Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_H07
(818 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P13230|GRP33_ARTSA Glycine-rich protein GRP33 94 6e-19
sp|Q60749|SAM68_MOUSE KH domain containing, RNA binding, si... 81 3e-15
sp|Q07666|SAM68_HUMAN KH domain containing, RNA binding, si... 81 3e-15
sp|Q91V33|SAM68_RAT KH domain containing, RNA binding, sign... 81 3e-15
sp|Q8UUW7|SAM68_CHICK KH domain containing, RNA binding, si... 81 3e-15
sp|O01367|HOW_DROME Held out wings protein (KH-domain prote... 52 2e-06
sp|Q17339|GLD1_CAEEL Female germline-specific tumor suppres... 48 4e-05
sp|Q10900|CTPI_MYCTU Probable cation-transporting ATPase I 37 0.050
sp|Q8NHZ7|MB3L2_HUMAN Methyl-CpG binding domain protein 3-l... 33 1.2
sp|Q86VP6|CAND1_HUMAN Cullin-associated NEDD8-dissociated p... 30 6.1
>sp|P13230|GRP33_ARTSA Glycine-rich protein GRP33
Length = 308
Score = 93.6 bits (231), Expect = 6e-19
Identities = 49/102 (48%), Positives = 69/102 (67%), Gaps = 7/102 (6%)
Frame = +2
Query: 47 KTVQEQTNTKMSILGAGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNI 226
K +Q++T TK+SILG GS+R+ KE+EL NSGD KY HL ++LH++I SI +P+EA+ +
Sbjct: 103 KQLQDETMTKISILGRGSMRDRNKEEELRNSGDVKYAHLNEQLHIEIISIASPAEAHARM 162
Query: 227 SYALAEVKKVMIP--DPN-----EQAPGQMPMVTPLMGGPNP 331
+YAL E+KK + P DPN G M + +MGGP P
Sbjct: 163 AYALTEIKKYITPEEDPNYMMMAGHGAGPMMGMGGMMGGPGP 204
>sp|Q60749|SAM68_MOUSE KH domain containing, RNA binding, signal transduction associated
protein 1 (p21 Ras GTPase-activating protein-associated
p62) (GAP-associated tyrosine phosphoprotein p62)
(Src-associated in mitosis 68 kDa protein) (Sam68) (p68)
Length = 443
Score = 81.3 bits (199), Expect = 3e-15
Identities = 43/99 (43%), Positives = 62/99 (62%), Gaps = 1/99 (1%)
Frame = +2
Query: 47 KTVQEQTNTKMSILGAGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNI 226
K +QE+T K+S+LG GS+R+ KE+EL GDPKY HL LH+ I+ G P EAY +
Sbjct: 185 KRLQEETGAKISVLGKGSMRDKAKEEELRKGGDPKYAHLNMDLHVFIEVFGPPCEAYALM 244
Query: 227 SYALAEVKKVMIPD-PNEQAPGQMPMVTPLMGGPNPGFG 340
++A+ EVKK ++PD ++ Q ++ L G P P G
Sbjct: 245 AHAMEEVKKFLVPDMMDDICQEQFLELSYLNGVPEPSRG 283
>sp|Q07666|SAM68_HUMAN KH domain containing, RNA binding, signal transduction associated
protein 1 (p21 Ras GTPase-activating protein-associated
p62) (GAP-associated tyrosine phosphoprotein p62)
(Src-associated in mitosis 68 kDa protein) (Sam68) (p68)
Length = 443
Score = 81.3 bits (199), Expect = 3e-15
Identities = 43/99 (43%), Positives = 62/99 (62%), Gaps = 1/99 (1%)
Frame = +2
Query: 47 KTVQEQTNTKMSILGAGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNI 226
K +QE+T K+S+LG GS+R+ KE+EL GDPKY HL LH+ I+ G P EAY +
Sbjct: 185 KRLQEETGAKISVLGKGSMRDKAKEEELRKGGDPKYAHLNMDLHVFIEVFGPPCEAYALM 244
Query: 227 SYALAEVKKVMIPD-PNEQAPGQMPMVTPLMGGPNPGFG 340
++A+ EVKK ++PD ++ Q ++ L G P P G
Sbjct: 245 AHAMEEVKKFLVPDMMDDICQEQFLELSYLNGVPEPSRG 283
>sp|Q91V33|SAM68_RAT KH domain containing, RNA binding, signal transduction associated
protein 1 (p21 Ras GTPase-activating protein-associated
p62) (GAP-associated tyrosine phosphoprotein p62)
(Src-associated in mitosis 68 kDa protein) (Sam68) (p68)
Length = 443
Score = 81.3 bits (199), Expect = 3e-15
Identities = 43/99 (43%), Positives = 62/99 (62%), Gaps = 1/99 (1%)
Frame = +2
Query: 47 KTVQEQTNTKMSILGAGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNI 226
K +QE+T K+S+LG GS+R+ KE+EL GDPKY HL LH+ I+ G P EAY +
Sbjct: 185 KRLQEETGAKISVLGKGSMRDKAKEEELRKGGDPKYAHLNMDLHVFIEVFGPPCEAYALM 244
Query: 227 SYALAEVKKVMIPD-PNEQAPGQMPMVTPLMGGPNPGFG 340
++A+ EVKK ++PD ++ Q ++ L G P P G
Sbjct: 245 AHAMEEVKKFLVPDMMDDICQEQFLELSYLNGVPEPSRG 283
