Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_D04
(961 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8IZF2|GP116_HUMAN Probable G-protein coupled receptor 1... 63 1e-09
sp|Q9WVT0|GP116_RAT Probable G-protein coupled receptor 116... 60 9e-09
sp|P29534|VCAM1_RAT Vascular cell adhesion protein 1 precur... 50 1e-05
sp|P14781|CNTN1_CHICK Contactin 1 precursor (Neural cell re... 49 2e-05
sp|P20241|NRG_DROME Neuroglian precursor 49 2e-05
sp|Q90688|MYPC3_CHICK Myosin-binding protein C, cardiac-typ... 48 4e-05
sp|P98159|NUDEL_DROME Serine protease nudel precursor 48 5e-05
sp|Q06561|UNC52_CAEEL Basement membrane proteoglycan precur... 47 6e-05
sp|O94856|NFASC_HUMAN Neurofascin precursor 47 6e-05
sp|Q63191|AEGP_RAT Apical endosomal glycoprotein precursor 47 8e-05
>sp|Q8IZF2|GP116_HUMAN Probable G-protein coupled receptor 116 precursor
Length = 1346
Score = 62.8 bits (151), Expect = 1e-09
Identities = 63/233 (27%), Positives = 97/233 (41%), Gaps = 23/233 (9%)
Frame = +1
Query: 16 EAESRGTNVEWFFNNEKLNSFNSETYNIYR---NDRTYVSIITLVNITPKNEGLYSCKVD 186
E E +NV W + ++L NS ++IY N+ T VS +T+ NITP + G Y CK+
Sbjct: 294 EKEVLSSNVSWRYEEQQLEIQNSSRFSIYTALFNNMTSVSKLTIHNITPGDAGEYVCKLI 353
Query: 187 NII------KKANLIVVKEDPTLTINPERIIRNEGEPVEFHCRGNNIPQFSNTKIKWSFR 348
I KK +++ ++ + N E + + PV +C +S K++W
Sbjct: 354 LDIFEYECKKKIDVMPIQ----ILANEEMKVMCDNNPVSLNCCSQGNVNWS--KVEW--- 404
Query: 349 SRDGRIFLPNVVSENRWELVNSNDTPETSF-ISIQGSLYKDDG------------FYTCT 489
++G+I +P TPET S K DG YTC
Sbjct: 405 KQEGKINIPG--------------TPETDIDSSCSRYTLKADGTQCPSGSSGTTVIYTCE 450
Query: 490 APDGSQKTAELIIKRREDSL-RLTITPETVKVRDGQPIIVECFSESEKTGEPY 645
IK S+ LTITP+ + V +GQ ++C S+ E Y
Sbjct: 451 FISAYGARGSANIKVTFISVANLTITPDPISVSEGQNFSIKCISDVSNYDEVY 503
>sp|Q9WVT0|GP116_RAT Probable G-protein coupled receptor 116 precursor (G-protein
coupled hepta-helical receptor Ig-hepta)
Length = 1349
Score = 60.1 bits (144), Expect = 9e-09
Identities = 56/233 (24%), Positives = 97/233 (41%), Gaps = 23/233 (9%)
Frame = +1
Query: 16 EAESRGTNVEWFFNNEKLNSFNSETYNIYR---NDRTYVSIITLVNITPKNEGLYSCKVD 186
E+E +N WF+ ++ + NS+ ++I+ N+ + V+ +T+ N T + GLY C V
Sbjct: 292 ESEFVSSNTSWFYGEKRSDIQNSDKFSIHTSIINNISLVTRLTIFNFTQHDAGLYGCNVT 351
Query: 187 ------NIIKKANLIVVKEDPTLTINPERIIRNEGEPVEFHCRGNNIPQFSNTKIKWSFR 348
++K ++ ++ + ER + + P+ +C NI +S +I+W
Sbjct: 352 LDIFEYGTVRKLDVTPIR----ILAKEERKVVCDNNPISLNCCSENIANWS--RIEWK-- 403
