Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_D24
(855 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P19179|FIMB_CHICK Fimbrin 192 1e-48
sp|Q14651|PLSI_HUMAN I-plastin (Intestine-specific plastin)... 191 2e-48
sp|P13796|PLSL_HUMAN L-plastin (Lymphocyte cytosolic protei... 189 1e-47
sp|Q61233|PLSL_MOUSE L-plastin (Lymphocyte cytosolic protei... 187 3e-47
sp|Q63598|PLST_RAT T-plastin (Plastin-3) 186 7e-47
sp|Q99K51|PLST_MOUSE T-plastin (Plastin-3) 185 1e-46
sp|O88818|PLST_CRIGR T-plastin (Plastin-3) 185 2e-46
sp|P13797|PLST_HUMAN T-plastin (Plastin-3) 183 6e-46
sp|Q6P698|PLSL_BRARE L-plastin (Lymphocyte cytosolic plasti... 182 1e-45
sp|P54680|FIMB_DICDI Fimbrin 172 8e-43
>sp|P19179|FIMB_CHICK Fimbrin
Length = 630
Score = 192 bits (488), Expect = 1e-48
Identities = 120/301 (39%), Positives = 171/301 (56%), Gaps = 20/301 (6%)
Frame = +3
Query: 12 DNMKRAELMLGNASLIDARVFIEPEDVALVTQRGQNREKLNLAFVANLFNTYPALIVDSX 191
++++RAE ML A + R F+ P DV KLNLAFVANLFNTYPAL
Sbjct: 331 NDLRRAECMLQQADKLGCRQFVTPADVVA------GNPKLNLAFVANLFNTYPALHKPDN 384
Query: 192 XXXXXXXXXX-----KTYRNWINSMGVTPYVKDLYSDXXXXXXXXXXXXXXQPGIVEWKK 356
+T+RNW+NS+GV+PYV LYSD + V+W
Sbjct: 385 SSYDLTLLEGESNEERTFRNWMNSLGVSPYVNHLYSDLSDALIIFQLYEMTRVP-VDWTH 443
Query: 357 IVRVFDPKKKIFQVLG-------NCAHVIECAK-KLQLSIVNLSADNIKDATPNLTLGLC 512
+ K+ + +LG NC + +E K K + S+V ++ ++ + P LTL L
Sbjct: 444 V------NKRPYPLLGGNMKKIENCNYAVELGKTKAKFSLVGIAGHDLNEGNPTLTLALI 497
Query: 513 FQMLRCYTMKLLSKVLPGKK-DDKDIVAWANGKLEAANKTSKITGFRDQSIATSKPVLDL 689
+Q++R YT+ +LS + G+K +D+ I+ W N L ANK + IT F+D+SI+TS PVLDL
Sbjct: 498 WQLMRRYTLNVLSDLGEGEKVNDEIIIKWVNQTLANANKKTSITSFKDKSISTSLPVLDL 557
Query: 690 IDSIVPNSVDYKLLTGE------PLQDAKFAISQARRIGARIYALPQHLVDVNQKMVMTI 851
ID+I P +V +++ E L +AK+AIS AR+IGARIYALP LV+V KMVMT+
Sbjct: 558 IDAIAPKAVRQEMVKREDLSYQDKLNNAKYAISVARKIGARIYALPDDLVEVKPKMVMTV 617
Query: 852 Y 854
+
Sbjct: 618 F 618
Score = 42.0 bits (97), Expect = 0.002
Identities = 42/183 (22%), Positives = 81/183 (44%), Gaps = 29/183 (15%)
Frame = +3
Query: 378 KKKI--FQVLGNCAHVIECAKKLQLSIVNLSADNIKDATPNLTLGLCFQMLR-------- 527
KKK+ F + N + A + ++VN+ + ++++ P+L LGL +Q+++
Sbjct: 184 KKKLTPFTISENLNLALNSASAIGCTVVNIGSQDLQEGKPHLVLGLLWQIIKVGLFADIE 243
Query: 528 -CYTMKLLSKVLPGKKDD--------KDIVAWANGKLEAANKTSKITGFRDQSIATSKPV 680
L++ + G++ D + ++ W N L A KI+ F Q I S+
Sbjct: 244 ISRNEALIALLNEGEELDQLMKLSPEELLLRWVNYHLANAG-WQKISNF-SQDIRDSRAY 301
Query: 681 LDLIDSIVPNSVDYKLLTGE----------PLQDAKFAISQARRIGARIYALPQHLVDVN 830
L++ I P D+ + E L+ A+ + QA ++G R + P +V N
Sbjct: 302 YHLLNQIAPKGDDFDEIHVEIDFSGFNDKNDLRRAECMLQQADKLGCRQFVTPADVVAGN 361
