Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_006_C20 (415 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P51637|CAV3_MOUSE Caveolin-3 (M-caveolin) 70 2e-12 sp|Q6RVA9|CAV1_PIG Caveolin-1 68 6e-12 sp|Q9YGM8|CAV1_FUGRU Caveolin-1 68 6e-12 sp|P51638|CAV3_RAT Caveolin-3 68 8e-12 sp|P33724|CAV1_CANFA Caveolin-1 (Vesicular integral-membran... 68 8e-12 sp|Q03135|CAV1_HUMAN Caveolin-1 67 1e-11 sp|P56539|CAV3_HUMAN Caveolin-3 (M-caveolin) 66 2e-11 sp|P49817|CAV1_MOUSE Caveolin-1 66 2e-11 sp|P79132|CAV1_BOVIN Caveolin-1 66 3e-11 sp|P41350|CAV1_RAT Caveolin-1 65 7e-11
>sp|P51637|CAV3_MOUSE Caveolin-3 (M-caveolin) Length = 151 Score = 70.1 bits (170), Expect = 2e-12 Identities = 30/72 (41%), Positives = 39/72 (54%) Frame = +3 Query: 9 WEDNFAEPEGVKSCDCLWKASFKCFNGGRDCCYRXXXXXXXXXXXXYWGCFYACLACCHI 188 +ED AEPEG S D +WK SF F + CYR WG +AC++ CHI Sbjct: 41 FEDVIAEPEGTYSFDGVWKVSFTTFTVSKYWCYRLLSTLLGVPLALLWGFLFACISFCHI 100 Query: 189 WCLTPCIKIYVL 224 W + PCIK Y++ Sbjct: 101 WAVVPCIKSYLI 112
>sp|Q6RVA9|CAV1_PIG Caveolin-1 Length = 178 Score = 68.2 bits (165), Expect = 6e-12 Identities = 36/109 (33%), Positives = 50/109 (45%) Frame = +3 Query: 9 WEDNFAEPEGVKSCDCLWKASFKCFNGGRDCCYRXXXXXXXXXXXXYWGCFYACLACCHI 188 +ED AEPEG S D +WKASF F + YR WG ++A L+ HI Sbjct: 68 FEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHI 127 Query: 189 WCLTPCIKIYVLHCALCKKLNKAFVDCCYGPCAEVWGLWGGHFRITMDK 335 W + PCIK +++ ++ +V P E G + RI M K Sbjct: 128 WAVVPCIKSFLIEIQCISRVYSIYVHTFCDPLFEAIGKIFSNIRINMQK 176
>sp|Q9YGM8|CAV1_FUGRU Caveolin-1 Length = 181 Score = 68.2 bits (165), Expect = 6e-12 Identities = 37/109 (33%), Positives = 48/109 (44%) Frame = +3 Query: 9 WEDNFAEPEGVKSCDCLWKASFKCFNGGRDCCYRXXXXXXXXXXXXYWGCFYACLACCHI 188 +ED AEP G S D +WKASF F + CYR WG F+A L+ HI Sbjct: 71 FEDVIAEPAGTYSFDGVWKASFTTFTVTKYWCYRLLTALVGIPLALIWGIFFAILSFIHI 130 Query: 189 WCLTPCIKIYVLHCALCKKLNKAFVDCCYGPCAEVWGLWGGHFRITMDK 335 W + PC+K Y++ ++ V P E G G RI K Sbjct: 131 WAVVPCVKSYLIEIHCISRVYSICVHTFCDPLFEAMGKCLGGVRIRTSK 179
>sp|P51638|CAV3_RAT Caveolin-3 Length = 151 Score = 67.8 bits (164), Expect = 8e-12 Identities = 28/72 (38%), Positives = 39/72 (54%) Frame = +3 Query: 9 WEDNFAEPEGVKSCDCLWKASFKCFNGGRDCCYRXXXXXXXXXXXXYWGCFYACLACCHI 188 +ED AEPEG S D +W+ S+ F + CYR WG +AC++ CHI Sbjct: 41 FEDVIAEPEGTYSFDGVWRVSYTTFTVSKYWCYRLLSTLLGVPLALLWGFLFACISFCHI 100 Query: 189 WCLTPCIKIYVL 224 W + PCIK Y++ Sbjct: 101 WAVVPCIKSYLI 112
>sp|P33724|CAV1_CANFA Caveolin-1 (Vesicular integral-membrane protein VIP21) Length = 178 Score = 67.8 bits (164), Expect = 8e-12 Identities = 36/109 (33%), Positives = 50/109 (45%) Frame = +3 Query: 9 WEDNFAEPEGVKSCDCLWKASFKCFNGGRDCCYRXXXXXXXXXXXXYWGCFYACLACCHI 188 +ED AEPEG S D +WKASF F + YR WG ++A L+ HI Sbjct: 68 FEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHI 127 Query: 189 WCLTPCIKIYVLHCALCKKLNKAFVDCCYGPCAEVWGLWGGHFRITMDK 335 W + PCIK +++ ++ +V P E G + RI M K Sbjct: 128 WAVVPCIKSFLIEIQCISRVYSIYVHTFCDPFFEAVGKIFSNIRINMQK 176
