Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_I08
(725 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9NRR5|UBQL4_HUMAN Ubiquilin-4 (Ataxin-1 ubiquitin-like ... 73 7e-13
sp|Q99NB8|UBQL4_MOUSE Ubiquilin-4 (Ataxin-1 ubiquitin-like ... 72 1e-12
sp|Q9UHD9|UBQL2_HUMAN Ubiquilin-2 (Protein linking IAP with... 56 9e-08
sp|Q9UMX0|UBQL1_HUMAN Ubiquilin-1 (Protein linking IAP with... 55 1e-07
sp|Q8R317|UBQL1_MOUSE Ubiquilin-1 (Protein linking IAP with... 54 4e-07
sp|Q9JJP9|UBQL1_RAT Ubiquilin-1 (Protein linking IAP with c... 54 4e-07
sp|Q9QZM0|UBQL2_MOUSE Ubiquilin-2 (Protein linking IAP with... 54 6e-07
sp|Q9H347|UBQL3_HUMAN Ubiquilin-3 49 1e-05
sp|Q8C5U9|UBQL3_MOUSE Ubiquilin-3 44 6e-04
sp|O74345|UCP3_SCHPO UBA-domain containing protein 3 37 0.070
>sp|Q9NRR5|UBQL4_HUMAN Ubiquilin-4 (Ataxin-1 ubiquitin-like interacting protein A1U)
Length = 601
Score = 73.2 bits (178), Expect = 7e-13
Identities = 56/178 (31%), Positives = 72/178 (40%)
Frame = +3
Query: 18 AEMAIANSPAAANPQLQEQLRNSMPQVLQAFERPEVRNALTNPRVLQAIFXXXXXXXXXX 197
A+M + A NPQLQEQLR +P LQ + PE + LTNPR +QA+
Sbjct: 421 AQMMVNVPLFAGNPQLQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQ 480
Query: 198 XEAPHLXXXXXXXXXXXXXXXXXXXXXXXXXGGXXXXXXXXXXXXXXXXXXXXXXXXXXX 377
EAP L
Sbjct: 481 TEAPGLVPSLGSFGISRTPAPSAGSNAGSTPEAPTSSPATPATSSPTGASSAQQQLMQQM 540
Query: 378 XXXNPGAGLNSAVGGNPEQLYSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRIL 551
G+G NS V PE + +LE + MGF NR+ANL+ALI T GD+NAA+ R+L
Sbjct: 541 IQLLAGSG-NSQVQ-TPEVRFQQQLEQLNSMGFINREANLQALIATGGDINAAIERLL 596
>sp|Q99NB8|UBQL4_MOUSE Ubiquilin-4 (Ataxin-1 ubiquitin-like interacting protein A1U)
Length = 596
Score = 72.4 bits (176), Expect = 1e-12
Identities = 56/178 (31%), Positives = 72/178 (40%)
Frame = +3
Query: 18 AEMAIANSPAAANPQLQEQLRNSMPQVLQAFERPEVRNALTNPRVLQAIFXXXXXXXXXX 197
A+M + A NPQLQEQLR +P LQ + PE + LTNPR +QA+
Sbjct: 416 AQMMVNVPLFAGNPQLQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQ 475
Query: 198 XEAPHLXXXXXXXXXXXXXXXXXXXXXXXXXGGXXXXXXXXXXXXXXXXXXXXXXXXXXX 377
EAP L
Sbjct: 476 TEAPGLVPSLGSFGTPRTSVPLAGSNSGSSAEAPTSSPGVPATSPPSAGSNAQQQLMQQM 535
Query: 378 XXXNPGAGLNSAVGGNPEQLYSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRIL 551
G+G NS V PE + +LE + MGF NR+ANL+ALI T GD+NAA+ R+L
Sbjct: 536 IQLLSGSG-NSQV-PMPEVRFQQQLEQLNSMGFINREANLQALIATGGDINAAIERLL 591
>sp|Q9UHD9|UBQL2_HUMAN Ubiquilin-2 (Protein linking IAP with cytoskeleton-2) (PLIC-2)
(hPLIC-2) (Ubiquitin-like product Chap1/Dsk2) (DSK2
homolog) (Chap1)
Length = 624
Score = 56.2 bits (134), Expect = 9e-08
Identities = 28/56 (50%), Positives = 37/56 (66%)
Frame = +3
Query: 396 AGLNSAVGGNPEQLYSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRILQFDP 563
AG N+ NPE + +LE + MGF NR+ANL+ALI T GD+NAA+ R+L P
Sbjct: 568 AGANAPQLPNPEVRFQQQLEQLNAMGFLNREANLQALIATGGDINAAIERLLGSQP 623
Score = 51.6 bits (122), Expect = 2e-06
Identities = 27/67 (40%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Frame = +3
Query: 18 AEMAIANSPA-AANPQLQEQLRNSMPQVLQAFERPEVRNALTNPRVLQAIFXXXXXXXXX 194
A + NSP ANPQLQEQ+R +P LQ + P+ +A++NPR +QA+
Sbjct: 406 AAQMMLNSPLFTANPQLQEQMRPQLPAFLQQMQNPDTLSAMSNPRAMQALMQIQQGLQTL 465
Query: 195 XXEAPHL 215
