Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_M16
(767 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P22700|ATC1_DROME Calcium-transporting ATPase sarcoplasm... 342 9e-94
sp|P11507|AT2A2_RAT Sarcoplasmic/endoplasmic reticulum calc... 333 2e-91
sp|O55143|AT2A2_MOUSE Sarcoplasmic/endoplasmic reticulum ca... 333 2e-91
sp|Q03669|AT2A2_CHICK Sarcoplasmic/endoplasmic reticulum ca... 333 2e-91
sp|P20647|AT2A2_RABIT Sarcoplasmic/endoplasmic reticulum ca... 333 3e-91
sp|P16615|AT2A2_HUMAN Sarcoplasmic/endoplasmic reticulum ca... 333 3e-91
sp|O46674|AT2A2_CANFA Sarcoplasmic/endoplasmic reticulum ca... 333 3e-91
sp|Q00779|AT2A2_FELCA Sarcoplasmic/endoplasmic reticulum ca... 333 3e-91
sp|P11607|AT2A2_PIG Sarcoplasmic/endoplasmic reticulum calc... 333 4e-91
sp|Q92105|AT2A1_RANES Sarcoplasmic/endoplasmic reticulum ca... 331 2e-90
>sp|P22700|ATC1_DROME Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type
(Calcium pump)
Length = 1020
Score = 342 bits (876), Expect = 9e-94
Identities = 167/239 (69%), Positives = 195/239 (81%)
Frame = +2
Query: 2 VCIFLTAALGMPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMERPPRSPKESLISGW 181
V IFLTAALG+PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIME+PPR E LISGW
Sbjct: 773 VSIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKPPRKADEGLISGW 832
Query: 182 LFFRYMAIGCYVGAATVGSAAWWFMRSPDGPSVSYYQLTHHLQCALEPNDFIGVDCKVFL 361
LFFRYMAIG YVGAATVG+AAWWF+ S +GP +SY+QLTHHL C ++F GVDCK+F
Sbjct: 833 LFFRYMAIGFYVGAATVGAAAWWFVFSDEGPKLSYWQLTHHLSCLGGGDEFKGVDCKIFS 892
Query: 362 NSKPMTMALSVLVLIEMLNALNSLSENQSIIKMPPWTNIWLILAITLSMSLHFLILEVGF 541
+ MTMALSVLV IEMLNA+NSLSENQS+I MPPW N+WLI ++ LS +LHF+IL V
Sbjct: 893 DPHAMTMALSVLVTIEMLNAMNSLSENQSLITMPPWCNLWLIGSMALSFTLHFVILYVDV 952
Query: 542 LAKVFQISPLSFSEWLTVMKFSFPVLLLDESLKVISRNQQNHKSIFNNCHMIVLMWAAF 718
L+ VFQ++PLS EW+TVMKFS PV+LLDE+LK ++R + +S H IVLMWA F
Sbjct: 953 LSTVFQVTPLSAEEWITVMKFSIPVVLLDETLKFVARKIADGESPIYKMHGIVLMWAVF 1011
>sp|P11507|AT2A2_RAT Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (Calcium pump 2)
(SERCA2) (SR Ca(2+)-ATPase 2) (Calcium-transporting
ATPase sarcoplasmic reticulum type, slow twitch skeletal
muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+)
ATPase)
Length = 1043
Score = 333 bits (855), Expect = 2e-91
Identities = 159/218 (72%), Positives = 186/218 (85%)
Frame = +2
Query: 2 VCIFLTAALGMPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMERPPRSPKESLISGW 181
VCIFLTAALG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM +PPR+PKE LISGW
Sbjct: 772 VCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGW 831
Query: 182 LFFRYMAIGCYVGAATVGSAAWWFMRSPDGPSVSYYQLTHHLQCALEPNDFIGVDCKVFL 361
LFFRY+AIGCYVGAATVG+AAWWF+ + GP VS+YQL+H LQC + DF GVDC +F
Sbjct: 832 LFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFE 891
Query: 362 NSKPMTMALSVLVLIEMLNALNSLSENQSIIKMPPWTNIWLILAITLSMSLHFLILEVGF 541
+ PMTMALSVLV IEM NALNSLSENQS+++MPPW NIWL+ +I LSMSLHFLIL V
Sbjct: 892 SPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEP 951
Query: 542 LAKVFQISPLSFSEWLTVMKFSFPVLLLDESLKVISRN 655
L +FQI+PL+ ++WL V+K S PV+L+DE+LK ++RN
Sbjct: 952 LPLIFQITPLNLTQWLMVLKISLPVILMDETLKFVARN 989
>sp|O55143|AT2A2_MOUSE Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (Calcium pump 2)
(SERCA2) (SR Ca(2+)-ATPase 2) (Calcium-transporting
