Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_L24
(865 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P00504|AATC_CHICK Aspartate aminotransferase, cytoplasmi... 319 5e-87
sp|P13221|AATC_RAT Aspartate aminotransferase, cytoplasmic ... 317 4e-86
sp|P05201|AATC_MOUSE Aspartate aminotransferase, cytoplasmi... 311 1e-84
sp|P00503|AATC_PIG Aspartate aminotransferase, cytoplasmic ... 310 3e-84
sp|P08906|AATC_HORSE Aspartate aminotransferase, cytoplasmi... 310 3e-84
sp|P33097|AATC_BOVIN Aspartate aminotransferase, cytoplasmi... 306 4e-83
sp|P17174|AATC_HUMAN Aspartate aminotransferase, cytoplasmi... 306 5e-83
sp|Q22067|AATC_CAEEL Probable aspartate aminotransferase, c... 293 6e-79
sp|P37833|AATC_ORYSA Aspartate aminotransferase, cytoplasmi... 272 1e-72
sp|P28734|AATC_DAUCA Aspartate aminotransferase, cytoplasmi... 271 1e-72
>sp|P00504|AATC_CHICK Aspartate aminotransferase, cytoplasmic (Transaminase A) (Glutamate
oxaloacetate transaminase 1)
Length = 412
Score = 319 bits (818), Expect = 5e-87
Identities = 146/247 (59%), Positives = 184/247 (74%)
Frame = +1
Query: 1 KEYRYWDNDKRCVNFDGMIHDINAAPNESVIVMHACAHNPTGMDLSKEQWIKLAEILKTK 180
+ YRYWD KR ++ G++ D+ AP S+ ++HACAHNPTG D + ++W ++A ++K +
Sbjct: 156 RTYRYWDAAKRGLDLQGLLDDMEKAPEFSIFILHACAHNPTGTDPTPDEWKQIAAVMKRR 215
Query: 181 KIFPIFDIAYQGFASGDLDNDAWAVRYYAEQGFELFACQSFSKNFGLYNERVGNLCIVTK 360
+FP FD AYQGFASG LD DAWAVRY+ +GFELF QSFSKNFGLYNERVGNL +V K
Sbjct: 216 CLFPFFDSAYQGFASGSLDKDAWAVRYFVSEGFELFCAQSFSKNFGLYNERVGNLSVVGK 275
Query: 361 DAAITGRVKSQMTVLVRQAWSNPPNHGGRIVATVLSNPALFAEWKGNVKLMADRVILMRQ 540
D RV SQM +VR WSNPP+ G RIVAT L++P LFAEWK NVK MADRV+LMR
Sbjct: 276 DEDNVQRVLSQMEKIVRTTWSNPPSQGARIVATTLTSPQLFAEWKDNVKTMADRVLLMRS 335
Query: 541 MLFEKLQSFGTPGSWEHVIKQIGMFSFTGLNKNQVDHMRNKYHIYMLNDGRINMCGLNNS 720
L +L+S GTPG+W H+ QIGMFSFTGLN QV++M + HIY++ GRINMCGL
Sbjct: 336 ELRSRLESLGTPGTWNHITDQIGMFSFTGLNPKQVEYMIKEKHIYLMASGRINMCGLTTK 395
Query: 721 NVEYVAR 741
N++YVA+
Sbjct: 396 NLDYVAK 402
>sp|P13221|AATC_RAT Aspartate aminotransferase, cytoplasmic (Transaminase A) (Glutamate
