Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_J08
(736 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P21783|NOTCH_XENLA Neurogenic locus notch protein homolo... 37 0.055
sp|P98157|LRP1_CHICK Low-density lipoprotein receptor-relat... 34 0.35
sp|P09208|INSR_DROME Insulin-like receptor precursor (DIR) ... 34 0.35
sp|P46749|RM05_PROWI Mitochondrial 60S ribosomal protein L5 34 0.46
sp|P46023|GR101_LYMST G-protein coupled receptor GRL101 pre... 33 0.60
sp|P29166|PHF1_CLOPA Periplasmic [Fe] hydrogenase 1 (Fe-onl... 33 0.60
sp|Q03185|TS11_GIALA Major surface trophozoite antigen 11 p... 33 1.0
sp|P47722|DEOC_MYCPI Deoxyribose-phosphate aldolase (Phosph... 32 1.3
sp|Q9Y219|JAG2_HUMAN Jagged-2 precursor (Jagged2) (HJ2) 32 1.8
sp|Q9DA37|SAMD8_MOUSE Sphingomyelin synthase-related 1 (Ste... 32 2.3
>sp|P21783|NOTCH_XENLA Neurogenic locus notch protein homolog precursor (XOTCH protein)
Length = 2524
Score = 37.0 bits (84), Expect = 0.055
Identities = 47/215 (21%), Positives = 75/215 (34%), Gaps = 30/215 (13%)
Frame = +3
Query: 90 NKLDNINCKC---VTNIQTDDKLINCTETPKIEYATNKKEYENGIYDIVTNTSERKENCE 260
N+ + C C T D+ + C +P + T ++ + YD +NCE
Sbjct: 196 NEFGSYRCTCQNRFTGRNCDEPYVPCNPSPCLNGGTCRQTDDTS-YDCTCLPGFSGQNCE 254
Query: 261 CVKKSSTTYKLISCSNNYQRI--KIPNSIYDYKCESPKP-------PPVVETKCLPDSNI 413
+ C +N R + + Y C+ P V E + +P++
Sbjct: 255 --------ENIDDCPSNNCRNGGTCVDGVNTYNCQCPPDWTGQYCTEDVDECQLMPNA-- 304
Query: 414 SLSNGRFNVTTYKIINDKCVSDSNIVPCSECTKQYCAENRESCIGVKCNEEAEAH----- 578
NG TY N CV+ T + C+EN + C C+ A H
Sbjct: 305 -CQNGGTCHNTYGGYNCVCVNG--------WTGEDCSENIDDCANAACHSGATCHDRVAS 355
Query: 579 ----CP-----ITCKICEPCPSN----ARDCETNP 644
CP + C + C SN +C+TNP
Sbjct: 356 FYCECPHGRTGLLCHLDNACISNPCNEGSNCDTNP 390
>sp|P98157|LRP1_CHICK Low-density lipoprotein receptor-related protein 1 precursor (LRP)
(Alpha-2-macroglobulin receptor) (A2MR)
Length = 4543
Score = 34.3 bits (77), Expect = 0.35
Identities = 15/49 (30%), Positives = 28/49 (57%)
Frame = +3
Query: 201 YENGIYDIVTNTSERKENCECVKKSSTTYKLISCSNNYQRIKIPNSIYD 347
+E+ YD +TNT+ + +C++ S+TY +C +Q++ NS D
Sbjct: 3776 HEHKSYDCMTNTTMCGDEAQCIQAQSSTY--CTCRRGFQKVPDKNSCQD 3822
>sp|P09208|INSR_DROME Insulin-like receptor precursor (DIR) (DInr) (dIRH) [Contains:
Insulin-like receptor alpha subunit; Insulin-like
receptor beta 1 subunit; Insulin-like receptor beta 2
subunit]
Length = 2144
Score = 34.3 bits (77), Expect = 0.35
