Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_C24
(893 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P67962|KC1A_CHICK Casein kinase I, alpha isoform (CKI-al... 375 e-103
sp|P48729|KC1A_HUMAN Casein kinase I, alpha isoform (CKI-al... 375 e-103
sp|P67829|KC1A_SHEEP Casein kinase I, alpha isoform (CKI-al... 375 e-103
sp|P97633|KC1A_RAT Casein kinase I, alpha isoform (CKI-alph... 375 e-103
sp|Q8N752|KC1AL_HUMAN Casein kinase I, alpha-like isoform (... 367 e-101
sp|P42168|YKL1_CAEEL Putative casein kinase I C03C10.1 in c... 362 e-100
sp|P54367|KC1A_DROME Casein kinase I, alpha isoform (CKI-al... 347 3e-95
sp|Q06486|KC1D_RAT Casein kinase I, delta isoform (CKI-delt... 332 9e-91
sp|P48730|KC1D_HUMAN Casein kinase I, delta isoform (CKI-de... 332 9e-91
sp|P49674|KC1E_HUMAN Casein kinase I, epsilon isoform (CKI-... 331 2e-90
>sp|P67962|KC1A_CHICK Casein kinase I, alpha isoform (CKI-alpha) (CK1)
sp|P67963|KC1A_XENLA Casein kinase I, alpha isoform (CKI-alpha) (CK1)
Length = 337
Score = 375 bits (962), Expect = e-103
Identities = 176/231 (76%), Positives = 200/231 (86%)
Frame = +3
Query: 3 LVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEFIHSKNFIHRDIKPDNFLMGIG 182
LVMDLLGPSLEDLFNFC RRFTMKTVLMLA+QM++R+E++H+KNFIHRDIKPDNFLMGIG
Sbjct: 88 LVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIG 147
Query: 183 RHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYASINAHAGIEQSRRDDMESM 362
RHCNKLF++DFGL+KKY+D +T+ HIPYREDKNLTGTARYASINAH GIEQSRRDDMES+
Sbjct: 148 RHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESL 207
Query: 363 GYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIEVLCKSFPPEFAFYLEYCRNLK 542
GYV MYF R++LPWQGLKA KKQKYE+I EKK STP+EVLCK FP EFA YL YCR L+
Sbjct: 208 GYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLR 267
Query: 543 FDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLKQKAVGMQQQSHQCGGG 695
F+EAP+Y LR+ F LFRTLN YDY FDWT+LKQKA QQ + G G
Sbjct: 268 FEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAA--QQAASSSGQG 316
>sp|P48729|KC1A_HUMAN Casein kinase I, alpha isoform (CKI-alpha) (CK1)
sp|Q8BK63|KC1A_MOUSE Casein kinase I, alpha isoform (CKI-alpha) (CK1)
Length = 337
Score = 375 bits (962), Expect = e-103
Identities = 176/231 (76%), Positives = 200/231 (86%)
Frame = +3
Query: 3 LVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEFIHSKNFIHRDIKPDNFLMGIG 182
LVMDLLGPSLEDLFNFC RRFTMKTVLMLA+QM++R+E++H+KNFIHRDIKPDNFLMGIG
Sbjct: 88 LVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIG 147
Query: 183 RHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYASINAHAGIEQSRRDDMESM 362
RHCNKLF++DFGL+KKY+D +T+ HIPYREDKNLTGTARYASINAH GIEQSRRDDMES+
Sbjct: 148 RHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESL 207
Query: 363 GYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIEVLCKSFPPEFAFYLEYCRNLK 542
GYV MYF R++LPWQGLKA KKQKYE+I EKK STP+EVLCK FP EFA YL YCR L+
Sbjct: 208 GYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLR 267
Query: 543 FDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLKQKAVGMQQQSHQCGGG 695
F+EAP+Y LR+ F LFRTLN YDY FDWT+LKQKA QQ + G G
Sbjct: 268 FEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAA--QQAASSSGQG 316
>sp|P67829|KC1A_SHEEP Casein kinase I, alpha isoform (CKI-alpha) (CK1)
sp|P67828|KC1A_RABIT Casein kinase I, alpha isoform (CKI-alpha) (CK1)
sp|P67827|KC1A_BOVIN Casein kinase I, alpha isoform (CKI-alpha) (CK1)
Length = 325
Score = 375 bits (962), Expect = e-103
Identities = 176/231 (76%), Positives = 200/231 (86%)
Frame = +3
Query: 3 LVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEFIHSKNFIHRDIKPDNFLMGIG 182
LVMDLLGPSLEDLFNFC RRFTMKTVLMLA+QM++R+E++H+KNFIHRDIKPDNFLMGIG
Sbjct: 88 LVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIG 147
Query: 183 RHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYASINAHAGIEQSRRDDMESM 362
RHCNKLF++DFGL+KKY+D +T+ HIPYREDKNLTGTARYASINAH GIEQSRRDDMES+
Sbjct: 148 RHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESL 207
Query: 363 GYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIEVLCKSFPPEFAFYLEYCRNLK 542
GYV MYF R++LPWQGLKA KKQKYE+I EKK STP+EVLCK FP EFA YL YCR L+
Sbjct: 208 GYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLR 267
