Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_006_C05
(898 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P32369|BAIG_EUBSP Bile acid transporter 51 4e-06
sp|P37643|YHJE_ECOLI Inner membrane metabolite transport pr... 50 7e-06
sp|Q92EE1|LMRB_LISIN Lincomycin resistance protein lmrB 49 1e-05
sp|Q8Y9K8|LMRB_LISMO Lincomycin resistance protein lmrB 49 1e-05
sp|Q58955|YF60_METJA Putative transporter MJ1560 49 1e-05
sp|P46907|NARK_BACSU Nitrite extrusion protein (Nitrite fac... 47 9e-05
sp|P47234|LACY_CITFR Lactose permease (Lactose-proton symport) 46 2e-04
sp|P58120|PMRA_LACLA Multi-drug resistance efflux pump pmrA... 42 0.002
sp|P25744|MDTG_ECOLI Multidrug resistance protein mdtG >gi|... 42 0.002
sp|P46333|CSBC_BACSU Probable metabolite transport protein ... 42 0.003
>sp|P32369|BAIG_EUBSP Bile acid transporter
Length = 477
Score = 51.2 bits (121), Expect = 4e-06
Identities = 33/144 (22%), Positives = 67/144 (46%), Gaps = 1/144 (0%)
Frame = +3
Query: 453 GLNGADAALITSLLYIVSAACSPVMGFLIDLTGRNLFWVLTGTLATLGS-HALYAFTFAN 629
G++ + I+ L + SAAC+P++G L D+ GR +L + G+ A +
Sbjct: 42 GIDYNNTTWISLALAMSSAACAPILGKLGDVLGRRTTLLLGIVIFAAGNVLTAVATSLIF 101
Query: 630 PLGVMIFLGVSYSVLASSLWPMVALVIPAHQRGTAFGIMQSVQNLGLAVVAIIAGLIQDK 809
L +G+ + ++ + + P + G AFG+ + + + V GLI +
Sbjct: 102 MLAARFIVGIGTAAISPIVMAYIVTEYPQEETGKAFGLYMLISSGAVVVGPTCGGLIMNA 161
Query: 810 YGFLILEVFFSVWLCITLVLIVLL 881
G+ ++ +W+C+ L ++V L
Sbjct: 162 AGWRVM-----MWVCVALCVVVFL 180
>sp|P37643|YHJE_ECOLI Inner membrane metabolite transport protein yhjE
Length = 440
Score = 50.4 bits (119), Expect = 7e-06
Identities = 53/212 (25%), Positives = 89/212 (41%), Gaps = 13/212 (6%)
Frame = +3
Query: 288 ILQRNKKNSEDEKISLGDI--RHFSVAF---WIISGICVAYYVAVFPFVSLSKVFLIQKY 452
+ ++ K + KI LG + +H V +I+ +Y+ ++ S
Sbjct: 224 VFEKVAKAKKQVKIPLGTLLTKHVRVTVLGTFIMLATYTLFYIMTVYSMTFSTAAAPVGL 283
Query: 453 GLNGADAALITSLLYIVSAACSPVMGFLIDLTGRNLFWVLTGTLATLGSHALYAFT---- 620
GL + + + I PV G L D GR V+ TL L AL+AF
Sbjct: 284 GLPRNEVLWMLMMAVIGFGVMVPVAGLLADAFGRRKSMVIITTLIIL--FALFAFNPLLG 341
Query: 621 FANPLGVMIFLGVSYSVLASSLWPMVALV---IPAHQRGTAFGIMQSVQN-LGLAVVAII 788
NP+ V FL + S++ + PM AL+ P R T +V + LG +V I
Sbjct: 342 SGNPILVFAFLLLGLSLMGLTFGPMGALLPELFPTEVRYTGASFSYNVASILGASVAPYI 401
Query: 789 AGLIQDKYGFLILEVFFSVWLCITLVLIVLLY 884
A +Q YG + ++ + +TL+ ++L +
Sbjct: 402 AAWLQTNYGLGAVGLYLAAMAGLTLIALLLTH 433