EAP L
Sbjct: 466 ATEAPGL 472
Score = 30.0 bits (66), Expect = 6.6
Identities = 14/37 (37%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Frame = +3
Query: 51 ANPQLQEQLRNSMPQVLQAFER-PEVRNALTNPRVLQ 158
+NP L QL + PQ+ Q +R PE+ + L NP +++
Sbjct: 196 SNPDLMRQLIMANPQMQQLIQRNPEISHLLNNPDIMR 232
>sp|Q9UMX0|UBQL1_HUMAN Ubiquilin-1 (Protein linking IAP with cytoskeleton-1) (PLIC-1)
(hPLIC-1)
Length = 589
Score = 55.5 bits (132), Expect = 1e-07
Identities = 28/56 (50%), Positives = 39/56 (69%)
Frame = +3
Query: 396 AGLNSAVGGNPEQLYSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRILQFDP 563
AG+N + NPE + +LE ++ MGF NR+ANL+ALI T GD+NAA+ R+L P
Sbjct: 534 AGVNPQLQ-NPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIERLLGSQP 588
Score = 53.9 bits (128), Expect = 4e-07
Identities = 26/66 (39%), Positives = 37/66 (56%)
Frame = +3
Query: 18 AEMAIANSPAAANPQLQEQLRNSMPQVLQAFERPEVRNALTNPRVLQAIFXXXXXXXXXX 197
A+M + N A NPQLQEQ+R +P LQ + P+ +A++NPR +QA+
Sbjct: 415 AQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQNPDTLSAMSNPRAMQALLQIQQGLQTLA 474
Query: 198 XEAPHL 215
EAP L
Sbjct: 475 TEAPGL 480
Score = 30.0 bits (66), Expect = 6.6
Identities = 14/37 (37%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Frame = +3
Query: 51 ANPQLQEQLRNSMPQVLQAFER-PEVRNALTNPRVLQ 158
+NP L QL + PQ+ Q +R PE+ + L NP +++
Sbjct: 200 SNPDLMRQLIMANPQMQQLIQRNPEISHMLNNPDIMR 236
>sp|Q8R317|UBQL1_MOUSE Ubiquilin-1 (Protein linking IAP with cytoskeleton-1) (PLIC-1)
Length = 582
Score = 53.9 bits (128), Expect = 4e-07
Identities = 26/66 (39%), Positives = 37/66 (56%)
Frame = +3
Query: 18 AEMAIANSPAAANPQLQEQLRNSMPQVLQAFERPEVRNALTNPRVLQAIFXXXXXXXXXX 197
A+M + N A NPQLQEQ+R +P LQ + P+ +A++NPR +QA+
Sbjct: 409 AQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQNPDTLSAMSNPRAMQALLQIQQGLQTLA 468
Query: 198 XEAPHL 215
EAP L
Sbjct: 469 TEAPGL 474
Score = 53.5 bits (127), Expect = 6e-07
Identities = 27/56 (48%), Positives = 39/56 (69%)
Frame = +3
Query: 396 AGLNSAVGGNPEQLYSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRILQFDP 563
AG+N + +PE + +LE ++ MGF NR+ANL+ALI T GD+NAA+ R+L P
Sbjct: 527 AGVNPQLQ-SPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIERLLGSQP 581
Score = 30.0 bits (66), Expect = 6.6
Identities = 14/37 (37%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Frame = +3
Query: 51 ANPQLQEQLRNSMPQVLQAFER-PEVRNALTNPRVLQ 158
+NP L QL + PQ+ Q +R PE+ + L NP +++
Sbjct: 191 SNPDLMRQLIMANPQMQQLIQRNPEISHMLNNPDIMR 227
>sp|Q9JJP9|UBQL1_RAT Ubiquilin-1 (Protein linking IAP with cytoskeleton-1) (PLIC-1)
Length = 582
Score = 53.9 bits (128), Expect = 4e-07
Identities = 26/66 (39%), Positives = 37/66 (56%)
Frame = +3
Query: 18 AEMAIANSPAAANPQLQEQLRNSMPQVLQAFERPEVRNALTNPRVLQAIFXXXXXXXXXX 197
A+M + N A NPQLQEQ+R +P LQ + P+ +A++NPR +QA+
Sbjct: 409 AQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQNPDTLSAMSNPRAMQALLQIQQGLQTLA 468
Query: 198 XEAPHL 215
EAP L
Sbjct: 469 TEAPGL 474
Score = 53.5 bits (127), Expect = 6e-07
Identities = 27/56 (48%), Positives = 39/56 (69%)
Frame = +3
Query: 396 AGLNSAVGGNPEQLYSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRILQFDP 563
AG+N + +PE + +LE ++ MGF NR+ANL+ALI T GD+NAA+ R+L P