>sp|Q03135|CAV1_HUMAN Caveolin-1 Length = 178 Score = 67.0 bits (162), Expect = 1e-11 Identities = 35/109 (32%), Positives = 50/109 (45%) Frame = +3 Query: 9 WEDNFAEPEGVKSCDCLWKASFKCFNGGRDCCYRXXXXXXXXXXXXYWGCFYACLACCHI 188 +ED AEPEG S D +WKASF F + YR WG ++A L+ HI Sbjct: 68 FEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHI 127 Query: 189 WCLTPCIKIYVLHCALCKKLNKAFVDCCYGPCAEVWGLWGGHFRITMDK 335 W + PCIK +++ ++ +V P E G + RI + K Sbjct: 128 WAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQK 176
>sp|P56539|CAV3_HUMAN Caveolin-3 (M-caveolin) Length = 151 Score = 66.2 bits (160), Expect = 2e-11 Identities = 28/72 (38%), Positives = 38/72 (52%) Frame = +3 Query: 9 WEDNFAEPEGVKSCDCLWKASFKCFNGGRDCCYRXXXXXXXXXXXXYWGCFYACLACCHI 188 +ED AEP G S D +WK S+ F + CYR WG +AC++ CHI Sbjct: 41 FEDVIAEPVGTYSFDGVWKVSYTTFTVSKYWCYRLLSTLLGVPLALLWGFLFACISFCHI 100 Query: 189 WCLTPCIKIYVL 224 W + PCIK Y++ Sbjct: 101 WAVVPCIKSYLI 112
>sp|P49817|CAV1_MOUSE Caveolin-1 Length = 178 Score = 66.2 bits (160), Expect = 2e-11 Identities = 35/109 (32%), Positives = 50/109 (45%) Frame = +3 Query: 9 WEDNFAEPEGVKSCDCLWKASFKCFNGGRDCCYRXXXXXXXXXXXXYWGCFYACLACCHI 188 +ED AEPEG S D +WKASF F + YR WG ++A L+ HI Sbjct: 68 FEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSTIFGIPMALIWGIYFAILSFLHI 127 Query: 189 WCLTPCIKIYVLHCALCKKLNKAFVDCCYGPCAEVWGLWGGHFRITMDK 335 W + PCIK +++ ++ +V P E G + RI+ K Sbjct: 128 WAVVPCIKSFLIEIQCISRVYSIYVHTFCDPLFEAIGKIFSNIRISTQK 176
>sp|P79132|CAV1_BOVIN Caveolin-1 Length = 178 Score = 65.9 bits (159), Expect = 3e-11 Identities = 35/109 (32%), Positives = 49/109 (44%) Frame = +3 Query: 9 WEDNFAEPEGVKSCDCLWKASFKCFNGGRDCCYRXXXXXXXXXXXXYWGCFYACLACCHI 188 +ED AEPEG S D +WKASF F + YR WG ++A L+ HI Sbjct: 68 FEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHI 127 Query: 189 WCLTPCIKIYVLHCALCKKLNKAFVDCCYGPCAEVWGLWGGHFRITMDK 335 W + PCIK +++ ++ +V P E G + RI K Sbjct: 128 WAVVPCIKSFLIEIQCISRVYSIYVHTFCDPLFEAIGKIFSNIRINTQK 176
>sp|P41350|CAV1_RAT Caveolin-1 Length = 178 Score = 64.7 bits (156), Expect = 7e-11 Identities = 34/106 (32%), Positives = 49/106 (46%) Frame = +3 Query: 9 WEDNFAEPEGVKSCDCLWKASFKCFNGGRDCCYRXXXXXXXXXXXXYWGCFYACLACCHI 188 +ED AEPEG S D +WKASF F + YR WG ++A L+ HI Sbjct: 68 FEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSTIFGIPMALIWGIYFAILSFLHI 127 Query: 189 WCLTPCIKIYVLHCALCKKLNKAFVDCCYGPCAEVWGLWGGHFRIT 326 W + PCIK +++ ++ +V P E G + RI+ Sbjct: 128 WAVVPCIKSFLIEIQCISRVYSIYVHTFCDPLFEAIGKIFSNIRIS 173
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 47,357,154 Number of Sequences: 369166 Number of extensions: 851623 Number of successful extensions: 1830 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1791 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1825 length of database: 68,354,980 effective HSP length: 99 effective length of database: 50,066,215 effective search space used: 1902516170 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)