oxaloacetate transaminase 1)
Length = 413
Score = 317 bits (811), Expect = 4e-86
Identities = 144/246 (58%), Positives = 185/246 (75%)
Frame = +1
Query: 1 KEYRYWDNDKRCVNFDGMIHDINAAPNESVIVMHACAHNPTGMDLSKEQWIKLAEILKTK 180
+ YRYWD +KR ++ G ++D+ AP S+ V+HACAHNPTG D ++E+W ++A ++K +
Sbjct: 157 RSYRYWDAEKRGLDLQGFLNDLENAPEFSIFVLHACAHNPTGTDPTEEEWKQIAAVMKRR 216
Query: 181 KIFPIFDIAYQGFASGDLDNDAWAVRYYAEQGFELFACQSFSKNFGLYNERVGNLCIVTK 360
+FP FD AYQGFASGDL+ DAWA+RY+ +GFELF QSFSKNFGLYNERVGNL +V K
Sbjct: 217 FLFPFFDSAYQGFASGDLEKDAWAIRYFVSEGFELFCPQSFSKNFGLYNERVGNLTVVGK 276
Query: 361 DAAITGRVKSQMTVLVRQAWSNPPNHGGRIVATVLSNPALFAEWKGNVKLMADRVILMRQ 540
+ RV SQM +VR WSNPP G RIVAT LSNP LF EWKGNVK MADR++ MR
Sbjct: 277 EHDSVLRVLSQMEKIVRITWSNPPAQGARIVATTLSNPELFKEWKGNVKTMADRILTMRS 336
Query: 541 MLFEKLQSFGTPGSWEHVIKQIGMFSFTGLNKNQVDHMRNKYHIYMLNDGRINMCGLNNS 720
L +L++ TPG+W H+ +QIGMFSFTGLN QV+++ N+ HIY++ GRINMCGL
Sbjct: 337 ELRARLEALKTPGTWSHITEQIGMFSFTGLNPKQVEYLVNEKHIYLMPSGRINMCGLTTK 396
Query: 721 NVEYVA 738
N++YVA
Sbjct: 397 NLDYVA 402
>sp|P05201|AATC_MOUSE Aspartate aminotransferase, cytoplasmic (Transaminase A) (Glutamate
oxaloacetate transaminase 1)
Length = 413
Score = 311 bits (797), Expect = 1e-84
Identities = 142/246 (57%), Positives = 183/246 (74%)
Frame = +1
Query: 1 KEYRYWDNDKRCVNFDGMIHDINAAPNESVIVMHACAHNPTGMDLSKEQWIKLAEILKTK 180
+ Y YWD +KR ++ G ++D+ AP S+ V+HACAHNPTG D + EQW ++A +++ +
Sbjct: 157 RPYCYWDAEKRGLDLQGFLNDLENAPEFSIFVLHACAHNPTGTDPTPEQWKQIAAVMQRR 216
Query: 181 KIFPIFDIAYQGFASGDLDNDAWAVRYYAEQGFELFACQSFSKNFGLYNERVGNLCIVTK 360
+FP FD AYQGFASGDL+ DAWA+RY+ +GFELF QSFSKNFGLYNERVGNL +V K
Sbjct: 217 FLFPFFDSAYQGFASGDLEKDAWAIRYFVSEGFELFCAQSFSKNFGLYNERVGNLTVVGK 276
Query: 361 DAAITGRVKSQMTVLVRQAWSNPPNHGGRIVATVLSNPALFAEWKGNVKLMADRVILMRQ 540
++ RV SQM +VR WSNPP G RIVA LS+P LF EWKGNVK MADR++ MR
Sbjct: 277 ESDSVLRVLSQMEKIVRITWSNPPAQGARIVAATLSDPELFKEWKGNVKTMADRILTMRS 336
Query: 541 MLFEKLQSFGTPGSWEHVIKQIGMFSFTGLNKNQVDHMRNKYHIYMLNDGRINMCGLNNS 720
L +L++ TPG+W H+ +QIGMFSFTGLN QV+++ N+ HIY+L GRINMCGL
Sbjct: 337 ELRARLEALKTPGTWSHITEQIGMFSFTGLNPKQVEYLVNEKHIYLLPSGRINMCGLTTK 396
