Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_006_C06
(798 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5ZLW3|DYM_CHICK Dymeclin 176 7e-44
sp|Q5RAW5|DYM_PONPY Dymeclin 174 3e-43
sp|Q8CHY3|DYM_MOUSE Dymeclin 172 7e-43
sp|Q7RTS9|DYM_HUMAN Dymeclin (Dyggve-Melchior-Clausen syndr... 172 7e-43
sp|Q8M355|RMAR_SACCA Mitochondrial ribosomal protein VAR1 36 0.14
sp|P57091|C18BA_PAEPP Parasporal crystal protein cry18Ba (P... 35 0.31
sp||Q9NZ56_2 [Segment 2 of 2] Formin-2 34 0.40
sp|O35161|CELR1_MOUSE Cadherin EGF LAG seven-pass G-type re... 34 0.53
sp|P20103|NISB_LACLA Nisin biosynthesis protein nisB 33 0.90
sp|P36626|REC8_SCHPO Meiotic recombination protein rec8 (Co... 33 0.90
>sp|Q5ZLW3|DYM_CHICK Dymeclin
Length = 669
Score = 176 bits (446), Expect = 7e-44
Identities = 88/233 (37%), Positives = 162/233 (69%), Gaps = 4/233 (1%)
Frame = +2
Query: 38 EKTITNISIGSLIVWILCRTIQFNFGHVGDRYIHINCLAALANMSSKFINLHPLASEQIM 217
E+ +T IS+GSL++ ++ RTIQ+N D+Y+H NCLAALANMS++F +LH A+++I+
Sbjct: 427 ERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRII 486
Query: 218 ILLNILLKR--KV--YLSNNLKNITENQDSEKFSNLSNNLSVIEEIIQMLVEIVNTALIF 385
L ++L K+ KV + +L+ ++ DS + + +L+VIEE+I+M++EI+N+ L
Sbjct: 487 SLFSLLSKKHNKVLEQATQSLRGSLDSNDS-PLPDYAQDLNVIEEVIRMMLEIINSCLTN 545
Query: 386 SLNNNPHMIHTFLYHKKLFSQMKINSHTETHLCNIDAILTYFSSKIEKELGKSVSSQNEV 565
SL++NP++++ LY + LF Q + + + + NID ++++FSS++E G +S + V
Sbjct: 546 SLHHNPNLVYALLYKRDLFEQFRTHPSFQDIMQNIDLVISFFSSRLE-HAGAELSVE-RV 603
Query: 566 LKVIKKFSPSINKLNNFKRFPELKFKYIEQESSDDFFVPYIWRLICKSSLIFF 724
L++IK+ + ++ K + ++FPELKFKY+E+E ++FF+PY+W L+ +++ +
Sbjct: 604 LEIIKQGAVALPK-DRLRKFPELKFKYVEEEQPEEFFIPYVWSLVYNAAVALY 655
>sp|Q5RAW5|DYM_PONPY Dymeclin
Length = 669
Score = 174 bits (441), Expect = 3e-43
Identities = 89/233 (38%), Positives = 158/233 (67%), Gaps = 6/233 (2%)
Frame = +2
Query: 35 NEKTITNISIGSLIVWILCRTIQFNFGHVGDRYIHINCLAALANMSSKFINLHPLASEQI 214
+E+ +T IS+GSL++ ++ RTIQ+N D+Y+H NCLAALANMS++F +LH A+++I
Sbjct: 426 SERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRI 485
Query: 215 MILLNILLKRKVYLSNNLKNITENQDSEKFSN------LSNNLSVIEEIIQMLVEIVNTA 376
+ L ++L K+ + L+ T++ SN + +L+VIEE+I+M++EI+N+
