Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_006_A13
(718 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q16974|KPC1_APLCA Calcium-dependent protein kinase C (AP... 402 e-112
sp|P05130|KPC1_DROME Protein kinase C, brain isozyme (PKC) ... 394 e-109
sp|P68403|KPCB_RAT Protein kinase C, beta type (PKC-beta) (... 389 e-108
sp|P05771|KPCB_HUMAN Protein kinase C, beta type (PKC-beta)... 389 e-108
sp|P05772|KPCB_RABIT Protein kinase C, beta type (PKC-beta)... 387 e-107
sp|P04409|KPCA_BOVIN Protein kinase C, alpha type (PKC-alph... 382 e-106
sp|P05696|KPCA_RAT Protein kinase C, alpha type (PKC-alpha)... 382 e-106
sp|P17252|KPCA_HUMAN Protein kinase C, alpha type (PKC-alph... 382 e-106
sp|P10102|KPCA_RABIT Protein kinase C, alpha type (PKC-alph... 382 e-106
sp|P20444|KPCA_MOUSE Protein kinase C, alpha type (PKC-alph... 378 e-105
>sp|Q16974|KPC1_APLCA Calcium-dependent protein kinase C (APL I)
Length = 649
Score = 402 bits (1032), Expect = e-112
Identities = 180/231 (77%), Positives = 213/231 (92%)
Frame = +3
Query: 24 VQLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAVFYAAEIAVGLIFLHNHGII 203
VQLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVA FYAAEIA+GL +LH GI+
Sbjct: 382 VQLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAAFYAAEIAIGLFYLHTQGIV 441
Query: 204 YRDLKLDNVLLDSEGHIKIADFGMCKENIIGNATTKTFCGTPDYIAPEIIKYQPYGKSVD 383
YRDLKLDNV+LD+EGHIKIADFGMCKENI+G+ TT+TFCGTPDYIAPEI+ YQPYG+SVD
Sbjct: 442 YRDLKLDNVMLDAEGHIKIADFGMCKENIMGDKTTRTFCGTPDYIAPEIVLYQPYGRSVD 501
Query: 384 WWAFGVLLYEMLAGQPPFDGEDEEDLFNSITNHNVSFPRSMSKEAVNVCRGLMTKDVNKR 563
WWA+GVLLYEMLAGQPPFDGEDEE+LF SIT+HNVS+P+++S+EAV++C+GL+TK KR
Sbjct: 502 WWAYGVLLYEMLAGQPPFDGEDEEELFTSITDHNVSYPKALSREAVSLCKGLLTKTPAKR 561
Query: 564 LGCGVNGVRQIQEHVFFRRIEWDKIELREIQPPYKPKFKNKRDVSNFDKLF 716
LGCG NG R I++ FFR I+W++IELRE+QPPYKP+ K+++DVSNFD+ F
Sbjct: 562 LGCGPNGERDIKDRAFFRPIQWERIELREVQPPYKPRIKSRKDVSNFDREF 612
>sp|P05130|KPC1_DROME Protein kinase C, brain isozyme (PKC) (dPKC53E(BR))
Length = 679
Score = 394 bits (1011), Expect = e-109
Identities = 179/231 (77%), Positives = 207/231 (89%)
Frame = +3
Query: 24 VQLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAVFYAAEIAVGLIFLHNHGII 203
VQLHSCFQTMDRL+FVMEYVNGGDLM++IQQ GKFKEPVAVFYAAEIA GL FLH GI+
Sbjct: 412 VQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHTKGIL 471
Query: 204 YRDLKLDNVLLDSEGHIKIADFGMCKENIIGNATTKTFCGTPDYIAPEIIKYQPYGKSVD 383
YRDLKLDNVLLD++GH+KIADFGMCKENI+G+ TTKTFCGTPDYIAPEII YQPYGKSVD
Sbjct: 472 YRDLKLDNVLLDADGHVKIADFGMCKENIVGDKTTKTFCGTPDYIAPEIILYQPYGKSVD 531
Query: 384 WWAFGVLLYEMLAGQPPFDGEDEEDLFNSITNHNVSFPRSMSKEAVNVCRGLMTKDVNKR 563
WWA+GVLLYEML GQPPFDGEDEE+LF +IT+HNVS+P+S+SKEA C+G +TK NKR
Sbjct: 532 WWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAKEACKGFLTKQPNKR 591
Query: 564 LGCGVNGVRQIQEHVFFRRIEWDKIELREIQPPYKPKFKNKRDVSNFDKLF 716
LGCG +G ++ H FFRRI+W+KIE RE+QPP+KPK K+++DVSNFDK F
