Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_L02
(732 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q7T339|CHMP5_BRARE Charged multivesicular body protein 5... 193 3e-49
sp|Q9D7S9|CHMP5_MOUSE Charged multivesicular body protein 5... 187 2e-47
sp|Q5FW29|CHMP5_XENTR Charged multivesicular body protein 5... 186 7e-47
sp|Q5RBR3|CHMP5_PONPY Charged multivesicular body protein 5... 185 1e-46
sp|Q6DD52|CHMP5_XENLA Charged multivesicular body protein 5... 184 3e-46
sp|Q03390|VPS60_YEAST Vacuolar protein sorting-associated p... 56 9e-08
sp|Q6FW96|SNF7_CANGA Vacuolar sorting protein SNF7 (Vacuola... 44 6e-04
sp|Q6CJL0|SNF7_KLULA Vacuolar sorting protein SNF7 (Vacuola... 43 0.001
sp|Q9P7F7|SNF7_SCHPO Vacuolar sorting protein snf7 (Vacuola... 41 0.003
sp|Q753W3|SNF7_ASHGO Vacuolar sorting protein SNF7 (Vacuola... 41 0.003
>sp|Q7T339|CHMP5_BRARE Charged multivesicular body protein 5 (Chromatin modifying protein
5)
Length = 220
Score = 193 bits (491), Expect = 3e-49
Identities = 100/193 (51%), Positives = 126/193 (65%), Gaps = 1/193 (0%)
Frame = +1
Query: 49 SRGESVDKKIQRLDVELAKYREQMKKMRDGPAKNMIKQKALRVLKQKRVYENQREQLSNQ 228
SR ESVDKKI RLD EL KY++QMKKMRDGP+KNM+KQKA+RVLKQKR+YE QR+QL Q
Sbjct: 26 SRAESVDKKIARLDAELMKYKDQMKKMRDGPSKNMVKQKAMRVLKQKRMYEGQRDQLMQQ 85
Query: 229 SFNLEQANFAIQTVKDTKSQVDAMKIGVKSFKKEFKNMNXXXXXXXXXXXXXMTEQASEI 408
SFN+EQAN+ IQT+KDTK+ V+AMKIG K KK +KN+ M E A+E+
Sbjct: 86 SFNMEQANYTIQTLKDTKTTVEAMKIGAKEMKKAYKNVKIDQIEDLQDQLEDMMEDANEV 145
Query: 409 QEVLGRTYDMPXXXXXXXXXXXXXXXXXIGI-GEGSYLDDALNVPGVPSTNPGESTVAPG 585
QE L R+Y P + + + SYLD+A + P +P PG+ T
Sbjct: 146 QEALSRSYGTPEIDEDDLEAELDALGDELLLDDDNSYLDEASSAPAIPEGAPGDRTTNRD 205
Query: 586 ELAVDEFGLPKIP 624
+ VDEFGLP+IP
Sbjct: 206 GVLVDEFGLPQIP 218
>sp|Q9D7S9|CHMP5_MOUSE Charged multivesicular body protein 5 (Chromatin modifying protein
5) (SNF7 domain-containing protein 2)
sp|Q4QQV8|CHMP5_RAT Charged multivesicular body protein 5 (Chromatin modifying protein
5)
Length = 219
Score = 187 bits (475), Expect = 2e-47
Identities = 100/193 (51%), Positives = 126/193 (65%), Gaps = 1/193 (0%)
Frame = +1
Query: 49 SRGESVDKKIQRLDVELAKYREQMKKMRDGPAKNMIKQKALRVLKQKRVYENQREQLSNQ 228
SR ES+DKKI RLD EL KY++Q+KKMR+GPAKNM+KQKALRVLKQKR+YE QR+ L+ Q
Sbjct: 26 SRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQQ 85