Sbjct: 486 ISLFSLLSKKH---NKVLEQATQSLRGSLSSNDVPLPDYAQDLNVIEEVIRMMLEIINSC 542
Query: 377 LIFSLNNNPHMIHTFLYHKKLFSQMKINSHTETHLCNIDAILTYFSSKIEKELGKSVSSQ 556
L SL++NP++++ LY + LF Q + + + + NID ++T+FSS++ + G +S +
Sbjct: 543 LTNSLHHNPNLVYALLYKRDLFEQFRTHPSFQDIMQNIDLVITFFSSRL-LQAGAELSVE 601
Query: 557 NEVLKVIKKFSPSINKLNNFKRFPELKFKYIEQESSDDFFVPYIWRLICKSSL 715
VL++IK+ ++ K + K+FPELKFKY+E+E ++FF+PY+W L+ S++
Sbjct: 602 -RVLEIIKQGVVALPK-DRLKKFPELKFKYVEEEQPEEFFIPYVWSLVYNSAV 652
>sp|Q8CHY3|DYM_MOUSE Dymeclin
Length = 669
Score = 172 bits (437), Expect = 7e-43
Identities = 89/231 (38%), Positives = 159/231 (68%), Gaps = 4/231 (1%)
Frame = +2
Query: 35 NEKTITNISIGSLIVWILCRTIQFNFGHVGDRYIHINCLAALANMSSKFINLHPLASEQI 214
+E+ +T IS+GSL++ ++ RTIQ+N D+Y+H NCLAALANMS++F +LH A+++I
Sbjct: 426 SERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRI 485
Query: 215 MILLNILLKR--KV--YLSNNLKNITENQDSEKFSNLSNNLSVIEEIIQMLVEIVNTALI 382
+ L ++L K+ KV + +L+ + D + + +LSVIEE+I+M++EI+N+ L
Sbjct: 486 ISLFSLLSKKHNKVLEQATQSLRGPLSSSD-VPLPDYAQDLSVIEEVIRMMLEIINSCLT 544
Query: 383 FSLNNNPHMIHTFLYHKKLFSQMKINSHTETHLCNIDAILTYFSSKIEKELGKSVSSQNE 562
SL++NP++++ LY + LF Q + + + + NID ++++FSS++ + G +S +
Sbjct: 545 NSLHHNPNLVYALLYKRDLFEQFRTHPSFQDIMQNIDLVISFFSSRL-LQAGAELSVE-R 602
Query: 563 VLKVIKKFSPSINKLNNFKRFPELKFKYIEQESSDDFFVPYIWRLICKSSL 715
VL++IK+ ++ K + K+FPELKFKY+E+E ++FF+PY+W L+ S++
Sbjct: 603 VLEIIKQGVVALPK-DRLKKFPELKFKYVEEEQPEEFFIPYVWSLVYNSAV 652
>sp|Q7RTS9|DYM_HUMAN Dymeclin (Dyggve-Melchior-Clausen syndrome protein)
Length = 669
Score = 172 bits (437), Expect = 7e-43
Identities = 88/233 (37%), Positives = 158/233 (67%), Gaps = 6/233 (2%)
Frame = +2
Query: 35 NEKTITNISIGSLIVWILCRTIQFNFGHVGDRYIHINCLAALANMSSKFINLHPLASEQI 214
+E+ +T IS+GSL++ ++ RTIQ+N D+Y+H NCLAALANMS++F +LH A+++I
Sbjct: 426 SERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRI 485
Query: 215 MILLNILLKRKVYLSNNLKNITENQDSEKFSN------LSNNLSVIEEIIQMLVEIVNTA 376
+ L ++L K+ + L+ T++ SN + +L+VIEE+I+M++EI+N+
Sbjct: 486 ISLFSLLSKKH---NKVLEQATQSLRGSLSSNDVPLPDYAQDLNVIEEVIRMMLEIINSC 542
Query: 377 LIFSLNNNPHMIHTFLYHKKLFSQMKINSHTETHLCNIDAILTYFSSKIEKELGKSVSSQ 556
L SL++NP++++ LY + LF Q + + + + NID ++++FSS++ + G +S +
Sbjct: 543 LTNSLHHNPNLVYALLYKRDLFEQFRTHPSFQDIMQNIDLVISFFSSRL-LQAGAELSVE 601