Query: 349 SRDGRIFLPNVVSENRWELVNSNDTPETSFISIQGSL-YKDDG------------FYTCT 489
++G+I N TPET S + K DG YTC
Sbjct: 404 -QEGKI--------------NIEGTPETDLESSCSTYTLKADGTQCPSGSSGTTVIYTCE 448
Query: 490 APDG-SQKTAELIIKRREDSLRLTITPETVKVRDGQPIIVECFSESEKTGEPY 645
K ++ I LTITP+ + V +GQ + C S+ E Y
Sbjct: 449 FVSVYGAKGSKNIAVTFTSVANLTITPDPISVSEGQSFSITCLSDVSSFDEVY 501
>sp|P29534|VCAM1_RAT Vascular cell adhesion protein 1 precursor (V-CAM 1)
Length = 739
Score = 49.7 bits (117), Expect = 1e-05
Identities = 35/136 (25%), Positives = 64/136 (47%), Gaps = 3/136 (2%)
Frame = +1
Query: 214 VVKEDPTLTINPERIIRNEGEPVEFHCRGNNIPQFSNTKIKWSFRSRDGRIFLPNVVSEN 393
V ++PT+ ++P + EG PV C + P KI WS + ++G +
Sbjct: 509 VAPKEPTIWVSPSPV-PEEGSPVNLTCSSDGFP---TPKILWSRQLKNGEL--------- 555
Query: 394 RWELVNSNDTPETSFISIQGSLYKDDGFYTCTAPDG---SQKTAELIIKRREDSLRLTIT 564
+ ++ N T +S + +D G Y C + S+K+ ELII+ ++LT+
Sbjct: 556 --QPLSQNTT-----LSFMATKMEDSGIYVCEGINEAGISKKSVELIIQGSSKDIQLTVF 608
Query: 565 PETVKVRDGQPIIVEC 612
P + V++G +I+ C
Sbjct: 609 P-SKSVKEGDTVIISC 623
>sp|P14781|CNTN1_CHICK Contactin 1 precursor (Neural cell recognition molecule F11)
Length = 1010
Score = 48.9 bits (115), Expect = 2e-05
Identities = 41/174 (23%), Positives = 71/174 (40%), Gaps = 6/174 (3%)
Frame = +1
Query: 130 ITLVNITPKNEGLYSCKVDN----IIKKANLIVVKEDPTLTINP--ERIIRNEGEPVEFH 291
+ + +T ++ G+Y C +N I A L +V PT +NP ++I+ +G V
Sbjct: 367 LRIQGLTFEDAGMYQCIAENAHGIIYANAELKIVASPPTFELNPMKKKILAAKGGRVIIE 426
Query: 292 CRGNNIPQFSNTKIKWSFRSRDGRIFLPNVVSENRWELVNSNDTPETSFISIQGSLYKDD 471
C+ P+ K WS G L N + W+ + I D+
Sbjct: 427 CKPKAAPK---PKFSWS----KGTELLVNGSRIHIWD---------DGSLEIINVTKLDE 470
Query: 472 GFYTCTAPDGSQKTAELIIKRREDSLRLTITPETVKVRDGQPIIVECFSESEKT 633
G YTC A + K + ++ R+T+ P V V G+ ++C + + T
Sbjct: 471 GRYTCFAENNRGKANSTGVLEMTEATRITLAPLNVDVTVGENATMQCIASHDPT 524
Score = 38.9 bits (89), Expect = 0.022
Identities = 46/195 (23%), Positives = 75/195 (38%), Gaps = 8/195 (4%)
Frame = +1
Query: 124 SIITLVNITPKNEGLYSCKVDNI---IKKANLIVVKEDPTLTINPERIIRNEGEPVEFHC 294
+++ + NI ++EGLY C+ +N K + V+ P + ++ G + + C
Sbjct: 284 AVLKIFNIQYEDEGLYECEAENYKGKDKHQARVYVQASPEWVEHINDTEKDIGSDLYWPC 343
Query: 295 --RGNNIPQFSNTKIKWSFRSRDGRIFLPNVVSENRWELVNSNDTPETSFISIQGSLYKD 468
G IP I+W L N VS + EL IQG ++D
Sbjct: 344 VATGKPIP-----TIRW----------LKNGVSFRKGEL------------RIQGLTFED 376
Query: 469 DGFYTCTAPDGS---QKTAELIIKRREDSLRLTITPETVKVRDGQPIIVECFSESEKTGE 639
G Y C A + AEL I + L + + G +I+EC ++
