Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_G22
(831 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8VDD5|MYH9_MOUSE Myosin-9 (Myosin heavy chain, nonmuscl... 102 1e-21
sp|P35579|MYH9_HUMAN Myosin-9 (Myosin heavy chain, nonmuscl... 102 2e-21
sp|Q62812|MYH9_RAT Myosin-9 (Myosin heavy chain, nonmuscle ... 101 3e-21
sp|P14105|MYH9_CHICK Myosin-9 (Myosin heavy chain, nonmuscl... 100 5e-21
sp|P35749|MYH11_HUMAN Myosin-11 (Myosin heavy chain, smooth... 99 1e-20
sp|Q61879|MYH10_MOUSE Myosin-10 (Myosin heavy chain, nonmus... 98 3e-20
sp|Q9JLT0|MYH10_RAT Myosin-10 (Myosin heavy chain, nonmuscl... 98 3e-20
sp|Q27991|MYH10_BOVIN Myosin-10 (Myosin heavy chain, nonmus... 98 3e-20
sp|P35748|MYH11_RABIT Myosin-11 (Myosin heavy chain, smooth... 97 7e-20
sp|O08638|MYH11_MOUSE Myosin-11 (Myosin heavy chain, smooth... 96 9e-20
>sp|Q8VDD5|MYH9_MOUSE Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy
chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin
heavy chain, type A) (Nonmuscle myosin heavy chain-A)
(NMMHC-A)
Length = 1960
Score = 102 bits (254), Expect = 1e-21
Identities = 59/210 (28%), Positives = 104/210 (49%)
Frame = +2
Query: 11 EEIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELN 190
+EIA + A+ +K+R+E+ ++ L + D+ KK Q++Q+ +LN
Sbjct: 1708 DEIANSSGKGALALEEKRRLEARIALLEEELEEEQGNTELINDRLKKANLQIDQINTDLN 1767
Query: 191 VERQNATRLENQKSTAERLNXXXXXXXXXXXXXTGKKYKATVSAQQIKIQSLDAQLDAKI 370
+ER +A + EN + ER N KYKA+++A + KI L+ QLD +
Sbjct: 1768 LERSHAQKNENARQQLERQNKELKAKLQEMESAVKSKYKASIAALEAKIAQLEEQLDNET 1827
Query: 371 EEINQAXXXXXXXXXXXXXIMALMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNA 550
+E A ++ + DE+R A+ +Q +KA+ R K+ +R L+ +E
Sbjct: 1828 KERQAASKQVRRTEKKLKDVLLQVEDERRNAEQFKDQADKASTRLKQLKRQLEEAEEEAQ 1887
Query: 551 ALTTQNRRLQRDLEEVNETKEARDQEIKVL 640
R+LQR+LE+ ET +A ++E+ L
Sbjct: 1888 RANASRRKLQRELEDATETADAMNREVSSL 1917
>sp|P35579|MYH9_HUMAN Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy
chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin
heavy chain, type A) (Nonmuscle myosin heavy chain-A)
(NMMHC-A)
Length = 1960
Score = 102 bits (253), Expect = 2e-21
Identities = 59/210 (28%), Positives = 104/210 (49%)
Frame = +2
Query: 11 EEIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELN 190
+EIA + A+ +K+R+E+ ++ L + D+ KK Q++Q+ +LN
Sbjct: 1708 DEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLN 1767
Query: 191 VERQNATRLENQKSTAERLNXXXXXXXXXXXXXTGKKYKATVSAQQIKIQSLDAQLDAKI 370
+ER +A + EN + ER N KYKA+++A + KI L+ QLD +
Sbjct: 1768 LERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNET 1827
Query: 371 EEINQAXXXXXXXXXXXXXIMALMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNA 550
+E A ++ + DE+R A+ +Q +KA+ R K+ +R L+ +E
Sbjct: 1828 KERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQ 1887
Query: 551 ALTTQNRRLQRDLEEVNETKEARDQEIKVL 640
R+LQR+LE+ ET +A ++E+ L
Sbjct: 1888 RANASRRKLQRELEDATETADAMNREVSSL 1917
>sp|Q62812|MYH9_RAT Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy
chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin
heavy chain, type A) (Nonmuscle myosin heavy chain-A)
(NMMHC-A)
Length = 1961
Score = 101 bits (251), Expect = 3e-21
Identities = 59/210 (28%), Positives = 104/210 (49%)
Frame = +2
