQKVHCLNTLFSRLQINQSIIFCN++QRVELLAKKI
Sbjct: 295 PYEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKI 354
Query: 375 TDLGYSCYYIHAKMNQVYRNRVFHEFRNGNCRNLVCTDLFTRGIDIPSVNVVINFDFPKY 554
+ LGYSC+YIHAKM Q +RNRVFH+FRNG CRNLVCTDLFTRGIDI +VNVVINFDFPK
Sbjct: 355 SQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKL 414
Query: 555 AETYLHRIGRSGRYGHLGVAVNLITYDDRFALKNIETQLNTEIKAIPKYIDKRLYVAEYQ 734
AETYLHRIGRSGR+GHLG+A+NLITYDDRF LK+IE QL TEIK IP IDK LYVAEY
Sbjct: 415 AETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYH 474
Query: 735 NENELDTR 758
+E D +
Sbjct: 475 SEPAEDEK 482
>sp|P54824|DDX6_XENLA Probable ATP-dependent RNA helicase DDX6 (DEAD-box protein 6)
(ATP-dependent RNA helicase p54) (Xp54)
Length = 481
Score = 380 bits (976), Expect = e-105
Identities = 184/246 (74%), Positives = 215/246 (87%)
Frame = +3
Query: 15 ARGNFCKILVIDEADKLLSADFEEVIDYIISKLPTQRQIMLYSATFPQSVQQFLEKHMRD 194
A+ + +++V+DEADKLLS DF ++++ II LP RQI+LYSATFP SVQ+F+ H++
Sbjct: 234 AKVDHIQMIVLDEADKLLSQDFMQIMEDIIMTLPKNRQILLYSATFPLSVQKFMTLHLQK 293
Query: 195 PYEINLMDELTLKGISQYYAYVQERQKVHCLNTLFSRLQINQSIIFCNTAQRVELLAKKI 374
PYEINLM+ELTLKG++QYYAYV ERQKVHCLNTLFSRLQINQSIIFCN++QRVELLAKKI
Sbjct: 294 PYEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKI 353
Query: 375 TDLGYSCYYIHAKMNQVYRNRVFHEFRNGNCRNLVCTDLFTRGIDIPSVNVVINFDFPKY 554
+ LGYSC+YIHAKM Q +RNRVFH+FRNG CRNLVCTDLFTRGIDI +VNVVINFDFPK
Sbjct: 354 SQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKL 413
Query: 555 AETYLHRIGRSGRYGHLGVAVNLITYDDRFALKNIETQLNTEIKAIPKYIDKRLYVAEYQ 734
AETYLHRIGRSGR+GHLG+A+NLITYDDRF LK+IE QL TEIK IP IDK LYVAEY
Sbjct: 414 AETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSSIDKNLYVAEYH 473
Query: 735 NENELD 752
+E+ D
Sbjct: 474 SESGED 479
>sp|P26196|DDX6_HUMAN Probable ATP-dependent RNA helicase DDX6 (DEAD-box protein 6)
(ATP-dependent RNA helicase p54) (Oncogene RCK)
Length = 483
Score = 379 bits (974), Expect = e-105
Identities = 183/242 (75%), Positives = 212/242 (87%)
Frame = +3
Query: 15 ARGNFCKILVIDEADKLLSADFEEVIDYIISKLPTQRQIMLYSATFPQSVQQFLEKHMRD 194
A+ + +++V+DEADKLLS DF ++++ II LP RQI+LYSATFP SVQ+F+ H+
Sbjct: 235 AKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLEK 294
Query: 195 PYEINLMDELTLKGISQYYAYVQERQKVHCLNTLFSRLQINQSIIFCNTAQRVELLAKKI 374
PYEINLM+ELTLKG++QYYAYV ERQKVHCLNTLFSRLQINQSIIFCN++QRVELLAKKI
Sbjct: 295 PYEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKI 354
Query: 375 TDLGYSCYYIHAKMNQVYRNRVFHEFRNGNCRNLVCTDLFTRGIDIPSVNVVINFDFPKY 554
+ LGYSC+YIHAKM Q +RNRVFH+FRNG CRNLVCTDLFTRGIDI +VNVVINFDFPK
Sbjct: 355 SQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKL 414