ATPase sarcoplasmic reticulum type, slow twitch skeletal
muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+)
ATPase)
Length = 1044
Score = 333 bits (855), Expect = 2e-91
Identities = 159/218 (72%), Positives = 186/218 (85%)
Frame = +2
Query: 2 VCIFLTAALGMPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMERPPRSPKESLISGW 181
VCIFLTAALG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM +PPR+PKE LISGW
Sbjct: 772 VCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGW 831
Query: 182 LFFRYMAIGCYVGAATVGSAAWWFMRSPDGPSVSYYQLTHHLQCALEPNDFIGVDCKVFL 361
LFFRY+AIGCYVGAATVG+AAWWF+ + GP VS+YQL+H LQC + DF GVDC +F
Sbjct: 832 LFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFDGVDCAIFE 891
Query: 362 NSKPMTMALSVLVLIEMLNALNSLSENQSIIKMPPWTNIWLILAITLSMSLHFLILEVGF 541
+ PMTMALSVLV IEM NALNSLSENQS+++MPPW NIWL+ +I LSMSLHFLIL V
Sbjct: 892 SPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEP 951
Query: 542 LAKVFQISPLSFSEWLTVMKFSFPVLLLDESLKVISRN 655
L +FQI+PL+ ++WL V+K S PV+L+DE+LK ++RN
Sbjct: 952 LPLIFQITPLNLTQWLMVLKISLPVILMDETLKFVARN 989
>sp|Q03669|AT2A2_CHICK Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (Calcium pump 2)
(SERCA2) (SR Ca(2+)-ATPase 2) (Calcium-transporting
ATPase sarcoplasmic reticulum type, slow twitch skeletal
muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+)
ATPase)
Length = 1041
Score = 333 bits (855), Expect = 2e-91
Identities = 161/218 (73%), Positives = 186/218 (85%)
Frame = +2
Query: 2 VCIFLTAALGMPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMERPPRSPKESLISGW 181
VCIFLTAALG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM +PPR+PKE LISGW
Sbjct: 772 VCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGW 831
Query: 182 LFFRYMAIGCYVGAATVGSAAWWFMRSPDGPSVSYYQLTHHLQCALEPNDFIGVDCKVFL 361
LFFRY+AIGCYVGAATVG+AAWWF+ + GP V++YQL+H LQC + DF GVDC VF
Sbjct: 832 LFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVTFYQLSHFLQCKEDNPDFSGVDCVVFE 891
Query: 362 NSKPMTMALSVLVLIEMLNALNSLSENQSIIKMPPWTNIWLILAITLSMSLHFLILEVGF 541
+ PMTMALSVLV IEM NALNSLSENQS+++MPPW NIWL+ AI LSMSLHFLIL V
Sbjct: 892 SPYPMTMALSVLVTIEMCNALNSLSENQSLMRMPPWENIWLVGAICLSMSLHFLILYVEP 951
Query: 542 LAKVFQISPLSFSEWLTVMKFSFPVLLLDESLKVISRN 655
L +FQI+PL+ ++WL V+K S PV+LLDE+LK ++RN
Sbjct: 952 LPIIFQITPLNVTQWLMVLKISLPVILLDETLKYVARN 989
>sp|P20647|AT2A2_RABIT Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (Calcium pump 2)
(SERCA2) (SR Ca(2+)-ATPase 2) (Calcium-transporting
ATPase sarcoplasmic reticulum type, slow twitch skeletal
muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+)
ATPase)
Length = 1042
Score = 333 bits (854), Expect = 3e-91
Identities = 159/218 (72%), Positives = 186/218 (85%)
Frame = +2
Query: 2 VCIFLTAALGMPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMERPPRSPKESLISGW 181
VCIFLTAALG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM +PPR+PKE LISGW
Sbjct: 772 VCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGW 831
Query: 182 LFFRYMAIGCYVGAATVGSAAWWFMRSPDGPSVSYYQLTHHLQCALEPNDFIGVDCKVFL 361
LFFRY+AIGCYVGAATVG+AAWWF+ + GP VS+YQL+H LQC + DF GVDC +F
Sbjct: 832 LFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFE 891
Query: 362 NSKPMTMALSVLVLIEMLNALNSLSENQSIIKMPPWTNIWLILAITLSMSLHFLILEVGF 541
+ PMTMALSVLV IEM NALNSLSENQS+++MPPW NIWL+ +I LSMSLHFLIL V
Sbjct: 892 SPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEP 951