Query: 11 EEIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELN 190
+EIA + A+ +K+R+E+ ++ L + D+ KK Q++Q+ +LN
Sbjct: 1709 DEIANSSGKGALALEEKRRLEALIALLEEELEEEQGNTELINDRLKKANLQIDQINTDLN 1768
Query: 191 VERQNATRLENQKSTAERLNXXXXXXXXXXXXXTGKKYKATVSAQQIKIQSLDAQLDAKI 370
+ER +A + EN + ER N KYKA+++A + KI L+ QLD +
Sbjct: 1769 LERSHAQKNENARQQLERQNKELKAKLQEMESAVKSKYKASIAALEAKIAQLEEQLDNET 1828
Query: 371 EEINQAXXXXXXXXXXXXXIMALMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNA 550
+E A ++ + DE+R A+ +Q +KA+ R K+ +R L+ +E
Sbjct: 1829 KERQAASKQVRRAEKKLKDVLLQVEDERRNAEQFKDQADKASTRLKQLKRQLEEAEEEAQ 1888
Query: 551 ALTTQNRRLQRDLEEVNETKEARDQEIKVL 640
R+LQR+LE+ ET +A ++E+ L
Sbjct: 1889 RANASRRKLQRELEDATETADAMNREVSSL 1918
>sp|P14105|MYH9_CHICK Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy
chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin
heavy chain, type A) (Nonmuscle myosin heavy chain-A)
(NMMHC-A)
Length = 1959
Score = 100 bits (249), Expect = 5e-21
Identities = 63/210 (30%), Positives = 103/210 (49%)
Frame = +2
Query: 11 EEIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELN 190
+EIA + A+ +K+R+E+ ++ L + D+ KK Q++Q+ +LN
Sbjct: 1708 DEIANSSGKGALAMEEKRRLEARIAQLEEELEEEQGNTEIINDRLKKANLQIDQMNADLN 1767
Query: 191 VERQNATRLENQKSTAERLNXXXXXXXXXXXXXTGKKYKATVSAQQIKIQSLDAQLDAKI 370
ER NA + EN + ER N KYKAT++A + KI L+ QLD +
Sbjct: 1768 AERSNAQKNENARQQMERQNKELKLKLQEMESAVKSKYKATITALEAKIVQLEEQLDMET 1827
Query: 371 EEINQAXXXXXXXXXXXXXIMALMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNA 550
+E A I+ + DE+R A+ +Q +KA R K+ +R L+ E E A
Sbjct: 1828 KERQAASKQVRRAEKKLKDILLQVDDERRNAEQFKDQADKANMRLKQLKRQLE-EAEEEA 1886
Query: 551 ALTTQNRRLQRDLEEVNETKEARDQEIKVL 640
R+LQR+L++ ET +A ++E+ L
Sbjct: 1887 QRANVRRKLQRELDDATETADAMNREVSSL 1916
>sp|P35749|MYH11_HUMAN Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC)
Length = 1972
Score = 99.0 bits (245), Expect = 1e-20
Identities = 57/210 (27%), Positives = 100/210 (47%)
Frame = +2
Query: 11 EEIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELN 190
EE+A+ ++ +K+R+E+ ++ L + D+ +K T Q EQ+ NEL
Sbjct: 1715 EELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELA 1774
Query: 191 VERQNATRLENQKSTAERLNXXXXXXXXXXXXXTGKKYKATVSAQQIKIQSLDAQLDAKI 370
ER A + E+ + ER N K+K+T++A + KI L+ Q++ +
Sbjct: 1775 TERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEA 1834
Query: 371 EEINQAXXXXXXXXXXXXXIMALMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNA 550
E A I+ + DE++ A+ EQ EK R K+ +R L+ +E +
Sbjct: 1835 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQ 1894
Query: 551 ALTTQNRRLQRDLEEVNETKEARDQEIKVL 640
+ R+LQR+L+E E+ EA +E+ L
Sbjct: 1895 RINANRRKLQRELDEATESNEAMGREVNAL 1924
Score = 34.3 bits (77), Expect = 0.43
Identities = 42/224 (18%), Positives = 77/224 (34%), Gaps = 14/224 (6%)
Frame = +2
Query: 11 EEIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELN 190
+EI + + ++K +E +S L + K + + +++ L
Sbjct: 985 DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK 1044
Query: 191 VERQNATRLENQKSTAERLNXXXXXXXXXXXXXTGKKYKATVSAQQIKIQSLDAQLDAKI 370
E ++ LE K E + ++ Q +I L QL K
Sbjct: 1045 KEEKSRQELEKLKRKLE---------------GDASDFHEQIADLQAQIAELKMQLAKKE 1089
Query: 371 EEINQAXXXXXXXXXXXXXIMALMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNA 550