Sbjct: 377 AGMYQCIAENAHGIIYANAELKIVASPPTFELNPMKKKILAAKGGRVIIECKPKAAP--- 433
Query: 640 PYGEPKFTMESGRSL 684
+PKF+ G L
Sbjct: 434 ---KPKFSWSKGTEL 445
>sp|P20241|NRG_DROME Neuroglian precursor
Length = 1302
Score = 48.9 bits (115), Expect = 2e-05
Identities = 45/177 (25%), Positives = 71/177 (40%), Gaps = 7/177 (3%)
Frame = +1
Query: 130 ITLVNITPKNEGLYSCKVDN----IIKKANLIVVKEDPTLTINPERIIRNEGEPVEFHCR 297
I ++N+ + G Y C N + K L V E PT++ P + +G V CR
Sbjct: 395 IRIINLVKGDTGNYGCNATNSLGYVYKDVYLNVQAEPPTISEAPAAVSTVDGRNVTIKCR 454
Query: 298 GNNIPQFSNTKIKWSFRSRDGRIFLPNVVSENRWELVNSNDTPETSFISIQGSLYKDDGF 477
N P+ +KW S N ++ R+ + + D + IQ + D G
Sbjct: 455 VNGSPK---PLVKWLRAS--------NWLTGGRYNVQANGD------LEIQDVTFSDAGK 497
Query: 478 YTCTAPD---GSQKTAELIIKRREDSLRLTITPETVKVRDGQPIIVECFSESEKTGE 639
YTC A + Q L++K + R+T P+ +V GQ C + T E
Sbjct: 498 YTCYAQNKFGEIQADGSLVVK---EHTRITQEPQNYEVAAGQSATFRCNEAHDDTLE 551
Score = 40.4 bits (93), Expect = 0.007
Identities = 37/158 (23%), Positives = 62/158 (39%), Gaps = 8/158 (5%)
Frame = +1
Query: 163 GLYSCKVDNIIKKAN----LIVVKEDPTLTINPERIIRNEGEPVEFHCRGNNIPQFSNTK 330
G Y+C V N + A ++ V P T PE E E V F CR +P+ K
Sbjct: 313 GTYTCDVSNGVGNAQSFSIILNVNSVPYFTKEPEIATAAEDEEVVFECRAAGVPE---PK 369
Query: 331 IKWSFRSRDGRIFLPN---VVSENRWELVNSNDTPETSFISIQGSLYKDDGFYTCTAPDG 501
I W + PN V++N ++N ++G D G Y C A +
Sbjct: 370 ISWIHNGKPIEQSTPNPRRTVTDNTIRIIN----------LVKG----DTGNYGCNATNS 415
Query: 502 -SQKTAELIIKRREDSLRLTITPETVKVRDGQPIIVEC 612
++ + + + ++ P V DG+ + ++C
Sbjct: 416 LGYVYKDVYLNVQAEPPTISEAPAAVSTVDGRNVTIKC 453
>sp|Q90688|MYPC3_CHICK Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein,
cardiac muscle isoform)
Length = 1272
Score = 48.1 bits (113), Expect = 4e-05
Identities = 59/247 (23%), Positives = 106/247 (42%), Gaps = 2/247 (0%)
Frame = +1
Query: 16 EAESRGTNVEWFFNNEKLNSFNSE-TYNIYRNDRTYVSIITLVNITPKNEGLYSCKVDNI 192
E + +V+W N +++ S+ + N R I+T+ + + ++ Y C V
Sbjct: 385 EVANPDADVKWLKNGQEIQVSGSKYIFEAIGNKR----ILTINHCSLADDAAYECVVAEE 440
Query: 193 IKKANLIVVKEDPTLTINP-ERIIRNEGEPVEFHCRGNNIPQFSNTKIKWSFRSRDGRIF 369
K + VKE P L +P E + GE VEF C + +KW +DG
Sbjct: 441 -KSFTELFVKEPPILITHPLEDQMVMVGERVEFECEVSE----EGATVKWE---KDG--- 489
Query: 370 LPNVVSENRWELVNSNDTPETSFISIQGSLYKDDGFYTCTAPDGSQKTAELIIKRREDSL 549
+ E ++ D + ++ I S +D G YT +G AELI++ ++ +
Sbjct: 490 -VELTREETFKYRFKKDGKK-QYLIINESTKEDSGHYTVKT-NGGVSVAELIVQEKKLEV 546
Query: 550 RLTITPETVKVRDGQPIIVECFSESEKTGEPYGEPKFTMESGRSLSLDPRLDQQNVGQSR 729
