Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_E14
(625 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P49900|ARGI_RANCA Arginase, hepatic 94 2e-19
sp|P05089|ARGI1_HUMAN Arginase-1 (Type I arginase) (Liver-t... 86 8e-17
sp|Q95KM0|ARGI1_RABIT Arginase-1 (Type I arginase) (Liver-t... 85 2e-16
sp|Q95JC8|ARGI1_PIG Arginase-1 (Type I arginase) (Liver-typ... 84 2e-16
sp|P07824|ARGI1_RAT Arginase-1 (Type I arginase) (Liver-typ... 84 4e-16
sp|Q61176|ARGI1_MOUSE Arginase-1 (Type I arginase) (Liver-t... 82 1e-15
sp|P30759|ARGI1_XENLA Arginase-1 (Type I arginase) (Arginas... 77 5e-14
sp|Q91553|ARGN1_XENLA Arginase, non-hepatic 1 75 1e-13
sp|Q91554|ARGN2_XENLA Arginase, non-hepatic 2 75 1e-13
sp|Q91555|ARGN3_XENLA Arginase, non-hepatic 3 74 2e-13
>sp|P49900|ARGI_RANCA Arginase, hepatic
Length = 323
Score = 94.4 bits (233), Expect = 2e-19
Identities = 54/191 (28%), Positives = 101/191 (52%)
Frame = +2
Query: 53 RKIGIVGVPVESGHKLSG*KDSPNFIRGNDLIEKILKLCYVVSDYGNIEPLEVNDDYKAY 232
R +G++G P G G ++ P +IR LIEK+ +L Y V DYG++ E+ D
Sbjct: 7 RSVGVLGAPFSKGQARGGVEEGPIYIRRAGLIEKLEELEYEVRDYGDLHFPELPCDEPFQ 66
Query: 233 NAISPKTFILNTSHTKTEVAQPLYQYDSVLVLGGDTTVCTVSILCHWRIYTDVCIIFVGR 412
N +P+T V++ L LGGD ++ +I H +++ D+C+++V
Sbjct: 67 NVKNPRTVGQAAEKVANAVSEVKRSGRVCLTLGGDHSLAVGTITGHAKVHPDLCVVWVDA 126
Query: 413 KPGLHTLLCSTSGDMNDMPLFLILSYMHTEILSINDFRKLLPIIFSKNIVFFVLHEVDIF 592
++T + S SG+++ P+ ++ + T++ +I F + P + +K+IV+ L +VD
Sbjct: 127 HADINTPITSPSGNLHGQPVSFLIRELQTKVPAIPGFSWVQPSLSAKDIVYIGLRDVDPG 186
Query: 593 KTYMINTHIIK 625
+ Y++ T IK
Sbjct: 187 EHYILKTLGIK 197
>sp|P05089|ARGI1_HUMAN Arginase-1 (Type I arginase) (Liver-type arginase)
Length = 322
Score = 85.9 bits (211), Expect = 8e-17
Identities = 55/191 (28%), Positives = 99/191 (51%)
Frame = +2
Query: 53 RKIGIVGVPVESGHKLSG*KDSPNFIRGNDLIEKILKLCYVVSDYGNIEPLEVNDDYKAY 232
R IGI+G P G G ++ P +R L+EK+ + V DYG++ ++ +D
Sbjct: 6 RTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQ 65
Query: 233 NAISPKTFILNTSHTKTEVAQPLYQYDSVLVLGGDTTVCTVSILCHWRIYTDVCIIFVGR 412
+P++ + +VA+ LVLGGD ++ SI H R++ D+ +I+V
Sbjct: 66 IVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDA 125
Query: 413 KPGLHTLLCSTSGDMNDMPLFLILSYMHTEILSINDFRKLLPIIFSKNIVFFVLHEVDIF 592
++T L +TSG+++ P+ +L + +I + F + P I +K+IV+ L +VD
Sbjct: 126 HTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPG 185
Query: 593 KTYMINTHIIK 625
+ Y++ T IK
