Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_O24
(254 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P35034|TRYP_PLEPL Trypsin precursor 59 3e-09
sp|Q9UKR3|KLK13_HUMAN Kallikrein 13 precursor (Kallikrein-l... 55 5e-08
sp|P32822|TRYB_RAT Trypsin V-B precursor 55 6e-08
sp|P32821|TRYA_RAT Trypsin V-A precursor 55 6e-08
sp|Q29463|TRY2_BOVIN Anionic trypsin precursor 52 4e-07
sp|P70375|FA7_MOUSE Coagulation factor VII precursor (Serum... 50 1e-06
sp|P51779|CFAD_PIG Complement factor D precursor (C3 conver... 50 2e-06
sp|P07146|TRY2_MOUSE Anionic trypsin II precursor (Pretryps... 49 3e-06
sp|P00760|TRY1_BOVIN Cationic trypsin precursor (Beta-tryps... 49 4e-06
sp|P08246|ELNE_HUMAN Leukocyte elastase precursor (Neutroph... 49 5e-06
>sp|P35034|TRYP_PLEPL Trypsin precursor
Length = 250
Score = 58.9 bits (141), Expect = 3e-09
Identities = 30/80 (37%), Positives = 45/80 (56%)
Frame = +1
Query: 1 PQMVSIKVQGNHFCGGILLNGNTVLTAAHCVWDMRNWNVNTFKYYQMKVYMGEYDLYRMN 180
P M S+ G HFCGG+L+N VL+ AHC W + Y M+V +GE+DL +
Sbjct: 35 PFMASLNY-GYHFCGGVLINNQWVLSVAHC-W---------YNPYAMQVMLGEHDLRKFE 83
Query: 181 GVEKIFQVTKTIIHPSYRHE 240
G E++ + I HP+Y ++
Sbjct: 84 GTEQLMKTDTIIWHPNYDYQ 103
>sp|Q9UKR3|KLK13_HUMAN Kallikrein 13 precursor (Kallikrein-like protein 4) (KLK-L4)
Length = 277
Score = 55.1 bits (131), Expect = 5e-08
Identities = 29/84 (34%), Positives = 46/84 (54%)
Frame = +1
Query: 1 PQMVSIKVQGNHFCGGILLNGNTVLTAAHCVWDMRNWNVNTFKYYQMKVYMGEYDLYRMN 180
P ++ VQG CGG+L++ VLTAAHC+ + +KVY+G++ L R+
Sbjct: 48 PWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKE------------GLKVYLGKHALGRVE 95
Query: 181 GVEKIFQVTKTIIHPSYRHEYAYL 252
E++ +V +I HP YR +L
Sbjct: 96 AGEQVREVVHSIPHPEYRRSPTHL 119
>sp|P32822|TRYB_RAT Trypsin V-B precursor
Length = 246
Score = 54.7 bits (130), Expect = 6e-08
Identities = 27/77 (35%), Positives = 41/77 (53%)
Frame = +1
Query: 1 PQMVSIKVQGNHFCGGILLNGNTVLTAAHCVWDMRNWNVNTFKYYQMKVYMGEYDLYRMN 180
P VS+ G+H CGG L+ VL+AAHC + Q++V +GE+++Y +
Sbjct: 37 PYQVSLNA-GSHICGGSLITDQWVLSAAHCY------------HPQLQVRLGEHNIYEIE 83
Query: 181 GVEKIFQVTKTIIHPSY 231
G E+ K I+HP Y
Sbjct: 84 GAEQFIDAAKMILHPDY 100
>sp|P32821|TRYA_RAT Trypsin V-A precursor
Length = 246
Score = 54.7 bits (130), Expect = 6e-08
Identities = 27/77 (35%), Positives = 41/77 (53%)
Frame = +1
Query: 1 PQMVSIKVQGNHFCGGILLNGNTVLTAAHCVWDMRNWNVNTFKYYQMKVYMGEYDLYRMN 180
P VS+ G+H CGG L+ VL+AAHC + Q++V +GE+++Y +
Sbjct: 37 PYQVSLNA-GSHICGGSLITDQWVLSAAHCY------------HPQLQVRLGEHNIYEIE 83
Query: 181 GVEKIFQVTKTIIHPSY 231
G E+ K I+HP Y
Sbjct: 84 GAEQFIDAAKMILHPDY 100
>sp|Q29463|TRY2_BOVIN Anionic trypsin precursor
Length = 247
Score = 52.0 bits (123), Expect = 4e-07
Identities = 28/77 (36%), Positives = 40/77 (51%)
Frame = +1
Query: 1 PQMVSIKVQGNHFCGGILLNGNTVLTAAHCVWDMRNWNVNTFKYYQMKVYMGEYDLYRMN 180
P VS+ G HFCGG L+N V++AAHC Y ++V +GEY++ +
Sbjct: 36 PYQVSLNA-GYHFCGGSLINDQWVVSAAHCY------------QYHIQVRLGEYNIDVLE 82
Query: 181 GVEKIFQVTKTIIHPSY 231
G E+ +K I HP Y
Sbjct: 83 GGEQFIDASKIIRHPKY 99
