Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_006_H24
(433 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) ... 134 1e-31
sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathe... 133 1e-31
sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Catheps... 132 3e-31
sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precu... 132 3e-31
sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L hea... 130 1e-30
sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathe... 129 2e-30
sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted ... 129 3e-30
sp|P25784|CYSP3_HOMAM Digestive cysteine proteinase 3 precu... 129 3e-30
sp|P06797|CATL_MOUSE Cathepsin L precursor (Major excreted ... 128 4e-30
sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted pr... 127 8e-30
>sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) (Cathepsin U)
Length = 334
Score = 134 bits (336), Expect = 1e-31
Identities = 66/111 (59%), Positives = 79/111 (71%), Gaps = 5/111 (4%)
Frame = +3
Query: 3 GFQNINSCNEKDLAVAVATVGPISVAIDVGYS-FQQYKQGVYYEAKCDPTIQNHAVLVVG 179
GF + EK L AVATVGPISVA+D G+S FQ YK G+Y+E C +H VLVVG
Sbjct: 224 GFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVG 283
Query: 180 YGVE----NGHKYWLVKNSWGPSWGMNGYIKMSKDRDNNCGIATTASFPIV 320
YG E N KYWLVKNSWGP WG NGY+K++KD++N+CGIAT AS+P V
Sbjct: 284 YGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
>sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 334
Score = 133 bits (335), Expect = 1e-31
Identities = 67/111 (60%), Positives = 81/111 (72%), Gaps = 5/111 (4%)
Frame = +3
Query: 3 GFQNINSCNEKDLAVAVATVGPISVAIDVGY-SFQQYKQGVYYEAKCDPTIQNHAVLVVG 179
GF +I EK L AVATVGPISVAID G+ SFQ YK G+YY+ C +H VLVVG
Sbjct: 225 GFVDIPQ-REKALMKAVATVGPISVAIDAGHTSFQFYKSGIYYDPDCSCKDLDHGVLVVG 283
Query: 180 YGVE----NGHKYWLVKNSWGPSWGMNGYIKMSKDRDNNCGIATTASFPIV 320
YG E N +K+W+VKNSWGP WG NGY+KM+KD++N+CGIAT AS+P V
Sbjct: 284 YGFEGTDSNNNKFWIVKNSWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV 334
>sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 334
Score = 132 bits (332), Expect = 3e-31
Identities = 66/111 (59%), Positives = 80/111 (72%), Gaps = 5/111 (4%)
Frame = +3
Query: 3 GFQNINSCNEKDLAVAVATVGPISVAIDVGYS-FQQYKQGVYYEAKCDPTIQNHAVLVVG 179
GF +I EK L AVATVGPISVAID G+S FQ YK G+YY+ C +H VLVVG
Sbjct: 225 GFVDIPQ-REKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVG 283
Query: 180 YGVE----NGHKYWLVKNSWGPSWGMNGYIKMSKDRDNNCGIATTASFPIV 320
YG E N K+W+VKNSWGP WG NGY+KM+KD++N+CGI+T AS+P V
Sbjct: 284 YGFEGTDSNSSKFWIVKNSWGPEWGWNGYVKMAKDQNNHCGISTAASYPTV 334
>sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precursor
Length = 323
Score = 132 bits (332), Expect = 3e-31
Identities = 64/107 (59%), Positives = 75/107 (70%), Gaps = 1/107 (0%)
Frame = +3
Query: 3 GFQNINSCNEKDLAVAVATVGPISVAIDVGYS-FQQYKQGVYYEAKCDPTIQNHAVLVVG 179
G NI S +E L AV +GPISV ID +S FQ Y GVYYE C P+ +HAVL VG
Sbjct: 217 GHTNIASGSETGLQQAVRDIGPISVTIDAAHSSFQFYSSGVYYEPSCSPSYLDHAVLAVG 276
Query: 180 YGVENGHKYWLVKNSWGPSWGMNGYIKMSKDRDNNCGIATTASFPIV 320
YG E G +WLVKNSW SWG GYIKMS++R+NNCGIAT AS+P+V
Sbjct: 277 YGSEGGQDFWLVKNSWATSWGDAGYIKMSRNRNNNCGIATVASYPLV 323
>sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L heavy chain; Cathepsin L light
chain]
Length = 217
Score = 130 bits (327), Expect = 1e-30
Identities = 65/108 (60%), Positives = 79/108 (73%), Gaps = 2/108 (1%)
Frame = +3
Query: 3 GFQNINSCNEKDLAVAVATVGPISVAIDVGYS-FQQYKQGVYYEAKCDPTIQNHAVLVVG 179
GF +I EK L AVATVGPISVAID G+S FQ YK G+YY+ C +H VLVVG
Sbjct: 111 GFVDIPQ-REKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVG 169
Query: 180 YGVEN-GHKYWLVKNSWGPSWGMNGYIKMSKDRDNNCGIATTASFPIV 320
YG E +K+W+VKNSWGP WG GY+KM+KD++N+CGIAT AS+P V