Sbjct: 186 EHYILKTLGIK 196
>sp|Q95KM0|ARGI1_RABIT Arginase-1 (Type I arginase) (Liver-type arginase)
Length = 322
Score = 84.7 bits (208), Expect = 2e-16
Identities = 54/191 (28%), Positives = 97/191 (50%)
Frame = +2
Query: 53 RKIGIVGVPVESGHKLSG*KDSPNFIRGNDLIEKILKLCYVVSDYGNIEPLEVNDDYKAY 232
+ IGI+G P G G ++ P +R L+EK+ + + V+DYG++ +V +D +
Sbjct: 6 KSIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQEHDVTDYGDLSFADVPNDSPFH 65
Query: 233 NAISPKTFILNTSHTKTEVAQPLYQYDSVLVLGGDTTVCTVSILCHWRIYTDVCIIFVGR 412
+P+ VA+ LVLGGD ++ SI H + D+ +I+V
Sbjct: 66 IVKNPRAVGRANEQLAGAVAEIKKNGRISLVLGGDHSLAIGSISGHASVCPDLAVIWVDA 125
Query: 413 KPGLHTLLCSTSGDMNDMPLFLILSYMHTEILSINDFRKLLPIIFSKNIVFFVLHEVDIF 592
++T L +TSG+++ P+ +L + +I + F + P I +K+IV+ L +VD
Sbjct: 126 HTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPG 185
Query: 593 KTYMINTHIIK 625
+ Y++ T IK
Sbjct: 186 EHYIVKTLGIK 196
>sp|Q95JC8|ARGI1_PIG Arginase-1 (Type I arginase) (Liver-type arginase)
Length = 322
Score = 84.3 bits (207), Expect = 2e-16
Identities = 53/191 (27%), Positives = 98/191 (51%)
Frame = +2
Query: 53 RKIGIVGVPVESGHKLSG*KDSPNFIRGNDLIEKILKLCYVVSDYGNIEPLEVNDDYKAY 232
+ IGI+G P G G ++ P +R L+EK+ + V DYG++ +V +D
Sbjct: 6 QSIGIIGAPFSKGQPRGGVEEGPTALRKAGLLEKLKEQECDVKDYGDLCFADVPNDTPFQ 65
Query: 233 NAISPKTFILNTSHTKTEVAQPLYQYDSVLVLGGDTTVCTVSILCHWRIYTDVCIIFVGR 412
+P++ VA+ + LVLGGD ++ SI H R++ D+C+I+V
Sbjct: 66 IVKNPRSVGKANQQLADVVAEIKKNGRTSLVLGGDHSMAIGSISGHARVHPDLCVIWVDA 125
Query: 413 KPGLHTLLCSTSGDMNDMPLFLILSYMHTEILSINDFRKLLPIIFSKNIVFFVLHEVDIF 592
++T L +T+G+++ P+ +L + +I + + P + +K+IV+ L +VD
Sbjct: 126 HTDINTPLTTTTGNLHGQPVSFLLKELKEKIPEVPGLSWVTPCLSAKDIVYIGLRDVDPA 185
Query: 593 KTYMINTHIIK 625
+ Y++ T IK
Sbjct: 186 EHYILKTLGIK 196
>sp|P07824|ARGI1_RAT Arginase-1 (Type I arginase) (Liver-type arginase)
Length = 323
Score = 83.6 bits (205), Expect = 4e-16
Identities = 53/191 (27%), Positives = 97/191 (50%)
Frame = +2
Query: 53 RKIGIVGVPVESGHKLSG*KDSPNFIRGNDLIEKILKLCYVVSDYGNIEPLEVNDDYKAY 232
+ I I+G P G G + P +R L+EK+ + Y V D+G++ ++V +D
Sbjct: 6 KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQ 65
Query: 233 NAISPKTFILNTSHTKTEVAQPLYQYDSVLVLGGDTTVCTVSILCHWRIYTDVCIIFVGR 412
+P++ VA+ +VLGGD ++ SI H R++ D+C+I+V
Sbjct: 66 IVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDA 125
Query: 413 KPGLHTLLCSTSGDMNDMPLFLILSYMHTEILSINDFRKLLPIIFSKNIVFFVLHEVDIF 592