>sp|Q8UUW7|SAM68_CHICK KH domain containing, RNA binding, signal transduction associated
protein 1 (Src-associated in mitosis 68 kDa protein)
(Sam68)
Length = 433
Score = 81.3 bits (199), Expect = 3e-15
Identities = 46/114 (40%), Positives = 64/114 (56%), Gaps = 10/114 (8%)
Frame = +2
Query: 47 KTVQEQTNTKMSILGAGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNI 226
K +QE+T K+S+LG GS+R+ KE+EL GDPKY HL LH+ I+ G P EAY +
Sbjct: 168 KRLQEETGAKISVLGKGSMRDKAKEEELRKGGDPKYAHLNMDLHVFIEVFGPPCEAYALM 227
Query: 227 SYALAEVKKVMIPDPNEQAPGQ----------MPMVTPLMGGPNPGFGAMRTQP 358
++A+ EVKK ++PD + + +P T GGP G GA P
Sbjct: 228 AHAMEEVKKFLVPDMMDDICQEQFLELSYLNGVPEPTRGRGGPVRGRGAAPPPP 281
>sp|O01367|HOW_DROME Held out wings protein (KH-domain protein KH93F) (Putative
RNA-binding protein) (Muscle-specific protein) (Wings
held out protein) (Struthio protein) (Quaking-related
93F)
Length = 405
Score = 52.0 bits (123), Expect = 2e-06
Identities = 28/82 (34%), Positives = 48/82 (58%)
Frame = +2
Query: 47 KTVQEQTNTKMSILGAGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNI 226
K ++++T K+ + G GS+R+ +KE N G P + HL D LH+ I + A +
Sbjct: 166 KQLEQETGCKIMVRGKGSMRDKKKEDA--NRGKPNWEHLSDDLHVLITVEDTENRATVKL 223
Query: 227 SYALAEVKKVMIPDPNEQAPGQ 292
+ A+AEV+K+++P QA G+
Sbjct: 224 AQAVAEVQKLLVP----QAEGE 241
>sp|Q17339|GLD1_CAEEL Female germline-specific tumor suppressor gld-1 (Defective in germ
line development protein 1)
Length = 463
Score = 47.8 bits (112), Expect = 4e-05
Identities = 23/75 (30%), Positives = 41/75 (54%)
Frame = +2
Query: 47 KTVQEQTNTKMSILGAGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNI 226
K +++ T K+ + G GS+R +K +E + G + HL D LH+ + + + +
Sbjct: 234 KQLEQDTGCKIMVRGKGSMR--DKSKESAHRGKANWEHLEDDLHVLVQCEDTENRVHIKL 291
Query: 227 SYALAEVKKVMIPDP 271
AL +VKK++IP P
Sbjct: 292 QAALEQVKKLLIPAP 306
>sp|Q10900|CTPI_MYCTU Probable cation-transporting ATPase I
Length = 1625
Score = 37.4 bits (85), Expect = 0.050
Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 9/93 (9%)
Frame = +2
Query: 68 NTKMSILGAGSLRNPEKEQELLNSGDPKYNHLRDRLHLQIDSIGNPSEAYYNISYALAEV 247
NT +L G+LR ++ + ++ G R LH Q D G + Y ++ AL
Sbjct: 403 NTGQLVLDPGALRRLDRVRVVVIDGAALRGDNRAVLHAQGDEPGWDDDRVYEVADALLHG 462
Query: 248 KKVMIPDPNE---------QAPGQMPMVTPLMG 319
++ PDP+E AP Q P TP G
Sbjct: 463 EQAPEPDPDELPATGARLRWAPAQGPSATPAQG 495
>sp|Q8NHZ7|MB3L2_HUMAN Methyl-CpG binding domain protein 3-like 2 (MBD3-like 2)
Length = 204
Score = 32.7 bits (73), Expect = 1.2
Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 1/67 (1%)
Frame = +2
Query: 173 LHLQ-IDSIGNPSEAYYNISYALAEVKKVMIPDPNEQAPGQMPMVTPLMGGPNPGFGAMR 349
LHL+ + SI P A ++ A AE + P E PG+ P V GGP PG G
Sbjct: 109 LHLESVLSILAPGTASESLDRAGAE----RVRSPLEPTPGRFPAVA---GGPTPGMGCQL 161
Query: 350 TQPMTQQ 370
P++ Q
Sbjct: 162 PPPLSGQ 168
>sp|Q86VP6|CAND1_HUMAN Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and
neddylation-dissociated protein 1) (p120 CAND1)
(TBP-interacting protein TIP120A) (TBP-interacting
protein of 120 kDa A)
Length = 1230
Score = 30.4 bits (67), Expect = 6.1
Identities = 16/36 (44%), Positives = 21/36 (58%), Gaps = 1/36 (2%)
Frame = +2
Query: 11 LENCWDLLEKHCKTVQEQT-NTKMSILGAGSLRNPE 115
+EN W LL KHC+ +E T N LG +L +PE
Sbjct: 929 VENIWALLLKHCECAEEGTRNVVAECLGKLTLIDPE 964
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,743,674
Number of Sequences: 369166
Number of extensions: 1745108
Number of successful extensions: 4273
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4127
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4268
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7859674995
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)