+I TVK RD E E+ K +++G+ + D R+ ++G+
Sbjct: 547 YQSIADLTVKARDQAVFKCEVSDENVK--------GIWLKNGKEVVPDERIKISHIGRIH 598
Query: 730 IRLSIKD 750
+L+I+D
Sbjct: 599 -KLTIED 604
>sp|P98159|NUDEL_DROME Serine protease nudel precursor
Length = 2616
Score = 47.8 bits (112), Expect = 5e-05
Identities = 23/62 (37%), Positives = 35/62 (56%), Gaps = 2/62 (3%)
Frame = +1
Query: 772 NFKVECHAGI-QVKTATIFLENQCPPNYRRCNNG-ECQPSGKFCDGIPNCADASDEDPTL 945
N + +CH G + +T + QC P +C +C P KFCD +P+C D +DE PT+
Sbjct: 2328 NGRSDCHDGSDEEETKCRQQKQQCAPGEMKCRTSFKCVPKSKFCDHVPDCEDMTDE-PTI 2386
Query: 946 CN 951
C+
Sbjct: 2387 CS 2388
Score = 36.2 bits (82), Expect = 0.14
Identities = 26/99 (26%), Positives = 40/99 (40%), Gaps = 19/99 (19%)
Frame = +1
Query: 709 QNVGQSRIRLSIKDGLQTIDNNFKVECHAGIQVKTAT-----------------IFLENQ 837
Q GQS+ + G Q+ +N + Q TA I ++
Sbjct: 831 QGAGQSQTSSQQQQGGQSAFSNANFKMRHANQTNTANQQGQIIYASYAGLPQQPIQERSR 890
Query: 838 CP-PNYRRC-NNGECQPSGKFCDGIPNCADASDEDPTLC 948
CP P+ C EC P+ ++CD + +C+D SDE C
Sbjct: 891 CPEPDQFSCFGQQECIPAARWCDNVVDCSDGSDESACTC 929
Score = 36.2 bits (82), Expect = 0.14
Identities = 14/33 (42%), Positives = 18/33 (54%)
Frame = +1
Query: 856 RCNNGECQPSGKFCDGIPNCADASDEDPTLCNK 954
RC G C P C+G +C D SDE+ T C +
Sbjct: 2314 RCPLGTCLPQAAMCNGRSDCHDGSDEEETKCRQ 2346
>sp|Q06561|UNC52_CAEEL Basement membrane proteoglycan precursor (Perlecan homolog)
(Uncoordinated protein 52)
Length = 3375
Score = 47.4 bits (111), Expect = 6e-05
Identities = 42/164 (25%), Positives = 68/164 (41%), Gaps = 26/164 (15%)
Frame = +1
Query: 547 LRLTITPETVKVRDGQPIIVECFSESE-----------KTGEPYGEPKFTMESGRSLSLD 693
+++T+ P +VRDG+ + EC + + + G P P +SG L+++
Sbjct: 45 VQITVFPSEKEVRDGRDVSFECRARTSDNSVYPTVRWARVGGPL--PSSAHDSGGRLTIN 102
Query: 694 P-RLDQQ-----------NVGQSRIRLSIKD-GLQTIDNNFKVECHAGIQVKTATIFLEN 834
P +L N ++R LS+ G Q + N + AG
Sbjct: 103 PVQLSDAGTYICVSDYNGNTVEARATLSVVSYGPQEVSNGLR---QAG------------ 147
Query: 835 QCPPNYRRCNNGECQPSGKFCDGIPNCADASDED--PTLCNKCD 960
QC + + C N EC + CDG P+C D SDE P + C+
Sbjct: 148 QCMADEKACGNNECVKNDYVCDGEPDCRDRSDEANCPAISRTCE 191
Score = 41.6 bits (96), Expect = 0.003
Identities = 48/222 (21%), Positives = 85/222 (38%), Gaps = 16/222 (7%)
Frame = +1
Query: 106 NDRTYVSIITLVNITPKNEGLYSCKVDNIIKKAN---LIVVKE-----DPTLTINPERII 261
N + Y + L + +N G Y C I + A L+ + + P I+P ++
Sbjct: 1177 NAKAYDGYLVLKGVEAENAGQYRCTATTITQYATDDALLTISKRISGRPPQPVIDPPHLV 1236
