Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_006_H23
(724 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P28066|PSA5_HUMAN Proteasome subunit alpha type 5 (Prote... 317 3e-86
sp|P34064|PSA5_RAT Proteasome subunit alpha type 5 (Proteas... 312 5e-85
sp|Q95083|PSA5_DROME Proteasome subunit alpha type 5 293 3e-79
sp|Q9LSU1|PSA5_ORYSA Proteasome subunit alpha type 5 (20S p... 280 4e-75
sp|Q42134|PSA5B_ARATH Proteasome subunit alpha type 5-B (20... 278 8e-75
sp|Q9M4T8|PSA5_SOYBN Proteasome subunit alpha type 5 (20S p... 277 2e-74
sp|O81149|PSA5A_ARATH Proteasome subunit alpha type 5-A (20... 276 3e-74
sp|Q9UT97|PSA5_SCHPO Probable proteasome subunit alpha type 5 267 2e-71
sp|Q94561|PSA5_ENTHI Proteasome subunit alpha type 5 256 4e-68
sp|Q95008|PSA5_CAEEL Proteasome subunit alpha type 5 (Prote... 254 2e-67
>sp|P28066|PSA5_HUMAN Proteasome subunit alpha type 5 (Proteasome zeta chain) (Macropain
zeta chain) (Multicatalytic endopeptidase complex zeta
chain)
sp|Q9Z2U1|PSA5_MOUSE Proteasome subunit alpha type 5 (Proteasome zeta chain) (Macropain
zeta chain) (Multicatalytic endopeptidase complex zeta
chain)
Length = 241
Score = 317 bits (811), Expect = 3e-86
Identities = 152/235 (64%), Positives = 192/235 (81%)
Frame = +2
Query: 2 TNSEYDHGVNTFSPEGRLFQVEYAIEATKLGSTAIGIKTTHGVVLAVEKRITSPLLVPSS 181
T SEYD GVNTFSPEGRLFQVEYAIEA KLGSTAIGI+T+ GV LAVEKRITSPL+ PSS
Sbjct: 4 TRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSS 63
Query: 182 VEKIFKVDDYTAIAVSGLVADSRILVEKARVESTNHWFNHNERMAIESITKAVSKMALSF 361
+EKI ++D + A+SGL+AD++ L++KARVE+ NHWF +NE M +ES+T+AVS +AL F
Sbjct: 64 IEKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQF 123
Query: 362 ATNDSEPAAMSRPFGVALLFAGVDENGPQLLHMDPSGTYINYYAKAIGSGCEGAQQSLQE 541
D++P AMSRPFGVALLF GVDE GPQL HMDPSGT++ A+AIGS EGAQ SLQE
Sbjct: 124 GEEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQE 183
Query: 542 IYNKNMTIEEAAMEALSILKHVMEEKLDCTNIEMCSITEKDKYHLYTKEEVQKVI 706
+Y+K+MT++EA +L ILK VMEEKL+ TNIE+ ++ +H++TKEE+++VI
Sbjct: 184 VYHKSMTLKEAIKSSLIILKQVMEEKLNATNIELATVQPGQNFHMFTKEELEEVI 238
>sp|P34064|PSA5_RAT Proteasome subunit alpha type 5 (Proteasome zeta chain) (Macropain
zeta chain) (Multicatalytic endopeptidase complex zeta
chain)
Length = 241
Score = 312 bits (800), Expect = 5e-85
Identities = 150/235 (63%), Positives = 190/235 (80%)
Frame = +2
Query: 2 TNSEYDHGVNTFSPEGRLFQVEYAIEATKLGSTAIGIKTTHGVVLAVEKRITSPLLVPSS 181