Query: 555 AETYLHRIGRSGRYGHLGVAVNLITYDDRFALKNIETQLNTEIKAIPKYIDKRLYVAEYQ 734
AETYLHRIGRSGR+GHLG+A+NLITYDDRF LK+IE QL TEIK IP IDK LYVAEY
Sbjct: 415 AETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYH 474
Query: 735 NE 740
+E
Sbjct: 475 SE 476
>sp|P23128|ME31_DROME Putative ATP-dependent RNA helicase me31b (Maternal expression at
31B)
Length = 459
Score = 373 bits (958), Expect = e-103
Identities = 175/232 (75%), Positives = 207/232 (89%)
Frame = +3
Query: 30 CKILVIDEADKLLSADFEEVIDYIISKLPTQRQIMLYSATFPQSVQQFLEKHMRDPYEIN 209
C+ILV+DEADKLLS DF+ ++D++I KLP QI+L+SATFP +V+ F+EKH+R+PYEIN
Sbjct: 201 CRILVLDEADKLLSLDFQGMLDHVILKLPKDPQILLFSATFPLTVKNFMEKHLREPYEIN 260
Query: 210 LMDELTLKGISQYYAYVQERQKVHCLNTLFSRLQINQSIIFCNTAQRVELLAKKITDLGY 389
LM+ELTLKG++QYYA+VQERQKVHCLNTLFS+LQINQSIIFCN+ QRVELLAKKIT+LGY
Sbjct: 261 LMEELTLKGVTQYYAFVQERQKVHCLNTLFSKLQINQSIIFCNSTQRVELLAKKITELGY 320
Query: 390 SCYYIHAKMNQVYRNRVFHEFRNGNCRNLVCTDLFTRGIDIPSVNVVINFDFPKYAETYL 569
CYYIHAKM Q +RNRVFH+FR G CRNLVC+DLFTRGID+ +VNVVINFDFP+ AETYL
Sbjct: 321 CCYYIHAKMAQAHRNRVFHDFRQGLCRNLVCSDLFTRGIDVQAVNVVINFDFPRMAETYL 380
Query: 570 HRIGRSGRYGHLGVAVNLITYDDRFALKNIETQLNTEIKAIPKYIDKRLYVA 725
HRIGRSGR+GHLG+A+NLITY+DRF L IE +L TEIK IPK ID LYVA
Sbjct: 381 HRIGRSGRFGHLGIAINLITYEDRFDLHRIEKELGTEIKPIPKVIDPALYVA 432
>sp|P39517|DHH1_YEAST Putative ATP-dependent RNA helicase DHH1
Length = 506
Score = 342 bits (878), Expect = 7e-94
Identities = 163/233 (69%), Positives = 196/233 (84%)
Frame = +3
Query: 30 CKILVIDEADKLLSADFEEVIDYIISKLPTQRQIMLYSATFPQSVQQFLEKHMRDPYEIN 209
C + ++DEADK+LS DF+ +I+ I+S LP Q +L+SATFP +V++F+ KH+ PYEIN
Sbjct: 189 CSLFIMDEADKMLSRDFKTIIEQILSFLPPTHQSLLFSATFPLTVKEFMVKHLHKPYEIN 248
Query: 210 LMDELTLKGISQYYAYVQERQKVHCLNTLFSRLQINQSIIFCNTAQRVELLAKKITDLGY 389
LM+ELTLKGI+QYYA+V+ERQK+HCLNTLFS+LQINQ+IIFCN+ RVELLAKKITDLGY
Sbjct: 249 LMEELTLKGITQYYAFVEERQKLHCLNTLFSKLQINQAIIFCNSTNRVELLAKKITDLGY 308
Query: 390 SCYYIHAKMNQVYRNRVFHEFRNGNCRNLVCTDLFTRGIDIPSVNVVINFDFPKYAETYL 569
SCYY HA+M Q RN+VFHEFR G R LVC+DL TRGIDI +VNVVINFDFPK AETYL
Sbjct: 309 SCYYSHARMKQQERNKVFHEFRQGKVRTLVCSDLLTRGIDIQAVNVVINFDFPKTAETYL 368
Query: 570 HRIGRSGRYGHLGVAVNLITYDDRFALKNIETQLNTEIKAIPKYIDKRLYVAE 728
HRIGRSGR+GHLG+A+NLI ++DRF L IE +L TEI AIP IDK LYVAE
Sbjct: 369 HRIGRSGRFGHLGLAINLINWNDRFNLYKIEQELGTEIAAIPATIDKSLYVAE 421
>sp|Q09181|STE13_SCHPO Putative ATP-dependent RNA helicase ste13
Length = 485
Score = 334 bits (857), Expect = 2e-91
Identities = 165/252 (65%), Positives = 195/252 (77%), Gaps = 3/252 (1%)
Frame = +3
Query: 30 CKILVIDEADKLLSADFEEVIDYIISKLPTQRQIMLYSATFPQSVQQFLEKHMRDPYEIN 209
C V+DEADKLLS +F +I+ ++S P RQI LYSATFP V+ F++KH+ PYEIN