Query: 542 LAKVFQISPLSFSEWLTVMKFSFPVLLLDESLKVISRN 655
L +FQI+PL+ ++WL V+K S PV+L+DE+LK ++RN
Sbjct: 952 LPLIFQITPLNVTQWLMVLKISLPVILMDETLKFVARN 989
>sp|P16615|AT2A2_HUMAN Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (Calcium pump 2)
(SERCA2) (SR Ca(2+)-ATPase 2) (Calcium-transporting
ATPase sarcoplasmic reticulum type, slow twitch skeletal
muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+)
ATPase)
Length = 1042
Score = 333 bits (854), Expect = 3e-91
Identities = 159/218 (72%), Positives = 186/218 (85%)
Frame = +2
Query: 2 VCIFLTAALGMPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMERPPRSPKESLISGW 181
VCIFLTAALG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM +PPR+PKE LISGW
Sbjct: 772 VCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGW 831
Query: 182 LFFRYMAIGCYVGAATVGSAAWWFMRSPDGPSVSYYQLTHHLQCALEPNDFIGVDCKVFL 361
LFFRY+AIGCYVGAATVG+AAWWF+ + GP VS+YQL+H LQC + DF GVDC +F
Sbjct: 832 LFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFE 891
Query: 362 NSKPMTMALSVLVLIEMLNALNSLSENQSIIKMPPWTNIWLILAITLSMSLHFLILEVGF 541
+ PMTMALSVLV IEM NALNSLSENQS+++MPPW NIWL+ +I LSMSLHFLIL V
Sbjct: 892 SPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEP 951
Query: 542 LAKVFQISPLSFSEWLTVMKFSFPVLLLDESLKVISRN 655
L +FQI+PL+ ++WL V+K S PV+L+DE+LK ++RN
Sbjct: 952 LPLIFQITPLNVTQWLMVLKISLPVILMDETLKFVARN 989
>sp|O46674|AT2A2_CANFA Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (Calcium pump 2)
(SERCA2) (SR Ca(2+)-ATPase 2) (Calcium-transporting
ATPase sarcoplasmic reticulum type, slow twitch skeletal
muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+)
ATPase)
Length = 997
Score = 333 bits (854), Expect = 3e-91
Identities = 159/218 (72%), Positives = 186/218 (85%)
Frame = +2
Query: 2 VCIFLTAALGMPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMERPPRSPKESLISGW 181
VCIFLTAALG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM +PPR+PKE LISGW
Sbjct: 772 VCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGW 831
Query: 182 LFFRYMAIGCYVGAATVGSAAWWFMRSPDGPSVSYYQLTHHLQCALEPNDFIGVDCKVFL 361
LFFRY+AIGCYVGAATVG+AAWWF+ + GP VS+YQL+H LQC + DF GVDC +F
Sbjct: 832 LFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKDDNPDFEGVDCAIFE 891
Query: 362 NSKPMTMALSVLVLIEMLNALNSLSENQSIIKMPPWTNIWLILAITLSMSLHFLILEVGF 541
+ PMTMALSVLV IEM NALNSLSENQS+++MPPW NIWL+ +I LSMSLHFLIL V
Sbjct: 892 SPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEP 951
Query: 542 LAKVFQISPLSFSEWLTVMKFSFPVLLLDESLKVISRN 655
L +FQI+PL+ ++WL V+K S PV+L+DE+LK ++RN
Sbjct: 952 LPLIFQITPLNLTQWLMVLKISLPVILMDETLKFVARN 989
>sp|Q00779|AT2A2_FELCA Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (Calcium pump 2)
(SERCA2) (SR Ca(2+)-ATPase 2) (Calcium-transporting
ATPase sarcoplasmic reticulum type, slow twitch skeletal
muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+)
ATPase)
Length = 997
Score = 333 bits (854), Expect = 3e-91
Identities = 159/218 (72%), Positives = 186/218 (85%)
Frame = +2
Query: 2 VCIFLTAALGMPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMERPPRSPKESLISGW 181
VCIFLTAALG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM +PPR+PKE LISGW
Sbjct: 772 VCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGW 831
Query: 182 LFFRYMAIGCYVGAATVGSAAWWFMRSPDGPSVSYYQLTHHLQCALEPNDFIGVDCKVFL 361
