Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_M04
(502 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P29508|SCCA1_HUMAN Squamous cell carcinoma antigen 1 (SC... 73 4e-13
sp|P48594|SCCA2_HUMAN Squamous cell carcinoma antigen 2 (SC... 69 6e-12
sp|P05544|CPI3_RAT Contrapsin-like protease inhibitor 3 pre... 64 2e-10
sp|Q60854|SPB6_MOUSE Placental thrombin inhibitor (Protease... 64 2e-10
sp|P05545|CPI1_RAT Contrapsin-like protease inhibitor 1 pre... 64 3e-10
sp|O54758|ALMS_TAMSI Alpha-1-antitrypsin-like protein CM55-... 63 3e-10
sp|P09006|CPI6_RAT Contrapsin-like protease inhibitor 6 pre... 61 1e-09
sp|Q5I2A0|SPA3G_MOUSE Serine protease inhibitor A3G (Serine... 61 1e-09
sp|P09005|SPI21_RAT Serine protease inhibitor 2.1 (SPI-2.1) 60 3e-09
sp|Q5R536|AACT_PONPY Alpha-1-antichymotrypsin precursor (ACT) 60 3e-09
>sp|P29508|SCCA1_HUMAN Squamous cell carcinoma antigen 1 (SCCA-1) (Protein T4-A)
Length = 390
Score = 72.8 bits (177), Expect = 4e-13
Identities = 40/88 (45%), Positives = 58/88 (65%), Gaps = 1/88 (1%)
Frame = +2
Query: 17 LGMIKPFSSEADFSRMTGNRELMIDDVIHKAFIDVDENGVEAAAATAVLMLGDCIFNATP 196
+GM+ F+ +AD S MTG+R L++ V+HKAF++V E G EAAAATAV+ G +T
Sbjct: 302 MGMVDIFNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSP-TSTN 360
Query: 197 IEFTCDRPFMFALIKDFTLP-LFIGHFT 277
EF C+ PF+F + ++ T LF G F+
Sbjct: 361 EEFHCNHPFLFFIRQNKTNSILFYGRFS 388
>sp|P48594|SCCA2_HUMAN Squamous cell carcinoma antigen 2 (SCCA-2) (Leupin)
Length = 390
Score = 68.9 bits (167), Expect = 6e-12
Identities = 38/88 (43%), Positives = 58/88 (65%), Gaps = 1/88 (1%)
Frame = +2
Query: 17 LGMIKPFSSEADFSRMTGNRELMIDDVIHKAFIDVDENGVEAAAATAVLMLGDCIFNATP 196
+GM+ F+ +AD S MT + L + V+HKAF++V E GVEAAAATAV+++ + +T
Sbjct: 302 MGMVNIFNGDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVV-ELSSPSTN 360
Query: 197 IEFTCDRPFMFALIKDFTLP-LFIGHFT 277
EF C+ PF+F + ++ T LF G F+
Sbjct: 361 EEFCCNHPFLFFIRQNKTNSILFYGRFS 388
>sp|P05544|CPI3_RAT Contrapsin-like protease inhibitor 3 precursor (CPI-23) (Serine
protease inhibitor 1) (SPI-1)
Length = 413
Score = 64.3 bits (155), Expect = 2e-10
Identities = 36/89 (40%), Positives = 49/89 (55%), Gaps = 1/89 (1%)
Frame = +2
Query: 14 DLGMIKPFSSEADFSRMTGNRELMIDDVIHKAFIDVDENGVEAAAATAVLMLGDCIFNAT 193
+LG+ K FS +AD SR+TG ++L + V+HKA +DVDE G EA AAT V +
Sbjct: 326 ELGIKKVFSQQADLSRITGTKDLYVSQVVHKAVLDVDETGTEATAATGVA----TVIRRQ 381
Query: 194 PIEFTCDRPFMFALI-KDFTLPLFIGHFT 277
P +RPFM + D LF+ T
Sbjct: 382 PRTLNFNRPFMVVITDMDSQSILFVAKIT 410
>sp|Q60854|SPB6_MOUSE Placental thrombin inhibitor (Protease inhibitor 6) (PI-6) (Serpin
B6)
Length = 378
Score = 63.9 bits (154), Expect = 2e-10
Identities = 39/89 (43%), Positives = 53/89 (59%), Gaps = 2/89 (2%)
Frame = +2
Query: 17 LGMIKPFSSEADFSRMTGNRELMIDDVIHKAFIDVDENGVEAAAATAVLMLGDCIFNATP 196
LGM F ADFS M+ + L + V+HKAF++V+E G EAAAATA +M C+ TP
Sbjct: 291 LGMTDAFGGRADFSGMSSKQGLFLSKVVHKAFVEVNEEGTEAAAATAGMMTVRCM-RFTP 349
Query: 197 IEFTCDRPFMFAL--IKDFTLPLFIGHFT 277
F D PF+F + +K + LF G F+
Sbjct: 350 -RFCADHPFLFFIHHVKTNGI-LFCGRFS 376
>sp|P05545|CPI1_RAT Contrapsin-like protease inhibitor 1 precursor (CPI-21)
(Kallikrein-binding protein) (KBP) (Growth
hormone-regulated proteinase inhibitor) (Serine protease
inhibitor 2) (SPI-2) (GHR-P63) (SPI-2.3) (Thyroid
hormone-regulated protein)
Length = 416
Score = 63.5 bits (153), Expect = 3e-10
