Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_F04-1
(799 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P14314|GLU2B_HUMAN Glucosidase II beta subunit precursor... 145 1e-34
sp|O08795|GLU2B_MOUSE Glucosidase II beta subunit precursor... 142 1e-33
sp|Q28034|GLU2B_BOVIN Glucosidase II beta subunit precursor... 139 1e-32
sp|Q9USH8|YJQ2_SCHPO Hypothetical protein C825.02 in chromo... 116 8e-26
sp|P98158|LRP2_RAT Low-density lipoprotein receptor-related... 49 1e-05
sp|P98157|LRP1_CHICK Low-density lipoprotein receptor-relat... 47 5e-05
sp|Q07954|LRP1_HUMAN Low-density lipoprotein receptor-relat... 47 5e-05
sp|Q04833|LRP_CAEEL Low-density lipoprotein receptor-relate... 45 2e-04
sp|P34576|MUA3_CAEEL Transmembrane cell adhesion receptor m... 45 3e-04
sp|P98164|LRP2_HUMAN Low-density lipoprotein receptor-relat... 45 3e-04
>sp|P14314|GLU2B_HUMAN Glucosidase II beta subunit precursor (Protein kinase C substrate,
60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein)
Length = 527
Score = 145 bits (366), Expect = 1e-34
Identities = 61/104 (58%), Positives = 76/104 (73%)
Frame = +1
Query: 31 IEKPRGVPFSKLSFYQPNTPFKCLDGSGIINWMKVNDDYCDCRDATDEPGTSACSNGVFH 210
+++PRGV + FY + PF CLDGS I + +VNDDYCDC+D +DEPGT+AC NG FH
Sbjct: 17 VKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKDGSDEPGTAACPNGSFH 76
Query: 211 CDNKGHKSQLIPSSRVNDGICDCCDGQDEYSGIINCTNTCWELG 342
C N G+K IPS+RVNDG+CDCCDG DEY+ + C NTC E G
Sbjct: 77 CTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKG 120
Score = 53.5 bits (127), Expect = 6e-07
Identities = 32/101 (31%), Positives = 52/101 (51%)
Frame = +2
Query: 494 EKKARLETINEQFRTLSEEKLASERIKTDAETNEVEAKKVFEENWKKLQGENDKKLELSK 673
EK+ +L + ++L ++ +K +AE E EAK+ ++ W++ + E
Sbjct: 154 EKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQEL 213
Query: 674 ISKAFNELDIDADHKVSYEELQSHHEFDIDQNGDVSTKETK 796
+ AF ELD D D VS ELQ+H E D D +G +S E +
Sbjct: 214 AADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQ 254
>sp|O08795|GLU2B_MOUSE Glucosidase II beta subunit precursor (Protein kinase C substrate,
60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein)
Length = 521
Score = 142 bits (357), Expect = 1e-33
Identities = 61/104 (58%), Positives = 75/104 (72%)
Frame = +1
Query: 31 IEKPRGVPFSKLSFYQPNTPFKCLDGSGIINWMKVNDDYCDCRDATDEPGTSACSNGVFH 210
+++PRGV S FY+ + PF CLDG+ I + +VNDDYCDC+D +DEPGT+AC NG FH
Sbjct: 17 VKRPRGVSLSNHHFYEESKPFTCLDGTATIPFDQVNDDYCDCKDGSDEPGTAACPNGSFH 76
Query: 211 CDNKGHKSQLIPSSRVNDGICDCCDGQDEYSGIINCTNTCWELG 342
C N G+K I SSRVNDG+CDCCDG DEY+ C NTC E G
Sbjct: 77 CTNTGYKPLYILSSRVNDGVCDCCDGTDEYNSGTVCENTCREKG 120
Score = 56.2 bits (134), Expect = 1e-07
Identities = 33/111 (29%), Positives = 59/111 (53%)
Frame = +2
Query: 464 LLLKYEISVIEKKARLETINEQFRTLSEEKLASERIKTDAETNEVEAKKVFEENWKKLQG 643
L+ +++ + EK+++L + ++L ++ K +AE E EAK + W++ Q
Sbjct: 144 LIEEWKTAREEKQSKLLELQAGKKSLEDQVETLRAAKEEAERPEKEAKDQHRKLWEEQQA 203
Query: 644 ENDKKLELSKISKAFNELDIDADHKVSYEELQSHHEFDIDQNGDVSTKETK 796
+ E + + AF ELD + D VS ELQ+H E D D +G +S +E +
Sbjct: 204 AAKARREQERAASAFQELDDNMDGMVSLAELQTHPELDTDGDGALSEEEAQ 254
>sp|Q28034|GLU2B_BOVIN Glucosidase II beta subunit precursor (Protein kinase C substrate,
60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein)
(Vacuolar system associated protein 60) (VASAP-60)
Length = 533
Score = 139 bits (349), Expect = 1e-32
Identities = 60/104 (57%), Positives = 73/104 (70%)
Frame = +1
Query: 31 IEKPRGVPFSKLSFYQPNTPFKCLDGSGIINWMKVNDDYCDCRDATDEPGTSACSNGVFH 210
+ +PRGV + FY + PF CLDGS I + +VNDDYCDC+D +DEPGT+AC NG FH
Sbjct: 16 VRRPRGVSLTNHHFYDESKPFTCLDGSASIPFDQVNDDYCDCKDGSDEPGTAACPNGSFH 75
Query: 211 CDNKGHKSQLIPSSRVNDGICDCCDGQDEYSGIINCTNTCWELG 342
C N G+K+ I S VNDG+CDCCDG DEY+ I C NTC E G
Sbjct: 76 CTNTGYKALYISSRWVNDGVCDCCDGTDEYNSGIVCENTCKEKG 119
Score = 53.5 bits (127), Expect = 6e-07
Identities = 32/101 (31%), Positives = 51/101 (50%)
Frame = +2
Query: 494 EKKARLETINEQFRTLSEEKLASERIKTDAETNEVEAKKVFEENWKKLQGENDKKLELSK 673
EK+ +L + ++L ++ +K +AE E AK W++ Q + ++ E