Identities = 27/89 (30%), Positives = 33/89 (37%), Gaps = 11/89 (12%)
Frame = +3
Query: 402 DSNISLSNGRFNVTTYKIINDKCVS-----DSNIVPCSECTKQYCAENRESCIGVKCNEE 566
+S IS N FN I D C DS V +EC E G+ N +
Sbjct: 562 ESCISCRNVSFN----NICMDSCPKGYYQFDSRCVTANECITLTKFETNSVYSGIPYNGQ 617
Query: 567 AEAHCPI------TCKICEPCPSNARDCE 635
HCP ++CEPCP D E
Sbjct: 618 CITHCPTGYQKSENKRMCEPCPGGKCDKE 646
>sp|P46749|RM05_PROWI Mitochondrial 60S ribosomal protein L5
Length = 231
Score = 33.9 bits (76), Expect = 0.46
Identities = 36/150 (24%), Positives = 60/150 (40%), Gaps = 11/150 (7%)
Frame = +3
Query: 78 TTTKNKLDNINCKCVTNIQTDDKLINCTETPKIEYATNKKEYENG------IYDIVTNTS 239
TT + NI C+ + Q ++ C KI T+ K Y + + +
Sbjct: 39 TTLQKYYKNIVCQDLCLKQDYKNIMECVSLNKIVCNTSSKHYAGEKESILPAFTALEMIT 98
Query: 240 ERKENCECVKKSSTTYKL-----ISCSNNYQRIKIPNSIYDYKCESPKPPPVVETKCLPD 404
+K C KKS +T+KL + C N+ + N++Y + K +V T+
Sbjct: 99 GQKPKYTCAKKSISTFKLRQNQILGCKNSLR----GNTMYRF---LEKYISIVSTRIKDW 151
Query: 405 SNISLSNGRFNVTTYKIINDKCVSDSNIVP 494
S S+ + N T D V +SN+ P
Sbjct: 152 SENYSSSNKSNSLTTAYNKDYVVLNSNLFP 181
>sp|P46023|GR101_LYMST G-protein coupled receptor GRL101 precursor
Length = 1115
Score = 33.5 bits (75), Expect = 0.60
Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 5/68 (7%)
Frame = +3
Query: 456 INDKCVSDSNIVPCSE---CTKQYCAENRESCIGVKCNEEAEAHCPITCKICEPCP--SN 620
I+ +C S + V S+ C CA N +SC+ C EE + C CP S+
Sbjct: 382 ISKRCDSVHDCVDWSDEMNCENHQCAANMKSCLSGHCIEEHK-----WCNFHRECPDGSD 436
Query: 621 ARDCETNP 644
+DC+ P
Sbjct: 437 EKDCDPRP 444
>sp|P29166|PHF1_CLOPA Periplasmic [Fe] hydrogenase 1 (Fe-only hydrogenase) (CpI)
Length = 574
Score = 33.5 bits (75), Expect = 0.60
Identities = 36/143 (25%), Positives = 55/143 (38%), Gaps = 13/143 (9%)
Frame = +3
Query: 117 CVTNIQTDDKLINCTETPKIEYATNKKEYENGIYDIVTNTSERKENCECVKKSSTTYKLI 296
C T I+ D +IN E ++ I++ R+ENCE +K +I
Sbjct: 62 CDTLIE-DGMIINTNSDAVNEKIKSRISQLLDIHEFKCGPCNRRENCEFLKL------VI 114
Query: 297 SCSNNYQRIKIPNSIYDYKCESPKPPPVVETKCLPDSNISLSNGRFNVTTY--KIIN--- 461
+ +P +Y E K V TKCL + G+ N TY K +N
Sbjct: 115 KYKARASKPFLPKDKTEYVDERSKSLTVDRTKCLLCGRCVNACGK-NTETYAMKFLNKNG 173
Query: 462 --------DKCVSDSNIVPCSEC 506
+KC D+N + C +C
Sbjct: 174 KTIIGAEDEKCFDDTNCLLCGQC 196
>sp|Q03185|TS11_GIALA Major surface trophozoite antigen 11 precursor
Length = 667
Score = 32.7 bits (73), Expect = 1.0
Identities = 48/219 (21%), Positives = 79/219 (36%), Gaps = 8/219 (3%)
Frame = +3
Query: 3 QKCACSLSCPGETVSTACVDGKIKTTTTKNKLDNINCKCVTNIQTDDKLINCTETPKIEY 182
