Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_006_A13 (718 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q16974|KPC1_APLCA Calcium-dependent protein kinase C (AP... 402 e-112 sp|P05130|KPC1_DROME Protein kinase C, brain isozyme (PKC) ... 394 e-109 sp|P68403|KPCB_RAT Protein kinase C, beta type (PKC-beta) (... 389 e-108 sp|P05771|KPCB_HUMAN Protein kinase C, beta type (PKC-beta)... 389 e-108 sp|P05772|KPCB_RABIT Protein kinase C, beta type (PKC-beta)... 387 e-107 sp|P04409|KPCA_BOVIN Protein kinase C, alpha type (PKC-alph... 382 e-106 sp|P05696|KPCA_RAT Protein kinase C, alpha type (PKC-alpha)... 382 e-106 sp|P17252|KPCA_HUMAN Protein kinase C, alpha type (PKC-alph... 382 e-106 sp|P10102|KPCA_RABIT Protein kinase C, alpha type (PKC-alph... 382 e-106 sp|P20444|KPCA_MOUSE Protein kinase C, alpha type (PKC-alph... 378 e-105
>sp|Q16974|KPC1_APLCA Calcium-dependent protein kinase C (APL I) Length = 649 Score = 402 bits (1032), Expect = e-112 Identities = 180/231 (77%), Positives = 213/231 (92%) Frame = +3 Query: 24 VQLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAVFYAAEIAVGLIFLHNHGII 203 VQLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVA FYAAEIA+GL +LH GI+ Sbjct: 382 VQLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAAFYAAEIAIGLFYLHTQGIV 441 Query: 204 YRDLKLDNVLLDSEGHIKIADFGMCKENIIGNATTKTFCGTPDYIAPEIIKYQPYGKSVD 383 YRDLKLDNV+LD+EGHIKIADFGMCKENI+G+ TT+TFCGTPDYIAPEI+ YQPYG+SVD Sbjct: 442 YRDLKLDNVMLDAEGHIKIADFGMCKENIMGDKTTRTFCGTPDYIAPEIVLYQPYGRSVD 501 Query: 384 WWAFGVLLYEMLAGQPPFDGEDEEDLFNSITNHNVSFPRSMSKEAVNVCRGLMTKDVNKR 563 WWA+GVLLYEMLAGQPPFDGEDEE+LF SIT+HNVS+P+++S+EAV++C+GL+TK KR Sbjct: 502 WWAYGVLLYEMLAGQPPFDGEDEEELFTSITDHNVSYPKALSREAVSLCKGLLTKTPAKR 561 Query: 564 LGCGVNGVRQIQEHVFFRRIEWDKIELREIQPPYKPKFKNKRDVSNFDKLF 716 LGCG NG R I++ FFR I+W++IELRE+QPPYKP+ K+++DVSNFD+ F Sbjct: 562 LGCGPNGERDIKDRAFFRPIQWERIELREVQPPYKPRIKSRKDVSNFDREF 612
>sp|P05130|KPC1_DROME Protein kinase C, brain isozyme (PKC) (dPKC53E(BR)) Length = 679 Score = 394 bits (1011), Expect = e-109 Identities = 179/231 (77%), Positives = 207/231 (89%) Frame = +3 Query: 24 VQLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAVFYAAEIAVGLIFLHNHGII 203 VQLHSCFQTMDRL+FVMEYVNGGDLM++IQQ GKFKEPVAVFYAAEIA GL FLH GI+ Sbjct: 412 VQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHTKGIL 471 Query: 204 YRDLKLDNVLLDSEGHIKIADFGMCKENIIGNATTKTFCGTPDYIAPEIIKYQPYGKSVD 383 YRDLKLDNVLLD++GH+KIADFGMCKENI+G+ TTKTFCGTPDYIAPEII YQPYGKSVD Sbjct: 472 YRDLKLDNVLLDADGHVKIADFGMCKENIVGDKTTKTFCGTPDYIAPEIILYQPYGKSVD 531 Query: 384 WWAFGVLLYEMLAGQPPFDGEDEEDLFNSITNHNVSFPRSMSKEAVNVCRGLMTKDVNKR 563 WWA+GVLLYEML GQPPFDGEDEE+LF +IT+HNVS+P+S+SKEA C+G +TK NKR Sbjct: 532 WWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAKEACKGFLTKQPNKR 591 Query: 564 LGCGVNGVRQIQEHVFFRRIEWDKIELREIQPPYKPKFKNKRDVSNFDKLF 716 LGCG +G ++ H FFRRI+W+KIE RE+QPP+KPK K+++DVSNFDK F Sbjct: 592 LGCGSSGEEDVRLHPFFRRIDWEKIENREVQPPFKPKIKHRKDVSNFDKQF 642