Sbjct: 153 EKQKKLIELQAGKKSLEDQVEVLRTLKEEAEKPEEAAKDQHRRLWEEQQAISKEQREREL 212
Query: 674 ISKAFNELDIDADHKVSYEELQSHHEFDIDQNGDVSTKETK 796
+ AF ELD D D VS ELQ+H E D D +G +S E +
Sbjct: 213 AASAFQELDDDMDGAVSVAELQTHPELDTDGDGALSEGEAQ 253
>sp|Q9USH8|YJQ2_SCHPO Hypothetical protein C825.02 in chromosome III precursor
Length = 506
Score = 116 bits (290), Expect = 8e-26
Identities = 55/111 (49%), Positives = 70/111 (63%), Gaps = 2/111 (1%)
Frame = +1
Query: 4 IIS*FHITCIEKPRGVPFSKLSFYQPNTP--FKCLDGSGIINWMKVNDDYCDCRDATDEP 177
I S + + RGV K Y+P+ +KCL +I++ +VNDDYCDC D +DEP
Sbjct: 15 ISSLYTVNAANDLRGVASDKSDLYKPDAKGNWKCLGSDKLISFNQVNDDYCDCPDGSDEP 74
Query: 178 GTSACSNGVFHCDNKGHKSQLIPSSRVNDGICDCCDGQDEYSGIINCTNTC 330
GTSAC NG F C N G+ S IPS+RV+D +CDCCDG DE +I C NTC
Sbjct: 75 GTSACHNGKFFCKNTGYISSYIPSNRVDDTVCDCCDGSDE--SLIKCPNTC 123
>sp|P98158|LRP2_RAT Low-density lipoprotein receptor-related protein 2 precursor
(Megalin) (Glycoprotein 330) (gp330)
Length = 4660
Score = 49.3 bits (116), Expect = 1e-05
Identities = 30/79 (37%), Positives = 36/79 (45%), Gaps = 5/79 (6%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEPG-----TSACSNGVFHCDNKGHKSQLIPSSR 255
FKC DGS IN D DCRD +DE G C F C G IP++
Sbjct: 1193 FKCADGSSCINSRYRCDGVYDCRDNSDEAGCPTRPPGMCHPDEFQCQGDG---TCIPNTW 1249
Query: 256 VNDGICDCCDGQDEYSGII 312
DG DC G DE++G +
Sbjct: 1250 ECDGHPDCIHGSDEHTGCV 1268
Score = 41.6 bits (96), Expect = 0.003
Identities = 33/82 (40%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Frame = +1
Query: 91 FKCLDGSGI-INWMKVNDDYCDCRDATDEPGTS--ACSNGVFHCDNKGHKSQLIPSSRVN 261
F+C +G I +W D DC D TDE G +C +G+F C +G IPSS V
Sbjct: 33 FRCDNGYCIPASWRC--DGTRDCLDDTDEIGCPPRSCESGLFLCPAEG---TCIPSSWVC 87
Query: 262 DGICDCCDGQDEYSGIINCTNT 327
D DC DG DE NC T
Sbjct: 88 DEDKDCSDGADEQQ---NCAGT 106
Score = 40.8 bits (94), Expect = 0.004
Identities = 31/85 (36%), Positives = 37/85 (43%), Gaps = 3/85 (3%)
Frame = +1
Query: 79 PNTPFKCLDGSGIINWMKVNDDYCDCRDATDEPGTSA---CSNGVFHCDNKGHKSQLIPS 249
P+T F C D I V D DC D +DE A C F C + S L
Sbjct: 1111 PSTSFTC-DNHVCIPKDWVCDTDNDCSDGSDEKNCQASGTCQPTQFRCPDHRCISPLY-- 1167
Query: 250 SRVNDGICDCCDGQDEYSGIINCTN 324
V DG DC DG DE ++NCT+
Sbjct: 1168 --VCDGDKDCADGSDEAGCVLNCTS 1190
Score = 40.0 bits (92), Expect = 0.007
Identities = 29/88 (32%), Positives = 38/88 (43%), Gaps = 9/88 (10%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEPGT-----SACSNGVFHCDNKGHKSQLIPSSR 255
F+CL I D DC D +DEP T + C F CDN + I +
Sbjct: 2870 FQCLSPQRCIPSYWFCDGEADCADGSDEPDTCGHSVNTCRASQFQCDN----GRCISGNW 2925
Query: 256 VNDGICDCCDGQDE----YSGIINCTNT 327
V DG DC D DE + + NC++T
Sbjct: 2926 VCDGDNDCGDMSDEDQRHHCELQNCSST 2953
Score = 39.7 bits (91), Expect = 0.010
Identities = 26/70 (37%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Frame = +1
Query: 127 MKVNDDYCDCR-DATDEPGTSACSNGVFHCDNKGHKSQLIPSSRVNDGICDCCDGQDEYS 303
MK+ D C D EP T C + F C+N + +PS DG+ DC D DE+
Sbjct: 1003 MKLQRDQMTCEGDPAREPPTQQCGSLSFPCNN----GKCVPSFFRCDGVDDCHDNSDEHQ 1058
Query: 304 -GIINCTNTC 330
G+ N NTC
Sbjct: 1059 CGVFN--NTC 1066
Score = 37.0 bits (84), Expect = 0.062
Identities = 29/99 (29%), Positives = 42/99 (42%), Gaps = 19/99 (19%)
Frame = +1
Query: 91 FKCLDGSGII-NWMKVNDDYCDCRDATDEPGTSA------CSNGVFHCDNKGHKSQLIPS 249
F C +G I NW+ DD DC+D+ DE G + C + C G + I
Sbjct: 227 FTCSNGQCINQNWVCDGDD--DCQDSGDEDGCESNQSHHRCYpreWACPGSG---RCISI 281
Query: 250 SRVNDGICDCCDGQDEYS------------GIINCTNTC 330
+V DG+ DC +G DE + ++NC C
Sbjct: 282 DKVCDGVPDCPEGDDENNVTSGRTCGMGVCSVLNCEYQC 320
Score = 36.2 bits (82), Expect = 0.11
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 5/76 (6%)
Frame = +1
Query: 85 TPFKCLDGSGIIN-WMKVNDDYCDCRDATDEPGTSACSNGVFHCDNKGHK----SQLIPS 249
T F C +G+ I W+ D+ DCRD +DE C FHC + + S I
Sbjct: 1275 THFLCDNGNCIYKAWICDGDN--DCRDMSDEKD---CPTQPFHCPSTQWQCPGYSTCINL 1329
Query: 250 SRVNDGICDCCDGQDE 297
S + DG+ DC +G DE
Sbjct: 1330 SALCDGVFDCPNGTDE 1345
Score = 35.8 bits (81), Expect = 0.14
Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 4/64 (6%)
Frame = +1
Query: 151 DCRDATDEP----GTSACSNGVFHCDNKGHKSQLIPSSRVNDGICDCCDGQDEYSGIINC 318
