Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_005_H06 (482 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q08094|CNN2_PIG Calponin-2 (Calponin H2, smooth muscle) ... 52 7e-07 sp|Q99439|CNN2_HUMAN Calponin-2 (Calponin H2, smooth muscle... 52 7e-07 sp|P37397|CNN3_RAT Calponin-3 (Calponin, acidic isoform) (C... 52 7e-07 sp|Q15417|CNN3_HUMAN Calponin-3 (Calponin, acidic isoform) 52 9e-07 sp|Q9DAW9|CNN3_MOUSE Calponin-3 (Calponin, acidic isoform) 52 9e-07 sp|Q08093|CNN2_MOUSE Calponin-2 (Calponin H2, smooth muscle... 51 2e-06 sp|P26932|CNN1_CHICK Calponin-1 (Calponin, smooth muscle) 48 1e-05 sp|Q08290|CNN1_RAT Calponin-1 (Calponin H1, smooth muscle) ... 42 7e-04 sp|Q08092|CNN1_PIG Calponin-1 (Calponin H1, smooth muscle) ... 42 7e-04 sp|P51911|CNN1_HUMAN Calponin-1 (Calponin H1, smooth muscle... 42 7e-04
>sp|Q08094|CNN2_PIG Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin) Length = 296 Score = 52.0 bits (123), Expect = 7e-07 Identities = 37/71 (52%), Positives = 42/71 (59%), Gaps = 1/71 (1%) Frame = +2 Query: 26 SIISLQYGTNLGANQNGMRI-GTQRHITDISCGLEPNKNSSNFISLQMGPSMKEVANQSG 202 S ISLQ GTN A+Q GM GT+RHI D G + NSS +SLQMG + ANQSG Sbjct: 204 STISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKCDNSS--MSLQMG--YTQGANQSG 259 Query: 203 MSFGAQRHIND 235 FG R I D Sbjct: 260 QVFGLGRQIYD 270
Score = 47.4 bits (111), Expect = 2e-05 Identities = 34/77 (44%), Positives = 47/77 (61%), Gaps = 2/77 (2%) Frame = +2 Query: 14 KEAQSIISLQYGTNLGANQNGM-RIGTQRHITDISCGLEPNKNSSNFISLQMGPSMKEVA 190 K Q +I LQ GTN A+Q+GM GT+RH+ D + P + S ISLQMG + + A Sbjct: 160 KAGQCVIGLQMGTNKCASQSGMTAYGTRRHLYDPKNHILPPMDHST-ISLQMGTN--KCA 216 Query: 191 NQSGMSF-GAQRHINDS 238 +Q GM+ G +RHI D+ Sbjct: 217 SQVGMTAPGTRRHIYDT 233
>sp|Q99439|CNN2_HUMAN Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin) Length = 309 Score = 52.0 bits (123), Expect = 7e-07 Identities = 37/71 (52%), Positives = 42/71 (59%), Gaps = 1/71 (1%) Frame = +2 Query: 26 SIISLQYGTNLGANQNGMRI-GTQRHITDISCGLEPNKNSSNFISLQMGPSMKEVANQSG 202 S ISLQ GTN A+Q GM GT+RHI D G + NSS +SLQMG + ANQSG Sbjct: 204 STISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKCDNSS--MSLQMG--YTQGANQSG 259 Query: 203 MSFGAQRHIND 235 FG R I D Sbjct: 260 QVFGLGRQIYD 270
Score = 47.4 bits (111), Expect = 2e-05 Identities = 34/77 (44%), Positives = 47/77 (61%), Gaps = 2/77 (2%) Frame = +2 Query: 14 KEAQSIISLQYGTNLGANQNGM-RIGTQRHITDISCGLEPNKNSSNFISLQMGPSMKEVA 190 K Q +I LQ GTN A+Q+GM GT+RH+ D + P + S ISLQMG + + A Sbjct: 160 KAGQCVIGLQMGTNKCASQSGMTAYGTRRHLYDPKNHILPPMDHST-ISLQMGTN--KCA 216 Query: 191 NQSGMSF-GAQRHINDS 238 +Q GM+ G +RHI D+ Sbjct: 217 SQVGMTAPGTRRHIYDT 233
>sp|P37397|CNN3_RAT Calponin-3 (Calponin, acidic isoform) (Calponin, non-muscle isoform) Length = 330 Score = 52.0 bits (123), Expect = 7e-07 Identities = 37/73 (50%), Positives = 47/73 (64%), Gaps = 2/73 (2%) Frame = +2 Query: 23 QSIISLQYGTNLGANQNGMRI-GTQRHITDISCGLEPNKNSSNFISLQMGPSMKEVANQS 199 Q+ ISLQ GTN GA+Q GM GT+R I D L+P NS+ ISLQMG + +VA+Q Sbjct: 201 QTTISLQMGTNKGASQAGMSAPGTRRDIYDQKLTLQPVDNST--ISLQMGTN--KVASQK 256 Query: 200 GMS-FGAQRHIND 235 GMS +G R + D Sbjct: 257 GMSVYGLGRQVYD 269