>sp|P68403|KPCB_RAT Protein kinase C, beta type (PKC-beta) (PKC-B) Length = 671 Score = 389 bits (998), Expect = e-108 Identities = 182/230 (79%), Positives = 201/230 (87%) Frame = +3 Query: 27 QLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAVFYAAEIAVGLIFLHNHGIIY 206 QLHSCFQTMDRLYFVMEYVNGGDLMY IQQ G+FKEP AVFYAAEIA+GL FL + GIIY Sbjct: 405 QLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIY 464 Query: 207 RDLKLDNVLLDSEGHIKIADFGMCKENIIGNATTKTFCGTPDYIAPEIIKYQPYGKSVDW 386 RDLKLDNV+LDSEGHIKIADFGMCKENI TTKTFCGTPDYIAPEII YQPYGKSVDW Sbjct: 465 RDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDW 524 Query: 387 WAFGVLLYEMLAGQPPFDGEDEEDLFNSITNHNVSFPRSMSKEAVNVCRGLMTKDVNKRL 566 WAFGVLLYEMLAGQ PF+GEDE++LF SI HNV++P+SMSKEAV +C+GLMTK KRL Sbjct: 525 WAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRL 584 Query: 567 GCGVNGVRQIQEHVFFRRIEWDKIELREIQPPYKPKFKNKRDVSNFDKLF 716 GCG G R I+EH FFR I+W+K+E +EIQPPYKPK ++KRD SNFDK F Sbjct: 585 GCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEF 634
>sp|P05771|KPCB_HUMAN Protein kinase C, beta type (PKC-beta) (PKC-B) Length = 671 Score = 389 bits (998), Expect = e-108 Identities = 182/230 (79%), Positives = 201/230 (87%) Frame = +3 Query: 27 QLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAVFYAAEIAVGLIFLHNHGIIY 206 QLHSCFQTMDRLYFVMEYVNGGDLMY IQQ G+FKEP AVFYAAEIA+GL FL + GIIY Sbjct: 405 QLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIY 464 Query: 207 RDLKLDNVLLDSEGHIKIADFGMCKENIIGNATTKTFCGTPDYIAPEIIKYQPYGKSVDW 386 RDLKLDNV+LDSEGHIKIADFGMCKENI TTKTFCGTPDYIAPEII YQPYGKSVDW Sbjct: 465 RDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDW 524 Query: 387 WAFGVLLYEMLAGQPPFDGEDEEDLFNSITNHNVSFPRSMSKEAVNVCRGLMTKDVNKRL 566 WAFGVLLYEMLAGQ PF+GEDE++LF SI HNV++P+SMSKEAV +C+GLMTK KRL Sbjct: 525 WAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRL 584 Query: 567 GCGVNGVRQIQEHVFFRRIEWDKIELREIQPPYKPKFKNKRDVSNFDKLF 716 GCG G R I+EH FFR I+W+K+E +EIQPPYKPK ++KRD SNFDK F Sbjct: 585 GCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEF 634
>sp|P05772|KPCB_RABIT Protein kinase C, beta type (PKC-beta) (PKC-B) Length = 671 Score = 387 bits (995), Expect = e-107 Identities = 181/230 (78%), Positives = 201/230 (87%) Frame = +3 Query: 27 QLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAVFYAAEIAVGLIFLHNHGIIY 206 QLHSCFQTMDRLYFVMEYVNGGDLMY IQQ G+FKEP AVFYAAEIA+GL FL + GIIY Sbjct: 405 QLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIY 464 Query: 207 RDLKLDNVLLDSEGHIKIADFGMCKENIIGNATTKTFCGTPDYIAPEIIKYQPYGKSVDW 386 RDLKLDNV+LDSEGHIKIADFGMCKENI TTKTFCGTPDYIAPEII YQPYGKSVDW Sbjct: 465 RDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDW 524 Query: 387 WAFGVLLYEMLAGQPPFDGEDEEDLFNSITNHNVSFPRSMSKEAVNVCRGLMTKDVNKRL 566 WAFGVLLYEMLAGQ PF+GEDE++LF SI HNV++P+SMSKEAV +C+GLMTK KRL Sbjct: 525 WAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRL 584 Query: 567 GCGVNGVRQIQEHVFFRRIEWDKIELREIQPPYKPKFKNKRDVSNFDKLF 716 GCG G R I++H FFR I+W+K+E +EIQPPYKPK ++KRD SNFDK F Sbjct: 585 GCGPEGERDIKDHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEF 634