Sbjct: 170 YGFEGTNNKFWIVKNSWGPEWGNKGYVKMAKDQNNHCGIATAASYPTV 217
>sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 333
Score = 129 bits (325), Expect = 2e-30
Identities = 61/101 (60%), Positives = 77/101 (76%), Gaps = 4/101 (3%)
Frame = +3
Query: 30 EKDLAVAVATVGPISVAIDVGY-SFQQYKQGVYYEAKCDPTIQNHAVLVVGYGVE---NG 197
EK L AVAT+GPISVAID G+ SFQ YK G+Y++ C +H VLVVGYG E +
Sbjct: 233 EKALMKAVATLGPISVAIDAGHQSFQFYKSGIYFDPDCSSKDLDHGVLVVGYGFEGTDSN 292
Query: 198 HKYWLVKNSWGPSWGMNGYIKMSKDRDNNCGIATTASFPIV 320
+K+W+VKNSWGP WG NGY+KM+KD++N+CGIAT AS+P V
Sbjct: 293 NKFWIVKNSWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV 333
>sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted protein) (MEP) [Contains:
Cathepsin L heavy chain; Cathepsin L light chain]
Length = 333
Score = 129 bits (323), Expect = 3e-30
Identities = 66/111 (59%), Positives = 79/111 (71%), Gaps = 5/111 (4%)
Frame = +3
Query: 3 GFQNINSCNEKDLAVAVATVGPISVAIDVGY-SFQQYKQGVYYEAKCDPTIQNHAVLVVG 179
GF +I EK L AVATVGPISVAID G+ SF YK+G+Y+E C +H VLVVG
Sbjct: 224 GFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVG 282
Query: 180 YGVEN----GHKYWLVKNSWGPSWGMNGYIKMSKDRDNNCGIATTASFPIV 320
YG E+ +KYWLVKNSWG WGM GY+KM+KDR N+CGIA+ AS+P V
Sbjct: 283 YGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
>sp|P25784|CYSP3_HOMAM Digestive cysteine proteinase 3 precursor
Length = 321
Score = 129 bits (323), Expect = 3e-30
Identities = 62/98 (63%), Positives = 71/98 (72%), Gaps = 1/98 (1%)
Frame = +3
Query: 30 EKDLAVAVATVGPISVAIDVG-YSFQQYKQGVYYEAKCDPTIQNHAVLVVGYGVENGHKY 206
E+ L AV+ VGPISVAID +SFQ Y GVYYE C PT +H VL VGYG E+ Y
Sbjct: 224 EEALQEAVSGVGPISVAIDASHFSFQFYSSGVYYEQNCSPTFLDHGVLAVGYGTESTKDY 283
Query: 207 WLVKNSWGPSWGMNGYIKMSKDRDNNCGIATTASFPIV 320
WLVKNSWG SWG GYIKMS++RDNNCGIA+ S+P V
Sbjct: 284 WLVKNSWGSSWGDAGYIKMSRNRDNNCGIASEPSYPTV 321
>sp|P06797|CATL_MOUSE Cathepsin L precursor (Major excreted protein) (MEP) (p39 cysteine
proteinase) [Contains: Cathepsin L heavy chain;
Cathepsin L light chain]
Length = 334
Score = 128 bits (322), Expect = 4e-30
Identities = 65/111 (58%), Positives = 78/111 (70%), Gaps = 5/111 (4%)
Frame = +3
Query: 3 GFQNINSCNEKDLAVAVATVGPISVAIDVGY-SFQQYKQGVYYEAKCDPTIQNHAVLVVG 179
GF +I EK L AVATVGPISVA+D + S Q Y G+YYE C +H VL+VG
Sbjct: 224 GFVDIPQ-QEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVG 282
Query: 180 YGVE----NGHKYWLVKNSWGPSWGMNGYIKMSKDRDNNCGIATTASFPIV 320
YG E N +KYWLVKNSWG WGM GYIK++KDRDN+CG+AT AS+P+V
Sbjct: 283 YGYEGTDSNKNKYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYPVV 333
>sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted protein) (MEP) (Cyclic
protein 2) (CP-2) [Contains: Cathepsin L heavy chain;
Cathepsin L light chain]
Length = 334
Score = 127 bits (320), Expect = 8e-30
Identities = 66/111 (59%), Positives = 78/111 (70%), Gaps = 5/111 (4%)
Frame = +3
Query: 3 GFQNINSCNEKDLAVAVATVGPISVAIDVGY-SFQQYKQGVYYEAKCDPTIQNHAVLVVG 179
GF +I EK L AVATVGPISVA+D + S Q Y G+YYE C +H VLVVG
Sbjct: 224 GFVDIPQ-QEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKDLDHGVLVVG 282
Query: 180 YGVE----NGHKYWLVKNSWGPSWGMNGYIKMSKDRDNNCGIATTASFPIV 320
YG E N KYWLVKNSWG WGM+GYIK++KDR+N+CG+AT AS+PIV
Sbjct: 283 YGYEGTDSNKDKYWLVKNSWGKEWGMDGYIKIAKDRNNHCGLATAASYPIV 333
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,058,960
Number of Sequences: 369166
Number of extensions: 934721
Number of successful extensions: 2710
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2433
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2512
length of database: 68,354,980
effective HSP length: 100
effective length of database: 49,881,480
effective search space used: 2144903640
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)