Query: 831 QKM 839
K+
Sbjct: 362 PKL 364
>sp|Q14651|PLSI_HUMAN I-plastin (Intestine-specific plastin) (Plastin-1)
Length = 629
Score = 191 bits (486), Expect = 2e-48
Identities = 119/302 (39%), Positives = 170/302 (56%), Gaps = 20/302 (6%)
Frame = +3
Query: 9 TDNMKRAELMLGNASLIDARVFIEPEDVALVTQRGQNREKLNLAFVANLFNTYPALIVDS 188
T+++KRA LML A + + F+ P DV KLNLAFVANLFNTYP L +
Sbjct: 329 TNDLKRAGLMLQEADKLGCKQFVTPADVV------SGNPKLNLAFVANLFNTYPCLHKPN 382
Query: 189 XXXXXXXXXXX-----KTYRNWINSMGVTPYVKDLYSDXXXXXXXXXXXXXXQPGIVEWK 353
+T+RNW+NS+GV PY+ LYSD + V W
Sbjct: 383 NNDIDMNLLEGESKEERTFRNWMNSLGVNPYINHLYSDLADALVIFQLYEMIRVP-VNWS 441
Query: 354 KIVRVFDPKKKIFQVLG-------NCAHVIECAK-KLQLSIVNLSADNIKDATPNLTLGL 509
+ K + LG NC + +E K K + S+V ++ ++ + LTL L
Sbjct: 442 HV------NKPPYPALGGNMKKIENCNYAVELGKNKAKFSLVGIAGQDLNERNSTLTLAL 495
Query: 510 CFQMLRCYTMKLLSKVLPGKK-DDKDIVAWANGKLEAANKTSKITGFRDQSIATSKPVLD 686
+Q++R YT+ +LS + G+K +D+ I+ W N L++ANK + I+ F+D+SI+TS PVLD
Sbjct: 496 VWQLMRRYTLNVLSDLGEGEKVNDEIIIKWVNQTLKSANKKTSISSFKDKSISTSLPVLD 555
Query: 687 LIDSIVPNSVDYKLLTGEPLQD------AKFAISQARRIGARIYALPQHLVDVNQKMVMT 848
LID+I PN+V +++ E L D AK+AIS AR+IGARIYALP LV+V KMVMT
Sbjct: 556 LIDAIAPNAVRQEMIRRENLSDEDKLNNAKYAISVARKIGARIYALPDDLVEVKPKMVMT 615
Query: 849 IY 854
++
Sbjct: 616 VF 617
Score = 36.6 bits (83), Expect = 0.091
Identities = 39/182 (21%), Positives = 79/182 (43%), Gaps = 28/182 (15%)
Frame = +3
Query: 378 KKKI--FQVLGNCAHVIECAKKLQLSIVNLSADNIKDATPNLTLGLCFQMLR-------- 527
KKK+ F + N + A + ++VN+ A ++K+ P+L LGL +Q+++
Sbjct: 184 KKKLTPFTISENLNLALNSASAIGCTVVNIGASDLKEGKPHLVLGLLWQIIKVGLFADIE 243
Query: 528 -CYTMKLLSKVLPGKK--------DDKDIVAWANGKLEAANKTSKITGFRDQSIATSKPV 680
L++ + G++ ++ ++ W N L A I+ F Q I S+
Sbjct: 244 ISRNEALIALLNEGEELEELMKLSPEELLLRWVNYHLTNAG-WHTISNF-SQDIKDSRAY 301
Query: 681 LDLIDSIVPN--------SVDYK-LLTGEPLQDAKFAISQARRIGARIYALPQHLVDVNQ 833
L++ I P ++D + L+ A + +A ++G + + P +V N
Sbjct: 302 FHLLNQIAPKGGEDGPAIAIDLSGINETNDLKRAGLMLQEADKLGCKQFVTPADVVSGNP 361
Query: 834 KM 839
K+
Sbjct: 362 KL 363
>sp|P13796|PLSL_HUMAN L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P)
Length = 627
Score = 189 bits (479), Expect = 1e-47
Identities = 116/298 (38%), Positives = 167/298 (56%), Gaps = 14/298 (4%)
Frame = +3
Query: 3 KNTDNMKRAELMLGNASLIDARVFIEPEDVALVTQRGQNREKLNLAFVANLFNTYPALIV 182
+ D+++RAE ML A + R F+ DV + KLNLAF+ANLFN YPAL
Sbjct: 326 REKDDIQRAECMLQQAERLGCRQFVTATDVV------RGNPKLNLAFIANLFNRYPALHK 379
Query: 183 DSXXXXXXXXXXX-----KTYRNWINSMGVTPYVKDLYSDXXXXXXXXXXXXXXQPGIVE 347