Query: 721 NVEYVA 738
N++YVA
Sbjct: 397 NLDYVA 402
>sp|P00503|AATC_PIG Aspartate aminotransferase, cytoplasmic (Transaminase A) (Glutamate
oxaloacetate transaminase 1)
Length = 413
Score = 310 bits (795), Expect = 3e-84
Identities = 142/246 (57%), Positives = 180/246 (73%)
Frame = +1
Query: 1 KEYRYWDNDKRCVNFDGMIHDINAAPNESVIVMHACAHNPTGMDLSKEQWIKLAEILKTK 180
+ YRYWD +KR ++ G + D+ AP S+ V+HACAHNPTG D + EQW ++A ++K +
Sbjct: 157 RSYRYWDTEKRGLDLQGFLSDLENAPEFSIFVLHACAHNPTGTDPTPEQWKQIASVMKRR 216
Query: 181 KIFPIFDIAYQGFASGDLDNDAWAVRYYAEQGFELFACQSFSKNFGLYNERVGNLCIVTK 360
+FP FD AYQGFASG+L+ DAWA+RY+ +GFELF QSFSKNFGLYNERVGNL +V K
Sbjct: 217 FLFPFFDSAYQGFASGNLEKDAWAIRYFVSEGFELFCAQSFSKNFGLYNERVGNLTVVAK 276
Query: 361 DAAITGRVKSQMTVLVRQAWSNPPNHGGRIVATVLSNPALFAEWKGNVKLMADRVILMRQ 540
+ RV SQM +VR WSNPP G RIVA LS+P LF EW GNVK MADR++ MR
Sbjct: 277 EPDSILRVLSQMEKIVRVTWSNPPAQGARIVARTLSDPELFHEWTGNVKTMADRILSMRS 336
Query: 541 MLFEKLQSFGTPGSWEHVIKQIGMFSFTGLNKNQVDHMRNKYHIYMLNDGRINMCGLNNS 720
L +L++ TPG+W H+ QIGMFSFTGLN QV+++ N+ HIY+L GRINMCGL
Sbjct: 337 ELRARLEALKTPGTWNHITDQIGMFSFTGLNPKQVEYLINEKHIYLLPSGRINMCGLTTK 396
Query: 721 NVEYVA 738
N++YVA
Sbjct: 397 NLDYVA 402
>sp|P08906|AATC_HORSE Aspartate aminotransferase, cytoplasmic (Transaminase A) (Glutamate
oxaloacetate transaminase 1)
Length = 412
Score = 310 bits (794), Expect = 3e-84
Identities = 143/246 (58%), Positives = 180/246 (73%)
Frame = +1
Query: 1 KEYRYWDNDKRCVNFDGMIHDINAAPNESVIVMHACAHNPTGMDLSKEQWIKLAEILKTK 180
+ Y YWD KR ++ G ++D+ AP S+ V+HACAHNPTG D + EQW ++A ++K +
Sbjct: 156 RSYHYWDATKRGLDLQGFLNDLENAPEFSIFVLHACAHNPTGTDPTPEQWKQIASVMKRR 215
Query: 181 KIFPIFDIAYQGFASGDLDNDAWAVRYYAEQGFELFACQSFSKNFGLYNERVGNLCIVTK 360
+FP FD AYQGFASG+LD DAWAVRY+ +GFELF QSFSKNFGLYNERVGNL +V K
Sbjct: 216 FLFPFFDSAYQGFASGNLDRDAWAVRYFVSEGFELFCAQSFSKNFGLYNERVGNLTVVAK 275
Query: 361 DAAITGRVKSQMTVLVRQAWSNPPNHGGRIVATVLSNPALFAEWKGNVKLMADRVILMRQ 540
+ RV SQM +VR WSNPP G RIVA LS+P LF EW GNVK MADR++ MR
Sbjct: 276 EPDSILRVLSQMQKIVRITWSNPPAQGARIVAFTLSDPGLFKEWTGNVKTMADRILSMRS 335