Sbjct: 527 AGVNPQLQ-SPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIERLLGSQP 581
Score = 30.8 bits (68), Expect = 3.9
Identities = 14/37 (37%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Frame = +3
Query: 51 ANPQLQEQLRNSMPQVLQAFER-PEVRNALTNPRVLQ 158
+NP L QL + PQ+ Q +R PE+ + L NP +++
Sbjct: 191 SNPDLMRQLIMANPQMQQLIQRNPEISHMLNNPNIMR 227
>sp|Q9QZM0|UBQL2_MOUSE Ubiquilin-2 (Protein linking IAP with cytoskeleton-2) (PLIC-2)
(Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog)
(Chap1)
Length = 638
Score = 53.5 bits (127), Expect = 6e-07
Identities = 25/47 (53%), Positives = 33/47 (70%)
Frame = +3
Query: 423 NPEQLYSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRILQFDP 563
NPE + +LE + MGF NR+ANL+ALI T GD+NAA+ R+L P
Sbjct: 591 NPEVRFQQQLEQLNAMGFLNREANLQALIATGGDINAAIERLLGSQP 637
Score = 51.2 bits (121), Expect = 3e-06
Identities = 25/66 (37%), Positives = 37/66 (56%)
Frame = +3
Query: 18 AEMAIANSPAAANPQLQEQLRNSMPQVLQAFERPEVRNALTNPRVLQAIFXXXXXXXXXX 197
A+M +++ +NPQLQEQ+R +P LQ + PE A++NPR +QA+
Sbjct: 421 AQMMLSSPLFTSNPQLQEQMRPQLPNFLQQMQNPETIAAMSNPRAMQALMQIQQGLQTLA 480
Query: 198 XEAPHL 215
EAP L
Sbjct: 481 TEAPGL 486
Score = 30.0 bits (66), Expect = 6.6
Identities = 14/37 (37%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Frame = +3
Query: 51 ANPQLQEQLRNSMPQVLQAFER-PEVRNALTNPRVLQ 158
+NP L QL + PQ+ Q +R PE+ + L NP +++
Sbjct: 207 SNPDLMRQLIMANPQMQQLIQRNPEISHLLNNPDIMR 243
>sp|Q9H347|UBQL3_HUMAN Ubiquilin-3
Length = 655
Score = 49.3 bits (116), Expect = 1e-05
Identities = 27/56 (48%), Positives = 36/56 (64%), Gaps = 5/56 (8%)
Frame = +3
Query: 402 LNSAVGGNPEQL-----YSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRILQ 554
L V NP+QL + +LE + MGF NR+ANL+ALI T GDV+AAV ++ Q
Sbjct: 599 LQDLVSTNPQQLQPEAHFQVQLEQLRSMGFLNREANLQALIATGGDVDAAVEKLRQ 654
>sp|Q8C5U9|UBQL3_MOUSE Ubiquilin-3
Length = 658
Score = 43.5 bits (101), Expect = 6e-04
Identities = 24/54 (44%), Positives = 34/54 (62%), Gaps = 5/54 (9%)
Frame = +3
Query: 402 LNSAVGGNPEQL-----YSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRI 548
L + NP+QL + +LE + MGF N +ANL+ALI T GDV+AAV ++
Sbjct: 602 LQALASTNPQQLQLEAHFRVQLEQLRAMGFLNLEANLQALIATEGDVDAAVEKL 655
Score = 30.0 bits (66), Expect = 6.6
Identities = 15/53 (28%), Positives = 26/53 (49%)
Frame = +3
Query: 57 PQLQEQLRNSMPQVLQAFERPEVRNALTNPRVLQAIFXXXXXXXXXXXEAPHL 215
P++Q ++ +P +L ++ A+ NPRV+QA+ EAP L
Sbjct: 498 PRIQNEIHQQLPLLLH------LQTAMANPRVMQALLQIEQGLQILATEAPRL 544
>sp|O74345|UCP3_SCHPO UBA-domain containing protein 3
Length = 601
Score = 36.6 bits (83), Expect = 0.070
Identities = 17/39 (43%), Positives = 23/39 (58%)
Frame = +3
Query: 438 YSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRILQ 554
Y+ L T+ MGF + N AL ET GDV A+ +I+Q
Sbjct: 158 YADSLSTLHDMGFSDDSVNTHALEETNGDVTRAIEKIVQ 196
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,296,263
Number of Sequences: 369166
Number of extensions: 1327130
Number of successful extensions: 2829
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2745
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2829
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6510836890
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)