Sbjct: 592 LGCGSSGEEDVRLHPFFRRIDWEKIENREVQPPFKPKIKHRKDVSNFDKQF 642
>sp|P68403|KPCB_RAT Protein kinase C, beta type (PKC-beta) (PKC-B)
Length = 671
Score = 389 bits (998), Expect = e-108
Identities = 182/230 (79%), Positives = 201/230 (87%)
Frame = +3
Query: 27 QLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAVFYAAEIAVGLIFLHNHGIIY 206
QLHSCFQTMDRLYFVMEYVNGGDLMY IQQ G+FKEP AVFYAAEIA+GL FL + GIIY
Sbjct: 405 QLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIY 464
Query: 207 RDLKLDNVLLDSEGHIKIADFGMCKENIIGNATTKTFCGTPDYIAPEIIKYQPYGKSVDW 386
RDLKLDNV+LDSEGHIKIADFGMCKENI TTKTFCGTPDYIAPEII YQPYGKSVDW
Sbjct: 465 RDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDW 524
Query: 387 WAFGVLLYEMLAGQPPFDGEDEEDLFNSITNHNVSFPRSMSKEAVNVCRGLMTKDVNKRL 566
WAFGVLLYEMLAGQ PF+GEDE++LF SI HNV++P+SMSKEAV +C+GLMTK KRL
Sbjct: 525 WAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRL 584
Query: 567 GCGVNGVRQIQEHVFFRRIEWDKIELREIQPPYKPKFKNKRDVSNFDKLF 716
GCG G R I+EH FFR I+W+K+E +EIQPPYKPK ++KRD SNFDK F
Sbjct: 585 GCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEF 634
>sp|P05771|KPCB_HUMAN Protein kinase C, beta type (PKC-beta) (PKC-B)
Length = 671
Score = 389 bits (998), Expect = e-108
Identities = 182/230 (79%), Positives = 201/230 (87%)
Frame = +3
Query: 27 QLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAVFYAAEIAVGLIFLHNHGIIY 206
QLHSCFQTMDRLYFVMEYVNGGDLMY IQQ G+FKEP AVFYAAEIA+GL FL + GIIY
Sbjct: 405 QLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIY 464
Query: 207 RDLKLDNVLLDSEGHIKIADFGMCKENIIGNATTKTFCGTPDYIAPEIIKYQPYGKSVDW 386
RDLKLDNV+LDSEGHIKIADFGMCKENI TTKTFCGTPDYIAPEII YQPYGKSVDW
Sbjct: 465 RDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDW 524
Query: 387 WAFGVLLYEMLAGQPPFDGEDEEDLFNSITNHNVSFPRSMSKEAVNVCRGLMTKDVNKRL 566
WAFGVLLYEMLAGQ PF+GEDE++LF SI HNV++P+SMSKEAV +C+GLMTK KRL
Sbjct: 525 WAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRL 584
Query: 567 GCGVNGVRQIQEHVFFRRIEWDKIELREIQPPYKPKFKNKRDVSNFDKLF 716
GCG G R I+EH FFR I+W+K+E +EIQPPYKPK ++KRD SNFDK F
Sbjct: 585 GCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEF 634
>sp|P05772|KPCB_RABIT Protein kinase C, beta type (PKC-beta) (PKC-B)
Length = 671
Score = 387 bits (995), Expect = e-107
Identities = 181/230 (78%), Positives = 201/230 (87%)
Frame = +3
Query: 27 QLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAVFYAAEIAVGLIFLHNHGIIY 206
QLHSCFQTMDRLYFVMEYVNGGDLMY IQQ G+FKEP AVFYAAEIA+GL FL + GIIY
Sbjct: 405 QLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIY 464
Query: 207 RDLKLDNVLLDSEGHIKIADFGMCKENIIGNATTKTFCGTPDYIAPEIIKYQPYGKSVDW 386
RDLKLDNV+LDSEGHIKIADFGMCKENI TTKTFCGTPDYIAPEII YQPYGKSVDW
Sbjct: 465 RDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDW 524
Query: 387 WAFGVLLYEMLAGQPPFDGEDEEDLFNSITNHNVSFPRSMSKEAVNVCRGLMTKDVNKRL 566
WAFGVLLYEMLAGQ PF+GEDE++LF SI HNV++P+SMSKEAV +C+GLMTK KRL
Sbjct: 525 WAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRL 584