DC D +DE + C + F C + + IPS DG DC DG DE +
Sbjct: 2848 DCGDGSDENPIYCASHTCRSNEFQCLSP---QRCIPSYWFCDGEADCADGSDEPDTCGHS 2904
Query: 319 TNTC 330
NTC
Sbjct: 2905 VNTC 2908
Score = 35.0 bits (79), Expect = 0.24
Identities = 25/75 (33%), Positives = 31/75 (41%), Gaps = 3/75 (4%)
Frame = +1
Query: 82 NTPFKCLDGSGIINWMKVNDDYCDCRDATDEPGTSAC---SNGVFHCDNKGHKSQLIPSS 252
+T F C I V + + DCRD +DE G + +G F C N IP
Sbjct: 3683 HTEFSCKTNYRCIPQWAVCNGFDDCRDNSDEQGCESVPCHPSGDFRCAN----HHCIPLR 3738
Query: 253 RVNDGICDCCDGQDE 297
DG DC D DE
Sbjct: 3739 WKCDGTDDCGDNSDE 3753
Score = 35.0 bits (79), Expect = 0.24
Identities = 25/76 (32%), Positives = 32/76 (42%), Gaps = 7/76 (9%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDE-------PGTSACSNGVFHCDNKGHKSQLIPS 249
F+C G + + D DC DA+DE P + C +F C N I S
Sbjct: 3805 FQCTSGHCVPKALAC-DGRADCLDASDESACPTRFPNGTYCPAAMFECKNH----VCIQS 3859
Query: 250 SRVNDGICDCCDGQDE 297
+ DG DC DG DE
Sbjct: 3860 FWICDGENDCVDGSDE 3875
Score = 34.3 bits (77), Expect = 0.40
Identities = 23/58 (39%), Positives = 25/58 (43%), Gaps = 3/58 (5%)
Frame = +1
Query: 133 VNDDYCDCRDATDEPGTSA---CSNGVFHCDNKGHKSQLIPSSRVNDGICDCCDGQDE 297
V D+ DC D DE A CS C N Q IPS D + DC DG DE
Sbjct: 86 VCDEDKDCSDGADEQQNCAGTTCSAQQMTCSN----GQCIPSEYRCDHVSDCPDGSDE 139
Score = 33.1 bits (74), Expect = 0.90
Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 5/85 (5%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEPG----TSACSNGVFHCDNKGHKSQLIPSSRV 258
F C +G + ++ + D DC D +DE + CS F C G Q IP
Sbjct: 1030 FPCNNGKCVPSFFRC-DGVDDCHDNSDEHQCGVFNNTCSPSAFACVRGG---QCIPGQWH 1085
Query: 259 NDGICDCCDGQDEYSGIINCT-NTC 330
D DC DG DE + + T +TC
Sbjct: 1086 CDRQNDCLDGSDEQNCPTHATSSTC 1110
Score = 32.3 bits (72), Expect = 1.5
Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 3/76 (3%)
Frame = +1
Query: 79 PNTPFKCLDGSGI-INWMKVNDDYCDCRDATDEPGT--SACSNGVFHCDNKGHKSQLIPS 249
P+ F+C + I + W D DC D +DE CS F C ++ Q IPS
Sbjct: 3723 PSGDFRCANHHCIPLRWKCDGTD--DCGDNSDEENCVpreCSESEFRCADQ----QCIPS 3776
Query: 250 SRVNDGICDCCDGQDE 297
V D DC D DE
Sbjct: 3777 RWVCDQENDCGDNSDE 3792
Score = 32.0 bits (71), Expect = 2.0
Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
Frame = +1
Query: 139 DDYCDCRDATDEPG-TSACSNGVFHCDNKGHKSQLIPSSRVNDGICDCCDGQDEYSGIIN 315
D DCRD++DE T+ CS F C + + I + V D DC D DE N
Sbjct: 165 DQKVDCRDSSDEANCTTLCSQKEFECGS----GECILRAYVCDHDNDCEDNSDER----N 216
Query: 316 CT-NTC 330
C +TC
Sbjct: 217 CNYDTC 222
Score = 30.0 bits (66), Expect = 7.6
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 6/81 (7%)
Frame = +1
Query: 73 YQPNTPFKCLDGSGIINWMKVNDDYCDCRDATDEPGTSACSN------GVFHCDNKGHKS 234
Y P F+C + I ++ + D DC D +DE C N F CDN S
Sbjct: 3843 YCPAAMFECKNHVCIQSFW-ICDGENDCVDGSDEE-IHLCFNIPCESPQRFRCDN----S 3896
Query: 235 QLIPSSRVNDGICDCCDGQDE 297
+ + ++ +G+ DC DG DE
Sbjct: 3897 RCVYGHQLCNGVDDCGDGSDE 3917
Score = 29.6 bits (65), Expect = 9.9
Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Frame = +1
Query: 82 NTPFKCLDGSGIINWMKVNDDYCDCRDATDEPG---TSACSNGVFHCDNKGHKSQLIPSS 252
+T F C +G + + D Y DC D +DE G + S F C N + IP S
Sbjct: 2744 STAFTCGNGRCVPYHYRC-DYYNDCGDNSDEAGCLFRNCNSTTEFTCSN----GRCIPLS 2798
Query: 253 RVNDGICDCCDGQDEYSGIINC-TNTC 330
V +GI +C D ++ S NC +TC
Sbjct: 2799 YVCNGINNCHD--NDTSDEKNCPPHTC 2823
>sp|P98157|LRP1_CHICK Low-density lipoprotein receptor-related protein 1 precursor (LRP)
(Alpha-2-macroglobulin receptor) (A2MR)
Length = 4543
Score = 47.4 bits (111), Expect = 5e-05
Identities = 35/84 (41%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +1
Query: 79 PNTPFKCLDGSGI-INWMKVNDDYCDCRDATDEPGTS-ACSNGVFHCDNKGHKSQLIPSS 252
P T F C +G I INW ND+ DC D +DE G S +CS+ F C++ + IP
Sbjct: 976 PLTQFTCNNGRCININWRCDNDN--DCGDNSDEAGCSHSCSSNQFKCNS----GRCIPVH 1029
Query: 253 RVNDGICDCCDGQDEYSGIINCTN 324
DG DC D DE NCTN
Sbjct: 1030 WTCDGDNDCGDYSDETHA--NCTN 1051
Score = 40.8 bits (94), Expect = 0.004
Identities = 26/75 (34%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Frame = +1
Query: 79 PNTPFKCLDGSGIINWMKVNDDYCDCRDATDEPGTSA--CSNGVFHCDNKGHKSQLIPSS 252
PN F C D + I+ V D DC D +DE + C C N + S +P