>sp|Q92EE1|LMRB_LISIN Lincomycin resistance protein lmrB
Length = 471
Score = 49.3 bits (116), Expect = 1e-05
Identities = 45/180 (25%), Positives = 83/180 (46%), Gaps = 8/180 (4%)
Frame = +3
Query: 369 IISGICVAYYVAVFPFVSLSKVF--LIQKYGLNGADAALITSLLYIVSAACSPVMGFLID 542
II+ +A ++ +F +L+ LIQ + ++ A +T+ + P+ G L+
Sbjct: 16 IIASFLMAGFIGLFSETALNMALSDLIQVFDISSATVQWLTTGYLLTLGILVPISGLLLQ 75
Query: 543 -LTGRNLFWV-----LTGTLATLGSHALYAFTFANPLGVMIFLGVSYSVLASSLWPMVAL 704
T R LF+ + GTL A + TFA + + V ++L ++ + L
Sbjct: 76 WFTTRGLFFTAVSFSIAGTLI-----AALSPTFAMLMIGRVVQAVGTALLLPLMFNTILL 130
Query: 705 VIPAHQRGTAFGIMQSVQNLGLAVVAIIAGLIQDKYGFLILEVFFSVWLCITLVLIVLLY 884
+ P H+RG+A G++ V AV I+GLI + L + W+ + ++I LL+
Sbjct: 131 IFPEHKRGSAMGMIGLVIMFAPAVGPTISGLILEN-----LTWNWIFWISLPFLIIALLF 185
>sp|Q8Y9K8|LMRB_LISMO Lincomycin resistance protein lmrB
Length = 471
Score = 49.3 bits (116), Expect = 1e-05
Identities = 45/180 (25%), Positives = 83/180 (46%), Gaps = 8/180 (4%)
Frame = +3
Query: 369 IISGICVAYYVAVFPFVSLSKVF--LIQKYGLNGADAALITSLLYIVSAACSPVMGFLID 542
II+ +A ++ +F +L+ LIQ + ++ A +T+ + P+ G L+
Sbjct: 16 IIASFLMAGFIGLFSETALNMALSDLIQVFDISSATVQWLTTGYLLTLGILVPISGLLLQ 75
Query: 543 -LTGRNLFWV-----LTGTLATLGSHALYAFTFANPLGVMIFLGVSYSVLASSLWPMVAL 704
T R LF+ + GTL A + TFA + + V ++L ++ + L
Sbjct: 76 WFTTRGLFFTAVSFSIAGTLI-----AALSPTFAMLMIGRVVQAVGTALLLPLMFNTILL 130
Query: 705 VIPAHQRGTAFGIMQSVQNLGLAVVAIIAGLIQDKYGFLILEVFFSVWLCITLVLIVLLY 884
+ P H+RG+A G++ V AV I+GLI + L + W+ + ++I LL+
Sbjct: 131 IFPEHKRGSAMGMIGLVIMFAPAVGPTISGLILEN-----LTWNWIFWISLPFLIIALLF 185
>sp|Q58955|YF60_METJA Putative transporter MJ1560
Length = 386
Score = 49.3 bits (116), Expect = 1e-05
Identities = 49/227 (21%), Positives = 106/227 (46%), Gaps = 7/227 (3%)
Frame = +3
Query: 228 CVFSLICALVLAMFDRRAERILQRNKKNSEDEKIS------LGDIRHFSVAFWIISGICV 389
C F I A +++ + + + + +NK+ + +KIS R+FS +F II+ V
Sbjct: 166 CGFLGILAAIIS-YMKLEDIVFNKNKEKIDVKKISTLFSFEFLKNRNFSSSF-IINVSNV 223
Query: 390 AYYVAVFPFVSLSKVFLIQKYGLNGADAALITSLLYIVSAACSPVMGFLIDLTGRNLFWV 569
++ +++L + Y + + + +L I+ A G L D G N+ +
Sbjct: 224 MINAGIYAYLALYAI----NYNITISQVGFMIALTNILMALLQRSFGKLYDKLG-NIMII 278
Query: 570 LTGTLATLGSHALY-AFTFANPLGVMIFLGVSYSVLASSLWPMVALVIPAHQRGTAFGIM 746
+ + + G + L + TF L + + V S+ +++ + IP H++G A G+
Sbjct: 279 IGIFIISFGMYLLSTSTTFLTILASLTIIAVGSSISSTATTSLAVKDIPTHRKGEAMGLF 338
Query: 747 QSVQNLGLAVVAIIAGLIQDKYGFLILEVFFSVWLCITLVLIVLLYL 887