Query: 229 SFNLEQANFAIQTVKDTKSQVDAMKIGVKSFKKEFKNMNXXXXXXXXXXXXXMTEQASEI 408
SFN+EQAN+ IQ++KDTK+ VDAMK+GVK KK +K + M E A+EI
Sbjct: 86 SFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKEVKIDQIEDLQDQLEDMMEDANEI 145
Query: 409 QEVLGRTYDMPXXXXXXXXXXXXXXXXXIGIGE-GSYLDDALNVPGVPSTNPGESTVAPG 585
QE LGR+Y P + E SYLD+A + P +P P ++ G
Sbjct: 146 QEALGRSYGTPELDEDDLEAELDALGDELLADEDSSYLDEAASAPAIPEGVPTDTKNKDG 205
Query: 586 ELAVDEFGLPKIP 624
L VDEFGLP+IP
Sbjct: 206 VL-VDEFGLPQIP 217
>sp|Q5FW29|CHMP5_XENTR Charged multivesicular body protein 5 (Chromatin modifying protein
5)
Length = 219
Score = 186 bits (471), Expect = 7e-47
Identities = 98/193 (50%), Positives = 125/193 (64%), Gaps = 1/193 (0%)
Frame = +1
Query: 49 SRGESVDKKIQRLDVELAKYREQMKKMRDGPAKNMIKQKALRVLKQKRVYENQREQLSNQ 228
SR ES+DKKI RLD EL KY++QMKKMR+GP+KNM+KQKALRVLKQKR+YE QR+ L+ Q
Sbjct: 26 SRSESIDKKISRLDAELVKYKDQMKKMREGPSKNMVKQKALRVLKQKRMYEQQRDNLNQQ 85
Query: 229 SFNLEQANFAIQTVKDTKSQVDAMKIGVKSFKKEFKNMNXXXXXXXXXXXXXMTEQASEI 408
SFN+EQ N+AIQ++KDTK+ VDAMK+G K KK +K + M E A+EI
Sbjct: 86 SFNMEQTNYAIQSLKDTKTTVDAMKVGAKEMKKAYKQVKIDQIEDLQDQLEDMMENANEI 145
Query: 409 QEVLGRTYDMPXXXXXXXXXXXXXXXXXIGIGEG-SYLDDALNVPGVPSTNPGESTVAPG 585
QE L R+Y P + + + SYLD+A + P +P P +S G
Sbjct: 146 QEALSRSYGTPEIDEDDLEAELDALGDELLLDDDTSYLDEAASAPAIPEGVPNDSKNKDG 205
Query: 586 ELAVDEFGLPKIP 624
L VDEFGLP+IP
Sbjct: 206 VL-VDEFGLPQIP 217
>sp|Q5RBR3|CHMP5_PONPY Charged multivesicular body protein 5 (Chromatin modifying protein
5)
sp|Q9NZZ3|CHMP5_HUMAN Charged multivesicular body protein 5 (Chromatin modifying protein
5) (Vacuolar protein sorting 60) (Vps60) (hVps60) (SNF7
domain-containing protein 2)
Length = 219
Score = 185 bits (469), Expect = 1e-46
Identities = 99/193 (51%), Positives = 125/193 (64%), Gaps = 1/193 (0%)
Frame = +1
Query: 49 SRGESVDKKIQRLDVELAKYREQMKKMRDGPAKNMIKQKALRVLKQKRVYENQREQLSNQ 228
SR ES+DKKI RLD EL KY++Q+KKMR+GPAKNM+KQKALRVLKQKR+YE QR+ L+ Q
Sbjct: 26 SRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQQ 85
Query: 229 SFNLEQANFAIQTVKDTKSQVDAMKIGVKSFKKEFKNMNXXXXXXXXXXXXXMTEQASEI 408
SFN+EQAN+ IQ++KDTK+ VDAMK+GVK KK +K + M E A+EI
Sbjct: 86 SFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEI 145
Query: 409 QEVLGRTYDMPXXXXXXXXXXXXXXXXXIGIGE-GSYLDDALNVPGVPSTNPGESTVAPG 585