Sbjct: 1104 PNVKFGCKDSARCISKAWVCDGDSDCEDNSDEENCESLVCKPPSHTCAN--NTSICLPPE 1161
Query: 253 RVNDGICDCCDGQDE 297
++ DG DC DG DE
Sbjct: 1162 KLCDGSDDCGDGSDE 1176
Score = 40.8 bits (94), Expect = 0.004
Identities = 37/99 (37%), Positives = 45/99 (45%), Gaps = 9/99 (9%)
Frame = +1
Query: 28 CIEKPRGVPFSKLSFYQPNTPFKCLDGSGIINWMKVNDDYCDCRDATDEPGTSA--CSNG 201
C + VP +K S T F+C DGS I N + N + DC DA+DE +A CS+
Sbjct: 2585 CGDNSDEVPCNKTSCAA--TEFRCRDGSCIGNSSRCNQ-FIDCEDASDEMNCTATDCSS- 2640
Query: 202 VFHCDNKG-------HKSQLIPSSRVNDGICDCCDGQDE 297
F KG H S S V DG DC D DE
Sbjct: 2641 YFKLGVKGTTFQKCEHTSLCYAPSWVCDGANDCGDYSDE 2679
Score = 40.8 bits (94), Expect = 0.004
Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 9/87 (10%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEPGT--------SACSNGVFHCDNKGHKSQLIP 246
F+C +G + N D DC D +DE S C++ F C N + IP
Sbjct: 2861 FRCANGRCLSNSQWECDGEFDCHDHSDEAPKNPRCSSPESKCNDSFFMCKN----GKCIP 2916
Query: 247 SSRVNDGICDCCDGQDEYSGIIN-CTN 324
+ + D DC DG DE + IN C N
Sbjct: 2917 EALLCDNNNDCADGSDELNCFINECLN 2943
Score = 34.3 bits (77), Expect = 0.40
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 3/72 (4%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEPGT---SACSNGVFHCDNKGHKSQLIPSSRVN 261
F+C + I+ + V D DC D +DE + CS G F C +P +
Sbjct: 2737 FEC-NNHRCISKLWVCDGADDCGDGSDEDSRCRLTTCSTGSFQCPGT---YVCVPERWLC 2792
Query: 262 DGICDCCDGQDE 297
DG DC DG DE
Sbjct: 2793 DGDKDCADGADE 2804
Score = 32.3 bits (72), Expect = 1.5
Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 10/85 (11%)
Frame = +1
Query: 79 PNTPFKCLDG----------SGIINWMKVNDDYCDCRDATDEPGTSACSNGVFHCDNKGH 228
PN PF+C + GI N N D DC T +P + + F C+NK
Sbjct: 3694 PNRPFRCKNDRVCLWIGRQCDGIDNCGD-NTDEKDCESPTAKPKSCSQDKNEFLCENK-- 3750
Query: 229 KSQLIPSSRVNDGICDCCDGQDEYS 303
+ I ++ + DC DG DE S
Sbjct: 3751 --KCISANLRCNFFDDCGDGSDEKS 3773
Score = 32.0 bits (71), Expect = 2.0
Identities = 21/58 (36%), Positives = 24/58 (41%), Gaps = 2/58 (3%)
Frame = +1
Query: 151 DCRDATDEPGTSA--CSNGVFHCDNKGHKSQLIPSSRVNDGICDCCDGQDEYSGIINC 318
DC D +DE + CS F C N + I DG DC DG DE I C
Sbjct: 3557 DCGDNSDEESCTPRPCSESEFSCAN----GRCIAGRWKCDGDHDCADGSDEKDCIPRC 3610
Score = 30.8 bits (68), Expect = 4.5
Identities = 25/85 (29%), Positives = 33/85 (38%), Gaps = 8/85 (9%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEPGTSACSNGVFHCDNKGHK----SQLIPSSRV 258
F C D I+ D DC D +DE + V C H I S++
Sbjct: 34 FACKDQITCISKGWRCDGEKDCPDGSDESPDICPQSKVSRCQPNEHNCLGTELCIHMSKL 93
Query: 259 NDGICDCCDGQDE----YSGIINCT 321
+G+ DC DG DE + NCT
Sbjct: 94 CNGLHDCFDGSDEGPHCREQLANCT 118
Score = 30.0 bits (66), Expect = 7.6
Identities = 20/55 (36%), Positives = 22/55 (40%), Gaps = 6/55 (10%)
Frame = +1
Query: 151 DCRDATDEP------GTSACSNGVFHCDNKGHKSQLIPSSRVNDGICDCCDGQDE 297
DC D DE + C F C N+ Q IP V D DC DG DE
Sbjct: 2797 DCADGADETLAAGCLYNNTCDEREFMCGNR----QCIPKHFVCDHDDDCGDGSDE 2847
Score = 29.6 bits (65), Expect = 9.9
Identities = 28/81 (34%), Positives = 33/81 (40%), Gaps = 6/81 (7%)
Frame = +1
Query: 79 PNTPFKCLDGSGI-INWMKVNDDYCDCRDATDEPGTSA-----CSNGVFHCDNKGHKSQL 240
P F C G I + W +D DC + DE S C F C+N S+L
Sbjct: 2691 PANYFACPSGRCIPMTWTCDKED--DCENGEDETHCSERQDKFCYPVQFECNNHRCISKL 2748
Query: 241 IPSSRVNDGICDCCDGQDEYS 303
V DG DC DG DE S
Sbjct: 2749 W----VCDGADDCGDGSDEDS 2765
Score = 29.6 bits (65), Expect = 9.9
Identities = 23/75 (30%), Positives = 28/75 (37%), Gaps = 4/75 (5%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEP----GTSACSNGVFHCDNKGHKSQLIPSSRV 258
F+C D I D DC D +DEP C F C N ++ +P
Sbjct: 3496 FRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCKN----NRCVPGRWQ 3551
Query: 259 NDGICDCCDGQDEYS 303
D DC D DE S
Sbjct: 3552 CDYDNDCGDNSDEES 3566
>sp|Q07954|LRP1_HUMAN Low-density lipoprotein receptor-related protein 1 precursor (LRP)
(Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E
receptor) (APOER) (CD91)
Length = 4544
Score = 47.4 bits (111), Expect = 5e-05
Identities = 35/84 (41%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +1
Query: 79 PNTPFKCLDGSGI-INWMKVNDDYCDCRDATDEPGTS-ACSNGVFHCDNKGHKSQLIPSS 252