+T+RNW+NS+GV P V LYSD + V+
Sbjct: 380 PENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIKVP-VD 438
Query: 348 WKKIVRVFDPKKK-IFQVLGNCAHVIECAK-KLQLSIVNLSADNIKDATPNLTLGLCFQM 521
W ++ + PK + L NC + +E K + + S+V + ++ + LTL L +Q+
Sbjct: 439 WNRVNKPPYPKLGGNMKKLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQL 498
Query: 522 LRCYTMKLLSKVLPGKKDDKDIVA-WANGKLEAANKTSKITGFRDQSIATSKPVLDLIDS 698
+R YT+ +L ++ G+K + DI+ W N L A K+S I+ F+D I+TS PVLDLID+
Sbjct: 499 MRRYTLNILEEIGGGQKVNDDIIVNWVNETLREAEKSSSISSFKDPKISTSLPVLDLIDA 558
Query: 699 IVPNSVDYKLLTGEPLQD------AKFAISQARRIGARIYALPQHLVDVNQKMVMTIY 854
I P S++Y LL E L D AK+AIS AR+IGAR+YALP+ LV+VN KMVMT++
Sbjct: 559 IQPGSINYDLLKTENLNDDEKLNNAKYAISMARKIGARVYALPEDLVEVNPKMVMTVF 616
Score = 42.7 bits (99), Expect = 0.001
Identities = 44/183 (24%), Positives = 79/183 (43%), Gaps = 29/183 (15%)
Frame = +3
Query: 378 KKKI--FQVLGNCAHVIECAKKLQLSIVNLSADNIKDATPNLTLGLCFQMLR-------- 527
KKK+ F + N + A + +VN+ A+++K+ P L LGL +Q+++
Sbjct: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIE 241
Query: 528 -CYTMKLLSKVLPGK--------KDDKDIVAWANGKLEAANKTSKITGFRDQSIATSKPV 680
L++ + G+ ++ ++ WAN LE A +KI F I SK
Sbjct: 242 LSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAG-CNKIGNF-STDIKDSKAY 299
Query: 681 LDLIDSIVPNS---------VDYK-LLTGEPLQDAKFAISQARRIGARIYALPQHLVDVN 830
L++ + P +D L + +Q A+ + QA R+G R + +V N
Sbjct: 300 YHLLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGN 359
Query: 831 QKM 839
K+
Sbjct: 360 PKL 362
>sp|Q61233|PLSL_MOUSE L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage
protein) (pp65)
Length = 627
Score = 187 bits (475), Expect = 3e-47
Identities = 115/298 (38%), Positives = 167/298 (56%), Gaps = 14/298 (4%)
Frame = +3
Query: 3 KNTDNMKRAELMLGNASLIDARVFIEPEDVALVTQRGQNREKLNLAFVANLFNTYPALIV 182
+ D+++RAE ML A + R F+ DV + KLNLAF+ANLFN YPAL
Sbjct: 326 REKDDIQRAECMLQQAERLGCRQFVTATDVV------RGNPKLNLAFIANLFNKYPALHK 379
Query: 183 DSXXXXXXXXXXX-----KTYRNWINSMGVTPYVKDLYSDXXXXXXXXXXXXXXQPGIVE 347
+T+RNW+NS+GV P V LYSD + V+
Sbjct: 380 PENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIKVP-VD 438
Query: 348 WKKIVRVFDPKKK-IFQVLGNCAHVIECAK-KLQLSIVNLSADNIKDATPNLTLGLCFQM 521
W ++ + PK + L NC + ++ K + + S+V ++ ++ + LTL L +Q+
Sbjct: 439 WNRVNKPPYPKLGGNMKKLENCNYAVDLGKNQAKFSLVGIAGQDLNEGNRTLTLALVWQL 498
Query: 522 LRCYTMKLLSKVLPGKKDDKDIVA-WANGKLEAANKTSKITGFRDQSIATSKPVLDLIDS 698
+R YT+ +L + G+K + DI+ W N L+ A K+S I F+D I+TS PVLDLID+
Sbjct: 499 MRRYTLNILEDIGGGQKVNDDIIVNWVNTTLKEAQKSSSIASFKDPKISTSLPVLDLIDA 558
Query: 699 IVPNSVDYKLLTGEPLQD------AKFAISQARRIGARIYALPQHLVDVNQKMVMTIY 854