Query: 541 MLFEKLQSFGTPGSWEHVIKQIGMFSFTGLNKNQVDHMRNKYHIYMLNDGRINMCGLNNS 720
L +L++ TPG+W H+ +QIGMFSFTGLN QV+++ N+ HIY+L GRINMCGL
Sbjct: 336 ELRARLEALKTPGTWNHITEQIGMFSFTGLNPKQVEYLVNQKHIYLLPSGRINMCGLTTK 395
Query: 721 NVEYVA 738
N++YVA
Sbjct: 396 NLDYVA 401
>sp|P33097|AATC_BOVIN Aspartate aminotransferase, cytoplasmic (Transaminase A) (Glutamate
oxaloacetate transaminase 1)
Length = 413
Score = 306 bits (785), Expect = 4e-83
Identities = 141/246 (57%), Positives = 178/246 (72%)
Frame = +1
Query: 1 KEYRYWDNDKRCVNFDGMIHDINAAPNESVIVMHACAHNPTGMDLSKEQWIKLAEILKTK 180
+ Y YWD KR ++ G ++D+ AP S+ V+HACAHNPTG D + EQW ++A ++K +
Sbjct: 157 RSYHYWDAAKRGLDLQGFLNDLEKAPEFSIFVLHACAHNPTGTDPTPEQWKQIASVMKRR 216
Query: 181 KIFPIFDIAYQGFASGDLDNDAWAVRYYAEQGFELFACQSFSKNFGLYNERVGNLCIVTK 360
+FP FD AYQ FASG L+ DAWA+RY+ +GFELF QSFSKNFGLYNERVGNL +V K
Sbjct: 217 FLFPFFDSAYQAFASGSLEKDAWAIRYFVSEGFELFCAQSFSKNFGLYNERVGNLTVVAK 276
Query: 361 DAAITGRVKSQMTVLVRQAWSNPPNHGGRIVATVLSNPALFAEWKGNVKLMADRVILMRQ 540
+ RV SQM +VR WSNPP G RIVA LS+P LF EW GNVK MADR++ MR
Sbjct: 277 EPDSILRVLSQMEKIVRITWSNPPAQGARIVARTLSDPELFNEWTGNVKTMADRILTMRS 336
Query: 541 MLFEKLQSFGTPGSWEHVIKQIGMFSFTGLNKNQVDHMRNKYHIYMLNDGRINMCGLNNS 720
L +L++ TPG+W H+ +QIGMFSFTGLN QV+++ N+ HIY+L GRINMCGL
Sbjct: 337 ELRARLEALKTPGTWNHITEQIGMFSFTGLNPKQVEYLINEKHIYLLPSGRINMCGLTTK 396
Query: 721 NVEYVA 738
N+EYVA
Sbjct: 397 NLEYVA 402
>sp|P17174|AATC_HUMAN Aspartate aminotransferase, cytoplasmic (Transaminase A) (Glutamate
oxaloacetate transaminase 1)
Length = 413
Score = 306 bits (784), Expect = 5e-83
Identities = 139/246 (56%), Positives = 182/246 (73%)
Frame = +1
Query: 1 KEYRYWDNDKRCVNFDGMIHDINAAPNESVIVMHACAHNPTGMDLSKEQWIKLAEILKTK 180
+ YRYWD +KR ++ G ++D+ AP S++V+HACAHNPTG+D + EQW ++A ++K +
Sbjct: 157 RSYRYWDAEKRGLDLQGFLNDLENAPEFSIVVLHACAHNPTGIDPTPEQWKQIASVMKHR 216
Query: 181 KIFPIFDIAYQGFASGDLDNDAWAVRYYAEQGFELFACQSFSKNFGLYNERVGNLCIVTK 360
+FP FD AYQGFASG+L+ DAWA+RY+ +GFE F QSFSKNFGLYNERVGNL +V K
Sbjct: 217 FLFPFFDSAYQGFASGNLERDAWAIRYFVSEGFEFFCAQSFSKNFGLYNERVGNLTVVGK 276