QE L R+Y P + E SYLD+A + P +P P ++ G
Sbjct: 146 QEALSRSYGTPELDEDDLEAELDALGDELLADEDSSYLDEAASAPAIPEGVPTDTKNKDG 205
Query: 586 ELAVDEFGLPKIP 624
L VDEFGLP+IP
Sbjct: 206 VL-VDEFGLPQIP 217
>sp|Q6DD52|CHMP5_XENLA Charged multivesicular body protein 5 (Chromatin modifying protein
5)
Length = 219
Score = 184 bits (466), Expect = 3e-46
Identities = 97/192 (50%), Positives = 124/192 (64%), Gaps = 1/192 (0%)
Frame = +1
Query: 52 RGESVDKKIQRLDVELAKYREQMKKMRDGPAKNMIKQKALRVLKQKRVYENQREQLSNQS 231
R ES++KKI RLD EL KY++QMKKMR+GP+KNM+KQKALRVLKQKR+YE QR+ L+ QS
Sbjct: 27 RAESIEKKISRLDAELIKYKDQMKKMREGPSKNMVKQKALRVLKQKRMYEQQRDNLNQQS 86
Query: 232 FNLEQANFAIQTVKDTKSQVDAMKIGVKSFKKEFKNMNXXXXXXXXXXXXXMTEQASEIQ 411
FN+EQAN+ IQT+KDTK+ VDAMK+G K KK +K + M E A+EIQ
Sbjct: 87 FNMEQANYTIQTLKDTKTTVDAMKVGAKEMKKAYKQVKIDQIEDLQDQLEDMMENANEIQ 146
Query: 412 EVLGRTYDMPXXXXXXXXXXXXXXXXXIGIGEG-SYLDDALNVPGVPSTNPGESTVAPGE 588
E L R+Y P + + + SYLD+A + P +P P +S G
Sbjct: 147 EALSRSYGTPEIDEDDLEAELDALGDELLLDDDTSYLDEAASAPAIPEGVPNDSKNKDGV 206
Query: 589 LAVDEFGLPKIP 624
L VDEFGLP+IP
Sbjct: 207 L-VDEFGLPQIP 217
>sp|Q03390|VPS60_YEAST Vacuolar protein sorting-associated protein VPS60
Length = 262
Score = 56.2 bits (134), Expect = 9e-08
Identities = 29/126 (23%), Positives = 67/126 (53%), Gaps = 5/126 (3%)
Frame = +1
Query: 58 ESVDKKIQRLDVELAKYREQMKKM-----RDGPAKNMIKQKALRVLKQKRVYENQREQLS 222
+S+ +I +LD ++A+ Q++ + R + ++++AL++L +++ EN ++ L
Sbjct: 62 QSLSNRISQLDTQIAQLNFQLQNIQKNLQRSNNKQPSLRKQALKILNKRKQLENMKDSLD 121
Query: 223 NQSFNLEQANFAIQTVKDTKSQVDAMKIGVKSFKKEFKNMNXXXXXXXXXXXXXMTEQAS 402
+QS+++ QA +++T ++A+K + K ++ +N + EQ
Sbjct: 122 SQSWSMTQAQLTNDNLQNTMITINALKQTNNAMKAQYGKINIDKLQDMQDEMLDLIEQGD 181
Query: 403 EIQEVL 420
E+QEVL
Sbjct: 182 ELQEVL 187
>sp|Q6FW96|SNF7_CANGA Vacuolar sorting protein SNF7 (Vacuolar protein sorting-associated
protein VPS32)
Length = 228
Score = 43.5 bits (101), Expect = 6e-04
Identities = 31/121 (25%), Positives = 50/121 (41%)
Frame = +1
Query: 64 VDKKIQRLDVELAKYREQMKKMRDGPAKNMIKQKALRVLKQKRVYENQREQLSNQSFNLE 243
+ KK L ++ + +K K M K LK+K+VYE Q +L +Q +LE
Sbjct: 31 LSKKQAHLQGQITAQENEARKFLTRGNKTMAKN----ALKKKKVYEGQLVKLESQMDSLE 86
Query: 244 QANFAIQTVKDTKSQVDAMKIGVKSFKKEFKNMNXXXXXXXXXXXXXMTEQASEIQEVLG 423
Q F+I++ + AMK G K+ K ++ E EI + +