++T L ++SG+++ P+ +L + + + F + P I +K+IV+ L +VD
Sbjct: 126 HTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPG 185
Query: 593 KTYMINTHIIK 625
+ Y+I T IK
Sbjct: 186 EHYIIKTLGIK 196
>sp|Q61176|ARGI1_MOUSE Arginase-1 (Type I arginase) (Liver-type arginase)
Length = 323
Score = 82.0 bits (201), Expect = 1e-15
Identities = 52/191 (27%), Positives = 97/191 (50%)
Frame = +2
Query: 53 RKIGIVGVPVESGHKLSG*KDSPNFIRGNDLIEKILKLCYVVSDYGNIEPLEVNDDYKAY 232
+ + I+G P G G + P +R L+EK+ + Y V D+G++ ++V +D
Sbjct: 6 KSLEIIGAPFSKGQPRGGVEKGPAALRKAGLLEKLKETEYDVRDHGDLAFVDVPNDSSFQ 65
Query: 233 NAISPKTFILNTSHTKTEVAQPLYQYDSVLVLGGDTTVCTVSILCHWRIYTDVCIIFVGR 412
+P++ VA+ +VLGGD ++ SI H R++ D+C+I+V
Sbjct: 66 IVKNPRSVGKANEELAGVVAEVQKNGRVSVVLGGDHSLAVGSISGHARVHPDLCVIWVDA 125
Query: 413 KPGLHTLLCSTSGDMNDMPLFLILSYMHTEILSINDFRKLLPIIFSKNIVFFVLHEVDIF 592
++T L ++SG+++ P+ +L + + + F + P I +K+IV+ L +VD
Sbjct: 126 HTDINTPLTTSSGNLHGQPVSFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPG 185
Query: 593 KTYMINTHIIK 625
+ Y+I T IK
Sbjct: 186 EHYIIKTLGIK 196
>sp|P30759|ARGI1_XENLA Arginase-1 (Type I arginase) (Arginase, hepatic)
Length = 316
Score = 76.6 bits (187), Expect = 5e-14
Identities = 46/189 (24%), Positives = 94/189 (49%)
Frame = +2
Query: 59 IGIVGVPVESGHKLSG*KDSPNFIRGNDLIEKILKLCYVVSDYGNIEPLEVNDDYKAYNA 238
+G++G P G G ++ P ++R LIEK+ + V D G+++ +V +D N
Sbjct: 8 VGVIGAPFSKGQPRRGVEEGPKYLREAGLIEKLREFGNDVRDCGDLDFPDVPNDTPFNNV 67
Query: 239 ISPKTFILNTSHTKTEVAQPLYQYDSVLVLGGDTTVCTVSILCHWRIYTDVCIIFVGRKP 418
+P+T T V + +GGD ++ +I H ++ ++C+++V
Sbjct: 68 KNPRTVGKATEILANAVTAVKKADKTCQSIGGDHSLAVGTIAGHAAVHPNLCVVWVDAHA 127
Query: 419 GLHTLLCSTSGDMNDMPLFLILSYMHTEILSINDFRKLLPIIFSKNIVFFVLHEVDIFKT 598
++T S G+++ PL ++ + ++ ++ F + P + SK+IV+ L +VD +
Sbjct: 128 DINTPSTSPCGNLHGQPLSFLMKELKAKMPAVPGFEWVKPCLRSKDIVYIGLRDVDPGEH 187
Query: 599 YMINTHIIK 625
Y++ T IK
Sbjct: 188 YILKTLGIK 196
>sp|Q91553|ARGN1_XENLA Arginase, non-hepatic 1
Length = 360
Score = 75.5 bits (184), Expect = 1e-13
Identities = 50/190 (26%), Positives = 96/190 (50%), Gaps = 2/190 (1%)
Frame = +2
Query: 59 IGIVGVPVESGHKLSG*KDSPNFIRGNDLIEKILKLCYVVSDYGNIEPLEVNDDYKAYNA 238
+ ++G P G K G + P IR LIE++ L V D+G++ +V +D + YN+
Sbjct: 28 VAVIGAPFSKGQKRRGVEHGPAAIRSAGLIERLSNLGCNVCDFGDLHFSQVPND-ELYNS 86
Query: 239 I--SPKTFILNTSHTKTEVAQPLYQYDSVLVLGGDTTVCTVSILCHWRIYTDVCIIFVGR 412
I P+T L EV++ + + + LGGD ++ SI H + D+C+I+V