Query: 567 GCGVNGVRQIQEHVFFRRIEWDKIELREIQPPYKPKFKNKRDVSNFDKLF 716
GCG G R I++H FFR I+W+K+E +EIQPPYKPK ++KRD SNFDK F
Sbjct: 585 GCGPEGERDIKDHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEF 634
>sp|P04409|KPCA_BOVIN Protein kinase C, alpha type (PKC-alpha) (PKC-A)
Length = 672
Score = 382 bits (982), Expect = e-106
Identities = 177/230 (76%), Positives = 200/230 (86%)
Frame = +3
Query: 27 QLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAVFYAAEIAVGLIFLHNHGIIY 206
QLHSCFQT+DRLYFVMEYVNGGDLMY IQQ GKFKEP AVFYAAEI++GL FLH GIIY
Sbjct: 402 QLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIY 461
Query: 207 RDLKLDNVLLDSEGHIKIADFGMCKENIIGNATTKTFCGTPDYIAPEIIKYQPYGKSVDW 386
RDLKLDNV+LDSEGHIKIADFGMCKE+++ TT+TFCGTPDYIAPEII YQPYGKSVDW
Sbjct: 462 RDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDW 521
Query: 387 WAFGVLLYEMLAGQPPFDGEDEEDLFNSITNHNVSFPRSMSKEAVNVCRGLMTKDVNKRL 566
WA+GVLLYEMLAGQPPFDGEDE++LF SI HNVS+P+S+SKEAV++C+GLMTK KRL
Sbjct: 522 WAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPGKRL 581
Query: 567 GCGVNGVRQIQEHVFFRRIEWDKIELREIQPPYKPKFKNKRDVSNFDKLF 716
GCG G R ++EH FFRRI+W+K+E REIQPP+KPK K NFDK F
Sbjct: 582 GCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCGK-GAENFDKFF 630
>sp|P05696|KPCA_RAT Protein kinase C, alpha type (PKC-alpha) (PKC-A)
Length = 672
Score = 382 bits (980), Expect = e-106
Identities = 177/230 (76%), Positives = 200/230 (86%)
Frame = +3
Query: 27 QLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAVFYAAEIAVGLIFLHNHGIIY 206
QLHSCFQT+DRLYFVMEYVNGGDLMY IQQ GKFKEP AVFYAAEI++GL FLH GIIY
Sbjct: 402 QLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIY 461
Query: 207 RDLKLDNVLLDSEGHIKIADFGMCKENIIGNATTKTFCGTPDYIAPEIIKYQPYGKSVDW 386
RDLKLDNV+LDSEGHIKIADFGMCKE+++ TT+TFCGTPDYIAPEII YQPYGKSVDW
Sbjct: 462 RDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDW 521
Query: 387 WAFGVLLYEMLAGQPPFDGEDEEDLFNSITNHNVSFPRSMSKEAVNVCRGLMTKDVNKRL 566
WA+GVLLYEMLAGQPPFDGEDE++LF SI HNVS+P+S+SKEAV++C+GLMTK KRL
Sbjct: 522 WAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRL 581
Query: 567 GCGVNGVRQIQEHVFFRRIEWDKIELREIQPPYKPKFKNKRDVSNFDKLF 716
GCG G R ++EH FFRRI+W+K+E REIQPP+KPK K NFDK F
Sbjct: 582 GCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCGK-GAENFDKFF 630
>sp|P17252|KPCA_HUMAN Protein kinase C, alpha type (PKC-alpha) (PKC-A)
Length = 672
Score = 382 bits (980), Expect = e-106
Identities = 177/230 (76%), Positives = 200/230 (86%)
Frame = +3
Query: 27 QLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAVFYAAEIAVGLIFLHNHGIIY 206
QLHSCFQT+DRLYFVMEYVNGGDLMY IQQ GKFKEP AVFYAAEI++GL FLH GIIY
Sbjct: 402 QLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIY 461
Query: 207 RDLKLDNVLLDSEGHIKIADFGMCKENIIGNATTKTFCGTPDYIAPEIIKYQPYGKSVDW 386
RDLKLDNV+LDSEGHIKIADFGMCKE+++ TT+TFCGTPDYIAPEII YQPYGKSVDW
Sbjct: 462 RDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDW 521