>sp|P70375|FA7_MOUSE Coagulation factor VII precursor (Serum prothrombin conversion
accelerator) [Contains: Factor VII light chain; Factor
VII heavy chain]
Length = 446
Score = 50.4 bits (119), Expect = 1e-06
Identities = 25/77 (32%), Positives = 41/77 (53%)
Frame = +1
Query: 1 PQMVSIKVQGNHFCGGILLNGNTVLTAAHCVWDMRNWNVNTFKYYQMKVYMGEYDLYRMN 180
P +K+ G CG +LL+ ++TAAHC ++R W + V MGE+D +
Sbjct: 206 PWQAVLKINGLLLCGAVLLDARWIVTAAHCFDNIRYWG-------NITVVMGEHDFSEKD 258
Query: 181 GVEKIFQVTKTIIHPSY 231
G E++ +VT+ I+ Y
Sbjct: 259 GDEQVRRVTQVIMPDKY 275
>sp|P51779|CFAD_PIG Complement factor D precursor (C3 convertase activator) (Properdin
factor D) (Adipsin)
Length = 259
Score = 49.7 bits (117), Expect = 2e-06
Identities = 23/75 (30%), Positives = 42/75 (56%)
Frame = +1
Query: 1 PQMVSIKVQGNHFCGGILLNGNTVLTAAHCVWDMRNWNVNTFKYYQMKVYMGEYDLYRMN 180
P M S++V G H CGG L++ VL+AAHC+ D+ +++V +G + L +
Sbjct: 39 PYMASVQVNGKHVCGGFLVSEQWVLSAAHCLEDVAEG--------KLQVLLGAHSLSQPE 90
Query: 181 GVEKIFQVTKTIIHP 225
++++ V + + HP
Sbjct: 91 PSKRLYDVLRAVPHP 105
>sp|P07146|TRY2_MOUSE Anionic trypsin II precursor (Pretrypsinogen II)
Length = 246
Score = 49.3 bits (116), Expect = 3e-06
Identities = 27/77 (35%), Positives = 41/77 (53%)
Frame = +1
Query: 1 PQMVSIKVQGNHFCGGILLNGNTVLTAAHCVWDMRNWNVNTFKYYQMKVYMGEYDLYRMN 180
P VS+ G HFCGG L+N V++AAHC Y+++V +GE+++ +
Sbjct: 36 PYQVSLNA-GYHFCGGSLINDQWVVSAAHCY------------KYRIQVRLGEHNINVLE 82
Query: 181 GVEKIFQVTKTIIHPSY 231
G E+ K I HP+Y
Sbjct: 83 GNEQFVDSAKIIRHPNY 99
>sp|P00760|TRY1_BOVIN Cationic trypsin precursor (Beta-trypsin) [Contains: Alpha-trypsin
chain 1; Alpha-trypsin chain 2]
Length = 243
Score = 48.9 bits (115), Expect = 4e-06
Identities = 27/77 (35%), Positives = 41/77 (53%)
Frame = +1
Query: 1 PQMVSIKVQGNHFCGGILLNGNTVLTAAHCVWDMRNWNVNTFKYYQMKVYMGEYDLYRMN 180
P VS+ G HFCGG L+N V++AAHC ++V +GE ++ +
Sbjct: 33 PYQVSLN-SGYHFCGGSLINSQWVVSAAHCYKS------------GIQVRLGEDNINVVE 79
Query: 181 GVEKIFQVTKTIIHPSY 231
G E+ +K+I+HPSY
Sbjct: 80 GNEQFISASKSIVHPSY 96
>sp|P08246|ELNE_HUMAN Leukocyte elastase precursor (Neutrophil elastase) (PMN elastase)
(Bone marrow serine protease) (Medullasin)
Length = 267
Score = 48.5 bits (114), Expect = 5e-06
Identities = 26/70 (37%), Positives = 41/70 (58%)
Frame = +1
Query: 1 PQMVSIKVQGNHFCGGILLNGNTVLTAAHCVWDMRNWNVNTFKYYQMKVYMGEYDLYRMN 180
P MVS++++G HFCG L+ N V++AAHCV N NV ++V +G ++L R
Sbjct: 42 PFMVSLQLRGGHFCGATLIAPNFVMSAAHCV---ANVNVRA-----VRVVLGAHNLSRRE 93
Query: 181 GVEKIFQVTK 210
++F V +
Sbjct: 94 PTRQVFAVQR 103
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,650,398
Number of Sequences: 369166
Number of extensions: 577857
Number of successful extensions: 1878
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1773
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1797
length of database: 68,354,980
effective HSP length: 55
effective length of database: 58,194,555
effective search space used: 1687642095
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)