T SEYD GVNTFSPEGRLFQVEYAIE KLGSTAIGI+T+ GV LAVEKRITSPL+ PSS
Sbjct: 4 TRSEYDRGVNTFSPEGRLFQVEYAIEGHKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSS 63
Query: 182 VEKIFKVDDYTAIAVSGLVADSRILVEKARVESTNHWFNHNERMAIESITKAVSKMALSF 361
+EKI ++D + A+SGL+AD++ L++KARVE+ NHWF +NE M +ES+T+AVS +AL F
Sbjct: 64 IEKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQF 123
Query: 362 ATNDSEPAAMSRPFGVALLFAGVDENGPQLLHMDPSGTYINYYAKAIGSGCEGAQQSLQE 541
D++P AMSRPFGVALLF GVDE GPQL HMDPSGT++ A+AIGS EGAQ SLQE
Sbjct: 124 GEEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQE 183
Query: 542 IYNKNMTIEEAAMEALSILKHVMEEKLDCTNIEMCSITEKDKYHLYTKEEVQKVI 706
+Y+K+ T++EA +L ILK VMEEKL+ TNIE+ ++ +H++TKEE+++VI
Sbjct: 184 VYHKSTTLKEAIKSSLIILKQVMEEKLNATNIELATVQPGQNFHMFTKEELEEVI 238
>sp|Q95083|PSA5_DROME Proteasome subunit alpha type 5
Length = 244
Score = 293 bits (750), Expect = 3e-79
Identities = 149/237 (62%), Positives = 194/237 (81%), Gaps = 2/237 (0%)
Frame = +2
Query: 2 TNSEYDHGVNTFSPEGRLFQVEYAIEATKLGSTAIGIKTTHGVVLAVEKRITSPLLVPSS 181
T SEYD GVNTFSPEGRLFQVEYAIEA KLGSTAIGI T GVVLAVEKRITSPL+VPS+
Sbjct: 4 TRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGICTPEGVVLAVEKRITSPLMVPST 63
Query: 182 VEKIFKVDDYTAIAVSGLVADSRILVEKARVESTNHWFNHNERMAIESITKAVSKMALSF 361
VEKI +VD + A SGL+AD+R L+E+ARVE NHWF +NERM+IES +AVS +A+ F
Sbjct: 64 VEKIVEVDKHIGCATSGLMADARTLIERARVECQNHWFVYNERMSIESCAQAVSTLAIQF 123
Query: 362 A-TNDSE-PAAMSRPFGVALLFAGVDENGPQLLHMDPSGTYINYYAKAIGSGCEGAQQSL 535
+ DS+ AAMSRPFGVA+LFAG++ PQL HMDPSGT++ + AKAIGSG EGAQQ+L
Sbjct: 124 GDSGDSDGAAAMSRPFGVAILFAGIEAGQPQLWHMDPSGTFVRHGAKAIGSGSEGAQQNL 183
Query: 536 QEIYNKNMTIEEAAMEALSILKHVMEEKLDCTNIEMCSITEKDKYHLYTKEEVQKVI 706
Q+++ ++T++EA +L+ LK VMEEKL+ TN+E+ ++T++ +++++TKEEV++ I
Sbjct: 184 QDLFRPDLTLDEAIDISLNTLKQVMEEKLNSTNVEVMTMTKEREFYMFTKEEVEQHI 240
>sp|Q9LSU1|PSA5_ORYSA Proteasome subunit alpha type 5 (20S proteasome alpha subunit E)
(20S proteasome subunit alpha-5)
Length = 237
Score = 280 bits (715), Expect = 4e-75
Identities = 147/235 (62%), Positives = 178/235 (75%)
Frame = +2
Query: 2 TNSEYDHGVNTFSPEGRLFQVEYAIEATKLGSTAIGIKTTHGVVLAVEKRITSPLLVPSS 181
T +EYD GVNTFSPEGRLFQVEYAIEA KLGSTAIG+KT GVVLAVEKR+TSPLL PSS
Sbjct: 4 TRTEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGLKTKDGVVLAVEKRVTSPLLEPSS 63
Query: 182 VEKIFKVDDYTAIAVSGLVADSRILVEKARVESTNHWFNHNERMAIESITKAVSKMALSF 361