Identities = 33/74 (44%), Positives = 45/74 (60%)
Frame = +2
Query: 14 DLGMIKPFSSEADFSRMTGNRELMIDDVIHKAFIDVDENGVEAAAATAVLMLGDCIFNAT 193
+LG+ K FS +AD SR+TG + L + V+HKA +DVDE G E AAATAV +
Sbjct: 326 ELGIRKIFSQQADLSRITGTKNLHVSQVVHKAVLDVDETGTEGAAATAVTAALKSLPQTI 385
Query: 194 PIEFTCDRPFMFAL 235
P+ +RPFM +
Sbjct: 386 PL-LNFNRPFMLVI 398
>sp|O54758|ALMS_TAMSI Alpha-1-antitrypsin-like protein CM55-MS precursor
Length = 413
Score = 63.2 bits (152), Expect = 3e-10
Identities = 35/85 (41%), Positives = 49/85 (57%), Gaps = 1/85 (1%)
Frame = +2
Query: 17 LGMIKPFSSEADFSRMTGNRELMIDDVIHKAFIDVDENGVEAAAATAVLMLGDCIFNATP 196
LG+ K FS+ AD S +T L++ +HKA +D+DE G EAA AT +G F + P
Sbjct: 325 LGITKVFSNAADLSGVTEEAPLIVSKALHKAVLDIDEEGTEAAGAT----VGGITFMSRP 380
Query: 197 IEFTCDRPFMFALIKDFT-LPLFIG 268
E DRPF+ + + T PLF+G
Sbjct: 381 KEVIFDRPFLVVIYEHHTKSPLFVG 405
>sp|P09006|CPI6_RAT Contrapsin-like protease inhibitor 6 precursor (CPI-26) (Serine
protease inhibitor 3) (SPI-3) (SPI-2.2)
Length = 418
Score = 61.2 bits (147), Expect = 1e-09
Identities = 31/74 (41%), Positives = 47/74 (63%)
Frame = +2
Query: 14 DLGMIKPFSSEADFSRMTGNRELMIDDVIHKAFIDVDENGVEAAAATAVLMLGDCIFNAT 193
+LG+ + FS++AD S +TG+++LM+ V+HKA +DV E G EAAAAT V +
Sbjct: 328 ELGIKEVFSTQADLSGITGDKDLMVSQVVHKAVLDVAETGTEAAAATGVKFV-PMSAKLD 386
Query: 194 PIEFTCDRPFMFAL 235
P+ DRPF+ +
Sbjct: 387 PLIIAFDRPFLMII 400
>sp|Q5I2A0|SPA3G_MOUSE Serine protease inhibitor A3G (Serine protease inhibitor 2A)
(Serpin A3G) (Serpin 2A)
Length = 440
Score = 61.2 bits (147), Expect = 1e-09
Identities = 32/75 (42%), Positives = 50/75 (66%), Gaps = 1/75 (1%)
Frame = +2
Query: 14 DLGMIKPFSSEADFSRMTGNRELMIDDVIHKAFIDVDENGVEAAAATAVLMLGDC-IFNA 190
+LG+ + FS++AD S +TG ++L + V+HKA +DV E G EAAAAT + +G C +F+
Sbjct: 318 ELGIREVFSTQADLSAITGTKDLRVSQVVHKAVLDVAETGTEAAAATGMAGVGCCAVFDF 377
Query: 191 TPIEFTCDRPFMFAL 235
I F +RPF+ +
Sbjct: 378 LEIFF--NRPFLMII 390
>sp|P09005|SPI21_RAT Serine protease inhibitor 2.1 (SPI-2.1)
Length = 214
Score = 60.1 bits (144), Expect = 3e-09
Identities = 35/89 (39%), Positives = 48/89 (53%), Gaps = 1/89 (1%)
Frame = +2
Query: 14 DLGMIKPFSSEADFSRMTGNRELMIDDVIHKAFIDVDENGVEAAAATAVLMLGDCIFNAT 193
+LG+ K FS +AD SR+TG ++L + V+HKA +DV E G EA AAT V +
Sbjct: 127 ELGIKKVFSQQADLSRITGTKDLYVSQVVHKAVLDVAETGTEATAATGVA----TVIRRQ 182
Query: 194 PIEFTCDRPFM-FALIKDFTLPLFIGHFT 277
P ++PFM F D LF+ T
Sbjct: 183 PRTLNFNQPFMVFITDMDSQSILFVAKIT 211
>sp|Q5R536|AACT_PONPY Alpha-1-antichymotrypsin precursor (ACT)
Length = 423
Score = 60.1 bits (144), Expect = 3e-09
Identities = 32/76 (42%), Positives = 50/76 (65%), Gaps = 2/76 (2%)
Frame = +2
Query: 17 LGMIKPFSSEADFSRMTGNRELMIDDVIHKAFIDVDENGVEAAAATAV--LMLGDCIFNA 190
LG+++ F+S+AD S +TG R L++ V+HKA +DV E G EA+AATAV +L +
Sbjct: 331 LGIVEAFTSKADLSGITGARNLVVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVDPM 390
Query: 191 TPIEFTCDRPFMFALI 238
T + F +RPF+ ++
Sbjct: 391 TIVRF--NRPFLMIIV 404
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,766,209
Number of Sequences: 369166
Number of extensions: 740622
Number of successful extensions: 1608
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1553
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1588
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 3168768640
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)