Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_006_E03
(460 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P41570|6PGD_CERCA 6-phosphogluconate dehydrogenase, deca... 176 2e-44
sp|O60037|6PGD_CUNEL 6-phosphogluconate dehydrogenase, deca... 172 2e-43
sp|P41572|6PGD_DROME 6-phosphogluconate dehydrogenase, deca... 172 3e-43
sp|P41573|6PGD_DROSI 6-phosphogluconate dehydrogenase, deca... 172 3e-43
sp|Q9DCD0|6PGD_MOUSE 6-phosphogluconate dehydrogenase, deca... 168 5e-42
sp|P52209|6PGD_HUMAN 6-phosphogluconate dehydrogenase, deca... 164 1e-40
sp|P00349|6PGD_SHEEP 6-phosphogluconate dehydrogenase, deca... 163 1e-40
sp|Q17761|6PGD_CAEEL 6-phosphogluconate dehydrogenase, deca... 163 1e-40
sp|P14332|6PGD_PIG 6-phosphogluconate dehydrogenase, decarb... 162 3e-40
sp|P53319|6PGD2_YEAST 6-phosphogluconate dehydrogenase, dec... 157 1e-38
>sp|P41570|6PGD_CERCA 6-phosphogluconate dehydrogenase, decarboxylating
Length = 481
Score = 176 bits (446), Expect = 2e-44
Identities = 88/126 (69%), Positives = 96/126 (76%)
Frame = +3
Query: 36 IALMWRGGCIIRSRFLQNIKDAYEKNKNLSILLFDKFFQSEILKCQESWRHVVANAALHG 215
IALMWRGGCIIRS FL NIKDAY +N LS LL D FF+ I Q SWR VVANA L G
Sbjct: 356 IALMWRGGCIIRSVFLGNIKDAYTRNPQLSNLLLDDFFKKAIEVGQNSWRQVVANAFLWG 415
Query: 216 IPTPAFSCALAFYDGLRTEKLPANLIQAQRDLFGAHQYQLLDHPGTYEHTDWTGHGGNAA 395
IP PA S AL+FYDG RTEKLPANL+QAQRD FGAH Y+LL G + HT+WTG GGN +
Sbjct: 416 IPVPALSTALSFYDGYRTEKLPANLLQAQRDYFGAHTYELLGAEGKFVHTNWTGTGGNVS 475
Query: 396 ASTYQA 413
ASTYQA
Sbjct: 476 ASTYQA 481
>sp|O60037|6PGD_CUNEL 6-phosphogluconate dehydrogenase, decarboxylating
Length = 485
Score = 172 bits (437), Expect = 2e-43
Identities = 84/126 (66%), Positives = 94/126 (74%)
Frame = +3
Query: 36 IALMWRGGCIIRSRFLQNIKDAYEKNKNLSILLFDKFFQSEILKCQESWRHVVANAALHG 215
IALMWRGGCIIRS FL I+DAY KN L LLFD FF+ K Q++WR+V A A L G
Sbjct: 360 IALMWRGGCIIRSVFLGKIRDAYTKNPELENLLFDDFFKDATAKAQDAWRNVTAQAVLMG 419
Query: 216 IPTPAFSCALAFYDGLRTEKLPANLIQAQRDLFGAHQYQLLDHPGTYEHTDWTGHGGNAA 395
IPTPA S AL FYDGLR E LPANL+QAQRD FGAH Y+LL PG + HT+WTG GGN +
Sbjct: 420 IPTPALSTALNFYDGLRHEILPANLLQAQRDYFGAHTYELLHTPGKWVHTNWTGRGGNVS 479
Query: 396 ASTYQA 413
ASTY A
Sbjct: 480 ASTYDA 485
>sp|P41572|6PGD_DROME 6-phosphogluconate dehydrogenase, decarboxylating
Length = 481
Score = 172 bits (436), Expect = 3e-43
Identities = 85/126 (67%), Positives = 94/126 (74%)
Frame = +3
Query: 36 IALMWRGGCIIRSRFLQNIKDAYEKNKNLSILLFDKFFQSEILKCQESWRHVVANAALHG 215
IALMWRGGCIIRS FL NIKDAY LS LL D FF+ I + Q+SWR VVANA G
Sbjct: 356 IALMWRGGCIIRSVFLGNIKDAYTSQPELSNLLLDDFFKKAIERGQDSWREVVANAFRWG 415
Query: 216 IPTPAFSCALAFYDGLRTEKLPANLIQAQRDLFGAHQYQLLDHPGTYEHTDWTGHGGNAA 395