Sbjct: 187 CTTFVMDEADKLLSPEFTPIIEQLLSYFPKNRQISLYSATFPLIVKNFMDKHLNKPYEIN 246
Query: 210 LMDELTLKGISQYYAYVQERQKVHCLNTLFSRLQINQSIIFCNTAQRVELLAKKITDLGY 389
LMDELTL+G++QYYA+V E QKVHCLNTLFS+LQINQSIIFCN+ RVELLAKKIT+LGY
Sbjct: 247 LMDELTLRGVTQYYAFVDESQKVHCLNTLFSKLQINQSIIFCNSTNRVELLAKKITELGY 306
Query: 390 SCYYIHAKMNQVYRNRVFHEFRNGNCRNLVCTDLFTRGIDIPSVNVVINFDFPKYAETYL 569
SC+Y HAKM Q +RNRVFH FRNG CRNLVC+DL TRGIDI +VNVVINFDFPK AETYL
Sbjct: 307 SCFYSHAKMLQSHRNRVFHNFRNGVCRNLVCSDLLTRGIDIQAVNVVINFDFPKNAETYL 366
Query: 570 HRIGRSGRYGHLGVAVNLITYDDRFALKNIETQLNTEIKAIPKYIDKRLYV---AEYQNE 740
HRIGRSGR+GH G+A++ I++ DRF L IE +L TEI+ IP ID LYV +YQ
Sbjct: 367 HRIGRSGRFGHRGLAISFISWADRFNLYRIENELGTEIQPIPPSIDPSLYVFPNGDYQIP 426
Query: 741 NELDTRIRDALA 776
L LA
Sbjct: 427 RPLTASADQVLA 438
>sp|P27639|IF4A_CAEEL Eukaryotic initiation factor 4A (eIF4A) (eIF-4A)
Length = 402
Score = 188 bits (477), Expect = 2e-47
Identities = 94/226 (41%), Positives = 147/226 (65%), Gaps = 2/226 (0%)
Frame = +3
Query: 33 KILVIDEADKLLSADFEEVIDYIISKLPTQRQIMLYSATFPQSVQQFLEKHMRDPYEINL 212
K+ V+DEAD++LS F++ I + +P Q++L SAT P V + MR+P I +
Sbjct: 173 KMFVLDEADEMLSRGFKDQIYEVFRSMPQDVQVVLLSATMPSEVLDVTNRFMRNPIRILV 232
Query: 213 M-DELTLKGISQYYAYVQERQ-KVHCLNTLFSRLQINQSIIFCNTAQRVELLAKKITDLG 386
DELTL+GI Q+Y VQ+ + K CL L++ + + Q++IFCNT ++V+ L +K+T+
Sbjct: 233 KKDELTLEGIRQFYINVQKDEWKFDCLCDLYNVVNVTQAVIFCNTRRKVDTLTEKMTENQ 292
Query: 387 YSCYYIHAKMNQVYRNRVFHEFRNGNCRNLVCTDLFTRGIDIPSVNVVINFDFPKYAETY 566
++ +H M+Q R+ + EFR+G+ R L+ TD+ RGID+ V++VIN+D P E Y
Sbjct: 293 FTVSCLHGDMDQAERDTIMREFRSGSSRVLITTDILARGIDVQQVSLVINYDLPSNRENY 352
Query: 567 LHRIGRSGRYGHLGVAVNLITYDDRFALKNIETQLNTEIKAIPKYI 704
+HRIGRSGR+G GVA+N +T +D LK IE+ T+I+ +P+ I
Sbjct: 353 IHRIGRSGRFGRKGVAINFVTENDARQLKEIESYYTTQIEEMPESI 398
>sp|O02494|IF4A_CRYPV Eukaryotic initiation factor 4A (eIF4A) (eIF-4A)
Length = 405
Score = 187 bits (476), Expect = 3e-47
Identities = 96/223 (43%), Positives = 145/223 (65%), Gaps = 2/223 (0%)
Frame = +3
Query: 33 KILVIDEADKLLSADFEEVIDYIISKLPTQRQIMLYSATFPQSVQQFLEKHMRDPYEINL 212
K+ ++DEAD++LS F+ I I KLP Q+ L+SAT P + + MRDP I +
Sbjct: 175 KLFILDEADEMLSRGFKVQIHDIFKKLPQDVQVALFSATMPNEILHLTTQFMRDPKRILV 234
Query: 213 -MDELTLKGISQYYAYVQERQ-KVHCLNTLFSRLQINQSIIFCNTAQRVELLAKKITDLG 386
+ELTL+GI Q+Y V++ + K+ L L+ L I Q+II+CNT +RV+ L K++ +
Sbjct: 235 KQEELTLEGIRQFYVGVEKDEWKMDTLIDLYETLTIVQAIIYCNTRRRVDQLTKQMRERD 294
Query: 387 YSCYYIHAKMNQVYRNRVFHEFRNGNCRNLVCTDLFTRGIDIPSVNVVINFDFPKYAETY 566
++C +H M+Q R + +FR+G+ R L+ TDL RGID+ V++VIN+D P ETY
Sbjct: 295 FTCSSMHGDMDQKDREVIMRQFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPVSPETY 354