I P S++Y LL E L D AK+AIS AR+IGAR+YALP+ LV+VN KMVMT++
Sbjct: 559 IQPGSINYDLLKTENLDDEEKLNNAKYAISMARKIGARVYALPEDLVEVNPKMVMTVF 616
Score = 46.2 bits (108), Expect = 1e-04
Identities = 46/183 (25%), Positives = 80/183 (43%), Gaps = 29/183 (15%)
Frame = +3
Query: 378 KKKI--FQVLGNCAHVIECAKKLQLSIVNLSADNIKDATPNLTLGLCFQMLR-------- 527
KKK+ F + N + A + +VN+ A+++K+ P L LGL +Q+++
Sbjct: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIE 241
Query: 528 -CYTMKLLSKVLPGK--------KDDKDIVAWANGKLEAANKTSKITGFRDQSIATSKPV 680
L++ + G+ ++ ++ WAN LE A T KIT F I SK
Sbjct: 242 LSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCT-KITNF-STDIKDSKAY 299
Query: 681 LDLIDSIVPNS---------VDYK-LLTGEPLQDAKFAISQARRIGARIYALPQHLVDVN 830
L++ + P +D L + +Q A+ + QA R+G R + +V N
Sbjct: 300 YHLLEQVAPKGDEEGIPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGN 359
Query: 831 QKM 839
K+
Sbjct: 360 PKL 362
>sp|Q63598|PLST_RAT T-plastin (Plastin-3)
Length = 627
Score = 186 bits (472), Expect = 7e-47
Identities = 113/296 (38%), Positives = 166/296 (56%), Gaps = 14/296 (4%)
Frame = +3
Query: 9 TDNMKRAELMLGNASLIDARVFIEPEDVALVTQRGQNREKLNLAFVANLFNTYPALIVDS 188
TD++KRAE ML A + R F+ P DV KLNLAFVANLFN YPAL
Sbjct: 328 TDDLKRAESMLQQADKLGCRQFVTPADVV------SGNPKLNLAFVANLFNKYPALTKPE 381
Query: 189 XXXXXXXXXXX-----KTYRNWINSMGVTPYVKDLYSDXXXXXXXXXXXXXXQPGIVEWK 353
+T+RNW+NS+GV P+V LY D + V+W
Sbjct: 382 NQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYVDLQDALVILQLYERIKVP-VDWS 440
Query: 354 KIVRVFDPKKKI-FQVLGNCAHVIECAK-KLQLSIVNLSADNIKDATPNLTLGLCFQMLR 527
K+ + PK + L NC + +E K + + S+V + ++ D P LTL + +Q++R
Sbjct: 441 KVNKPPYPKLGANMKKLENCNYAVELGKNQAKFSLVGIGGQDLNDGNPTLTLAVVWQLMR 500
Query: 528 CYTMKLLSKVLPGKKDDKDIVA-WANGKLEAANKTSKITGFRDQSIATSKPVLDLIDSIV 704
YT+ ++ + G+K DI+ W NG L A K++ I F+D++I++S V+DLID+I
Sbjct: 501 RYTLNVMEDLGEGQKATDDIIVNWVNGTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQ 560
Query: 705 PNSVDYKLL-TGEPLQD-----AKFAISQARRIGARIYALPQHLVDVNQKMVMTIY 854
P ++Y L+ TG ++ AK+A+S ARRIGAR+YALP+ LV+V KMVMT++
Sbjct: 561 PGCINYDLVKTGNLTEEDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVF 616
Score = 42.4 bits (98), Expect = 0.002
Identities = 45/187 (24%), Positives = 78/187 (41%), Gaps = 33/187 (17%)
Frame = +3
Query: 378 KKKI--FQVLGNCAHVIECAKKLQLSIVNLSADNIKDATPNLTLGLCFQMLRC------- 530
KKK+ F + N + A + +VN+ A++++ P+L LGL +Q+++
Sbjct: 182 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIE 241
Query: 531 --------------YTMKLLSKVLPGKKDDKDIVAWANGKLEAANKTSKITGFRDQSIAT 668
T++ L K+ P ++ ++ WAN LE + KI F I