Query: 361 DAAITGRVKSQMTVLVRQAWSNPPNHGGRIVATVLSNPALFAEWKGNVKLMADRVILMRQ 540
+ +V SQM +VR WSNPP G RIVA+ LSNP LF EW GNVK MADR++ MR
Sbjct: 277 EPESILQVLSQMEKIVRITWSNPPAQGARIVASTLSNPELFEEWTGNVKTMADRILTMRS 336
Query: 541 MLFEKLQSFGTPGSWEHVIKQIGMFSFTGLNKNQVDHMRNKYHIYMLNDGRINMCGLNNS 720
L +L++ TPG+W H+ QIGMFSFTGLN QV+++ N+ HIY+L GRIN+ GL
Sbjct: 337 ELRARLEALKTPGTWNHITDQIGMFSFTGLNPKQVEYLVNEKHIYLLPSGRINVSGLTTK 396
Query: 721 NVEYVA 738
N++YVA
Sbjct: 397 NLDYVA 402
>sp|Q22067|AATC_CAEEL Probable aspartate aminotransferase, cytoplasmic (Transaminase A)
(Glutamate oxaloacetate transaminase-1)
Length = 408
Score = 293 bits (749), Expect = 6e-79
Identities = 129/246 (52%), Positives = 178/246 (72%)
Frame = +1
Query: 4 EYRYWDNDKRCVNFDGMIHDINAAPNESVIVMHACAHNPTGMDLSKEQWIKLAEILKTKK 183
+Y +WD D + V+ + + D+ +AP +SVI++H CAHNPTGMD ++EQW +AE++K K
Sbjct: 150 DYTFWDYDNKRVHIEKFLSDLESAPEKSVIILHGCAHNPTGMDPTQEQWKLVAEVIKRKN 209
Query: 184 IFPIFDIAYQGFASGDLDNDAWAVRYYAEQGFELFACQSFSKNFGLYNERVGNLCIVTKD 363
+F FDIAYQGFASGD DAWA+RY+ +QG E+ QSF+KNFGLYNERVGNL +V +
Sbjct: 210 LFTFFDIAYQGFASGDPAADAWAIRYFVDQGMEMVVSQSFAKNFGLYNERVGNLTVVVNN 269
Query: 364 AAITGRVKSQMTVLVRQAWSNPPNHGGRIVATVLSNPALFAEWKGNVKLMADRVILMRQM 543
A+ +SQM++++R WSNPP HG RIV VL+ PA +W +++ M+ R+ MR
Sbjct: 270 PAVIAGFQSQMSLVIRANWSNPPAHGARIVHKVLTTPARREQWNQSIQAMSSRIKQMRAA 329
Query: 544 LFEKLQSFGTPGSWEHVIKQIGMFSFTGLNKNQVDHMRNKYHIYMLNDGRINMCGLNNSN 723
L L GTPG+W+H+I+QIGMFS+TGL QVDH+ + +++L DGRIN+CGLN N
Sbjct: 330 LLRHLMDLGTPGTWDHIIQQIGMFSYTGLTSAQVDHLIANHKVFLLRDGRINICGLNTKN 389
Query: 724 VEYVAR 741
VEYVA+
Sbjct: 390 VEYVAK 395
>sp|P37833|AATC_ORYSA Aspartate aminotransferase, cytoplasmic (Transaminase A)
Length = 407
Score = 272 bits (695), Expect = 1e-72
Identities = 124/246 (50%), Positives = 178/246 (72%)
Frame = +1
Query: 1 KEYRYWDNDKRCVNFDGMIHDINAAPNESVIVMHACAHNPTGMDLSKEQWIKLAEILKTK 180
+ YRY+D R ++F G++ D+ +AP+ +++++HACAHNPTG+D + +QW ++ +++++K
Sbjct: 151 RSYRYYDPATRGLDFQGLLEDLGSAPSGAIVLLHACAHNPTGVDPTLDQWEQIRQLMRSK 210
Query: 181 KIFPIFDIAYQGFASGDLDNDAWAVRYYAEQGFELFACQSFSKNFGLYNERVGNLCIVTK 360