VEKI ++D++ A+SGL+AD+R LVE ARVE+ NH F++ E M +ES T+A+ +AL F
Sbjct: 64 VEKIMEIDEHIGCAMSGLIADARTLVEHARVETQNHRFSYGEPMTVESTTQAICDLALRF 123
Query: 362 ATNDSEPAAMSRPFGVALLFAGVDENGPQLLHMDPSGTYINYYAKAIGSGCEGAQQSLQE 541
D E +MSRPFGV+LL AG DENGP L + DPSGT+ AKAIGSG EGA SLQE
Sbjct: 124 GEGDEE--SMSRPFGVSLLIAGHDENGPSLYYTDPSGTFWQCNAKAIGSGSEGADSSLQE 181
Query: 542 IYNKNMTIEEAAMEALSILKHVMEEKLDCTNIEMCSITEKDKYHLYTKEEVQKVI 706
YNK +T++EA ALSILK VMEEK+ N+++ ++ YHLYT EV+ VI
Sbjct: 182 QYNKELTLQEAETIALSILKQVMEEKVTPNNVDIAKVS--PNYHLYTPAEVEAVI 234
>sp|Q42134|PSA5B_ARATH Proteasome subunit alpha type 5-B (20S proteasome alpha subunit
E-2) (Proteasome component Z)
Length = 237
Score = 278 bits (712), Expect = 8e-75
Identities = 146/237 (61%), Positives = 180/237 (75%)
Frame = +2
Query: 2 TNSEYDHGVNTFSPEGRLFQVEYAIEATKLGSTAIGIKTTHGVVLAVEKRITSPLLVPSS 181
T +EYD GVNTFSPEGRLFQVEYAIEA KLGSTAIG+KT GVVLAVEKRITSPLL PSS
Sbjct: 4 TRTEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGVKTKEGVVLAVEKRITSPLLEPSS 63
Query: 182 VEKIFKVDDYTAIAVSGLVADSRILVEKARVESTNHWFNHNERMAIESITKAVSKMALSF 361
VEKI ++DD+ A+SGL+AD+R LVE ARVE+ NH F++ E M +ES T+A+ +AL F
Sbjct: 64 VEKIMEIDDHIGCAMSGLIADARTLVEHARVETQNHRFSYGEPMTVESTTQALCDLALRF 123
Query: 362 ATNDSEPAAMSRPFGVALLFAGVDENGPQLLHMDPSGTYINYYAKAIGSGCEGAQQSLQE 541
+ E +MSRPFGV+LL AG DENGP L + DPSGT+ AKAIGSG EGA SLQE
Sbjct: 124 GEGEEE--SMSRPFGVSLLIAGHDENGPSLYYTDPSGTFWQCNAKAIGSGSEGADSSLQE 181
Query: 542 IYNKNMTIEEAAMEALSILKHVMEEKLDCTNIEMCSITEKDKYHLYTKEEVQKVIDK 712
+NK++T++EA A+SILK VMEEK+ N+++ + YHLYT +EV+ VI +
Sbjct: 182 QFNKDITLQEAETIAVSILKQVMEEKVTPNNVDIAKVA--PAYHLYTPQEVEAVISR 236
>sp|Q9M4T8|PSA5_SOYBN Proteasome subunit alpha type 5 (20S proteasome alpha subunit E)
(20S proteasome subunit alpha-5)
Length = 237
Score = 277 bits (709), Expect = 2e-74
Identities = 146/237 (61%), Positives = 178/237 (75%)
Frame = +2
Query: 2 TNSEYDHGVNTFSPEGRLFQVEYAIEATKLGSTAIGIKTTHGVVLAVEKRITSPLLVPSS 181
T +EYD GVNTFSPEGRLFQVEYAIEA KLGSTAIG+KT GVVLAVEKRITSPLL PSS
Sbjct: 4 TRTEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGLKTKEGVVLAVEKRITSPLLEPSS 63
Query: 182 VEKIFKVDDYTAIAVSGLVADSRILVEKARVESTNHWFNHNERMAIESITKAVSKMALSF 361
VEKI ++D++ A+SGL+AD+R LVE ARVE+ NH F++ E M +ES T+A+ +AL F
Sbjct: 64 VEKIMEIDEHIGCAMSGLIADARTLVEHARVETQNHRFSYGEPMTVESTTQALCDLALRF 123
Query: 362 ATNDSEPAAMSRPFGVALLFAGVDENGPQLLHMDPSGTYINYYAKAIGSGCEGAQQSLQE 541