Query: 387 WAFGVLLYEMLAGQPPFDGEDEEDLFNSITNHNVSFPRSMSKEAVNVCRGLMTKDVNKRL 566
WA+GVLLYEMLAGQPPFDGEDE++LF SI HNVS+P+S+SKEAV++C+GLMTK KRL
Sbjct: 522 WAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRL 581
Query: 567 GCGVNGVRQIQEHVFFRRIEWDKIELREIQPPYKPKFKNKRDVSNFDKLF 716
GCG G R ++EH FFRRI+W+K+E REIQPP+KPK K NFDK F
Sbjct: 582 GCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCGK-GAENFDKFF 630
>sp|P10102|KPCA_RABIT Protein kinase C, alpha type (PKC-alpha) (PKC-A)
Length = 672
Score = 382 bits (980), Expect = e-106
Identities = 177/230 (76%), Positives = 200/230 (86%)
Frame = +3
Query: 27 QLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAVFYAAEIAVGLIFLHNHGIIY 206
QLHSCFQT+DRLYFVMEYVNGGDLMY IQQ GKFKEP AVFYAAEI++GL FLH GIIY
Sbjct: 402 QLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIY 461
Query: 207 RDLKLDNVLLDSEGHIKIADFGMCKENIIGNATTKTFCGTPDYIAPEIIKYQPYGKSVDW 386
RDLKLDNV+LDSEGHIKIADFGMCKE+++ TT+TFCGTPDYIAPEII YQPYGKSVDW
Sbjct: 462 RDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDW 521
Query: 387 WAFGVLLYEMLAGQPPFDGEDEEDLFNSITNHNVSFPRSMSKEAVNVCRGLMTKDVNKRL 566
WA+GVLLYEMLAGQPPFDGEDE++LF SI HNVS+P+S+SKEAV++C+GLMTK KRL
Sbjct: 522 WAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRL 581
Query: 567 GCGVNGVRQIQEHVFFRRIEWDKIELREIQPPYKPKFKNKRDVSNFDKLF 716
GCG G R ++EH FFRRI+W+K+E REIQPP+KPK K NFDK F
Sbjct: 582 GCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCGK-GAENFDKFF 630
>sp|P20444|KPCA_MOUSE Protein kinase C, alpha type (PKC-alpha) (PKC-A)
Length = 672
Score = 378 bits (971), Expect = e-105
Identities = 175/230 (76%), Positives = 200/230 (86%)
Frame = +3
Query: 27 QLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAVFYAAEIAVGLIFLHNHGIIY 206
QLHSCFQT+DRLYFVMEYVNGGDLMY IQQ GKFKEP AVFYAAEI++GL FLH GIIY
Sbjct: 402 QLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIY 461
Query: 207 RDLKLDNVLLDSEGHIKIADFGMCKENIIGNATTKTFCGTPDYIAPEIIKYQPYGKSVDW 386
RDLKL+NV+L+SEGHIKIADFGMCKE+++ TT+TFCGTPDYIAPEII YQPYGKSVDW
Sbjct: 462 RDLKLNNVMLNSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDW 521
Query: 387 WAFGVLLYEMLAGQPPFDGEDEEDLFNSITNHNVSFPRSMSKEAVNVCRGLMTKDVNKRL 566
WA+GVLLYEMLAGQPPFDGEDE++LF SI HNVS+P+S+SKEAV++C+GLMTK KRL
Sbjct: 522 WAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKQPAKRL 581
Query: 567 GCGVNGVRQIQEHVFFRRIEWDKIELREIQPPYKPKFKNKRDVSNFDKLF 716
GCG G R ++EH FFRRI+W+K+E REIQPP+KPK K NFDK F
Sbjct: 582 GCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCGK-GAENFDKFF 630
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,634,923
Number of Sequences: 369166
Number of extensions: 1785463
Number of successful extensions: 8794
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6562
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6857
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6365071885
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)