+ P FD AYQGFASG LD DA +VR + G EL QS++KN GLY ERVG L IV
Sbjct: 211 ALLPFFDSAYQGFASGSLDQDAQSVRMFVADGGELLMAQSYAKNMGLYGERVGALSIVCG 270
Query: 361 DAAITGRVKSQMTVLVRQAWSNPPNHGGRIVATVLSNPALFAEWKGNVKLMADRVILMRQ 540
A + RV+SQ+ +++R +SNPP HG IVAT+L + A+F EW +K MADR+I MRQ
Sbjct: 271 SADVAVRVESQLKLVIRPMYSNPPIHGASIVATILKDSAMFNEWTVELKGMADRIISMRQ 330
Query: 541 MLFEKLQSFGTPGSWEHVIKQIGMFSFTGLNKNQVDHMRNKYHIYMLNDGRINMCGLNNS 720
LF+ L++ TPG W H+IKQIGMF+FTGLN +QV MR +YHIYM +DGRI+M GL+
Sbjct: 331 QLFDALKTRETPGDWSHIIKQIGMFTFTGLNSDQVAFMRQEYHIYMTSDGRISMAGLSGR 390
Query: 721 NVEYVA 738
+ ++A
Sbjct: 391 TIPHLA 396
>sp|P28734|AATC_DAUCA Aspartate aminotransferase, cytoplasmic (Transaminase A)
Length = 405
Score = 271 bits (694), Expect = 1e-72
Identities = 124/246 (50%), Positives = 178/246 (72%)
Frame = +1
Query: 1 KEYRYWDNDKRCVNFDGMIHDINAAPNESVIVMHACAHNPTGMDLSKEQWIKLAEILKTK 180
K YRY++ + R ++F+GM+ D+ +AP +++++HACAHNPTG+D + EQW ++ +++++K
Sbjct: 149 KTYRYYNPETRGLDFEGMLEDLGSAPLGAIVLLHACAHNPTGVDPTIEQWEQIRQLMRSK 208
Query: 181 KIFPIFDIAYQGFASGDLDNDAWAVRYYAEQGFELFACQSFSKNFGLYNERVGNLCIVTK 360
+ P FD AYQGFASG LD DA +VR + G E A QS++KN GLY ERVG L IV K
Sbjct: 209 SLLPFFDSAYQGFASGSLDADAQSVRIFVADGGECLAAQSYAKNMGLYGERVGALSIVCK 268
Query: 361 DAAITGRVKSQMTVLVRQAWSNPPNHGGRIVATVLSNPALFAEWKGNVKLMADRVILMRQ 540
A + +V+SQ+ +++R +S+PP HG IVA +L + L+ EW +K MADR+I MRQ
Sbjct: 269 TADVASKVESQLKLVIRPMYSSPPLHGASIVAAILKDGDLYNEWTLELKAMADRIISMRQ 328
Query: 541 MLFEKLQSFGTPGSWEHVIKQIGMFSFTGLNKNQVDHMRNKYHIYMLNDGRINMCGLNNS 720
LF LQ+ GTPG W H++KQIGMF+FTGLN QV M N+YHIY+ +DGRI+M GL++
Sbjct: 329 ELFNALQAKGTPGDWSHIVKQIGMFTFTGLNSEQVTFMTNEYHIYLTSDGRISMAGLSSR 388
Query: 721 NVEYVA 738
V ++A
Sbjct: 389 TVPHLA 394
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 98,912,163
Number of Sequences: 369166
Number of extensions: 2049538
Number of successful extensions: 4797
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4649
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4776
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8582957970
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)