+ N+G+ + A+ G + D G + F +++ ++V+ ++ YL
Sbjct: 339 TTSINIGMFIGAVSFGFLADILGIANMYKFSAIF---SIVVGIISYL 382
>sp|P46907|NARK_BACSU Nitrite extrusion protein (Nitrite facilitator)
Length = 395
Score = 46.6 bits (109), Expect = 9e-05
Identities = 51/183 (27%), Positives = 80/183 (43%), Gaps = 10/183 (5%)
Frame = +3
Query: 366 WIISGICVAYYVAVFPFVSLSKVFLIQKYGLNGADAALITSLLYIVSAACSPVMGFLIDL 545
W +S + A F FL++ +GLN ADA L T+ VS P GFL D
Sbjct: 205 WFLSLFYFITFGAFVAFTIYLPNFLVEHFGLNPADAGLRTAGFIAVSTLLRPAGGFLADK 264
Query: 546 TG--RNLFWVLTGTLATLGSHALYAFTFANPLGVMIFLGVSYSVLASSLWPMVALVIP-- 713
R L +V TG TL L +F+ +G+ F ++ +V + V ++P
Sbjct: 265 MSPLRILMFVFTG--LTLSGIIL---SFSPTIGLYTFGSLTVAVCSGIGNGTVFKLVPFY 319
Query: 714 -AHQRGTAFGIMQSVQNLG-----LAVVAIIAGLIQDKYGFLILEVFFSVWLCITLVLIV 875
+ Q G A GI+ ++ LG L + ++ Q GF+ L S + VL++
Sbjct: 320 FSKQAGIANGIVSAMGGLGGFFPPLILASVFQATGQYAIGFMAL----SEVALASFVLVI 375
Query: 876 LLY 884
+Y
Sbjct: 376 WMY 378
>sp|P47234|LACY_CITFR Lactose permease (Lactose-proton symport)
Length = 416
Score = 45.8 bits (107), Expect = 2e-04
Identities = 42/187 (22%), Positives = 80/187 (42%), Gaps = 13/187 (6%)
Frame = +3
Query: 363 FWIISGICVAYYVAVFPFVSLSKVFLIQKYGLNGADAALITSLLYIVSAACSPVMGFLID 542
FW+ Y+ + + ++L + ++ D +I + + + S P+ G L D
Sbjct: 9 FWMFGFFFFFYFFIMGAYFPFFPIWLHEVNHISKGDTGIIFACISLFSLLFQPIFGLLSD 68
Query: 543 LTG--RNLFWVLTGTLATLGSHALYAFTFANPLGVM-------IFLGVSYSVLASSLWPM 695
G ++L WV+TG L +Y F + ++ I+LG Y+ A ++
Sbjct: 69 KLGLRKHLLWVITGMLVMFAPFFIYVFGPLLQVNILLGSIVGGIYLGFIYNAGAPAI--- 125
Query: 696 VALVIPAHQRGT-AFGIMQSVQNLGLAVVAIIAGLIQDKYGFLILEVFFSVWL---CITL 863
A + A +R FG + +G A+ A IAG++ + F WL C +
Sbjct: 126 EAYIEKASRRSNFEFGRARMFGCVGWALCASIAGIM------FTINNQFVFWLGSGCAVI 179
Query: 864 VLIVLLY 884
+ ++LL+
Sbjct: 180 LALLLLF 186
>sp|P58120|PMRA_LACLA Multi-drug resistance efflux pump pmrA homolog
Length = 405
Score = 42.4 bits (98), Expect = 0.002
Identities = 42/178 (23%), Positives = 76/178 (42%), Gaps = 5/178 (2%)
Frame = +3
Query: 366 WIISGICVAYYVAVFPFVSLSKVFLIQKYGLNGADAALITSLLYIVSAACS----PVMGF 533
WI + + V PF+ L IQ G++G + L + L + + A S P+ G
Sbjct: 17 WIGCFFVGSSFSLVMPFLPL----YIQGLGVSGGNVELYSGLAFSLPALASGLVAPIWGR 72
Query: 534 LIDLTGRNLFWVLTGTLATLGSHAL-YAFTFANPLGVMIFLGVSYSVLASSLWPMVALVI 710
L D GR + V + TL + +A LG+ + +G + +S M+A
Sbjct: 73 LADEHGRKVMMVRASIVMTLTMGGIAFAPNVWWLLGLRLLMGFFSGYIPNST-AMIASQA 131