IP PA S AL+FYDG RT KLPANL+QAQRD FGAH Y+LL G + HT+WTG GGN +
Sbjct: 416 IPVPALSTALSFYDGYRTAKLPANLLQAQRDYFGAHTYELLGQEGQFHHTNWTGTGGNVS 475
Query: 396 ASTYQA 413
ASTYQA
Sbjct: 476 ASTYQA 481
>sp|P41573|6PGD_DROSI 6-phosphogluconate dehydrogenase, decarboxylating
Length = 481
Score = 172 bits (436), Expect = 3e-43
Identities = 85/126 (67%), Positives = 94/126 (74%)
Frame = +3
Query: 36 IALMWRGGCIIRSRFLQNIKDAYEKNKNLSILLFDKFFQSEILKCQESWRHVVANAALHG 215
IALMWRGGCIIRS FL NIKDAY LS LL D FF+ I + Q+SWR VVANA G
Sbjct: 356 IALMWRGGCIIRSVFLGNIKDAYTSQPQLSNLLLDDFFKKAIERGQDSWREVVANAFRWG 415
Query: 216 IPTPAFSCALAFYDGLRTEKLPANLIQAQRDLFGAHQYQLLDHPGTYEHTDWTGHGGNAA 395
IP PA S AL+FYDG RT KLPANL+QAQRD FGAH Y+LL G + HT+WTG GGN +
Sbjct: 416 IPVPALSTALSFYDGYRTAKLPANLLQAQRDYFGAHTYELLGQEGQFHHTNWTGTGGNVS 475
Query: 396 ASTYQA 413
ASTYQA
Sbjct: 476 ASTYQA 481
>sp|Q9DCD0|6PGD_MOUSE 6-phosphogluconate dehydrogenase, decarboxylating
Length = 483
Score = 168 bits (426), Expect = 5e-42
Identities = 78/126 (61%), Positives = 94/126 (74%)
Frame = +3
Query: 36 IALMWRGGCIIRSRFLQNIKDAYEKNKNLSILLFDKFFQSEILKCQESWRHVVANAALHG 215
IALMWRGGCIIRS FL IKDA+E+N L LL D FF+S + CQ+SWR V++ G
Sbjct: 358 IALMWRGGCIIRSVFLGKIKDAFERNPELQNLLLDDFFKSAVDNCQDSWRRVISTGVQAG 417
Query: 216 IPTPAFSCALAFYDGLRTEKLPANLIQAQRDLFGAHQYQLLDHPGTYEHTDWTGHGGNAA 395
IP P F+ AL+FYDG R E LPANLIQAQRD FGAH Y+LL PG + HT+WTGHGG+ +
Sbjct: 418 IPMPCFTTALSFYDGYRHEMLPANLIQAQRDYFGAHTYELLTKPGEFIHTNWTGHGGSVS 477
Query: 396 ASTYQA 413
+S+Y A
Sbjct: 478 SSSYNA 483
>sp|P52209|6PGD_HUMAN 6-phosphogluconate dehydrogenase, decarboxylating
Length = 483
Score = 164 bits (414), Expect = 1e-40
Identities = 76/126 (60%), Positives = 92/126 (73%)
Frame = +3
Query: 36 IALMWRGGCIIRSRFLQNIKDAYEKNKNLSILLFDKFFQSEILKCQESWRHVVANAALHG 215
IALMWRGGCIIRS FL IKDA+++N L LL D FF+S + CQ+SWR V+ G
Sbjct: 358 IALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAG 417
Query: 216 IPTPAFSCALAFYDGLRTEKLPANLIQAQRDLFGAHQYQLLDHPGTYEHTDWTGHGGNAA 395
IP P F+ AL+FYDG R E LPA+LIQAQRD FGAH Y+LL PG + HT+WTGHGG +
Sbjct: 418 IPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVS 477
Query: 396 ASTYQA 413
+S+Y A
Sbjct: 478 SSSYNA 483
>sp|P00349|6PGD_SHEEP 6-phosphogluconate dehydrogenase, decarboxylating
Length = 483
Score = 163 bits (413), Expect = 1e-40
Identities = 75/126 (59%), Positives = 92/126 (73%)
Frame = +3
Query: 36 IALMWRGGCIIRSRFLQNIKDAYEKNKNLSILLFDKFFQSEILKCQESWRHVVANAALHG 215
IALMWRGGCIIRS FL IKDA+++N L LL D FF+S + CQ+SWR ++ G
Sbjct: 358 IALMWRGGCIIRSVFLGKIKDAFDRNPGLQNLLLDDFFKSAVENCQDSWRRAISTGVQAG 417
Query: 216 IPTPAFSCALAFYDGLRTEKLPANLIQAQRDLFGAHQYQLLDHPGTYEHTDWTGHGGNAA 395