P T F C +G I INW ND+ DC D +DE G S +CS+ F C++ + IP
Sbjct: 978 PLTQFTCNNGRCININWRCDNDN--DCGDNSDEAGCSHSCSSTQFKCNS----GRCIPEH 1031
Query: 253 RVNDGICDCCDGQDEYSGIINCTN 324
DG DC D DE NCTN
Sbjct: 1032 WTCDGDNDCGDYSDETHA--NCTN 1053
Score = 38.9 bits (89), Expect = 0.016
Identities = 26/75 (34%), Positives = 35/75 (46%), Gaps = 2/75 (2%)
Frame = +1
Query: 79 PNTPFKCLDGSGIINWMKVNDDYCDCRDATDEPG--TSACSNGVFHCDNKGHKSQLIPSS 252
P+ F C D + I+ V D DC D +DE + AC C N + S +P
Sbjct: 1106 PSVKFGCKDSARCISKAWVCDGDNDCEDNSDEENCESLACRPPSHPCAN--NTSVCLPPD 1163
Query: 253 RVNDGICDCCDGQDE 297
++ DG DC DG DE
Sbjct: 1164 KLCDGNDDCGDGSDE 1178
Score = 35.8 bits (81), Expect = 0.14
Identities = 30/78 (38%), Positives = 36/78 (46%), Gaps = 9/78 (11%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEPGTSA--CSNGVFHCDNKG-------HKSQLI 243
F+C DG+ I N + N + DC DA+DE SA CS+ F KG S
Sbjct: 2610 FRCRDGTCIGNSSRCNQ-FVDCEDASDEMNCSATDCSS-YFRLGVKGVLFQPCERTSLCY 2667
Query: 244 PSSRVNDGICDCCDGQDE 297
S V DG DC D DE
Sbjct: 2668 APSWVCDGANDCGDYSDE 2685
Score = 34.7 bits (78), Expect = 0.31
Identities = 25/88 (28%), Positives = 32/88 (36%), Gaps = 4/88 (4%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEPGTSACSNGVFHCDNKGHK----SQLIPSSRV 258
F C D I+ D DC D +DE + C H +P SR+
Sbjct: 32 FACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTELCVPMSRL 91
Query: 259 NDGICDCCDGQDEYSGIINCTNTCWELG 342
+G+ DC DG DE C LG
Sbjct: 92 CNGVQDCMDGSDEGPHCRELQGNCSRLG 119
Score = 33.9 bits (76), Expect = 0.53
Identities = 29/96 (30%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Frame = +1
Query: 22 ITCIEKPRGVPFSKLSFYQPNTPFKCLDGSGIINWMKVNDDYCDCRDATDEPGT----SA 189
+TC+ P VP + QP F C + I K + D DC D +DE
Sbjct: 840 VTCLANPSYVPPPQC---QPGE-FACANSRCIQERWKCDGDN-DCLDNSDEAPALCHQHT 894
Query: 190 CSNGVFHCDNKGHKSQLIPSSRVNDGICDCCDGQDE 297
C + F C+N ++ IP+ + DG DC + +DE
Sbjct: 895 CPSDRFKCEN----NRCIPNRWLCDGDNDCGNSEDE 926
Score = 33.1 bits (74), Expect = 0.90
Identities = 21/55 (38%), Positives = 23/55 (41%), Gaps = 6/55 (10%)
Frame = +1
Query: 151 DCRDATDEP------GTSACSNGVFHCDNKGHKSQLIPSSRVNDGICDCCDGQDE 297
DC D DE S C + F C N+ Q IP V D DC DG DE
Sbjct: 2799 DCADGADESIAAGCLYNSTCDDREFMCQNR----QCIPKHFVCDHDRDCADGSDE 2849
Score = 32.0 bits (71), Expect = 2.0
Identities = 25/75 (33%), Positives = 31/75 (41%), Gaps = 2/75 (2%)
Frame = +1
Query: 79 PNTPFKCLDGSGI-INWMKVNDDYCDCRDATDEPGTSA-CSNGVFHCDNKGHKSQLIPSS 252
P F C G I ++W +D DC DE + CS F C N + I
Sbjct: 2697 PLNYFACPSGRCIPMSWTCDKED--DCEHGEDETHCNKFCSEAQFECQNH----RCISKQ 2750
Query: 253 RVNDGICDCCDGQDE 297
+ DG DC DG DE
Sbjct: 2751 WLCDGSDDCGDGSDE 2765
Score = 31.6 bits (70), Expect = 2.6
Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 2/62 (3%)
Frame = +1
Query: 151 DCRDATDEPGTSA--CSNGVFHCDNKGHKSQLIPSSRVNDGICDCCDGQDEYSGIINCTN 324
DC D +DE + CS F C N + I DG DC DG DE +CT
Sbjct: 3560 DCGDNSDEESCTPRPCSESEFSCAN----GRCIAGRWKCDGDHDCADGSDEK----DCTP 3611
Query: 325 TC 330
C
Sbjct: 3612 RC 3613
Score = 29.6 bits (65), Expect = 9.9
Identities = 23/75 (30%), Positives = 28/75 (37%), Gaps = 4/75 (5%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEP----GTSACSNGVFHCDNKGHKSQLIPSSRV 258
F+C D I D DC D +DEP C F C N ++ +P
Sbjct: 3499 FRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCKN----NRCVPGRWQ 3554
Query: 259 NDGICDCCDGQDEYS 303
D DC D DE S
Sbjct: 3555 CDYDNDCGDNSDEES 3569
>sp|Q04833|LRP_CAEEL Low-density lipoprotein receptor-related protein precursor (LRP)
Length = 4753
Score = 45.4 bits (106), Expect = 2e-04
Identities = 29/74 (39%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEPGT-----SACSNGVFHCDNKGHKSQLIPSSR 255
F C DG + K D DCRD +DE + +AC F C +K +Q I S
Sbjct: 144 FMCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADK---TQCIQKSW 200
Query: 256 VNDGICDCCDGQDE 297
V DG DC DG DE
Sbjct: 201 VCDGSKDCADGSDE 214
Score = 40.0 bits (92), Expect = 0.007
Identities = 26/71 (36%), Positives = 29/71 (40%), Gaps = 9/71 (12%)
Frame = +1
Query: 145 YCD----CRDATDEPGTSACSN-----GVFHCDNKGHKSQLIPSSRVNDGICDCCDGQDE 297