LFFRY+AIGCYVGAATVG+AAWWF+ + GP VS+YQL+H LQC + DF GVDC +F
Sbjct: 832 LFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKDDNPDFEGVDCAIFE 891
Query: 362 NSKPMTMALSVLVLIEMLNALNSLSENQSIIKMPPWTNIWLILAITLSMSLHFLILEVGF 541
+ PMTMALSVLV IEM NALNSLSENQS+++MPPW NIWL+ +I LSMSLHFLIL V
Sbjct: 892 SPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEP 951
Query: 542 LAKVFQISPLSFSEWLTVMKFSFPVLLLDESLKVISRN 655
L +FQI+PL+ ++WL V+K S PV+L+DE+LK ++RN
Sbjct: 952 LPLIFQITPLNLTQWLMVLKISLPVILMDETLKFVARN 989
>sp|P11607|AT2A2_PIG Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (Calcium pump 2)
(SERCA2) (SR Ca(2+)-ATPase 2) (Calcium-transporting
ATPase sarcoplasmic reticulum type, slow twitch skeletal
muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+)
ATPase)
Length = 1042
Score = 333 bits (853), Expect = 4e-91
Identities = 159/218 (72%), Positives = 186/218 (85%)
Frame = +2
Query: 2 VCIFLTAALGMPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMERPPRSPKESLISGW 181
VCIFLTAALG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM +PPR+PKE LISGW
Sbjct: 772 VCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGW 831
Query: 182 LFFRYMAIGCYVGAATVGSAAWWFMRSPDGPSVSYYQLTHHLQCALEPNDFIGVDCKVFL 361
LFFRY+AIGCYVGAATVG+AAWWF+ + GP V++YQL+H LQC + DF GVDC VF
Sbjct: 832 LFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVTFYQLSHFLQCKEDNPDFEGVDCAVFE 891
Query: 362 NSKPMTMALSVLVLIEMLNALNSLSENQSIIKMPPWTNIWLILAITLSMSLHFLILEVGF 541
+ PMTMALSVLV IEM NALNSLSENQS+++MPPW NIWL+ +I LSMSLHFLIL V
Sbjct: 892 SPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEP 951
Query: 542 LAKVFQISPLSFSEWLTVMKFSFPVLLLDESLKVISRN 655
L +FQI+PL+ ++WL V+K S PV+L+DE+LK ++RN
Sbjct: 952 LPLIFQITPLNLTQWLMVLKISLPVILMDETLKFVARN 989
>sp|Q92105|AT2A1_RANES Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (Calcium pump 1)
(SERCA1) (SR Ca(2+)-ATPase 1) (Calcium-transporting
ATPase sarcoplasmic reticulum type, fast twitch skeletal
muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+)
ATPase)
Length = 994
Score = 331 bits (848), Expect = 2e-90
Identities = 158/218 (72%), Positives = 187/218 (85%)
Frame = +2
Query: 2 VCIFLTAALGMPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMERPPRSPKESLISGW 181
VCIFLTAALG+PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM+RPPRSPKE LISGW
Sbjct: 773 VCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGW 832
Query: 182 LFFRYMAIGCYVGAATVGSAAWWFMRSPDGPSVSYYQLTHHLQCALEPNDFIGVDCKVFL 361
LFFRYMAIG YVGAATVG+AAWWFM + DGP+V++YQL+H +QC + DF G +C++F
Sbjct: 833 LFFRYMAIGGYVGAATVGAAAWWFMYADDGPNVTFYQLSHFMQCTEDNPDFEGHECEIFE 892
Query: 362 NSKPMTMALSVLVLIEMLNALNSLSENQSIIKMPPWTNIWLILAITLSMSLHFLILEVGF 541
+ PMTMALSVLV IEM NALNSLSENQS+I+MPPW+N WL+ +I LSMSLHFLIL V
Sbjct: 893 SPVPMTMALSVLVTIEMCNALNSLSENQSLIRMPPWSNFWLLGSICLSMSLHFLILYVEP 952
Query: 542 LAKVFQISPLSFSEWLTVMKFSFPVLLLDESLKVISRN 655
L +F+++PL+ +W V+K SFPV+LLDE LK ++RN
Sbjct: 953 LPMIFKLTPLNVEQWFIVLKMSFPVILLDELLKFVARN 990
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,766,715
Number of Sequences: 369166
Number of extensions: 1731584
Number of successful extensions: 4837
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4664
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4817
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7115329200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)