Sbjct: 242 LSRNEALAALLRDGETLEELMKLSP----EELLLRWANFHLENSG-WQKINNF-SADIKD 295
Query: 669 SKPVLDLIDSIVPNS-------VDYKLLTGEPLQDAKFA---ISQARRIGARIYALPQHL 818
SK L++ I P +D + D K A + QA ++G R + P +
Sbjct: 296 SKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADV 355
Query: 819 VDVNQKM 839
V N K+
Sbjct: 356 VSGNPKL 362
>sp|Q99K51|PLST_MOUSE T-plastin (Plastin-3)
Length = 627
Score = 185 bits (470), Expect = 1e-46
Identities = 112/296 (37%), Positives = 164/296 (55%), Gaps = 14/296 (4%)
Frame = +3
Query: 9 TDNMKRAELMLGNASLIDARVFIEPEDVALVTQRGQNREKLNLAFVANLFNTYPALIVDS 188
TD++KRAE ML A + R F+ P DV KLNLAFVANLFN YPAL
Sbjct: 328 TDDLKRAESMLQQADKLGCRQFVTPADVV------SGNPKLNLAFVANLFNKYPALTKPE 381
Query: 189 XXXXXXXXXXX-----KTYRNWINSMGVTPYVKDLYSDXXXXXXXXXXXXXXQPGIVEWK 353
+T+RNW+NS+GV P+V LY+D + V+W
Sbjct: 382 NQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIKVP-VDWS 440
Query: 354 KIVRVFDPKKKI-FQVLGNCAHVIECAKK-LQLSIVNLSADNIKDATPNLTLGLCFQMLR 527
K+ + PK + L NC + +E K + S+V + ++ D P LTL + +Q++R
Sbjct: 441 KVNKPPYPKLGANMKKLENCNYAVELGKNPAKFSLVGIGGQDLNDGNPTLTLAVVWQLMR 500
Query: 528 CYTMKLLSKVLPGKKDDKDIVA-WANGKLEAANKTSKITGFRDQSIATSKPVLDLIDSIV 704
YT+ +L + G+K + DI+ W N L A K++ I F+D++I++S V+DLID+I
Sbjct: 501 RYTLNVLEDLGEGQKANDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQ 560
Query: 705 PNSVDYKLLTGEPLQD------AKFAISQARRIGARIYALPQHLVDVNQKMVMTIY 854
P ++Y L+ L + AK+A+S ARRIGAR+YALP+ LV+V KMVMT++
Sbjct: 561 PGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVF 616
Score = 42.4 bits (98), Expect = 0.002
Identities = 45/187 (24%), Positives = 78/187 (41%), Gaps = 33/187 (17%)
Frame = +3
Query: 378 KKKI--FQVLGNCAHVIECAKKLQLSIVNLSADNIKDATPNLTLGLCFQMLRC------- 530
KKK+ F + N + A + +VN+ A++++ P+L LGL +Q+++
Sbjct: 182 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIE 241
Query: 531 --------------YTMKLLSKVLPGKKDDKDIVAWANGKLEAANKTSKITGFRDQSIAT 668
T++ L K+ P ++ ++ WAN LE + KI F I
Sbjct: 242 LSRNEALAALLRDGETLEELMKLSP----EELLLRWANFHLENSG-WQKINNF-SADIKD 295
Query: 669 SKPVLDLIDSIVPNS-------VDYKLLTGEPLQDAKFA---ISQARRIGARIYALPQHL 818
SK L++ I P +D + D K A + QA ++G R + P +
Sbjct: 296 SKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADV 355
Query: 819 VDVNQKM 839
V N K+
Sbjct: 356 VSGNPKL 362
>sp|O88818|PLST_CRIGR T-plastin (Plastin-3)
Length = 627
Score = 185 bits (469), Expect = 2e-46
Identities = 112/296 (37%), Positives = 164/296 (55%), Gaps = 14/296 (4%)
Frame = +3
Query: 9 TDNMKRAELMLGNASLIDARVFIEPEDVALVTQRGQNREKLNLAFVANLFNTYPALIVDS 188
TD++KRAE ML A + R F+ P DV KLNLAFVANLFN YPAL
Sbjct: 328 TDDLKRAESMLQQADKLGCRQFVTPADVV------SGNPKLNLAFVANLFNKYPALTKPE 381