Query: 557 NEVLKVIKKFSPSINKLNNFKRFPELKFKYIEQESSDDFFVPYIWRLICKSSL 715
VL++IK+ ++ K + K+FPELKFKY+E+E ++FF+PY+W L+ S++
Sbjct: 602 -RVLEIIKQGVVALPK-DRLKKFPELKFKYVEEEQPEEFFIPYVWSLVYNSAV 652
>sp|Q8M355|RMAR_SACCA Mitochondrial ribosomal protein VAR1
Length = 326
Score = 35.8 bits (81), Expect = 0.14
Identities = 32/168 (19%), Positives = 85/168 (50%), Gaps = 6/168 (3%)
Frame = +2
Query: 35 NEKTITNISIGSLIVWILCRTIQFNFGHVGDRYIHINCLAALANMSS---KFINLHPLAS 205
N N+ + ++++ + N + +Y++ N L ++ NM++ + N +
Sbjct: 10 NNNNNKNMLLKNMLLKMNINNNNMNTNNNNMKYMN-NKLQSINNMNNWSLQMYNYNKNNE 68
Query: 206 EQIMILLNILLKRKVYLSNNL--KNITENQDSEKFSNLSNNLSVIEEIIQMLVEIVNTAL 379
+M+++N++ K L N + N+T N +++ +NN+ +++ + Q ++ +N
Sbjct: 69 LNMMMMMNMMNKLLYKLMNMIMINNMTMNVNNKN----NNNIIMMKPMYQYMMNKLNIKF 124
Query: 380 IFSLNNNPHMIHTFLYHKKLFSQMK-INSHTETHLCNIDAILTYFSSK 520
+ +NNN ++T Y L+ M +N++ ++ N++ I++ + +K
Sbjct: 125 YYYINNN--NMNTNYYMNMLYKLMNTLNNNNNMYMNNMNNIMSMYINK 170
>sp|P57091|C18BA_PAEPP Parasporal crystal protein cry18Ba (Parasporal delta-endotoxin
CryXVIIIB(a)) (Crystaline parasporal protoxin) (76 kDa
crystal protein)
Length = 675
Score = 34.7 bits (78), Expect = 0.31
Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 4/59 (6%)
Frame = +2
Query: 230 ILLKRKVYLSNNLKNITENQDSEKFSNLSNNLSV----IEEIIQMLVEIVNTALIFSLN 394
IL + Y+ L +T N+ S++ L NNL I++ +Q VEI TA+I S+N
Sbjct: 121 ILRATEQYVQEQLDTVTWNRVSQELEGLKNNLRTFNDQIDDFLQNRVEISPTAMIDSIN 179
>sp||Q9NZ56_2 [Segment 2 of 2] Formin-2
Length = 297
Score = 34.3 bits (77), Expect = 0.40
Identities = 28/126 (22%), Positives = 59/126 (46%), Gaps = 6/126 (4%)
Frame = +2
Query: 299 KFSNLSNNLSVIEEIIQMLVEIVNTALIFSLNNNPHM------IHTFLYHKKLFSQMKIN 460
KF + +L +++ ++ V ++ +++ HM + F+ K+ + + N
Sbjct: 147 KFEDFQKDLRKLKKDLKACE--VEAGKVYQVSSKEHMQPFKENMEQFIIQAKIDQEAEEN 204
Query: 461 SHTETHLCNIDAILTYFSSKIEKELGKSVSSQNEVLKVIKKFSPSINKLNNFKRFPELKF 640
S TETH C ++ +F ++ +LG+ S N + +FS ++FK F + +
Sbjct: 205 SLTETHKCFLETTAYFF---MKPKLGEKEVSPNAFFSIWHEFS------SDFKDFWKKEN 255
Query: 641 KYIEQE 658
K + QE
Sbjct: 256 KLLLQE 261
>sp|O35161|CELR1_MOUSE Cadherin EGF LAG seven-pass G-type receptor 1 precursor
Length = 3034
Score = 33.9 bits (76), Expect = 0.53
Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 4/63 (6%)
Frame = +2
Query: 341 IIQMLVEIVNTALIFSLNNNPHMIHTFLYHKKLFSQM----KINSHTETHLCNIDAILTY 508
++ +LV V +L+ +L +N H IH L FSQ+ IN LC + AIL +
Sbjct: 2495 LVALLVAFVLLSLVRTLRSNLHSIHKNLIAALFFSQLIFMVGINQTENPFLCTVVAILLH 2554
Query: 509 FSS 517
+ S
Sbjct: 2555 YVS 2557
>sp|P20103|NISB_LACLA Nisin biosynthesis protein nisB
Length = 993
Score = 33.1 bits (74), Expect = 0.90
Identities = 51/183 (27%), Positives = 77/183 (42%), Gaps = 9/183 (4%)
Frame = +2
Query: 179 FINLHPLASEQIMILLNILLKRKVYLSNNLKNITENQDSEKFSNLSNNLSVIEEIIQMLV 358
F+NL + I IL +I+ +NNL S +FS LS L+ I V
Sbjct: 435 FLNLAKEYEKDIFILGDIVG------NNNLGGA-----SGRFSALSPELTSYHRTIVDSV 483
Query: 359 E-------IVNTALIFSLNNNPH--MIHTFLYHKKLFSQMKINSHTETHLCNIDAILTYF 511
E I + ++F N H ++HT + +K+ SH E L NI +
Sbjct: 484 ERENENKEITSCEIVFLPENIRHANVMHTSIMRRKVLPFFTSTSHNEVLLTNIYIGI--- 540
Query: 512 SSKIEKELGKSVSSQNEVLKVIKKFSPSINKLNNFKRFPELKFKYIEQESSDDFFVPYIW 691
+ EK + +S+Q +V+K + S+ F EL+F Y + S DD F W
Sbjct: 541 -DEKEKFYARDISTQ----EVLKFYITSMYNKTLFSN--ELRFLY--EISLDDKFGNLPW 591
Query: 692 RLI 700
LI
Sbjct: 592 ELI 594
>sp|P36626|REC8_SCHPO Meiotic recombination protein rec8 (Cohesin rec8)
Length = 561
Score = 33.1 bits (74), Expect = 0.90
Identities = 33/135 (24%), Positives = 62/135 (45%), Gaps = 9/135 (6%)
Frame = +2
Query: 50 TNISIGSLIVWILCRTIQFNFGHVGDRYIHINCLAALANMSSKFINLHPLASEQI---MI 220
+N+ IG VW Q++F H +H+ L + +SK + +EQ +
Sbjct: 63 SNLMIGVTRVW----AHQYSFFHSQVSTLHLRVRKELDHFTSKPFKNIDIQNEQTNPKQL 118
Query: 221 LLN----ILLKRKVYLSNNLKNITENQDSEKFSNLSNN--LSVIEEIIQMLVEIVNTALI 382
LL + + +Y + NL ++ + D F+ N +SV+E + ++NT+
Sbjct: 119 LLAEDPAFIPEVSLYDAFNLPSVDLHVDMSSFTQPKENPNISVLETLPDSTSYLINTSQN 178
Query: 383 FSLNNNPHMIHTFLY 427
+SL NN + +F+Y
Sbjct: 179 YSLRNN---VSSFVY 190
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,971,104
Number of Sequences: 369166
Number of extensions: 1325707
Number of successful extensions: 4004
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3847
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3991
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7522142940
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)