Score = 42.7 bits (99), Expect = 4e-04 Identities = 33/76 (43%), Positives = 45/76 (59%), Gaps = 2/76 (2%) Frame = +2 Query: 14 KEAQSIISLQYGTNLGANQNGM-RIGTQRHITDISCGLEPNKNSSNFISLQMGPSMKEVA 190 K QS+I LQ GTN A+Q GM GT+RH+ D + + + ISLQMG + + A Sbjct: 158 KAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQTT-ISLQMGTN--KGA 214 Query: 191 NQSGMSF-GAQRHIND 235 +Q+GMS G +R I D Sbjct: 215 SQAGMSAPGTRRDIYD 230
>sp|Q15417|CNN3_HUMAN Calponin-3 (Calponin, acidic isoform) Length = 329 Score = 51.6 bits (122), Expect = 9e-07 Identities = 37/73 (50%), Positives = 47/73 (64%), Gaps = 2/73 (2%) Frame = +2 Query: 23 QSIISLQYGTNLGANQNGMRI-GTQRHITDISCGLEPNKNSSNFISLQMGPSMKEVANQS 199 Q+ ISLQ GTN GA+Q GM GT+R I D L+P NS+ ISLQMG + +VA+Q Sbjct: 201 QTTISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVDNST--ISLQMGTN--KVASQK 256 Query: 200 GMS-FGAQRHIND 235 GMS +G R + D Sbjct: 257 GMSVYGLGRQVYD 269
Score = 40.8 bits (94), Expect = 0.002 Identities = 32/76 (42%), Positives = 45/76 (59%), Gaps = 2/76 (2%) Frame = +2 Query: 14 KEAQSIISLQYGTNLGANQNGM-RIGTQRHITDISCGLEPNKNSSNFISLQMGPSMKEVA 190 K QS+I LQ GTN A+Q GM GT+RH+ D + + + ISLQMG + + A Sbjct: 158 KAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQTT-ISLQMGTN--KGA 214 Query: 191 NQSGM-SFGAQRHIND 235 +Q+GM + G +R I D Sbjct: 215 SQAGMLAPGTRRDIYD 230
>sp|Q9DAW9|CNN3_MOUSE Calponin-3 (Calponin, acidic isoform) Length = 330 Score = 51.6 bits (122), Expect = 9e-07 Identities = 37/73 (50%), Positives = 47/73 (64%), Gaps = 2/73 (2%) Frame = +2 Query: 23 QSIISLQYGTNLGANQNGMRI-GTQRHITDISCGLEPNKNSSNFISLQMGPSMKEVANQS 199 Q+ ISLQ GTN GA+Q GM GT+R I D L+P NS+ ISLQMG + +VA+Q Sbjct: 201 QTTISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVDNST--ISLQMGTN--KVASQK 256 Query: 200 GMS-FGAQRHIND 235 GMS +G R + D Sbjct: 257 GMSVYGLGRQVYD 269
Score = 40.8 bits (94), Expect = 0.002 Identities = 32/76 (42%), Positives = 45/76 (59%), Gaps = 2/76 (2%) Frame = +2 Query: 14 KEAQSIISLQYGTNLGANQNGM-RIGTQRHITDISCGLEPNKNSSNFISLQMGPSMKEVA 190 K QS+I LQ GTN A+Q GM GT+RH+ D + + + ISLQMG + + A Sbjct: 158 KAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQTT-ISLQMGTN--KGA 214 Query: 191 NQSGM-SFGAQRHIND 235 +Q+GM + G +R I D Sbjct: 215 SQAGMLAPGTRRDIYD 230
>sp|Q08093|CNN2_MOUSE Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin) Length = 305 Score = 50.8 bits (120), Expect = 2e-06 Identities = 36/69 (52%), Positives = 41/69 (59%), Gaps = 1/69 (1%) Frame = +2 Query: 32 ISLQYGTNLGANQNGMRI-GTQRHITDISCGLEPNKNSSNFISLQMGPSMKEVANQSGMS 208 ISLQ GTN A+Q GM GT+RHI D G + NSS +SLQMG + ANQSG Sbjct: 206 ISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKCDNSS--MSLQMG--YTQGANQSGQV 261 Query: 209 FGAQRHIND 235 FG R I D Sbjct: 262 FGLGRQIYD 270