YCD CRD +DEPG S C G F C N ++ DG DC D DE
Sbjct: 3647 YCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPF----QICDGNDDCGDSSDE 3702
Query: 298 YSGIINCTNTC 330
NC C
Sbjct: 3703 Q----NCDKAC 3709
Score = 38.9 bits (89), Expect = 0.016
Identities = 27/71 (38%), Positives = 33/71 (46%), Gaps = 3/71 (4%)
Frame = +1
Query: 139 DDYCDCRDATDEP--GTSACSNGVFHCDNKGHKSQLIPSSRVNDGICDCCDGQDEYSGII 312
D Y DC D +DE G C G ++C GH I ++ DG DC DG DE
Sbjct: 243 DYYDDCGDNSDEDECGEYRCPPGKWNCPGTGH---CIDQLKLCDGSKDCADGADEQ---- 295
Query: 313 NCT-NTCWELG 342
C+ N C LG
Sbjct: 296 QCSQNLCPSLG 306
Score = 38.9 bits (89), Expect = 0.016
Identities = 28/82 (34%), Positives = 36/82 (43%)
Frame = +1
Query: 73 YQPNTPFKCLDGSGIINWMKVNDDYCDCRDATDEPGTSACSNGVFHCDNKGHKSQLIPSS 252
Y T +C+D + N + DD D D D P AC+ G F C N GH I +
Sbjct: 2838 YNLCTNRRCIDSAKKCNHI---DDCGDGSDELDCPSAVACAEGTFPCSN-GH---CINQT 2890
Query: 253 RVNDGICDCCDGQDEYSGIINC 318
+V DG DC D Q + C
Sbjct: 2891 KVCDGHNDCHDEQVSDESLATC 2912
Score = 38.1 bits (87), Expect = 0.028
Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 4/73 (5%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEPGTS----ACSNGVFHCDNKGHKSQLIPSSRV 258
F+C +G + D DC D +DE + +C+ F C + G IP+S
Sbjct: 1233 FRCANGRQCVPLRNHCDGQSDCEDGSDEDSCAVTAESCTPDQFKCVSSG---LCIPASWK 1289
Query: 259 NDGICDCCDGQDE 297
DG DC DG DE
Sbjct: 1290 CDGQQDCDDGSDE 1302
Score = 36.2 bits (82), Expect = 0.11
Identities = 25/72 (34%), Positives = 30/72 (41%), Gaps = 3/72 (4%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEPGT---SACSNGVFHCDNKGHKSQLIPSSRVN 261
F+C D + I V D DC D +DEP T C+ F C NK + P
Sbjct: 187 FRCADKTQCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNK----RCQPRKFRC 242
Query: 262 DGICDCCDGQDE 297
D DC D DE
Sbjct: 243 DYYDDCGDNSDE 254
Score = 36.2 bits (82), Expect = 0.11
Identities = 29/76 (38%), Positives = 33/76 (43%), Gaps = 5/76 (6%)
Frame = +1
Query: 91 FKCLDGSGI-INWMKVNDDYCDCRDATDEPGTSA----CSNGVFHCDNKGHKSQLIPSSR 255
F C +G I I W+ D+ DC D TDE CS F C N Q +P
Sbjct: 1192 FSCANGRCIPIYWLCDGDN--DCYDGTDEDKERCPPVQCSALQFRCANG---RQCVPLRN 1246
Query: 256 VNDGICDCCDGQDEYS 303
DG DC DG DE S
Sbjct: 1247 HCDGQSDCEDGSDEDS 1262
Score = 35.8 bits (81), Expect = 0.14
Identities = 25/72 (34%), Positives = 29/72 (40%), Gaps = 3/72 (4%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEPGTS--ACSNGVFHCDN-KGHKSQLIPSSRVN 261
F+C DG I K D DC D DE C + + CD H I +
Sbjct: 58 FRCNDGKCIRTEWKC-DGSGDCSDGEDEKDCPHPGCKSDQWQCDTYTWHSVSCIAEYQRC 116
Query: 262 DGICDCCDGQDE 297
D I DC DG DE
Sbjct: 117 DNITDCADGSDE 128
Score = 35.8 bits (81), Expect = 0.14
Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 5/76 (6%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEP-----GTSACSNGVFHCDNKGHKSQLIPSSR 255
FKC+ I D DC D +DEP CS+ F C N + I ++
Sbjct: 1275 FKCVSSGLCIPASWKCDGQQDCDDGSDEPKFGCTSGRQCSSDQFKCGN----GRCILNNW 1330
Query: 256 VNDGICDCCDGQDEYS 303
+ DG DC DG DE S
Sbjct: 1331 LCDGENDCGDGSDESS 1346
Score = 35.4 bits (80), Expect = 0.18
Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 9/80 (11%)
Frame = +1
Query: 91 FKCLDGSGIINWMKV--NDDYCDCRDATDEPGTSA-------CSNGVFHCDNKGHKSQLI 243
F+C + + N K NDD D D D P SA CSNG F C + + I
Sbjct: 3145 FQCANHKCVPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTS----GECI 3200
Query: 244 PSSRVNDGICDCCDGQDEYS 303
++V D DC D DE S
Sbjct: 3201 DDAKVCDRNFDCTDRSDESS 3220
Score = 35.0 bits (79), Expect = 0.24
Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 9/78 (11%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEP-----GTSACSNGVFHCDNKGH----KSQLI 243
F+C D I+ + D DC D +DE G C++ FHC + K + I
Sbjct: 3012 FQC-DNLKCISRAFICDGEDDCGDGSDEHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECI 3070
Query: 244 PSSRVNDGICDCCDGQDE 297
P + + DG C G+DE
Sbjct: 3071 PRAWLCDGDVTCAGGEDE 3088
Score = 34.7 bits (78), Expect = 0.31
Identities = 26/72 (36%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEPGT---SACSNGVFHCDNKGHKSQLIPSSRVN 261
F+C + I + + + D DC D +DE S+C F C N HK +P+S
Sbjct: 3105 FRCSNQHCIHSTWECDGDN-DCLDGSDEHANCTYSSCQPDFFQCAN--HKC--VPNSWKC 3159