Sbjct: 87 QQLFSIESANLNLETMRAMKQGAKAMKSIHSGLDIDRVDETMDEIREQVELGEEISDAIS 146
Query: 424 R 426
R
Sbjct: 147 R 147
>sp|Q6CJL0|SNF7_KLULA Vacuolar sorting protein SNF7 (Vacuolar protein sorting-associated
protein VPS32)
Length = 232
Score = 42.7 bits (99), Expect = 0.001
Identities = 29/121 (23%), Positives = 54/121 (44%)
Frame = +1
Query: 64 VDKKIQRLDVELAKYREQMKKMRDGPAKNMIKQKALRVLKQKRVYENQREQLSNQSFNLE 243
++KK L ++ + ++ KK KN K LK+K++YE+Q ++L +Q +L+
Sbjct: 30 LNKKQAHLQTQIDQQQQLAKKSLQSGNKNNAKT----YLKKKKLYESQLDKLQSQIDSLD 85
Query: 244 QANFAIQTVKDTKSQVDAMKIGVKSFKKEFKNMNXXXXXXXXXXXXXMTEQASEIQEVLG 423
Q ++I+ + AMK G + K K ++ E EI E +
Sbjct: 86 QQLYSIENANLNLETLKAMKQGASAMKNIHKGLDLDKVDDTMDEIREQVELNQEISEAIS 145
Query: 424 R 426
+
Sbjct: 146 K 146
>sp|Q9P7F7|SNF7_SCHPO Vacuolar sorting protein snf7 (Vacuolar protein sorting-associated
protein vps32)
Length = 222
Score = 41.2 bits (95), Expect = 0.003
Identities = 28/93 (30%), Positives = 49/93 (52%)
Frame = +1
Query: 67 DKKIQRLDVELAKYREQMKKMRDGPAKNMIKQKALRVLKQKRVYENQREQLSNQSFNLEQ 246
DKK + L+ ++A EQ + R N K+ AL LK+K+++EN+ ++ N+EQ
Sbjct: 32 DKKEEVLERQIA---EQTEIARKNATTN--KRLALTALKRKKMHENELVKIEGSRNNIEQ 86
Query: 247 ANFAIQTVKDTKSQVDAMKIGVKSFKKEFKNMN 345
F+IQ + AM+ G ++ K + M+
Sbjct: 87 QLFSIQNANLNFETLQAMRQGAEAMKSIQRGMD 119
>sp|Q753W3|SNF7_ASHGO Vacuolar sorting protein SNF7 (Vacuolar protein sorting-associated
protein VPS32)
Length = 237
Score = 41.2 bits (95), Expect = 0.003
Identities = 29/121 (23%), Positives = 49/121 (40%)
Frame = +1
Query: 64 VDKKIQRLDVELAKYREQMKKMRDGPAKNMIKQKALRVLKQKRVYENQREQLSNQSFNLE 243
+ KK L ++ E + KNM K LK+K+V+E+Q ++ Q +LE
Sbjct: 32 LSKKQAHLQTQMTSQEESARHFLSKGNKNMAKA----ALKRKKVFESQLLKIDKQVDSLE 87
Query: 244 QANFAIQTVKDTKSQVDAMKIGVKSFKKEFKNMNXXXXXXXXXXXXXMTEQASEIQEVLG 423
Q ++I+ + AMK G + K + ++ E EI E +
Sbjct: 88 QQLYSIENANLNLETMKAMKQGASAMKHIHEGLDVERVDETMDEIREQVELGEEISEAIS 147
Query: 424 R 426
R
Sbjct: 148 R 148
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 74,921,567
Number of Sequences: 369166
Number of extensions: 1358244
Number of successful extensions: 3964
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3740
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3928
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6534486000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)