D E +MSRPFGV+LL AG DENGP L + DPSGT+ KAIGSG EGA SLQE
Sbjct: 124 GEGDEE--SMSRPFGVSLLIAGHDENGPSLYYTDPSGTFWQCNGKAIGSGSEGADSSLQE 181
Query: 542 IYNKNMTIEEAAMEALSILKHVMEEKLDCTNIEMCSITEKDKYHLYTKEEVQKVIDK 712
+NK++T++EA ALSILK VMEEK+ N+++ + YHLYT EV+ VI +
Sbjct: 182 QFNKDLTLQEAETIALSILKQVMEEKVTPNNVDIAKVA--PTYHLYTPSEVEAVISR 236
>sp|O81149|PSA5A_ARATH Proteasome subunit alpha type 5-A (20S proteasome alpha subunit
E-1)
Length = 237
Score = 276 bits (707), Expect = 3e-74
Identities = 145/235 (61%), Positives = 179/235 (76%)
Frame = +2
Query: 2 TNSEYDHGVNTFSPEGRLFQVEYAIEATKLGSTAIGIKTTHGVVLAVEKRITSPLLVPSS 181
T +EYD GVNTFSPEGRLFQVEYAIEA KLGSTAIG+KT GVVLAVEKRITSPLL PSS
Sbjct: 4 TRTEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGVKTKEGVVLAVEKRITSPLLEPSS 63
Query: 182 VEKIFKVDDYTAIAVSGLVADSRILVEKARVESTNHWFNHNERMAIESITKAVSKMALSF 361
VEKI ++DD+ A+SGL+AD+R LVE ARVE+ NH F++ E M +ES T+A+ +AL F
Sbjct: 64 VEKIMEIDDHIGCAMSGLIADARTLVEHARVETQNHRFSYGEPMTVESTTQALCDLALRF 123
Query: 362 ATNDSEPAAMSRPFGVALLFAGVDENGPQLLHMDPSGTYINYYAKAIGSGCEGAQQSLQE 541
+ E +MSRPFGV+LL AG DENGP L + DPSGT+ AKAIGSG EGA SLQE
Sbjct: 124 GEGEEE--SMSRPFGVSLLIAGHDENGPSLYYTDPSGTFWQCNAKAIGSGSEGADSSLQE 181
Query: 542 IYNKNMTIEEAAMEALSILKHVMEEKLDCTNIEMCSITEKDKYHLYTKEEVQKVI 706
+NK+++++EA A+SILK VMEEK+ N+++ + YHLYT +EV+ VI
Sbjct: 182 QFNKDLSLQEAETIAVSILKQVMEEKVTPNNVDIAKVA--PAYHLYTPQEVEAVI 234
>sp|Q9UT97|PSA5_SCHPO Probable proteasome subunit alpha type 5
Length = 247
Score = 267 bits (682), Expect = 2e-71
Identities = 132/239 (55%), Positives = 174/239 (72%), Gaps = 1/239 (0%)
Frame = +2
Query: 2 TNSEYDHGVNTFSPEGRLFQVEYAIEATKLGSTAIGIKTTHGVVLAVEKRITSPLLVPSS 181
T SEYD GVNTFSPEGRLFQVEYAIEA KLGSTAIG+KT VVL VEKR+TSPL+ S
Sbjct: 4 TRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGVKTKDAVVLGVEKRLTSPLMESHS 63
Query: 182 VEKIFKVDDYTAIAVSGLVADSRILVEKARVESTNHWFNHNERMAIESITKAVSKMALSF 361
VEK+F++D + A+SGL AD+R ++E ARV++ NH F ++E IES T+++ +AL F
Sbjct: 64 VEKLFEIDSHIGCAISGLTADARTIIEHARVQTQNHRFTYDEPQGIESTTQSICDLALRF 123
Query: 362 AT-NDSEPAAMSRPFGVALLFAGVDENGPQLLHMDPSGTYINYYAKAIGSGCEGAQQSLQ 538
D E MSRPFGVALL AG+DE+GPQL H +PSGTY Y AKAIGSG E A+ L
Sbjct: 124 GEGEDGEERIMSRPFGVALLIAGIDEHGPQLYHSEPSGTYFRYEAKAIGSGSEPAKSELV 183
Query: 539 EIYNKNMTIEEAAMEALSILKHVMEEKLDCTNIEMCSITEKDKYHLYTKEEVQKVIDKK 715
+ ++K+MT+EEA + L +L+ VMEEKLD N+++ +T + +H+Y EE+ + ++
Sbjct: 184 KEFHKDMTLEEAEVLILKVLRQVMEEKLDSKNVQLAKVTAEGGFHIYNDEEMADAVARE 242