Query: 262 DGICDCCDGQDE 297
DG DC DG DE
Sbjct: 3160 DGNDDCEDGSDE 3171
Score = 32.0 bits (71), Expect = 2.0
Identities = 18/44 (40%), Positives = 23/44 (52%)
Frame = +1
Query: 190 CSNGVFHCDNKGHKSQLIPSSRVNDGICDCCDGQDEYSGIINCT 321
C+ G F C N+ I S+ DG DC DG DE++ NCT
Sbjct: 3100 CNKGEFRCSNQ----HCIHSTWECDGDNDCLDGSDEHA---NCT 3136
Score = 31.2 bits (69), Expect = 3.4
Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 9/60 (15%)
Frame = +1
Query: 151 DCRDATDEPGTSACSNG---------VFHCDNKGHKSQLIPSSRVNDGICDCCDGQDEYS 303
DC D DE T+ +F CDN + I + + DG DC DG DE+S
Sbjct: 2985 DCSDGWDETHTNCTDTAGKKICVGDYLFQCDNL----KCISRAFICDGEDDCGDGSDEHS 3040
Score = 30.4 bits (67), Expect = 5.8
Identities = 31/97 (31%), Positives = 38/97 (39%), Gaps = 17/97 (17%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEPGTSACSNGVFHCD---NKGHKSQLIPSSRVN 261
FKC +G +N D DC DA+DE G S G C+ N G + + V
Sbjct: 4054 FKCANGK-CVNGTVACDRKDDCGDASDEIGCSK-HGGKTSCEAFGNNGGCKHI--CTDVR 4109
Query: 262 DGI-CDCCDG-------------QDEYSGIINCTNTC 330
DG C C DG DE +G CT C
Sbjct: 4110 DGFYCHCRDGFRPDPQSPKECIDIDECAGNNTCTQLC 4146
>sp|P34576|MUA3_CAEEL Transmembrane cell adhesion receptor mua-3 precursor
Length = 3767
Score = 44.7 bits (104), Expect = 3e-04
Identities = 25/69 (36%), Positives = 34/69 (49%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEPGTSACSNGVFHCDNKGHKSQLIPSSRVNDGI 270
F C D S I K + DC+D +DEP C+ F C + ++ IP ++ DG
Sbjct: 102 FVCRDRSACIEPSKYLNGVADCKDKSDEP----CAQNQFQCSD---GTKCIPKAQFQDGK 154
Query: 271 CDCCDGQDE 297
DC DG DE
Sbjct: 155 EDCDDGSDE 163
Score = 39.7 bits (91), Expect = 0.010
Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 6/83 (7%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEPGTS---ACSNGVFHCDNKGHKSQLIPSSRVN 261
F+C DG+ I + D DC D +DE T+ AC G C + + +
Sbjct: 136 FQCSDGTKCIPKAQFQDGKEDCDDGSDEECTTSQFACQCGTIKC---------VSDTFIM 186
Query: 262 DGICDCCDGQDEYSG---IINCT 321
DG DC DG DE+ NCT
Sbjct: 187 DGNWDCEDGSDEFINKTLTANCT 209
>sp|P98164|LRP2_HUMAN Low-density lipoprotein receptor-related protein 2 precursor
(Megalin) (Glycoprotein 330) (gp330)
Length = 4655
Score = 44.7 bits (104), Expect = 3e-04
Identities = 27/70 (38%), Positives = 34/70 (48%), Gaps = 3/70 (4%)
Frame = +1
Query: 121 NWMKVNDDYCDCRDATDEPG---TSACSNGVFHCDNKGHKSQLIPSSRVNDGICDCCDGQ 291
NW+ D+ DC D +DE T C F+C N + I S V DG DC DG
Sbjct: 1125 NWVCDTDN--DCGDGSDEKNCNSTETCQPSQFNCPNH----RCIDLSFVCDGDKDCVDGS 1178
Query: 292 DEYSGIINCT 321
DE ++NCT
Sbjct: 1179 DEVGCVLNCT 1188
Score = 41.6 bits (96), Expect = 0.003
Identities = 30/72 (41%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Frame = +1
Query: 91 FKCLDGSGI-INWMKVNDDYCDCRDATDEPGTSA--CSNGVFHCDNKGHKSQLIPSSRVN 261
F+C G I +W D DC D DE G + C G F C ++G Q IPSS V
Sbjct: 33 FRCGSGHCIPADWRC--DGTKDCSDDADEIGCAVVTCQQGYFKCQSEG---QCIPSSWVC 87
Query: 262 DGICDCCDGQDE 297
D DC DG DE
Sbjct: 88 DQDQDCDDGSDE 99
Score = 41.2 bits (95), Expect = 0.003
Identities = 35/89 (39%), Positives = 40/89 (44%), Gaps = 7/89 (7%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEP-----GTSACSNGVFHCDN-KGHKSQLIPSS 252
FKC DG I + D DC D +DE CS+ F C N + + IP S
Sbjct: 2911 FKC-DGGRCIPSEWICDGDNDCGDMSDEDKRHQCQNQNCSDSEFLCVNDRPPDRRCIPQS 2969
Query: 253 RVNDGICDCCDGQDEYSGIINCT-NTCWE 336
V DG DC DG DE NCT TC E
Sbjct: 2970 WVCDGDVDCTDGYDENQ---NCTRRTCSE 2995
Score = 38.1 bits (87), Expect = 0.028
Identities = 24/68 (35%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Frame = +1
Query: 103 DGSGIINWMKVNDDYCDCRDATDEPG-TSACSNGVFHCDNKGHKSQLIPSSRVNDGICDC 279
D N + D DCRD++DE T C + F C N + IP + V D DC
Sbjct: 153 DNGACYNTSQKCDWKVDCRDSSDEINCTEICLHNEFSCGN----GECIPRAYVCDHDNDC 208
Query: 280 CDGQDEYS 303
DG DE++
Sbjct: 209 QDGSDEHA 216
Score = 37.4 bits (85), Expect = 0.048
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Frame = +1
Query: 127 MKVNDDYCDCR-DATDEPGTSACSNGVFHCDNKGHKSQLIPSSRVNDGICDCCDGQDE-Y 300
M++ ++ C D T+EP T C F C N + +P+ + DG+ DC D DE
Sbjct: 1004 MRLASNHLTCEGDPTNEPPTEQCGLFSFPCKN----GRCVPNYYLCDGVDDCHDNSDEQL 1059
Query: 301 SGIINCTNTC 330
G +N NTC
Sbjct: 1060 CGTLN--NTC 1067