>sp|P04409|KPCA_BOVIN Protein kinase C, alpha type (PKC-alpha) (PKC-A) Length = 672 Score = 382 bits (982), Expect = e-106 Identities = 177/230 (76%), Positives = 200/230 (86%) Frame = +3 Query: 27 QLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAVFYAAEIAVGLIFLHNHGIIY 206 QLHSCFQT+DRLYFVMEYVNGGDLMY IQQ GKFKEP AVFYAAEI++GL FLH GIIY Sbjct: 402 QLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIY 461 Query: 207 RDLKLDNVLLDSEGHIKIADFGMCKENIIGNATTKTFCGTPDYIAPEIIKYQPYGKSVDW 386 RDLKLDNV+LDSEGHIKIADFGMCKE+++ TT+TFCGTPDYIAPEII YQPYGKSVDW Sbjct: 462 RDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDW 521 Query: 387 WAFGVLLYEMLAGQPPFDGEDEEDLFNSITNHNVSFPRSMSKEAVNVCRGLMTKDVNKRL 566 WA+GVLLYEMLAGQPPFDGEDE++LF SI HNVS+P+S+SKEAV++C+GLMTK KRL Sbjct: 522 WAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPGKRL 581 Query: 567 GCGVNGVRQIQEHVFFRRIEWDKIELREIQPPYKPKFKNKRDVSNFDKLF 716 GCG G R ++EH FFRRI+W+K+E REIQPP+KPK K NFDK F Sbjct: 582 GCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCGK-GAENFDKFF 630
>sp|P05696|KPCA_RAT Protein kinase C, alpha type (PKC-alpha) (PKC-A) Length = 672 Score = 382 bits (980), Expect = e-106 Identities = 177/230 (76%), Positives = 200/230 (86%) Frame = +3 Query: 27 QLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAVFYAAEIAVGLIFLHNHGIIY 206 QLHSCFQT+DRLYFVMEYVNGGDLMY IQQ GKFKEP AVFYAAEI++GL FLH GIIY Sbjct: 402 QLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIY 461 Query: 207 RDLKLDNVLLDSEGHIKIADFGMCKENIIGNATTKTFCGTPDYIAPEIIKYQPYGKSVDW 386 RDLKLDNV+LDSEGHIKIADFGMCKE+++ TT+TFCGTPDYIAPEII YQPYGKSVDW Sbjct: 462 RDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDW 521 Query: 387 WAFGVLLYEMLAGQPPFDGEDEEDLFNSITNHNVSFPRSMSKEAVNVCRGLMTKDVNKRL 566 WA+GVLLYEMLAGQPPFDGEDE++LF SI HNVS+P+S+SKEAV++C+GLMTK KRL Sbjct: 522 WAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRL 581 Query: 567 GCGVNGVRQIQEHVFFRRIEWDKIELREIQPPYKPKFKNKRDVSNFDKLF 716 GCG G R ++EH FFRRI+W+K+E REIQPP+KPK K NFDK F Sbjct: 582 GCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCGK-GAENFDKFF 630
>sp|P17252|KPCA_HUMAN Protein kinase C, alpha type (PKC-alpha) (PKC-A) Length = 672 Score = 382 bits (980), Expect = e-106 Identities = 177/230 (76%), Positives = 200/230 (86%) Frame = +3 Query: 27 QLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAVFYAAEIAVGLIFLHNHGIIY 206 QLHSCFQT+DRLYFVMEYVNGGDLMY IQQ GKFKEP AVFYAAEI++GL FLH GIIY Sbjct: 402 QLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIY 461 Query: 207 RDLKLDNVLLDSEGHIKIADFGMCKENIIGNATTKTFCGTPDYIAPEIIKYQPYGKSVDW 386 RDLKLDNV+LDSEGHIKIADFGMCKE+++ TT+TFCGTPDYIAPEII YQPYGKSVDW Sbjct: 462 RDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDW 521 Query: 387 WAFGVLLYEMLAGQPPFDGEDEEDLFNSITNHNVSFPRSMSKEAVNVCRGLMTKDVNKRL 566 WA+GVLLYEMLAGQPPFDGEDE++LF SI HNVS+P+S+SKEAV++C+GLMTK KRL Sbjct: 522 WAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRL 581 Query: 567 GCGVNGVRQIQEHVFFRRIEWDKIELREIQPPYKPKFKNKRDVSNFDKLF 716 GCG G R ++EH FFRRI+W+K+E REIQPP+KPK K NFDK F Sbjct: 582 GCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCGK-GAENFDKFF 630