EE+ A +A + DE + +NA+++I + G + L E+
Sbjct: 1090 EELQAA--------------LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARN 1135
Query: 551 ALTTQNRRLQRDLEEVN--------------ETKEARDQEIKVL 640
Q R L +LE + E + R+QE+ VL
Sbjct: 1136 KAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVL 1179
>sp|Q61879|MYH10_MOUSE Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy
chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin
heavy chain, type B) (Nonmuscle myosin heavy chain-B)
(NMMHC-B)
Length = 1976
Score = 97.8 bits (242), Expect = 3e-20
Identities = 59/210 (28%), Positives = 96/210 (45%)
Frame = +2
Query: 11 EEIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELN 190
+EIA K + +K+R+E+ ++ L + D+ +K T Q++ + EL
Sbjct: 1715 DEIANSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNTELA 1774
Query: 191 VERQNATRLENQKSTAERLNXXXXXXXXXXXXXTGKKYKATVSAQQIKIQSLDAQLDAKI 370
ER A + +N + ER N K+KAT+SA + KI L+ QL+ +
Sbjct: 1775 AERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEA 1834
Query: 371 EEINQAXXXXXXXXXXXXXIMALMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNA 550
+E A I + DE+R AD EQ+EKA R K+ +R L+ +E
Sbjct: 1835 KERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEAT 1894
Query: 551 ALTTQNRRLQRDLEEVNETKEARDQEIKVL 640
R+LQR+L++ E E +E+ L
Sbjct: 1895 RANASRRKLQRELDDATEANEGLSREVSTL 1924
>sp|Q9JLT0|MYH10_RAT Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy
chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin
heavy chain, type B) (Nonmuscle myosin heavy chain-B)
(NMMHC-B)
Length = 1976
Score = 97.8 bits (242), Expect = 3e-20
Identities = 59/210 (28%), Positives = 96/210 (45%)
Frame = +2
Query: 11 EEIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELN 190
+EIA K + +K+R+E+ ++ L + D+ +K T Q++ + EL
Sbjct: 1715 DEIANSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNTELA 1774
Query: 191 VERQNATRLENQKSTAERLNXXXXXXXXXXXXXTGKKYKATVSAQQIKIQSLDAQLDAKI 370
ER A + +N + ER N K+KAT+SA + KI L+ QL+ +
Sbjct: 1775 AERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEA 1834
Query: 371 EEINQAXXXXXXXXXXXXXIMALMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNA 550
+E A I + DE+R AD EQ+EKA R K+ +R L+ +E
Sbjct: 1835 KERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEAT 1894
Query: 551 ALTTQNRRLQRDLEEVNETKEARDQEIKVL 640
R+LQR+L++ E E +E+ L
Sbjct: 1895 RANASRRKLQRELDDATEANEGLSREVSTL 1924
>sp|Q27991|MYH10_BOVIN Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy
chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin
heavy chain, type B) (Nonmuscle myosin heavy chain-B)
(NMMHC-B)
Length = 1976
Score = 97.8 bits (242), Expect = 3e-20
Identities = 59/210 (28%), Positives = 96/210 (45%)
Frame = +2
Query: 11 EEIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELN 190
+EIA K + +K+R+E+ ++ L + D+ +K T Q++ + EL
Sbjct: 1715 DEIANSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNTELA 1774
Query: 191 VERQNATRLENQKSTAERLNXXXXXXXXXXXXXTGKKYKATVSAQQIKIQSLDAQLDAKI 370
ER A + +N + ER N K+KAT+SA + KI L+ QL+ +
Sbjct: 1775 AERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEA 1834
Query: 371 EEINQAXXXXXXXXXXXXXIMALMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNA 550
+E A I + DE+R AD EQ+EKA R K+ +R L+ +E
Sbjct: 1835 KERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEAT 1894