IP P F+ AL+FYDG R LPANLIQAQRD FGAH Y+LL PG + HT+WTGHGG+ +
Sbjct: 418 IPMPCFTTALSFYDGYRHAMLPANLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGSVS 477
Query: 396 ASTYQA 413
+S+Y A
Sbjct: 478 SSSYNA 483
>sp|Q17761|6PGD_CAEEL 6-phosphogluconate dehydrogenase, decarboxylating
Length = 484
Score = 163 bits (413), Expect = 1e-40
Identities = 79/126 (62%), Positives = 93/126 (73%)
Frame = +3
Query: 36 IALMWRGGCIIRSRFLQNIKDAYEKNKNLSILLFDKFFQSEILKCQESWRHVVANAALHG 215
IALMWRGGCIIRSRFL +I+ A++KNK LS LL D FF I + Q+SWR VV A G
Sbjct: 359 IALMWRGGCIIRSRFLGDIEHAFQKNKQLSNLLLDDFFTKAITEAQDSWRVVVCAAVRLG 418
Query: 216 IPTPAFSCALAFYDGLRTEKLPANLIQAQRDLFGAHQYQLLDHPGTYEHTDWTGHGGNAA 395
IP PAFS ALAFYDG +E +PANL+QAQRD FGAH Y+LL PGT+ HT+WTG GG
Sbjct: 419 IPVPAFSSALAFYDGYTSEVVPANLLQAQRDYFGAHTYELLAKPGTWVHTNWTGTGGRVT 478
Query: 396 ASTYQA 413
++ Y A
Sbjct: 479 SNAYNA 484
>sp|P14332|6PGD_PIG 6-phosphogluconate dehydrogenase, decarboxylating
Length = 250
Score = 162 bits (411), Expect = 3e-40
Identities = 75/124 (60%), Positives = 91/124 (73%)
Frame = +3
Query: 42 LMWRGGCIIRSRFLQNIKDAYEKNKNLSILLFDKFFQSEILKCQESWRHVVANAALHGIP 221
LMWRGGCIIRS FL IKDA+++N L LL D FF+S + CQ+SWR V+ GIP
Sbjct: 127 LMWRGGCIIRSVFLGKIKDAFDRNPGLQNLLLDDFFKSAVEDCQDSWRRAVSTGVQTGIP 186
Query: 222 TPAFSCALAFYDGLRTEKLPANLIQAQRDLFGAHQYQLLDHPGTYEHTDWTGHGGNAAAS 401
P F+ AL+FYDG R E LPANLIQAQRD FGAH Y+LL PG + HT+WTGHGG+ ++S
Sbjct: 187 MPCFTTALSFYDGYRHEMLPANLIQAQRDYFGAHTYELLAKPGHFVHTNWTGHGGSVSSS 246
Query: 402 TYQA 413
+Y A
Sbjct: 247 SYNA 250
>sp|P53319|6PGD2_YEAST 6-phosphogluconate dehydrogenase, decarboxylating 2
Length = 492
Score = 157 bits (396), Expect = 1e-38
Identities = 77/133 (57%), Positives = 94/133 (70%), Gaps = 7/133 (5%)
Frame = +3
Query: 36 IALMWRGGCIIRSRFLQNIKDAYEKNKNLSILLFDKFFQSEILKCQESWRHVVANAALHG 215
IALMWRGGCIIRS FL I AY + +L LLF++FF S + K Q WR +A AA +G
Sbjct: 360 IALMWRGGCIIRSVFLAEITKAYRDDPDLENLLFNEFFASAVTKAQSGWRRTIALAATYG 419
Query: 216 IPTPAFSCALAFYDGLRTEKLPANLIQAQRDLFGAHQYQLLDHPGTYE-------HTDWT 374
IPTPAFS ALAFYDG R+E+LPANL+QAQRD FGAH +++L + H +WT
Sbjct: 420 IPTPAFSTALAFYDGYRSERLPANLLQAQRDYFGAHTFRILPECASAHLPVDKDIHINWT 479
Query: 375 GHGGNAAASTYQA 413
GHGGN ++STYQA
Sbjct: 480 GHGGNISSSTYQA 492
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,045,500
Number of Sequences: 369166
Number of extensions: 1157319
Number of successful extensions: 2961
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2870
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2941
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2534533995
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)