Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_006_B04
(494 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P41570|6PGD_CERCA 6-phosphogluconate dehydrogenase, deca... 202 3e-52
sp|P41572|6PGD_DROME 6-phosphogluconate dehydrogenase, deca... 199 4e-51
sp|P41573|6PGD_DROSI 6-phosphogluconate dehydrogenase, deca... 199 4e-51
sp|O60037|6PGD_CUNEL 6-phosphogluconate dehydrogenase, deca... 194 1e-49
sp|Q9DCD0|6PGD_MOUSE 6-phosphogluconate dehydrogenase, deca... 194 1e-49
sp|Q17761|6PGD_CAEEL 6-phosphogluconate dehydrogenase, deca... 192 5e-49
sp|P52209|6PGD_HUMAN 6-phosphogluconate dehydrogenase, deca... 189 3e-48
sp|P00349|6PGD_SHEEP 6-phosphogluconate dehydrogenase, deca... 189 4e-48
sp|P14332|6PGD_PIG 6-phosphogluconate dehydrogenase, decarb... 180 1e-45
sp|P53319|6PGD2_YEAST 6-phosphogluconate dehydrogenase, dec... 176 3e-44
>sp|P41570|6PGD_CERCA 6-phosphogluconate dehydrogenase, decarboxylating
Length = 481
Score = 202 bits (515), Expect = 3e-52
Identities = 100/149 (67%), Positives = 112/149 (75%)
Frame = +1
Query: 1 YTQGFMMMKSASHEFKWNLDLGKIALMWRGGCIIRSRFLQNIKDAYEKNKNLSILLFDKF 180
Y QGFM+M+ A+ E WNL+ G IALMWRGGCIIRS FL NIKDAY +N LS LL D F
Sbjct: 333 YAQGFMLMREAAKENNWNLNYGGIALMWRGGCIIRSVFLGNIKDAYTRNPQLSNLLLDDF 392
Query: 181 FQSEILKCQESWRHVVANAALHGIPTPAFSCALAFYDGLRTEKLPANLIQAQRDLFGAHQ 360
F+ I Q SWR VVANA L GIP PA S AL+FYDG RTEKLPANL+QAQRD FGAH
Sbjct: 393 FKKAIEVGQNSWRQVVANAFLWGIPVPALSTALSFYDGYRTEKLPANLLQAQRDYFGAHT 452
Query: 361 YQLLDHPGTYEHTDWTGHGGNAAASTYQA 447
Y+LL G + HT+WTG GGN +ASTYQA
Sbjct: 453 YELLGAEGKFVHTNWTGTGGNVSASTYQA 481
>sp|P41572|6PGD_DROME 6-phosphogluconate dehydrogenase, decarboxylating
Length = 481
Score = 199 bits (505), Expect = 4e-51
Identities = 97/149 (65%), Positives = 110/149 (73%)
Frame = +1
Query: 1 YTQGFMMMKSASHEFKWNLDLGKIALMWRGGCIIRSRFLQNIKDAYEKNKNLSILLFDKF 180
Y QGFM+M+ A+ E KW L+ G IALMWRGGCIIRS FL NIKDAY LS LL D F
Sbjct: 333 YAQGFMLMREAARENKWRLNYGGIALMWRGGCIIRSVFLGNIKDAYTSQPELSNLLLDDF 392
Query: 181 FQSEILKCQESWRHVVANAALHGIPTPAFSCALAFYDGLRTEKLPANLIQAQRDLFGAHQ 360
F+ I + Q+SWR VVANA GIP PA S AL+FYDG RT KLPANL+QAQRD FGAH
Sbjct: 393 FKKAIERGQDSWREVVANAFRWGIPVPALSTALSFYDGYRTAKLPANLLQAQRDYFGAHT 452
Query: 361 YQLLDHPGTYEHTDWTGHGGNAAASTYQA 447
Y+LL G + HT+WTG GGN +ASTYQA
Sbjct: 453 YELLGQEGQFHHTNWTGTGGNVSASTYQA 481
>sp|P41573|6PGD_DROSI 6-phosphogluconate dehydrogenase, decarboxylating
Length = 481
Score = 199 bits (505), Expect = 4e-51
Identities = 97/149 (65%), Positives = 110/149 (73%)
Frame = +1
Query: 1 YTQGFMMMKSASHEFKWNLDLGKIALMWRGGCIIRSRFLQNIKDAYEKNKNLSILLFDKF 180
Y QGFM+M+ A+ E KW L+ G IALMWRGGCIIRS FL NIKDAY LS LL D F
Sbjct: 333 YAQGFMLMREAARENKWRLNYGGIALMWRGGCIIRSVFLGNIKDAYTSQPQLSNLLLDDF 392
Query: 181 FQSEILKCQESWRHVVANAALHGIPTPAFSCALAFYDGLRTEKLPANLIQAQRDLFGAHQ 360
F+ I + Q+SWR VVANA GIP PA S AL+FYDG RT KLPANL+QAQRD FGAH