Score = 37.4 bits (85), Expect = 0.048
Identities = 33/108 (30%), Positives = 49/108 (45%), Gaps = 4/108 (3%)
Frame = +1
Query: 19 HITCIEKPRGVPFSKLSFYQPNTPFKCLDGSGIINWMKVNDDYCDCRDATDEP--GT--S 186
H+TC P P ++ F C +G + N+ + D DC D +DE GT +
Sbjct: 1010 HLTCEGDPTNEPPTEQCGL---FSFPCKNGRCVPNYY-LCDGVDDCHDNSDEQLCGTLNN 1065
Query: 187 ACSNGVFHCDNKGHKSQLIPSSRVNDGICDCCDGQDEYSGIINCTNTC 330
CS+ F C GH + IP+ D DC DG DE++ + +C
Sbjct: 1066 TCSSSAFTC---GH-GECIPAHWRCDKRNDCVDGSDEHNCPTHAPASC 1109
Score = 37.0 bits (84), Expect = 0.062
Identities = 27/72 (37%), Positives = 30/72 (41%), Gaps = 3/72 (4%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEP---GTSACSNGVFHCDNKGHKSQLIPSSRVN 261
FKC I V D DC D +DE S CS+ C N Q IPS
Sbjct: 72 FKCQSEGQCIPSSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSN----GQCIPSEYRC 127
Query: 262 DGICDCCDGQDE 297
D + DC DG DE
Sbjct: 128 DHVRDCPDGADE 139
Score = 37.0 bits (84), Expect = 0.062
Identities = 25/79 (31%), Positives = 31/79 (39%), Gaps = 5/79 (6%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDEPG-----TSACSNGVFHCDNKGHKSQLIPSSR 255
FKC G I D DC D +DE G C + F C G IP+
Sbjct: 1192 FKCASGDKCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQCQEDG---ICIPNFW 1248
Query: 256 VNDGICDCCDGQDEYSGII 312
DG DC G DE++ +
Sbjct: 1249 ECDGHPDCLYGSDEHNACV 1267
Score = 35.8 bits (81), Expect = 0.14
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 6/78 (7%)
Frame = +1
Query: 82 NTPFKCLDGSGII-NWMKVNDDYCDCRDATDEPGTSA-----CSNGVFHCDNKGHKSQLI 243
++ F+C G I +W D DC DA+DEP + C F CD + I
Sbjct: 2866 SSEFQCASGRCIPQHWYC--DQETDCFDASDEPASCGHSERTCLADEFKCDG----GRCI 2919
Query: 244 PSSRVNDGICDCCDGQDE 297
PS + DG DC D DE
Sbjct: 2920 PSEWICDGDNDCGDMSDE 2937
Score = 35.4 bits (80), Expect = 0.18
Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Frame = +1
Query: 91 FKCLDGSGIINWMKVNDDYCDCRDATDE-------PGTSACSNGVFHCDNKGHKSQLIPS 249
F+C G + + +K D DC DA+DE P + C +F C N IP
Sbjct: 3803 FQCTSGHCVHSELKC-DGSADCLDASDEADCPTRFPDGAYCQATMFECKNH----VCIPP 3857
Query: 250 SRVNDGICDCCDGQDE 297
DG DC DG DE
Sbjct: 3858 YWKCDGDDDCGDGSDE 3873
Score = 33.1 bits (74), Expect = 0.90
Identities = 31/94 (32%), Positives = 38/94 (40%), Gaps = 9/94 (9%)
Frame = +1
Query: 82 NTP--FKCLDGSGIINWMKVNDDYCDCRDATDE-------PGTSACSNGVFHCDNKGHKS 234
N+P F+C D + I +V + DC D TDE P C+ + C N GH
Sbjct: 3884 NSPNRFRC-DNNRCIYSHEVCNGVDDCGDGTDETEEHCRKPTPKPCTEYEYKCGN-GH-- 3939
Query: 235 QLIPSSRVNDGICDCCDGQDEYSGIINCTNTCWE 336
IP V D DC D DE TC E
Sbjct: 3940 -CIPHDNVCDDADDCGDWSDELGCNKGKERTCAE 3972
Score = 32.0 bits (71), Expect = 2.0
Identities = 20/55 (36%), Positives = 25/55 (45%), Gaps = 2/55 (3%)
Frame = +1
Query: 139 DDYCDCRDATDEPGTSA--CSNGVFHCDNKGHKSQLIPSSRVNDGICDCCDGQDE 297
D DC D +DE + C+ F C N+ Q IPS + D DC D DE
Sbjct: 3740 DGQNDCGDNSDEENCApreCTESEFRCVNQ----QCIPSRWICDHYNDCGDNSDE 3790
Score = 30.4 bits (67), Expect = 5.8
Identities = 24/83 (28%), Positives = 34/83 (40%), Gaps = 4/83 (4%)
Frame = +1
Query: 94 KCLDGSGIINWMKVNDDYCDCRDATDEP----GTSACSNGVFHCDNKGHKSQLIPSSRVN 261
KC + + I + + D DC D +DE T CS+ F C + + IP
Sbjct: 2828 KCHNSNICIPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCAS----GRCIPQHWYC 2883
Query: 262 DGICDCCDGQDEYSGIINCTNTC 330
D DC D DE + + TC
Sbjct: 2884 DQETDCFDASDEPASCGHSERTC 2906
Score = 30.4 bits (67), Expect = 5.8
Identities = 26/74 (35%), Positives = 28/74 (37%), Gaps = 3/74 (4%)
Frame = +1
Query: 85 TPFKCLDGSGIINWMKVNDDYCDCRDATDEPGTS--ACSN-GVFHCDNKGHKSQLIPSSR 255
T F C I V + DCRD +DE G C G F C N IP
Sbjct: 3682 TEFSCKTNYRCIPKWAVCNGVDDCRDNSDEQGCEERTCHPVGDFRCKN----HHCIPLRW 3737
Query: 256 VNDGICDCCDGQDE 297
DG DC D DE
Sbjct: 3738 QCDGQNDCGDNSDE 3751
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,684,145
Number of Sequences: 369166
Number of extensions: 1405755
Number of successful extensions: 6124
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5166
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5888
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7522142940
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)