Query: 262 RNEGEPVEFHCRGNNIPQFSNTKIKWSFRSRDGRIFLPNVVSENRWELVNSNDTPETSFI 441
NEGEP F C +P + +I W G LP+ V + + +
Sbjct: 1237 VNEGEPAAFRCW---VPGIPDCQITWHREQLGGP--LPHGVYQT------------GNAL 1279
Query: 442 SIQGSLYKDDGFYTCTAPD--GSQKTAELIIKRREDSLRLTITPETVKVRDGQPIIVECF 615
I S G Y C+A + G+ ++ +++ ++ + + P V QP +C+
Sbjct: 1280 KIPQSQLHHAGRYICSAANQYGTGQSPPAVLEVKKPVIPPKVDPIRQTVDRDQPARFKCW 1339
Query: 616 SESE-----KTGEPYGEP-KFTMESGRSLSLDPRLDQQNVGQ 723
+ P G P ++ + + PR Q VGQ
Sbjct: 1340 VPGNSNVQLRWSRPGGAPLPSGVQEQQGILHIPRASDQEVGQ 1381
Score = 33.1 bits (74), Expect = 1.2
Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 1/57 (1%)
Frame = +1
Query: 766 DNNFKVECHAGIQVKTATIFLENQCPPNYRRCNNG-ECQPSGKFCDGIPNCADASDE 933
DN+ ++ C+A + C P +C++ +C PS CDG +C D SDE
Sbjct: 217 DNSDELNCNAKPS--------SSDCKPTEFQCHDRRQCVPSSFHCDGTNDCHDGSDE 265
>sp|O94856|NFASC_HUMAN Neurofascin precursor
Length = 1240
Score = 47.4 bits (111), Expect = 6e-05
Identities = 37/154 (24%), Positives = 67/154 (43%), Gaps = 3/154 (1%)
Frame = +1
Query: 40 VEWFFNNEKLNSFNSETYNIYRNDRTYVSIITLVNITPKNEGLYSCKVDNIIKKAN---L 210
+ WF N + N + Y++Y N + +I +++G+Y+C NI+ KA
Sbjct: 462 LRWFKNGQGSN-LDGGNYHVYENGSLEIKMIR-----KEDQGIYTCVATNILGKAENQVR 515
Query: 211 IVVKEDPTLTINPERIIRNEGEPVEFHCRGNNIPQFSNTKIKWSFRSRDGRIFLPNVVSE 390
+ VK+ + PE + G V+ CR + P + K+ S+ D +++ N + +
Sbjct: 516 LEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDP---SLKLTVSWLKDDEPLYIGNRMKK 572
Query: 391 NRWELVNSNDTPETSFISIQGSLYKDDGFYTCTA 492
E ++I G +D G YTC A
Sbjct: 573 ------------EDDSLTIFGVAERDQGSYTCVA 594
>sp|Q63191|AEGP_RAT Apical endosomal glycoprotein precursor
Length = 1216
Score = 47.0 bits (110), Expect = 8e-05
Identities = 17/39 (43%), Positives = 23/39 (58%)
Frame = +1
Query: 835 QCPPNYRRCNNGECQPSGKFCDGIPNCADASDEDPTLCN 951
+CP + C N C + CDG NC D+SDEDP +C+
Sbjct: 230 RCPLGHHHCQNKACVEPHQLCDGEDNCGDSSDEDPLICS 268
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.316 0.135 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 112,986,460
Number of Sequences: 369166
Number of extensions: 2421491
Number of successful extensions: 7767
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6650
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7690
length of database: 68,354,980
effective HSP length: 111
effective length of database: 47,849,395
effective search space used: 9952674160
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)