Q C S PG T+ T + + N T D +++C+E I
Sbjct: 72 QVCGKMSSVPGNTLCTTVSPDGVCSVAANEYFVPPNADA-----THDSVVSCSEETPIHL 126
Query: 183 ATNKKEYENGIYDIVTNTSERKENCECVKKSSTTYKLISCSNNYQRIKIPNSIYDYKCES 362
A NK+ G+ T ++ + + K++T K C+ + + P+ CE
Sbjct: 127 ANNKQYI--GVAGCATCSAPKAPGEDNTPKAATCTK---CAAGF--LHTPSEGLS-SCEE 178
Query: 363 PKPPPVVETKCLPDSN---ISLSNGRFNVTTYKIIND--KCV---SDSNIVPCSECTKQY 518
P +S S + G K I D KC+ + N + C +C+
Sbjct: 179 TCPEGYFGHTATAESKKTCKSCTGGSSEAPNVKGIGDCLKCMYNEASGNTLTCEKCS--- 235
Query: 519 CAENRESCIGVKCNEEAEAHCPITCKICEPCPSNARDCE 635
A+ + S CN+ T + C C S+ DCE
Sbjct: 236 -AQKKPSLDKTSCND-------CTGQNCAFCSSSGGDCE 266
>sp|P47722|DEOC_MYCPI Deoxyribose-phosphate aldolase (Phosphodeoxyriboaldolase)
(Deoxyriboaldolase) (DERA)
Length = 220
Score = 32.3 bits (72), Expect = 1.3
Identities = 21/74 (28%), Positives = 32/74 (43%), Gaps = 8/74 (10%)
Frame = +3
Query: 144 KLINCTETPKIEYATNKKEYENGI--------YDIVTNTSERKENCECVKKSSTTYKLIS 299
K+ P + +T +K YE I D+V N SE KENC CV YK +
Sbjct: 56 KICTVVGFPLGQTSTKQKVYETKIAIKEGADEIDMVLNISEFKENCACVVNEIRKYKKV- 114
Query: 300 CSNNYQRIKIPNSI 341
C ++ + ++
Sbjct: 115 CKKKILKVIVETAL 128
>sp|Q9Y219|JAG2_HUMAN Jagged-2 precursor (Jagged2) (HJ2)
Length = 1238
Score = 32.0 bits (71), Expect = 1.8
Identities = 21/66 (31%), Positives = 26/66 (39%), Gaps = 2/66 (3%)
Frame = +3
Query: 459 NDKCVSDSNIVPCSECTKQYCAENRESCIGVKCNEEAEAHCPITCKICEPCPS--NARDC 632
N C+ DS T YC EN + C+G C + C CPS C
Sbjct: 619 NFSCICDSGF------TGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCF-CPSGWEGELC 671
Query: 633 ETNPFD 650
+TNP D
Sbjct: 672 DTNPND 677
>sp|Q9DA37|SAMD8_MOUSE Sphingomyelin synthase-related 1 (Sterile alpha motif domain
containing 8)
Length = 478
Score = 31.6 bits (70), Expect = 2.3
Identities = 21/61 (34%), Positives = 26/61 (42%)
Frame = -3
Query: 605 FADFACYWTMSFSFFIAFYTNTRFSIFCTVLLCTFATWHYVRIAHTFIINNFIRCNVKST 426
F A + S FIAFY TR ++ L T A R F + +F CNV T
Sbjct: 399 FFILAAHEHYSIDVFIAFYITTRLFLYYHTLANTRAYHQSRRARIWFPMFSFFECNVNGT 458
Query: 425 V 423
V
Sbjct: 459 V 459
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,102,056
Number of Sequences: 369166
Number of extensions: 1615958
Number of successful extensions: 5488
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5080
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5470
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6582889600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)