Query: 711 PAHQRGTAFGIMQSVQNLGLAVVAIIAGLIQDKYGFLILEVFFSVWLCITLVLIVLLY 884
P + G A G + + G + + GL+ + +G + VF V + L ++ ++
Sbjct: 132 PKDKSGYALGTLATAMVSGTLIGPSLGGLLAEWFG--MANVFLIVGALLALATLLTIF 187
>sp|P25744|MDTG_ECOLI Multidrug resistance protein mdtG
sp|Q8X9I3|MDTG_ECO57 Multidrug resistance protein mdtG
Length = 408
Score = 42.0 bits (97), Expect = 0.002
Identities = 45/185 (24%), Positives = 80/185 (43%), Gaps = 9/185 (4%)
Frame = +3
Query: 357 VAFWIISGICVAYYVAVFPFVSLSKVFLIQKYGLNGADA-----ALITSLLYIVSAACSP 521
+ W+ + A + V PF+ L +++ G+ G A ++ S+ ++ SA SP
Sbjct: 17 IVAWLGCFLTGAAFSLVMPFLPL----YVEQLGVTGHSALNMWSGIVFSITFLFSAIASP 72
Query: 522 VMGFLIDLTGRNLFWVLT----GTLATLGSHALYAFTFANPLGVMIFLGVSYSVLASSLW 689
G L D GR L + + G + L A + F ++ LG + A++L
Sbjct: 73 FWGGLADRKGRKLMLLRSALGMGIVMVLMGLAQNIWQFLILRALLGLLG-GFVPNANAL- 130
Query: 690 PMVALVIPAHQRGTAFGIMQSVQNLGLAVVAIIAGLIQDKYGFLILEVFFSVWLCITLVL 869
+A +P ++ G A G + + G + + GL+ D YG + VFF + L
Sbjct: 131 --IATQVPRNKSGWALGTLSTGGVSGALLGPMAGGLLADSYG--LRPVFFITASVLILCF 186
Query: 870 IVLLY 884
V L+
Sbjct: 187 FVTLF 191
>sp|P46333|CSBC_BACSU Probable metabolite transport protein csbC
Length = 461
Score = 41.6 bits (96), Expect = 0.003
Identities = 54/213 (25%), Positives = 92/213 (43%), Gaps = 23/213 (10%)
Frame = +3
Query: 288 ILQRNKKNSEDEKISLGDIRHFSVAFWIISGICVAYYVAVFP-FVSLSKVF-----LIQK 449
+ + + +E ++ +LG ++ A WI + + +A+F V ++ V + K
Sbjct: 216 LAEMKQGEAEKKETTLGVLK----AKWIRPMLLIGVGLAIFQQAVGINTVIYYAPTIFTK 271
Query: 450 YGLNGADAALITSLLYIVSAACSPVMGFLIDLTGRN--LFW----------VLTGTLATL 593
GL + +AL T + I++ LID GR L W L+G L TL
Sbjct: 272 AGLGTSASALGTMGIGILNVIMCITAMILIDRVGRKKLLIWGSVGITLSLAALSGVLLTL 331
Query: 594 GSHALYAFTFANPLGVMIFLGVSYSVLASSLWPMVALVI-----PAHQRGTAFGIMQSVQ 758
G A A+ ++FLGV Y V + W V V+ P+ RG A G V
Sbjct: 332 GLSASTAWM------TVVFLGV-YIVFYQATWGPVVWVLMPELFPSKARGAATGFTTLVL 384
Query: 759 NLGLAVVAIIAGLIQDKYGFLILEVFFSVWLCI 857
+ +V+++ L+ G + + FSV +C+
Sbjct: 385 SAANLIVSLVFPLMLSAMGIAWVFMVFSV-ICL 416
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102,551,026
Number of Sequences: 369166
Number of extensions: 2054205
Number of successful extensions: 6612
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6311
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6598
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9030416440
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)