Query: 567 LHRIGRSGRYGHLGVAVNLITYDDRFALKNIETQLNTEIKAIP 695
+HRIGRSGR+G GV++N +T DD L++IE NT+I+ +P
Sbjct: 355 IHRIGRSGRFGKKGVSINFVTDDDIVCLRDIERHYNTQIEEMP 397
>sp|P47943|IF4A_SCHPO Eukaryotic initiation factor 4A (eIF4A) (eIF-4A)
Length = 392
Score = 187 bits (475), Expect = 4e-47
Identities = 95/226 (42%), Positives = 145/226 (64%), Gaps = 2/226 (0%)
Frame = +3
Query: 33 KILVIDEADKLLSADFEEVIDYIISKLPTQRQIMLYSATFPQSVQQFLEKHMRDPYEINL 212
++ V+DEAD++LS F++ I I LP Q++L SAT PQ V + K MRDP I +
Sbjct: 163 QMFVLDEADEMLSRGFKDQIYDIFQLLPPTAQVVLLSATMPQDVLEVTTKFMRDPIRILV 222
Query: 213 M-DELTLKGISQYYAYVQERQ-KVHCLNTLFSRLQINQSIIFCNTAQRVELLAKKITDLG 386
DELTL+GI Q+Y V++ + K+ L L+ + + Q++IFCNT ++V+ L +++T+
Sbjct: 223 KKDELTLEGIKQFYVAVEKEEWKLDTLCDLYETVTVTQAVIFCNTRRKVDWLTEQLTERD 282
Query: 387 YSCYYIHAKMNQVYRNRVFHEFRNGNCRNLVCTDLFTRGIDIPSVNVVINFDFPKYAETY 566
++ +H M+Q R+ + HEFR G+ R L+ TDL RGID+ V++VIN+D P E Y
Sbjct: 283 FTVSSMHGDMDQAQRDTLMHEFRTGSSRILITTDLLARGIDVQQVSLVINYDLPANRENY 342
Query: 567 LHRIGRSGRYGHLGVAVNLITYDDRFALKNIETQLNTEIKAIPKYI 704
+HRIGR GR+G GV++N +T DD ++ IE NT I+ +P I
Sbjct: 343 IHRIGRGGRFGRKGVSINFVTNDDVRMMREIEQFYNTHIEEMPMNI 388
>sp|Q25225|IF4A_LEIBR Probable eukaryotic initiation factor 4A (eIF4A) (eIF-4A)
Length = 403
Score = 186 bits (473), Expect = 7e-47
Identities = 102/233 (43%), Positives = 145/233 (62%), Gaps = 1/233 (0%)
Frame = +3
Query: 33 KILVIDEADKLLSADFEEVIDYIISKLPTQRQIMLYSATFPQSVQQFLEKHMRDPYEINL 212
++LV+DEAD++LS F + I I LP Q+ L+SAT P+ V + +K MRDP I +
Sbjct: 173 RVLVLDEADEMLSQGFADQIYEIFRFLPKDIQVALFSATMPEEVLELTKKFMRDPVRILV 232
Query: 213 MDE-LTLKGISQYYAYVQERQKVHCLNTLFSRLQINQSIIFCNTAQRVELLAKKITDLGY 389
E LTL+GI Q++ V+E K+ L L+ + I QS+IF NT ++V+ +A+K+ +
Sbjct: 233 KRESLTLEGIKQFFIAVEEEHKLDTLMDLYETVSIAQSVIFANTRRKVDWIAEKLNQSNH 292
Query: 390 SCYYIHAKMNQVYRNRVFHEFRNGNCRNLVCTDLFTRGIDIPSVNVVINFDFPKYAETYL 569
+ +HA+M + R RV + FR+G+ R LV TDL RGID+ VN+VINFD P E YL
Sbjct: 293 TVSSMHAEMPKSDRERVMNTFRSGSSRVLVTTDLVARGIDVHHVNIVINFDLPTNKENYL 352
Query: 570 HRIGRSGRYGHLGVAVNLITYDDRFALKNIETQLNTEIKAIPKYIDKRLYVAE 728
HRIGR GRYG GVA+N +T D L IE +T+I +P +D Y+ E
Sbjct: 353 HRIGRGGRYGVKGVAINFVTEKDVELLHEIEGHYHTQIDELP--VDFAAYLGE 403
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 108,598,899
Number of Sequences: 369166
Number of extensions: 2206581
Number of successful extensions: 6606
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5993
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6305
length of database: 68,354,980
effective HSP length: 111
effective length of database: 47,849,395
effective search space used: 10191921135
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)