Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_C17
(645 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8K3J1|NUIM_MOUSE NADH-ubiquinone oxidoreductase 23 kDa ... 300 2e-81
sp|Q60HE3|NUIM_MACFA NADH-ubiquinone oxidoreductase 23 kDa ... 299 4e-81
sp|O00217|NUIM_HUMAN NADH-ubiquinone oxidoreductase 23 kDa ... 297 1e-80
sp|P42028|NUIM_BOVIN NADH-ubiquinone oxidoreductase 23 kDa ... 295 7e-80
sp|Q22619|NUIM_CAEEL NADH-ubiquinone oxidoreductase 23 kDa ... 288 6e-78
sp|Q12644|NUIM_NEUCR NADH-ubiquinone oxidoreductase 23 kDa ... 263 2e-70
sp|Q42599|NUIM_ARATH NADH-ubiquinone oxidoreductase 23 kDa ... 263 3e-70
sp|O21233|NUIM_RECAM NADH-ubiquinone oxidoreductase subunit 8 261 1e-69
sp|P80269|NUIM_SOLTU NADH-ubiquinone oxidoreductase 23 kDa ... 261 1e-69
sp|O24143|NUIM_TOBAC NADH-ubiquinone oxidoreductase 23 kDa ... 258 7e-69
>sp|Q8K3J1|NUIM_MOUSE NADH-ubiquinone oxidoreductase 23 kDa subunit, mitochondrial
precursor (Complex I-23KD) (CI-23KD) (TYKY subunit)
Length = 212
Score = 300 bits (769), Expect = 2e-81
Identities = 141/177 (79%), Positives = 157/177 (88%), Gaps = 2/177 (1%)
Frame = +3
Query: 57 YKTISKKGEATT--LKEAVDNGMNLYALTELFKGLGVTVGMIFREPATINYPFEKGPLSP 230
YK ++KK + + +K A DN + TEL +GLG+T+ +FREPATINYPFEKGPLSP
Sbjct: 36 YKYVNKKEQESEVDMKSATDNAARILMWTELIRGLGMTLSYLFREPATINYPFEKGPLSP 95
Query: 231 RFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAETRADGSRRTTRYDIDMTKCIFC 410
RFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAE RADGSRRTTRYDIDMTKCI+C
Sbjct: 96 RFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEPRADGSRRTTRYDIDMTKCIYC 155
Query: 411 GFCQEACPVDAIVEGPNFEYSTETHEELLYNKEKLLDNGDRWEPEIQANIEADYVYR 581
GFCQEACPVDAIVEGPNFE+STETHEELLYNKEKLL+NGD+WE EI ANI+ADY+YR
Sbjct: 156 GFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKLLNNGDKWEAEIAANIQADYLYR 212
>sp|Q60HE3|NUIM_MACFA NADH-ubiquinone oxidoreductase 23 kDa subunit, mitochondrial
precursor (Complex I-23KD) (CI-23KD) (TYKY subunit)
Length = 210
Score = 299 bits (766), Expect = 4e-81
Identities = 138/175 (78%), Positives = 153/175 (87%)
Frame = +3
Query: 57 YKTISKKGEATTLKEAVDNGMNLYALTELFKGLGVTVGMIFREPATINYPFEKGPLSPRF 236
YK ++ + T +K D TELF+GLG+T+ +FREPATINYPFEKGPLSPRF
Sbjct: 36 YKYVNMQESKTDMKSVTDRAARTLLWTELFRGLGMTLSYLFREPATINYPFEKGPLSPRF 95
Query: 237 RGEHALRRYPSGEERCIACKLCEAICPAQAITIEAETRADGSRRTTRYDIDMTKCIFCGF 416
RGEHALRRYPSGEERCIACKLCEA+CPAQAITIEAE RADGSRRTTRYDIDMTKCI+CGF
Sbjct: 96 RGEHALRRYPSGEERCIACKLCEAVCPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGF 155