Query: 551 ALTTQNRRLQRDLEEVNETKEARDQEIKVL 640
R+LQR+L++ E E +E+ L
Sbjct: 1895 RANASRRKLQRELDDATEANEGLSREVSTL 1924
>sp|P35748|MYH11_RABIT Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC)
Length = 1972
Score = 96.7 bits (239), Expect = 7e-20
Identities = 55/210 (26%), Positives = 100/210 (47%)
Frame = +2
Query: 11 EEIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELN 190
EE+A+ ++ +K+R+E+ ++ L + D+ +K T Q EQ+ NEL
Sbjct: 1715 EELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELA 1774
Query: 191 VERQNATRLENQKSTAERLNXXXXXXXXXXXXXTGKKYKATVSAQQIKIQSLDAQLDAKI 370
ER A + E+ + ER N K+K+T++A + KI L+ Q++ +
Sbjct: 1775 TERSTAQKNESARQQLERQNKELKSKLQEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEA 1834
Query: 371 EEINQAXXXXXXXXXXXXXIMALMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNA 550
E A ++ + DE++ A+ EQ EK + K+ +R L+ +E +
Sbjct: 1835 REKQAAAKALKQRDKKLKEMLLQVEDERKMAEQYKEQAEKGNAKVKQLKRQLEEAEEESQ 1894
Query: 551 ALTTQNRRLQRDLEEVNETKEARDQEIKVL 640
+ R+LQR+L+E E+ EA +E+ L
Sbjct: 1895 RINANRRKLQRELDEATESNEAMGREVNAL 1924
>sp|O08638|MYH11_MOUSE Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC)
Length = 1972
Score = 96.3 bits (238), Expect = 9e-20
Identities = 57/210 (27%), Positives = 100/210 (47%)
Frame = +2
Query: 11 EEIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELN 190
EE+A+ ++T +K+R+E+ ++ L + D+ +K T Q EQ+ NEL
Sbjct: 1715 EELASSLSGRNTLQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATLQAEQLSNELA 1774
Query: 191 VERQNATRLENQKSTAERLNXXXXXXXXXXXXXTGKKYKATVSAQQIKIQSLDAQLDAKI 370
ER A + E+ + ER N K K+TV+A + KI L+ Q++ +
Sbjct: 1775 TERSTAQKNESARQQLERQNKELRSKLQEVEGAVKAKLKSTVAALEAKIAQLEEQVEQEA 1834
Query: 371 EEINQAXXXXXXXXXXXXXIMALMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNA 550
E A ++ + DE++ A+ EQ EK + K+ +R L+ +E +
Sbjct: 1835 REKQAATKSLKQKDKKLKEVLLQVEDERKMAEQYKEQAEKGNTKVKQLKRQLEEAEEESQ 1894
Query: 551 ALTTQNRRLQRDLEEVNETKEARDQEIKVL 640
+ R+LQR+L+E E+ EA +E+ L
Sbjct: 1895 CINANRRKLQRELDEATESNEAMGREVNAL 1924
Score = 30.8 bits (68), Expect = 4.8
Identities = 39/209 (18%), Positives = 72/209 (34%), Gaps = 14/209 (6%)
Frame = +2
Query: 56 DKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELNVERQNATRLENQKST 235
++K +E +S L + K + + +++ L E ++ LE K
Sbjct: 1000 ERKLLEERVSDLTTNLAEEEEKAKNLTKLKSKHESMISELEVRLKKEEKSRQELEKLKRK 1059
Query: 236 AERLNXXXXXXXXXXXXXTGKKYKATVSAQQIKIQSLDAQLDAKIEEINQAXXXXXXXXX 415
E + ++ Q +I L QL K EE+ A
Sbjct: 1060 LE---------------GDASDFHEQIADLQAQIAELKMQLAKKEEELQAA--------- 1095
Query: 416 XXXXIMALMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNAALTTQNRRLQRDLEE 595
+A + +E + +NA+++I + G + L E+ Q R L +LE
Sbjct: 1096 -----LARLDEEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150
Query: 596 VN--------------ETKEARDQEIKVL 640
+ E + R+QE+ VL
Sbjct: 1151 LKTELEDTLDSTATQQELRAKREQEVTVL 1179
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,625,034
Number of Sequences: 369166
Number of extensions: 906852
Number of successful extensions: 3334
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2975
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3298
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8052550455
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)