Sbjct: 393 FKKAIERGQDSWREVVANAFRWGIPVPALSTALSFYDGYRTAKLPANLLQAQRDYFGAHT 452
Query: 361 YQLLDHPGTYEHTDWTGHGGNAAASTYQA 447
Y+LL G + HT+WTG GGN +ASTYQA
Sbjct: 453 YELLGQEGQFHHTNWTGTGGNVSASTYQA 481
>sp|O60037|6PGD_CUNEL 6-phosphogluconate dehydrogenase, decarboxylating
Length = 485
Score = 194 bits (493), Expect = 1e-49
Identities = 92/149 (61%), Positives = 110/149 (73%)
Frame = +1
Query: 1 YTQGFMMMKSASHEFKWNLDLGKIALMWRGGCIIRSRFLQNIKDAYEKNKNLSILLFDKF 180
Y QG+M+M+ A+ +++W L+ IALMWRGGCIIRS FL I+DAY KN L LLFD F
Sbjct: 337 YAQGYMLMRQAAKDYEWKLNNAGIALMWRGGCIIRSVFLGKIRDAYTKNPELENLLFDDF 396
Query: 181 FQSEILKCQESWRHVVANAALHGIPTPAFSCALAFYDGLRTEKLPANLIQAQRDLFGAHQ 360
F+ K Q++WR+V A A L GIPTPA S AL FYDGLR E LPANL+QAQRD FGAH
Sbjct: 397 FKDATAKAQDAWRNVTAQAVLMGIPTPALSTALNFYDGLRHEILPANLLQAQRDYFGAHT 456
Query: 361 YQLLDHPGTYEHTDWTGHGGNAAASTYQA 447
Y+LL PG + HT+WTG GGN +ASTY A
Sbjct: 457 YELLHTPGKWVHTNWTGRGGNVSASTYDA 485
>sp|Q9DCD0|6PGD_MOUSE 6-phosphogluconate dehydrogenase, decarboxylating
Length = 483
Score = 194 bits (492), Expect = 1e-49
Identities = 89/149 (59%), Positives = 110/149 (73%)
Frame = +1
Query: 1 YTQGFMMMKSASHEFKWNLDLGKIALMWRGGCIIRSRFLQNIKDAYEKNKNLSILLFDKF 180
Y QGFM+++ A+ EF W L+ G IALMWRGGCIIRS FL IKDA+E+N L LL D F
Sbjct: 335 YAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFERNPELQNLLLDDF 394
Query: 181 FQSEILKCQESWRHVVANAALHGIPTPAFSCALAFYDGLRTEKLPANLIQAQRDLFGAHQ 360
F+S + CQ+SWR V++ GIP P F+ AL+FYDG R E LPANLIQAQRD FGAH
Sbjct: 395 FKSAVDNCQDSWRRVISTGVQAGIPMPCFTTALSFYDGYRHEMLPANLIQAQRDYFGAHT 454
Query: 361 YQLLDHPGTYEHTDWTGHGGNAAASTYQA 447
Y+LL PG + HT+WTGHGG+ ++S+Y A
Sbjct: 455 YELLTKPGEFIHTNWTGHGGSVSSSSYNA 483
>sp|Q17761|6PGD_CAEEL 6-phosphogluconate dehydrogenase, decarboxylating
Length = 484
Score = 192 bits (487), Expect = 5e-49
Identities = 91/149 (61%), Positives = 109/149 (73%)
Frame = +1
Query: 1 YTQGFMMMKSASHEFKWNLDLGKIALMWRGGCIIRSRFLQNIKDAYEKNKNLSILLFDKF 180
Y QGFM++ AS +F WNL+ G IALMWRGGCIIRSRFL +I+ A++KNK LS LL D F
Sbjct: 336 YAQGFMLLAEASKQFNWNLNFGAIALMWRGGCIIRSRFLGDIEHAFQKNKQLSNLLLDDF 395
Query: 181 FQSEILKCQESWRHVVANAALHGIPTPAFSCALAFYDGLRTEKLPANLIQAQRDLFGAHQ 360
F I + Q+SWR VV A GIP PAFS ALAFYDG +E +PANL+QAQRD FGAH
Sbjct: 396 FTKAITEAQDSWRVVVCAAVRLGIPVPAFSSALAFYDGYTSEVVPANLLQAQRDYFGAHT 455
Query: 361 YQLLDHPGTYEHTDWTGHGGNAAASTYQA 447
Y+LL PGT+ HT+WTG GG ++ Y A
Sbjct: 456 YELLAKPGTWVHTNWTGTGGRVTSNAYNA 484
>sp|P52209|6PGD_HUMAN 6-phosphogluconate dehydrogenase, decarboxylating
Length = 483
Score = 189 bits (480), Expect = 3e-48
Identities = 87/149 (58%), Positives = 108/149 (72%)
Frame = +1
Query: 1 YTQGFMMMKSASHEFKWNLDLGKIALMWRGGCIIRSRFLQNIKDAYEKNKNLSILLFDKF 180
Y QGFM+++ A+ EF W L+ G IALMWRGGCIIRS FL IKDA+++N L LL D F
Sbjct: 335 YAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDF 394
Query: 181 FQSEILKCQESWRHVVANAALHGIPTPAFSCALAFYDGLRTEKLPANLIQAQRDLFGAHQ 360