Sbjct: 87 IVKHPRTVGLACKVLAEEVSKAVGAGHTCVTLGGDHSLAFGSITGHAQQCPDLCVIWVDA 146
Query: 413 KPGLHTLLCSTSGDMNDMPLFLILSYMHTEILSINDFRKLLPIIFSKNIVFFVLHEVDIF 592
++T L + SG+++ P+ +L + ++ I F P + +IV+ L ++D
Sbjct: 147 HADINTPLTTPSGNLHGQPVSFLLRELQDKVPPIPGFSWAKPCLSKSDIVYIGLRDLDPA 206
Query: 593 KTYMINTHII 622
+ +++ + I
Sbjct: 207 EQFILKNYDI 216
>sp|Q91554|ARGN2_XENLA Arginase, non-hepatic 2
Length = 360
Score = 75.1 bits (183), Expect = 1e-13
Identities = 50/190 (26%), Positives = 96/190 (50%), Gaps = 2/190 (1%)
Frame = +2
Query: 59 IGIVGVPVESGHKLSG*KDSPNFIRGNDLIEKILKLCYVVSDYGNIEPLEVNDDYKAYNA 238
+ ++G P G K G + P IR LIE++ L V D+G++ +V +D + YN+
Sbjct: 28 VAVIGAPFSKGQKRRGVEHGPAAIRSAGLIERLSNLGCNVCDFGDLHFSKVPND-ELYNS 86
Query: 239 I--SPKTFILNTSHTKTEVAQPLYQYDSVLVLGGDTTVCTVSILCHWRIYTDVCIIFVGR 412
I P+T L EV++ + + + LGGD ++ SI H + D+C+I+V
Sbjct: 87 IVKHPRTVGLACKVLAEEVSKAVGAGHTCVTLGGDHSLAFGSITGHAQQCPDLCVIWVDA 146
Query: 413 KPGLHTLLCSTSGDMNDMPLFLILSYMHTEILSINDFRKLLPIIFSKNIVFFVLHEVDIF 592
++T L + SG+++ P+ +L + ++ I F P + +IV+ L ++D
Sbjct: 147 HADINTPLTTPSGNLHGQPVSFLLRELQDKVPPIPGFSWAKPCLSKSDIVYIGLRDLDPA 206
Query: 593 KTYMINTHII 622
+ +++ + I
Sbjct: 207 EQFILKNYNI 216
>sp|Q91555|ARGN3_XENLA Arginase, non-hepatic 3
Length = 360
Score = 74.3 bits (181), Expect = 2e-13
Identities = 50/190 (26%), Positives = 95/190 (50%), Gaps = 2/190 (1%)
Frame = +2
Query: 59 IGIVGVPVESGHKLSG*KDSPNFIRGNDLIEKILKLCYVVSDYGNIEPLEVNDDYKAYNA 238
+ ++G P G K G + P IR LI+++ L V D+G++ +V +D + YN+
Sbjct: 28 VAVIGAPFSKGQKRRGVEHGPAAIRSAGLIDRLSNLGCNVCDFGDLHFSQVPND-EQYNS 86
Query: 239 I--SPKTFILNTSHTKTEVAQPLYQYDSVLVLGGDTTVCTVSILCHWRIYTDVCIIFVGR 412
I P+T L EV + + + + LGGD ++ SI H + D+C+I+V
Sbjct: 87 IVKHPRTVGLACKVLAKEVGKAVGAGHTCVTLGGDHSLAFGSITGHAQQCPDLCVIWVDA 146
Query: 413 KPGLHTLLCSTSGDMNDMPLFLILSYMHTEILSINDFRKLLPIIFSKNIVFFVLHEVDIF 592
++T L + SG+++ P+ +L + +I I F P + +IV+ L ++D
Sbjct: 147 HADINTPLTTPSGNLHGQPVSFLLRELQDKIPPIPGFSWAKPCLSKSDIVYIGLRDLDPA 206
Query: 593 KTYMINTHII 622
+ +++ + I
Sbjct: 207 EQFILKNYNI 216
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,950,171
Number of Sequences: 369166
Number of extensions: 1598692
Number of successful extensions: 3801
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3680
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3784
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 4926080070
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)