>sp|P10102|KPCA_RABIT Protein kinase C, alpha type (PKC-alpha) (PKC-A) Length = 672 Score = 382 bits (980), Expect = e-106 Identities = 177/230 (76%), Positives = 200/230 (86%) Frame = +3 Query: 27 QLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAVFYAAEIAVGLIFLHNHGIIY 206 QLHSCFQT+DRLYFVMEYVNGGDLMY IQQ GKFKEP AVFYAAEI++GL FLH GIIY Sbjct: 402 QLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIY 461 Query: 207 RDLKLDNVLLDSEGHIKIADFGMCKENIIGNATTKTFCGTPDYIAPEIIKYQPYGKSVDW 386 RDLKLDNV+LDSEGHIKIADFGMCKE+++ TT+TFCGTPDYIAPEII YQPYGKSVDW Sbjct: 462 RDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDW 521 Query: 387 WAFGVLLYEMLAGQPPFDGEDEEDLFNSITNHNVSFPRSMSKEAVNVCRGLMTKDVNKRL 566 WA+GVLLYEMLAGQPPFDGEDE++LF SI HNVS+P+S+SKEAV++C+GLMTK KRL Sbjct: 522 WAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRL 581 Query: 567 GCGVNGVRQIQEHVFFRRIEWDKIELREIQPPYKPKFKNKRDVSNFDKLF 716 GCG G R ++EH FFRRI+W+K+E REIQPP+KPK K NFDK F Sbjct: 582 GCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCGK-GAENFDKFF 630
>sp|P20444|KPCA_MOUSE Protein kinase C, alpha type (PKC-alpha) (PKC-A) Length = 672 Score = 378 bits (971), Expect = e-105 Identities = 175/230 (76%), Positives = 200/230 (86%) Frame = +3 Query: 27 QLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAVFYAAEIAVGLIFLHNHGIIY 206 QLHSCFQT+DRLYFVMEYVNGGDLMY IQQ GKFKEP AVFYAAEI++GL FLH GIIY Sbjct: 402 QLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIY 461 Query: 207 RDLKLDNVLLDSEGHIKIADFGMCKENIIGNATTKTFCGTPDYIAPEIIKYQPYGKSVDW 386 RDLKL+NV+L+SEGHIKIADFGMCKE+++ TT+TFCGTPDYIAPEII YQPYGKSVDW Sbjct: 462 RDLKLNNVMLNSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDW 521 Query: 387 WAFGVLLYEMLAGQPPFDGEDEEDLFNSITNHNVSFPRSMSKEAVNVCRGLMTKDVNKRL 566 WA+GVLLYEMLAGQPPFDGEDE++LF SI HNVS+P+S+SKEAV++C+GLMTK KRL Sbjct: 522 WAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKQPAKRL 581 Query: 567 GCGVNGVRQIQEHVFFRRIEWDKIELREIQPPYKPKFKNKRDVSNFDKLF 716 GCG G R ++EH FFRRI+W+K+E REIQPP+KPK K NFDK F Sbjct: 582 GCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCGK-GAENFDKFF 630
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 86,634,923 Number of Sequences: 369166 Number of extensions: 1785463 Number of successful extensions: 8794 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 6562 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6857 length of database: 68,354,980 effective HSP length: 107 effective length of database: 48,588,335 effective search space used: 6365071885 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)