Query: 189 XXXXXXXXXXX-----KTYRNWINSMGVTPYVKDLYSDXXXXXXXXXXXXXXQPGIVEWK 353
+T+RNW+NS+GV P+V LY+D + V+W
Sbjct: 382 NQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIKVP-VDWS 440
Query: 354 KIVRVFDPKKKI-FQVLGNCAHVIECAKK-LQLSIVNLSADNIKDATPNLTLGLCFQMLR 527
K+ + PK + L NC + +E K + S+V + ++ D P LTL + +Q++R
Sbjct: 441 KVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNPTLTLAVVWQLMR 500
Query: 528 CYTMKLLSKVLPGKKDDKDIVA-WANGKLEAANKTSKITGFRDQSIATSKPVLDLIDSIV 704
YT+ +L + G+K + DI+ W N L A K++ I F+D++I++S V+DLID+I
Sbjct: 501 RYTLNVLEDLGEGQKANDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQ 560
Query: 705 PNSVDYKLLTGEPLQD------AKFAISQARRIGARIYALPQHLVDVNQKMVMTIY 854
P ++Y L+ L + AK+A+S ARRIGAR+YALP+ LV+V KMVMT++
Sbjct: 561 PGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVF 616
Score = 42.4 bits (98), Expect = 0.002
Identities = 45/187 (24%), Positives = 78/187 (41%), Gaps = 33/187 (17%)
Frame = +3
Query: 378 KKKI--FQVLGNCAHVIECAKKLQLSIVNLSADNIKDATPNLTLGLCFQMLRC------- 530
KKK+ F + N + A + +VN+ A++++ P+L LGL +Q+++
Sbjct: 182 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIE 241
Query: 531 --------------YTMKLLSKVLPGKKDDKDIVAWANGKLEAANKTSKITGFRDQSIAT 668
T++ L K+ P ++ ++ WAN LE + KI F I
Sbjct: 242 LSRNEALAALLRDGETLEELMKLSP----EELLLRWANFHLENSG-WQKINNF-SADIKD 295
Query: 669 SKPVLDLIDSIVPNS-------VDYKLLTGEPLQDAKFA---ISQARRIGARIYALPQHL 818
SK L++ I P +D + D K A + QA ++G R + P +
Sbjct: 296 SKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADV 355
Query: 819 VDVNQKM 839
V N K+
Sbjct: 356 VSGNPKL 362
>sp|P13797|PLST_HUMAN T-plastin (Plastin-3)
Length = 627
Score = 183 bits (464), Expect = 6e-46
Identities = 112/296 (37%), Positives = 163/296 (55%), Gaps = 14/296 (4%)
Frame = +3
Query: 9 TDNMKRAELMLGNASLIDARVFIEPEDVALVTQRGQNREKLNLAFVANLFNTYPALIVDS 188
TD++KRAE ML A + R F+ P DV KLNLAFVANLFN YPAL
Sbjct: 328 TDDLKRAESMLQQADKLGCRQFVTPADVV------SGNPKLNLAFVANLFNKYPALTKPE 381
Query: 189 XXXXXXXXXXX-----KTYRNWINSMGVTPYVKDLYSDXXXXXXXXXXXXXXQPGIVEWK 353
+T+RNW+NS+GV P+V LY+D + V+W
Sbjct: 382 NQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIKVP-VDWS 440
Query: 354 KIVRVFDPKKKI-FQVLGNCAHVIECAKK-LQLSIVNLSADNIKDATPNLTLGLCFQMLR 527
K+ + PK + L NC + +E K + S+V + ++ D LTL L +Q++R
Sbjct: 441 KVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMR 500
Query: 528 CYTMKLLSKVLPGKKDDKDIVA-WANGKLEAANKTSKITGFRDQSIATSKPVLDLIDSIV 704
YT+ +L + G+K + DI+ W N L A K++ I F+D++I++S V+DLID+I
Sbjct: 501 RYTLNVLEDLGDGQKANDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQ 560