>sp|Q94561|PSA5_ENTHI Proteasome subunit alpha type 5
Length = 247
Score = 256 bits (654), Expect = 4e-68
Identities = 131/236 (55%), Positives = 171/236 (72%), Gaps = 1/236 (0%)
Frame = +2
Query: 2 TNSEYDHGVNTFSPEGRLFQVEYAIEATKLGSTAIGIKTTHGVVLAVEKRITSPLLVPSS 181
T +E DHGVNTFS EGRLFQVEYA EA KLGST IGI+T GVVLAVEKRI+SPL++ SS
Sbjct: 4 TKNENDHGVNTFSSEGRLFQVEYATEAMKLGSTVIGIQTKEGVVLAVEKRISSPLMLGSS 63
Query: 182 VEKIFKVDDYTAIAVSGLVADSRILVEKARVESTNHWFNHNERMAIESITKAVSKMALSF 361
+EKI ++DD+ AVSGL AD+R L++ AR+E+ NH F ++E + +E + +A+S ++L F
Sbjct: 64 IEKIIEIDDHIGAAVSGLTADARTLIDNARLEAQNHRFMYDEPINVEVVAQAISDLSLRF 123
Query: 362 ATNDSEPAAMSRPFGVALLFAGVDENGPQLLHMDPSGTYINYYAKAIGSGCEGAQQSLQE 541
+ MSRPFGVALL AGVDE GP+L DPSG +I +YAKA G+G E AQ L E
Sbjct: 124 GEGSRKKKVMSRPFGVALLIAGVDETGPRLFQTDPSGMFIEFYAKATGAGTEAAQSILHE 183
Query: 542 IYNKNMTIEEAAMEALSILKHVMEEKLDCTNIEMCSIT-EKDKYHLYTKEEVQKVI 706
YNK+MT+ EA + ALS LK VMEEKL+ N+E+ +T EK K+ + ++ +I
Sbjct: 184 KYNKSMTLREAEILALSTLKQVMEEKLNSKNVEVALVTVEKKKFEIMDTAFIENLI 239
>sp|Q95008|PSA5_CAEEL Proteasome subunit alpha type 5 (Proteasome subunit alpha 5)
Length = 248
Score = 254 bits (648), Expect = 2e-67
Identities = 125/217 (57%), Positives = 170/217 (78%)
Frame = +2
Query: 2 TNSEYDHGVNTFSPEGRLFQVEYAIEATKLGSTAIGIKTTHGVVLAVEKRITSPLLVPSS 181
T SEYD GVNTFSPEGRLFQVEYAIEA KLGST+IGIKT+ GV+LA EKR TS L+V +
Sbjct: 4 TRSEYDRGVNTFSPEGRLFQVEYAIEAVKLGSTSIGIKTSEGVLLAAEKRSTSKLMVNDA 63
Query: 182 VEKIFKVDDYTAIAVSGLVADSRILVEKARVESTNHWFNHNERMAIESITKAVSKMALSF 361
+EKI KVD + + +GL+ADSR LVE+A++E+ N WF +N ++ +E +T++V+ +AL F
Sbjct: 64 IEKISKVDQHIGVTFAGLIADSRTLVERAQIEAQNFWFTYNRKIRVEDVTQSVANLALQF 123
Query: 362 ATNDSEPAAMSRPFGVALLFAGVDENGPQLLHMDPSGTYINYYAKAIGSGCEGAQQSLQE 541
+D + A+MSRPFGVA+LFAGVD+ G +L H+DPSGT+I+ AK+IG+ +GA+Q+L+E
Sbjct: 124 GDDDVK-ASMSRPFGVAMLFAGVDQEGAKLFHLDPSGTFIDCKAKSIGAASDGAEQNLKE 182
Query: 542 IYNKNMTIEEAAMEALSILKHVMEEKLDCTNIEMCSI 652
Y+ +TI+E AL+ILK VMEEKL+ N+E+ I
Sbjct: 183 QYHDALTIKEGLKMALAILKQVMEEKLNSANVEVVVI 219
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,073,700
Number of Sequences: 369166
Number of extensions: 1496113
Number of successful extensions: 4676
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4309
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4446
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6462248555
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)