F+S + CQ+SWR V+ GIP P F+ AL+FYDG R E LPA+LIQAQRD FGAH
Sbjct: 395 FKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHT 454
Query: 361 YQLLDHPGTYEHTDWTGHGGNAAASTYQA 447
Y+LL PG + HT+WTGHGG ++S+Y A
Sbjct: 455 YELLAKPGQFIHTNWTGHGGTVSSSSYNA 483
>sp|P00349|6PGD_SHEEP 6-phosphogluconate dehydrogenase, decarboxylating
Length = 483
Score = 189 bits (479), Expect = 4e-48
Identities = 86/149 (57%), Positives = 108/149 (72%)
Frame = +1
Query: 1 YTQGFMMMKSASHEFKWNLDLGKIALMWRGGCIIRSRFLQNIKDAYEKNKNLSILLFDKF 180
Y QGFM+++ A+ EF W L+ G IALMWRGGCIIRS FL IKDA+++N L LL D F
Sbjct: 335 YAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPGLQNLLLDDF 394
Query: 181 FQSEILKCQESWRHVVANAALHGIPTPAFSCALAFYDGLRTEKLPANLIQAQRDLFGAHQ 360
F+S + CQ+SWR ++ GIP P F+ AL+FYDG R LPANLIQAQRD FGAH
Sbjct: 395 FKSAVENCQDSWRRAISTGVQAGIPMPCFTTALSFYDGYRHAMLPANLIQAQRDYFGAHT 454
Query: 361 YQLLDHPGTYEHTDWTGHGGNAAASTYQA 447
Y+LL PG + HT+WTGHGG+ ++S+Y A
Sbjct: 455 YELLAKPGQFIHTNWTGHGGSVSSSSYNA 483
>sp|P14332|6PGD_PIG 6-phosphogluconate dehydrogenase, decarboxylating
Length = 250
Score = 180 bits (457), Expect = 1e-45
Identities = 85/149 (57%), Positives = 107/149 (71%)
Frame = +1
Query: 1 YTQGFMMMKSASHEFKWNLDLGKIALMWRGGCIIRSRFLQNIKDAYEKNKNLSILLFDKF 180
YTQGFM+++ A+ EF W+ + LMWRGGCIIRS FL IKDA+++N L LL D F
Sbjct: 103 YTQGFMLLRQAAAEFGWS-STTEHRLMWRGGCIIRSVFLGKIKDAFDRNPGLQNLLLDDF 161
Query: 181 FQSEILKCQESWRHVVANAALHGIPTPAFSCALAFYDGLRTEKLPANLIQAQRDLFGAHQ 360
F+S + CQ+SWR V+ GIP P F+ AL+FYDG R E LPANLIQAQRD FGAH
Sbjct: 162 FKSAVEDCQDSWRRAVSTGVQTGIPMPCFTTALSFYDGYRHEMLPANLIQAQRDYFGAHT 221
Query: 361 YQLLDHPGTYEHTDWTGHGGNAAASTYQA 447
Y+LL PG + HT+WTGHGG+ ++S+Y A
Sbjct: 222 YELLAKPGHFVHTNWTGHGGSVSSSSYNA 250
>sp|P53319|6PGD2_YEAST 6-phosphogluconate dehydrogenase, decarboxylating 2
Length = 492
Score = 176 bits (446), Expect = 3e-44
Identities = 85/156 (54%), Positives = 108/156 (69%), Gaps = 7/156 (4%)
Frame = +1
Query: 1 YTQGFMMMKSASHEFKWNLDLGKIALMWRGGCIIRSRFLQNIKDAYEKNKNLSILLFDKF 180
Y QGFM+++ A+ + W L+ IALMWRGGCIIRS FL I AY + +L LLF++F
Sbjct: 337 YAQGFMLIREAARSYGWKLNNPAIALMWRGGCIIRSVFLAEITKAYRDDPDLENLLFNEF 396
Query: 181 FQSEILKCQESWRHVVANAALHGIPTPAFSCALAFYDGLRTEKLPANLIQAQRDLFGAHQ 360
F S + K Q WR +A AA +GIPTPAFS ALAFYDG R+E+LPANL+QAQRD FGAH
Sbjct: 397 FASAVTKAQSGWRRTIALAATYGIPTPAFSTALAFYDGYRSERLPANLLQAQRDYFGAHT 456
Query: 361 YQLLDHPGTYE-------HTDWTGHGGNAAASTYQA 447
+++L + H +WTGHGGN ++STYQA
Sbjct: 457 FRILPECASAHLPVDKDIHINWTGHGGNISSSTYQA 492
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,795,111
Number of Sequences: 369166
Number of extensions: 1260909
Number of successful extensions: 3307
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3216
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3286
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 3069744620
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)