Query: 705 PNSVDYKLLTGEPLQD------AKFAISQARRIGARIYALPQHLVDVNQKMVMTIY 854
P ++Y L+ L + AK+A+S ARRIGAR+YALP+ LV+V KMVMT++
Sbjct: 561 PGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVF 616
Score = 42.4 bits (98), Expect = 0.002
Identities = 45/187 (24%), Positives = 78/187 (41%), Gaps = 33/187 (17%)
Frame = +3
Query: 378 KKKI--FQVLGNCAHVIECAKKLQLSIVNLSADNIKDATPNLTLGLCFQMLRC------- 530
KKK+ F + N + A + +VN+ A++++ P+L LGL +Q+++
Sbjct: 182 KKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIE 241
Query: 531 --------------YTMKLLSKVLPGKKDDKDIVAWANGKLEAANKTSKITGFRDQSIAT 668
T++ L K+ P ++ ++ WAN LE + KI F I
Sbjct: 242 LSRNEALAALLRDGETLEELMKLSP----EELLLRWANFHLENSG-WQKINNF-SADIKD 295
Query: 669 SKPVLDLIDSIVPNS-------VDYKLLTGEPLQDAKFA---ISQARRIGARIYALPQHL 818
SK L++ I P +D + D K A + QA ++G R + P +
Sbjct: 296 SKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADV 355
Query: 819 VDVNQKM 839
V N K+
Sbjct: 356 VSGNPKL 362
>sp|Q6P698|PLSL_BRARE L-plastin (Lymphocyte cytosolic plastin 1)
Length = 624
Score = 182 bits (462), Expect = 1e-45
Identities = 118/298 (39%), Positives = 165/298 (55%), Gaps = 14/298 (4%)
Frame = +3
Query: 3 KNTDNMKRAELMLGNASLIDARVFIEPEDVALVTQRGQNREKLNLAFVANLFNTYPALIV 182
+ D++KRAE ML A + R F+ DV + KLNLA+VANLFN YPAL
Sbjct: 324 REKDDLKRAECMLEQADRLGCRQFVTATDVV------RGNPKLNLAYVANLFNKYPALKK 377
Query: 183 DSXXXXXXXXXXX-----KTYRNWINSMGVTPYVKDLYSDXXXXXXXXXXXXXXQPGIVE 347
+T+RNW+NS+GV P V LY D + V+
Sbjct: 378 PENQDIDWSSIEGETREERTFRNWMNSLGVNPRVNHLYVDLADALVIFQLYEKIKVP-VD 436
Query: 348 WKKIVRVFDPKK-KIFQVLGNCAHVIECAKK-LQLSIVNLSADNIKDATPNLTLGLCFQM 521
W K+ + PK + L NC + +E KK + S+V ++ ++ + LTL L +Q+
Sbjct: 437 WDKVNKPPYPKLGSNMKKLENCNYAVELGKKEAKFSLVGIAGQDLNEGNRTLTLALLWQL 496
Query: 522 LRCYTMKLLSKVLPGKKD-DKDIVAWANGKLEAANKTSKITGFRDQSIATSKPVLDLIDS 698
+R YT+ +L + G+K D+ IV W N L A K + I+GF+D SI++S PVLDLID+
Sbjct: 497 MRRYTLNILEDLGDGQKIIDETIVQWVNETLTQAGKGT-ISGFKDGSISSSMPVLDLIDA 555
Query: 699 IVPNSVDYKLLTGEPLQD------AKFAISQARRIGARIYALPQHLVDVNQKMVMTIY 854
I P S+ Y LL E L D AK+AIS AR+IGAR+YALP+ LV+V KMVMT++
Sbjct: 556 IQPGSIRYDLLKAEDLTDEKKLNNAKYAISMARKIGARVYALPEDLVEVKPKMVMTVF 613
Score = 39.3 bits (90), Expect = 0.014
Identities = 43/183 (23%), Positives = 80/183 (43%), Gaps = 29/183 (15%)
Frame = +3
Query: 378 KKKI--FQVLGNCAHVIECAKKLQLSIVNLSADNIKDATPNLTLGLCFQMLRCYTM---- 539
KKK+ F + N + A + +VN+ A+++K+ +L LGL +Q+++
Sbjct: 180 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGRQHLVLGLLWQVIKIGLFADIE 239
Query: 540 ----KLLSKVLPGKKDDKDIV---------AWANGKLEAANKTSKITGFRDQSIATSKPV 680
+ L +L + +D+V WAN LE A KI F I SK