Query: 417 CQEACPVDAIVEGPNFEYSTETHEELLYNKEKLLDNGDRWEPEIQANIEADYVYR 581
CQEACPVDAIVEGPNFE+STETHEELLYNKEKLL+NGD+WE EI ANI+ADY+YR
Sbjct: 156 CQEACPVDAIVEGPNFEFSTETHEELLYNKEKLLNNGDKWEAEIAANIQADYLYR 210
>sp|O00217|NUIM_HUMAN NADH-ubiquinone oxidoreductase 23 kDa subunit, mitochondrial
precursor (Complex I-23KD) (CI-23KD) (TYKY subunit)
Length = 210
Score = 297 bits (761), Expect = 1e-80
Identities = 138/175 (78%), Positives = 152/175 (86%)
Frame = +3
Query: 57 YKTISKKGEATTLKEAVDNGMNLYALTELFKGLGVTVGMIFREPATINYPFEKGPLSPRF 236
YK ++ + +K D TELF+GLG+T+ +FREPATINYPFEKGPLSPRF
Sbjct: 36 YKYVNMQDPEMDMKSVTDRAARTLLWTELFRGLGMTLSYLFREPATINYPFEKGPLSPRF 95
Query: 237 RGEHALRRYPSGEERCIACKLCEAICPAQAITIEAETRADGSRRTTRYDIDMTKCIFCGF 416
RGEHALRRYPSGEERCIACKLCEAICPAQAITIEAE RADGSRRTTRYDIDMTKCI+CGF
Sbjct: 96 RGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGF 155
Query: 417 CQEACPVDAIVEGPNFEYSTETHEELLYNKEKLLDNGDRWEPEIQANIEADYVYR 581
CQEACPVDAIVEGPNFE+STETHEELLYNKEKLL+NGD+WE EI ANI+ADY+YR
Sbjct: 156 CQEACPVDAIVEGPNFEFSTETHEELLYNKEKLLNNGDKWEAEIAANIQADYLYR 210
>sp|P42028|NUIM_BOVIN NADH-ubiquinone oxidoreductase 23 kDa subunit, mitochondrial
precursor (Complex I-23KD) (CI-23KD) (TYKY subunit)
Length = 212
Score = 295 bits (755), Expect = 7e-80
Identities = 136/175 (77%), Positives = 152/175 (86%)
Frame = +3
Query: 57 YKTISKKGEATTLKEAVDNGMNLYALTELFKGLGVTVGMIFREPATINYPFEKGPLSPRF 236
YK ++ + + +K D TEL +GLG+T+ +FREPATINYPFEKGPLSPRF
Sbjct: 38 YKYVNLREPSMDMKSVTDRAAQTLLWTELIRGLGMTLSYLFREPATINYPFEKGPLSPRF 97
Query: 237 RGEHALRRYPSGEERCIACKLCEAICPAQAITIEAETRADGSRRTTRYDIDMTKCIFCGF 416
RGEHALRRYPSGEERCIACKLCEA+CPAQAITIEAE RADGSRRTTRYDIDMTKCI+CGF
Sbjct: 98 RGEHALRRYPSGEERCIACKLCEAVCPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGF 157
Query: 417 CQEACPVDAIVEGPNFEYSTETHEELLYNKEKLLDNGDRWEPEIQANIEADYVYR 581
CQEACPVDAIVEGPNFE+STETHEELLYNKEKLL+NGD+WE EI ANI+ADY+YR
Sbjct: 158 CQEACPVDAIVEGPNFEFSTETHEELLYNKEKLLNNGDKWEAEIAANIQADYLYR 212
>sp|Q22619|NUIM_CAEEL NADH-ubiquinone oxidoreductase 23 kDa subunit, mitochondrial
precursor (Complex I-23KD) (CI-23KD)
Length = 212
Score = 288 bits (738), Expect = 6e-78
Identities = 138/184 (75%), Positives = 155/184 (84%), Gaps = 1/184 (0%)
Frame = +3
Query: 33 STQSKLNCYKTISKKGEAT-TLKEAVDNGMNLYALTELFKGLGVTVGMIFREPATINYPF 209
+T K + YK + E TL ++ G++ TELF+G GV +G +F EPATINYPF
Sbjct: 29 NTIQKRSNYKFVGMPNETDGTLAGDLNYGLHNVFFTELFRGFGVMLGHVFMEPATINYPF 88
Query: 210 EKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAETRADGSRRTTRYDID 389
EKGPLS RFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAETR DGSRRTTRYDID
Sbjct: 89 EKGPLSSRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAETRPDGSRRTTRYDID 148
Query: 390 MTKCIFCGFCQEACPVDAIVEGPNFEYSTETHEELLYNKEKLLDNGDRWEPEIQANIEAD 569
MTKCI+CG CQEACPVDAIVEGPNFEYSTETHEELLYNKEKLL NGDRWEPE+ +N++A+
Sbjct: 149 MTKCIYCGLCQEACPVDAIVEGPNFEYSTETHEELLYNKEKLLLNGDRWEPELASNLQAE 208
Query: 570 YVYR 581
Y+YR
Sbjct: 209 YLYR 212
>sp|Q12644|NUIM_NEUCR NADH-ubiquinone oxidoreductase 23 kDa subunit, mitochondrial
precursor (Complex I-23KD) (CI-23KD)
Length = 219
Score = 263 bits (673), Expect = 2e-70
Identities = 122/162 (75%), Positives = 136/162 (83%)
Frame = +3
Query: 96 KEAVDNGMNLYALTELFKGLGVTVGMIFREPATINYPFEKGPLSPRFRGEHALRRYPSGE 275
+ +D + LTE+F+G+ V + FR P TI YPFEKGP+SPRFRGEHALRRYPSGE
Sbjct: 58 EHVLDKNGRYFLLTEMFRGMYVAMEQFFRPPYTIYYPFEKGPISPRFRGEHALRRYPSGE 117
Query: 276 ERCIACKLCEAICPAQAITIEAETRADGSRRTTRYDIDMTKCIFCGFCQEACPVDAIVEG 455
ERCIACKLCEA+CPAQAITIEAE RADGSRRTTRYDIDMTKCI+CGFCQE+CPVDAIVE
Sbjct: 118 ERCIACKLCEAVCPAQAITIEAEERADGSRRTTRYDIDMTKCIYCGFCQESCPVDAIVES 177
Query: 456 PNFEYSTETHEELLYNKEKLLDNGDRWEPEIQANIEADYVYR 581
PN EY+TET EELLYNKEKLL NGD+WEPE+ A I AD YR
Sbjct: 178 PNAEYATETREELLYNKEKLLSNGDKWEPELAAAIRADSPYR 219
>sp|Q42599|NUIM_ARATH NADH-ubiquinone oxidoreductase 23 kDa subunit, mitochondrial
precursor (Complex I-23KD) (CI-23KD) (Complex I-28.5KD)
(CI-28.5KD)
Length = 222
Score = 263 bits (672), Expect = 3e-70
Identities = 120/158 (75%), Positives = 137/158 (86%)
Frame = +3
Query: 108 DNGMNLYALTELFKGLGVTVGMIFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCI 287
+ +N LTE+ +GL +T+ F TINYPFEKGPLSPRFRGEHALRRYP+GEERCI
Sbjct: 65 ERSINTLFLTEMVRGLSLTLKYFFDPKVTINYPFEKGPLSPRFRGEHALRRYPTGEERCI 124
Query: 288 ACKLCEAICPAQAITIEAETRADGSRRTTRYDIDMTKCIFCGFCQEACPVDAIVEGPNFE 467
ACKLCEA+CPAQAITIEAE R DGSRRTTRYDIDMTKCI+CGFCQEACPVDAIVEGPNFE
Sbjct: 125 ACKLCEAVCPAQAITIEAEEREDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFE 184
Query: 468 YSTETHEELLYNKEKLLDNGDRWEPEIQANIEADYVYR 581
++TETHEELLY+KEKLL+NGDRWE EI N+ ++ +YR
Sbjct: 185 FATETHEELLYDKEKLLENGDRWETEIAENLRSESLYR 222
>sp|O21233|NUIM_RECAM NADH-ubiquinone oxidoreductase subunit 8
Length = 162
Score = 261 bits (667), Expect = 1e-69
Identities = 120/150 (80%), Positives = 134/150 (89%)
Frame = +3
Query: 132 LTELFKGLGVTVGMIFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAI 311
LTEL KG+ +T+ FR+ T+NYPFEKGPLSPRFRGEHALRRY +GEERCIACKLCEAI
Sbjct: 13 LTELVKGMSLTLDYFFRKKVTLNYPFEKGPLSPRFRGEHALRRYQTGEERCIACKLCEAI 72