Query: 543 FDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLKQKAVGMQQQSHQCGGG 695
F+EAP+Y LR+ F LFRTLN YDY FDWT+LKQKA QQ + G G
Sbjct: 268 FEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAA--QQAASSSGQG 316
>sp|P97633|KC1A_RAT Casein kinase I, alpha isoform (CKI-alpha) (CK1)
Length = 325
Score = 375 bits (962), Expect = e-103
Identities = 176/231 (76%), Positives = 200/231 (86%)
Frame = +3
Query: 3 LVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEFIHSKNFIHRDIKPDNFLMGIG 182
LVMDLLGPSLEDLFNFC RRFTMKTVLMLA+QM++R+E++H+KNFIHRDIKPDNFLMGIG
Sbjct: 88 LVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIG 147
Query: 183 RHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYASINAHAGIEQSRRDDMESM 362
RHCNKLF++DFGL+KKY+D +T+ HIPYREDKNLTGTARYASINAH GIEQSRRDDMES+
Sbjct: 148 RHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESL 207
Query: 363 GYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIEVLCKSFPPEFAFYLEYCRNLK 542
GYV MYF R++LPWQGLKA KKQKYE+I EKK STP+EVLCK FP EFA YL YCR L+
Sbjct: 208 GYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLR 267
Query: 543 FDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLKQKAVGMQQQSHQCGGG 695
F+EAP+Y LR+ F LFRTLN YDY FDWT+LKQKA QQ + G G
Sbjct: 268 FEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAA--QQAASSSGQG 316
>sp|Q8N752|KC1AL_HUMAN Casein kinase I, alpha-like isoform (CKI-alpha-like) (CK1)
Length = 337
Score = 367 bits (942), Expect = e-101
Identities = 171/231 (74%), Positives = 197/231 (85%)
Frame = +3
Query: 3 LVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEFIHSKNFIHRDIKPDNFLMGIG 182
LVMDLLGPSLEDLFNFC RRFTMKTVLMLA+QM++R+E++H+KNF+HRDIKPDNFLMG G
Sbjct: 88 LVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFLHRDIKPDNFLMGTG 147
Query: 183 RHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYASINAHAGIEQSRRDDMESM 362
RHCNKLF++DFGL+KKY+D +T+ HIPYREDK+L GT RYASINAH GIEQSRRDDMES+
Sbjct: 148 RHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYASINAHLGIEQSRRDDMESL 207
Query: 363 GYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIEVLCKSFPPEFAFYLEYCRNLK 542
GYVFMYF R++LPWQGLKA KKQKYE+I EKK STP+EVLCK FP EFA YL YCR L+
Sbjct: 208 GYVFMYFNRTSLPWQGLKAMTKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLR 267
Query: 543 FDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLKQKAVGMQQQSHQCGGG 695
F+E P+Y LR+ F LFRTLN YDY FDWT+LKQKA QQ + G G
Sbjct: 268 FEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAA--QQAASSSGQG 316
>sp|P42168|YKL1_CAEEL Putative casein kinase I C03C10.1 in chromosome III
Length = 341
Score = 362 bits (929), Expect = e-100
Identities = 173/232 (74%), Positives = 194/232 (83%)
Frame = +3
Query: 3 LVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEFIHSKNFIHRDIKPDNFLMGIG 182
LVMDLLGPSLEDLFNFC RRFTMKTVLMLA+QM+ R+E++H KNFIHRDIKPDNFLMGIG
Sbjct: 87 LVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMIGRIEYVHVKNFIHRDIKPDNFLMGIG 146
Query: 183 RHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYASINAHAGIEQSRRDDMESM 362
RHCNKLF++DFGL+KKY+D++T+ HIPYREDKNLTGTARYASINAH GIEQSRRDDMES+
Sbjct: 147 RHCNKLFLIDFGLAKKYRDSRTRTHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESL 206
Query: 363 GYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIEVLCKSFPPEFAFYLEYCRNLK 542
GYV MYF R TLPWQGLKA KKQKYE+I EKK +T +E LCK FP EF YL Y R L+
Sbjct: 207 GYVLMYFNRGTLPWQGLKAATKKQKYEKISEKKMTTSVEHLCKGFPAEFPMYLSYTRGLR 266
Query: 543 FDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLKQKAVGMQQQSHQCGGGG 698
FDE+P+Y LR+ F LFRTLN YDY FDWT+LKQKA QQS G G
Sbjct: 267 FDESPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKA----QQSQSSGVPG 314
>sp|P54367|KC1A_DROME Casein kinase I, alpha isoform (CKI-alpha) (DmCK1)
Length = 337
Score = 347 bits (890), Expect = 3e-95
Identities = 162/217 (74%), Positives = 186/217 (85%)
Frame = +3
Query: 3 LVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEFIHSKNFIHRDIKPDNFLMGIG 182
LVMDLLGPSLEDLFNFC R FT+KTVLML +QM+ R+E+IH K FIHRDIKPDNFLMGIG
Sbjct: 91 LVMDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIGRLEYIHLKCFIHRDIKPDNFLMGIG 150
Query: 183 RHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYASINAHAGIEQSRRDDMESM 362
RHCNKLF++DFGL+KK++D T+ HI YREDKNLTGTARYASINAH GIEQSRRDDMES+
Sbjct: 151 RHCNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYASINAHLGIEQSRRDDMESL 210
Query: 363 GYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIEVLCKSFPPEFAFYLEYCRNLK 542
GYV MYF R LPWQG+KAN K+QKYE+I EKK STPIEVLCK P EF+ YL YCR+L+
Sbjct: 211 GYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKGSPAEFSMYLNYCRSLR 270
Query: 543 FDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLKQK 653
F+E P+Y LR+ F LFRTLN YDY++DWT+LKQK
Sbjct: 271 FEEQPDYMYLRQLFRILFRTLNHQYDYIYDWTMLKQK 307
>sp|Q06486|KC1D_RAT Casein kinase I, delta isoform (CKI-delta)
sp|Q9DC28|KC1D_MOUSE Casein kinase I, delta isoform (CKI-delta) (CKId)
Length = 415
Score = 332 bits (851), Expect = 9e-91
Identities = 149/215 (69%), Positives = 184/215 (85%)
Frame = +3
Query: 3 LVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEFIHSKNFIHRDIKPDNFLMGIG 182
+VM+LLGPSLEDLFNFC R+F++KTVL+LA+QM++R+E+IHSKNFIHRD+KPDNFLMG+G
Sbjct: 80 MVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLG 139
Query: 183 RHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYASINAHAGIEQSRRDDMESM 362
+ N ++++DFGL+KKY+D +T HIPYRE+KNLTGTARYASIN H GIEQSRRDD+ES+
Sbjct: 140 KKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESL 199
Query: 363 GYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIEVLCKSFPPEFAFYLEYCRNLK 542
GYV MYF +LPWQGLKA K+QKYERI EKK STPIEVLCK +P EFA YL +CR+L+
Sbjct: 200 GYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLR 259
Query: 543 FDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLK 647
FD+ P+Y LR+ F NLF F+YDYVFDW +LK
Sbjct: 260 FDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLK 294
>sp|P48730|KC1D_HUMAN Casein kinase I, delta isoform (CKI-delta) (CKId)
Length = 415
Score = 332 bits (851), Expect = 9e-91
Identities = 149/215 (69%), Positives = 184/215 (85%)
Frame = +3
Query: 3 LVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEFIHSKNFIHRDIKPDNFLMGIG 182
+VM+LLGPSLEDLFNFC R+F++KTVL+LA+QM++R+E+IHSKNFIHRD+KPDNFLMG+G
Sbjct: 80 MVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLG 139
Query: 183 RHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYASINAHAGIEQSRRDDMESM 362
+ N ++++DFGL+KKY+D +T HIPYRE+KNLTGTARYASIN H GIEQSRRDD+ES+
Sbjct: 140 KKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESL 199
Query: 363 GYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIEVLCKSFPPEFAFYLEYCRNLK 542
GYV MYF +LPWQGLKA K+QKYERI EKK STPIEVLCK +P EFA YL +CR+L+
Sbjct: 200 GYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLR 259
Query: 543 FDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLK 647
FD+ P+Y LR+ F NLF F+YDYVFDW +LK
Sbjct: 260 FDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLK 294
>sp|P49674|KC1E_HUMAN Casein kinase I, epsilon isoform (CKI-epsilon) (CKIe)
Length = 416
Score = 331 bits (848), Expect = 2e-90
Identities = 148/215 (68%), Positives = 184/215 (85%)
Frame = +3
Query: 3 LVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEFIHSKNFIHRDIKPDNFLMGIG 182
+VM+LLGPSLEDLFNFC R+F++KTVL+LA+QM++R+E+IHSKNFIHRD+KPDNFLMG+G
Sbjct: 80 MVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLG 139
Query: 183 RHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYASINAHAGIEQSRRDDMESM 362
+ N ++++DFGL+KKY+D +T HIPYRE+KNLTGTARYASIN H GIEQSRRDD+ES+
Sbjct: 140 KKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESL 199
Query: 363 GYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIEVLCKSFPPEFAFYLEYCRNLK 542
GYV MYF +LPWQGLKA K+QKYERI EKK STPIEVLCK +P EF+ YL +CR+L+
Sbjct: 200 GYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLR 259
Query: 543 FDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLK 647
FD+ P+Y LR+ F NLF F+YDYVFDW +LK
Sbjct: 260 FDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLK 294
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 101,113,140
Number of Sequences: 369166
Number of extensions: 2030771
Number of successful extensions: 7439
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 7010
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7322
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8982382310
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)