Score = 45.4 bits (106), Expect = 7e-05 Identities = 33/77 (42%), Positives = 46/77 (59%), Gaps = 2/77 (2%) Frame = +2 Query: 14 KEAQSIISLQYGTNLGANQNGM-RIGTQRHITDISCGLEPNKNSSNFISLQMGPSMKEVA 190 K Q +I LQ GTN A+Q+GM GT+RH+ D + P + ISLQMG + + A Sbjct: 160 KAGQCVIGLQMGTNKCASQSGMTAYGTRRHLYDPKNHILPPMDHCT-ISLQMGTN--KCA 216 Query: 191 NQSGMSF-GAQRHINDS 238 +Q GM+ G +RHI D+ Sbjct: 217 SQVGMTAPGTRRHIYDT 233
>sp|P26932|CNN1_CHICK Calponin-1 (Calponin, smooth muscle) Length = 292 Score = 47.8 bits (112), Expect = 1e-05 Identities = 33/73 (45%), Positives = 46/73 (63%), Gaps = 2/73 (2%) Frame = +2 Query: 23 QSIISLQYGTNLGANQNGMRI-GTQRHITDISCGLEPNKNSSNFISLQMGPSMKEVANQS 199 Q+ ISLQ GTN GA+Q GM GT+R I + S G+E + +N I LQMG + + A+Q Sbjct: 201 QATISLQMGTNKGASQAGMTAPGTKRQIFEPSLGME--RCDTNIIGLQMGSN--KGASQQ 256 Query: 200 GMS-FGAQRHIND 235 GM+ +G R + D Sbjct: 257 GMTVYGLPRQVYD 269
>sp|Q08290|CNN1_RAT Calponin-1 (Calponin H1, smooth muscle) (Basic calponin) Length = 297 Score = 42.0 bits (97), Expect = 7e-04 Identities = 31/73 (42%), Positives = 44/73 (60%), Gaps = 2/73 (2%) Frame = +2 Query: 23 QSIISLQYGTNLGANQNGMRI-GTQRHITDISCGLEPNKNSSNFISLQMGPSMKEVANQS 199 Q+ ISLQ GTN GA+Q GM GT+R I + G+E + +SLQMG + + A+Q Sbjct: 201 QATISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLN--VSLQMGSN--KGASQR 256 Query: 200 GMS-FGAQRHIND 235 GM+ +G R + D Sbjct: 257 GMTVYGLPRQVYD 269
>sp|Q08092|CNN1_PIG Calponin-1 (Calponin H1, smooth muscle) (Basic calponin) Length = 297 Score = 42.0 bits (97), Expect = 7e-04 Identities = 31/73 (42%), Positives = 44/73 (60%), Gaps = 2/73 (2%) Frame = +2 Query: 23 QSIISLQYGTNLGANQNGMRI-GTQRHITDISCGLEPNKNSSNFISLQMGPSMKEVANQS 199 Q+ ISLQ GTN GA+Q GM GT+R I + G+E + +SLQMG + + A+Q Sbjct: 201 QATISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLN--VSLQMGSN--KGASQR 256 Query: 200 GMS-FGAQRHIND 235 GM+ +G R + D Sbjct: 257 GMTVYGLPRQVYD 269
>sp|P51911|CNN1_HUMAN Calponin-1 (Calponin H1, smooth muscle) (Basic calponin) Length = 297 Score = 42.0 bits (97), Expect = 7e-04 Identities = 31/73 (42%), Positives = 44/73 (60%), Gaps = 2/73 (2%) Frame = +2 Query: 23 QSIISLQYGTNLGANQNGMRI-GTQRHITDISCGLEPNKNSSNFISLQMGPSMKEVANQS 199 Q+ ISLQ GTN GA+Q GM GT+R I + G+E + +SLQMG + + A+Q Sbjct: 201 QATISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLN--VSLQMGSN--KGASQR 256 Query: 200 GMS-FGAQRHIND 235 GM+ +G R + D Sbjct: 257 GMTVYGLPRQVYD 269
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 56,985,853 Number of Sequences: 369166 Number of extensions: 1111822 Number of successful extensions: 2246 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2193 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2236 length of database: 68,354,980 effective HSP length: 102 effective length of database: 49,512,010 effective search space used: 2871696580 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)