Sbjct: 240 ISRNEALIALLRDGESLEDLVKLSPEELLLRWANYHLEEAG-CPKINNF-SSDIKDSKAY 297
Query: 681 LDLIDSIVPNSVDYKL------LTG----EPLQDAKFAISQARRIGARIYALPQHLVDVN 830
++++ + P + + ++G + L+ A+ + QA R+G R + +V N
Sbjct: 298 YNILNQVAPKRDEEGIPAIPIDISGIREKDDLKRAECMLEQADRLGCRQFVTATDVVRGN 357
Query: 831 QKM 839
K+
Sbjct: 358 PKL 360
>sp|P54680|FIMB_DICDI Fimbrin
Length = 610
Score = 172 bits (437), Expect = 8e-43
Identities = 106/294 (36%), Positives = 167/294 (56%), Gaps = 11/294 (3%)
Frame = +3
Query: 6 NTDNM-KRAELMLGNASLIDARVFIEPEDVALVTQRGQNREKLNLAFVANLFNTYPALIV 182
N N+ +RA +L NA + + F++P+D+ Q KLNLAFVANLFNT+PAL
Sbjct: 316 NISNLDQRAVKVLENADKLGCKKFLKPKDIVTGFQ------KLNLAFVANLFNTHPALEP 369
Query: 183 DSXXXXXXXXXXXKTYRNWINSMGVTPYVKDLYSDXXXXXXXXXXXXXXQPGIVEWKKIV 362
KT+RNW+NS+GV P+V +LY PG+V+ KK+
Sbjct: 370 VEDVVIIEETREEKTFRNWMNSLGVDPFVNNLYEGTYDGLILIQLFDKIYPGLVDHKKVN 429
Query: 363 RVFDPKKKI---FQVLGNCAHVIECAKKLQLSIVNLSADNIKDATPNLTLGLCFQMLRCY 533
+ P K + + + NC + I+ K + S+V + N+ D LTL + +Q++R +
Sbjct: 430 --YPPYKAMGAEMKKIENCNYAIQLGKDCKYSLVGIDGKNVYDKNKTLTLSILWQLMRGH 487
Query: 534 TMKLLSKVLPGKKD--DKDIVAWANGKLEAANKTSKITGFRDQSIATSKPVLDLIDSIVP 707
+ +L+ + K D DIV AN KL AA K +I+GF+D +I+T P+LD+I+++ P
Sbjct: 488 VISILTALSGSGKPIADADIVNVANSKLSAAGK-KQISGFKDSTISTGIPILDVIEAVRP 546
Query: 708 NSVDYKLLTG-----EPLQDAKFAISQARRIGARIYALPQHLVDVNQKMVMTIY 854
SVD L+ + L +AK A+S AR++GA ++ALP+ +V+V KMV+T++
Sbjct: 547 GSVDPALVATSGSAEDNLLNAKLAVSTARKVGAVVFALPEDIVEVKPKMVLTLF 600
Score = 31.2 bits (69), Expect = 3.8
Identities = 39/180 (21%), Positives = 76/180 (42%), Gaps = 21/180 (11%)
Frame = +3
Query: 363 RVFDPKK-KIFQVLGNCAHVIECAKKLQLSIVNLSADNIKDATPNLTLGLCFQMLRCYTM 539
RV + K F++ N I AK + ++VN+ A ++ + +L +GL +Q+++
Sbjct: 174 RVLNKKNLNAFRINENQVLCINSAKAIGCNVVNIGAGDLVEGRAHLIMGLTWQIIKIGLF 233
Query: 540 KLLS--------KVLPGKKDDKD---------IVAWANGKLEAANKTSKITGFRDQSIAT 668
++ ++L + +D ++ W N L AA ++ F I
Sbjct: 234 ARINLTNHPELYRLLHDGETIEDLLKLPVEEILLRWFNYHLAAAGSQRRVKNF-SGDIKD 292
Query: 669 SKPVLDLIDSIVPN--SVDYKLLTGEPL-QDAKFAISQARRIGARIYALPQHLVDVNQKM 839
S+ L+ I P V+ L L Q A + A ++G + + P+ +V QK+
Sbjct: 293 SECYTILLKQIAPKDAGVETSALNISNLDQRAVKVLENADKLGCKKFLKPKDIVTGFQKL 352
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,000,035
Number of Sequences: 369166
Number of extensions: 1514702
Number of successful extensions: 3617
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3441
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3541
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8438301375
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)