Query: 312 CPAQAITIEAETRADGSRRTTRYDIDMTKCIFCGFCQEACPVDAIVEGPNFEYSTETHEE 491
CPAQAITIE+E R DGSRRTTRYDIDMTKCI+CGFCQEACPVDAIVEGPNFE++TETHEE
Sbjct: 73 CPAQAITIESEPRIDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFATETHEE 132
Query: 492 LLYNKEKLLDNGDRWEPEIQANIEADYVYR 581
LLY+KEKLL NGDRWE EI AN+ + +YR
Sbjct: 133 LLYDKEKLLQNGDRWETEIAANLANEALYR 162
>sp|P80269|NUIM_SOLTU NADH-ubiquinone oxidoreductase 23 kDa subunit, mitochondrial
precursor (Complex I-23KD) (CI-23KD) (Complex I-28.5KD)
(CI-28.5KD)
Length = 229
Score = 261 bits (666), Expect = 1e-69
Identities = 120/158 (75%), Positives = 137/158 (86%)
Frame = +3
Query: 108 DNGMNLYALTELFKGLGVTVGMIFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCI 287
+ +N LTE+ +GL +T+ F + TINYPFEKGPLSPRFRGEHALRRY +GEERCI
Sbjct: 72 ERSINTLFLTEMVRGLMLTLKYFFEKKVTINYPFEKGPLSPRFRGEHALRRYATGEERCI 131
Query: 288 ACKLCEAICPAQAITIEAETRADGSRRTTRYDIDMTKCIFCGFCQEACPVDAIVEGPNFE 467
ACKLCEAICPAQAITIEAE R DGSRRTTRYDIDMTKCI+CGFCQEACPVDAIVEGPNFE
Sbjct: 132 ACKLCEAICPAQAITIEAEEREDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFE 191
Query: 468 YSTETHEELLYNKEKLLDNGDRWEPEIQANIEADYVYR 581
++TETHEELLY+KEKLL+NGDRWE EI N+ ++ +YR
Sbjct: 192 FATETHEELLYDKEKLLENGDRWETEIAENLRSESLYR 229
>sp|O24143|NUIM_TOBAC NADH-ubiquinone oxidoreductase 23 kDa subunit, mitochondrial
precursor (Complex I-23KD) (CI-23KD) (Complex I-28.5KD)
(CI-28.5KD)
Length = 230
Score = 258 bits (660), Expect = 7e-69
Identities = 119/155 (76%), Positives = 135/155 (87%)
Frame = +3
Query: 117 MNLYALTELFKGLGVTVGMIFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACK 296
+N LTE+ +GL +T+ F + TINYPFEKGPLSPRFRGE LRRYP+GEERCIACK
Sbjct: 76 INTLFLTEMVRGLMLTLKYFFEKKVTINYPFEKGPLSPRFRGEQPLRRYPTGEERCIACK 135
Query: 297 LCEAICPAQAITIEAETRADGSRRTTRYDIDMTKCIFCGFCQEACPVDAIVEGPNFEYST 476
LCEAICPAQAITIEAE R DGSRRTTRYDIDMTKCI+CGFCQEACPVDAIVEGPNFE++T
Sbjct: 136 LCEAICPAQAITIEAEAREDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFAT 195
Query: 477 ETHEELLYNKEKLLDNGDRWEPEIQANIEADYVYR 581
ETHEELLY+KEKLL+NGDRWE EI N+ ++ +YR
Sbjct: 196 ETHEELLYDKEKLLENGDRWETEIAENLRSESLYR 230
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,214,828
Number of Sequences: 369166
Number of extensions: 1427663
Number of successful extensions: 4536
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3627
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4205
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5267491560
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)