Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_H15
(183 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9UBU6|FA8A1_HUMAN Protein FAM8A1 (Autosomal highly cons... 34 0.090
sp|Q04721|NOTC2_HUMAN Neurogenic locus notch homolog protei... 31 0.76
sp|P18168|SERR_DROME Serrate protein precursor (Beaded prot... 29 3.8
sp|Q01705|NOTC1_MOUSE Neurogenic locus notch homolog protei... 28 5.0
sp|P46531|NOTC1_HUMAN Neurogenic locus notch homolog protei... 28 5.0
sp|Q9QW30|NOTC2_RAT Neurogenic locus notch homolog protein ... 28 6.5
sp|Q9QYE5|JAG2_MOUSE Jagged-2 precursor (Jagged2) 28 6.5
sp|O35516|NOTC2_MOUSE Neurogenic locus notch homolog protei... 28 6.5
sp|Q9Y219|JAG2_HUMAN Jagged-2 precursor (Jagged2) (HJ2) 28 6.5
>sp|Q9UBU6|FA8A1_HUMAN Protein FAM8A1 (Autosomal highly conserved protein)
Length = 413
Score = 34.3 bits (77), Expect = 0.090
Identities = 13/20 (65%), Positives = 17/20 (85%)
Frame = +1
Query: 4 LIFNHHRTTYDLIAGTLVVK 63
L F H+RT YD++AGT+VVK
Sbjct: 389 LFFQHNRTAYDIVAGTIVVK 408
>sp|Q04721|NOTC2_HUMAN Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2)
[Contains: Notch 2 extracellular truncation; Notch 2
intracellular domain]
Length = 2471
Score = 31.2 bits (69), Expect = 0.76
Identities = 15/32 (46%), Positives = 18/32 (56%), Gaps = 4/32 (12%)
Frame = -2
Query: 146 TCYCPGGWFG----LRTAHPA*LSRRCLGGGT 63
TC C G+ G T+HP +SR CL GGT
Sbjct: 89 TCRCASGFTGEDCQYSTSHPCFVSRPCLNGGT 120
>sp|P18168|SERR_DROME Serrate protein precursor (Beaded protein)
Length = 1404
Score = 28.9 bits (63), Expect = 3.8
Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 2/40 (5%)
Frame = -2
Query: 158 DRNFTCYCPGGWFGLRTAHPA--*LSRRCLGGGTFTTKVP 45
D +FTC C GW G R + A + +C GGT P
Sbjct: 814 DGDFTCECMSGWTGKRCSERATGCYAGQCQNGGTCMPGAP 853
>sp|Q01705|NOTC1_MOUSE Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch
A) (mT14) (p300) [Contains: Notch 1 extracellular
truncation; Notch 1 intracellular domain]
Length = 2531
Score = 28.5 bits (62), Expect = 5.0
Identities = 15/33 (45%), Positives = 17/33 (51%), Gaps = 2/33 (6%)
Frame = -2
Query: 155 RNFTCYCPGGWFGLRTAHPA*L--SRRCLGGGT 63
R F C CP G+ G + A S RCL GGT
Sbjct: 1330 RGFICRCPAGFEGATCENDARTCGSLRCLNGGT 1362
>sp|P46531|NOTC1_HUMAN Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1)
(Translocation-associated notch protein TAN-1) [Contains:
Notch 1 extracellular truncation; Notch 1 intracellular
domain]
Length = 2556
Score = 28.5 bits (62), Expect = 5.0
Identities = 15/33 (45%), Positives = 17/33 (51%), Gaps = 2/33 (6%)
Frame = -2
Query: 155 RNFTCYCPGGWFGLRTAHPA*L--SRRCLGGGT 63
R F C CP G+ G + A S RCL GGT
Sbjct: 1331 RGFICKCPAGFEGATCENDARTCGSLRCLNGGT 1363
>sp|Q9QW30|NOTC2_RAT Neurogenic locus notch homolog protein 2 precursor (Notch 2)
[Contains: Notch 2 extracellular truncation; Notch 2
intracellular domain]
Length = 2471
Score = 28.1 bits (61), Expect = 6.5
Identities = 14/32 (43%), Positives = 17/32 (53%), Gaps = 4/32 (12%)
Frame = -2
Query: 146 TCYCPGGWFG----LRTAHPA*LSRRCLGGGT 63
TC C G+ G T+HP +SR C GGT
Sbjct: 89 TCRCAPGFTGEDCQYSTSHPCFVSRPCQNGGT 120
>sp|Q9QYE5|JAG2_MOUSE Jagged-2 precursor (Jagged2)
Length = 1247
Score = 28.1 bits (61), Expect = 6.5
Identities = 14/41 (34%), Positives = 18/41 (43%), Gaps = 2/41 (4%)
Frame = -2
Query: 164 QIDRNFTCYCPGGWFGLRTA--HPA*LSRRCLGGGTFTTKV 48
++ F C+CP GW G A S C GGT +V
Sbjct: 364 EVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQV 404
>sp|O35516|NOTC2_MOUSE Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch
B) [Contains: Notch 2 extracellular truncation; Notch 2
intracellular domain]
Length = 2470
Score = 28.1 bits (61), Expect = 6.5
Identities = 14/32 (43%), Positives = 17/32 (53%), Gaps = 4/32 (12%)
Frame = -2
Query: 146 TCYCPGGWFG----LRTAHPA*LSRRCLGGGT 63
TC C G+ G T+HP +SR C GGT
Sbjct: 89 TCRCAPGFTGEDCQYSTSHPCFVSRPCQNGGT 120
>sp|Q9Y219|JAG2_HUMAN Jagged-2 precursor (Jagged2) (HJ2)
Length = 1238
Score = 28.1 bits (61), Expect = 6.5
Identities = 14/41 (34%), Positives = 18/41 (43%), Gaps = 2/41 (4%)
Frame = -2
Query: 164 QIDRNFTCYCPGGWFGLRTA--HPA*LSRRCLGGGTFTTKV 48
++ F C+CP GW G A S C GGT +V
Sbjct: 364 EVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQV 404
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,241,478
Number of Sequences: 369166
Number of extensions: 378508
Number of successful extensions: 2244
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 2056
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2244
length of database: 68,354,980
effective HSP length: 33
effective length of database: 62,258,725
effective search space used: 1680985575
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)