Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_C13
(621 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P30101|PDIA3_HUMAN Protein disulfide-isomerase A3 precur... 200 2e-51
sp|P38657|PDIA3_BOVIN Protein disulfide-isomerase A3 precur... 199 4e-51
sp|P27773|PDIA3_MOUSE Protein disulfide-isomerase A3 precur... 197 2e-50
sp|P11598|PDIA3_RAT Protein disulfide-isomerase A3 precurso... 193 3e-49
sp|P38658|ERP60_SCHMA Probable protein disulfide-isomerase ... 189 5e-48
sp|P13667|PDIA4_HUMAN Protein disulfide-isomerase A4 precur... 161 1e-39
sp|P38659|PDIA4_RAT Protein disulfide-isomerase A4 precurso... 158 9e-39
sp|P55059|PDI_HUMIN Protein disulfide-isomerase precursor (... 158 1e-38
sp|P08003|PDIA4_MOUSE Protein disulfide-isomerase A4 precur... 157 2e-38
sp|P34329|PDIA4_CAEEL Probable protein disulfide-isomerase ... 148 1e-35
>sp|P30101|PDIA3_HUMAN Protein disulfide-isomerase A3 precursor (Disulfide isomerase
ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57)
(58 kDa glucose regulated protein)
Length = 505
Score = 200 bits (509), Expect = 2e-51
Identities = 94/149 (63%), Positives = 117/149 (78%), Gaps = 2/149 (1%)
Frame = +3
Query: 6 MAEDFTME--AFEKFINDFLNEQVPVYLKSETIPEKNDEPVKVVVAKNFDALVNDPTKDV 179
M E+F+ + A E+F+ D+ + + YLKSE IPE ND PVKVVVA+NFD +VN+ KDV
Sbjct: 338 MQEEFSRDGKALERFLQDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDV 397
Query: 180 LIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDATANDVPSPYEVTGFPTIYFAP 359
LIEFYAPWCGHCK+L PKY+EL +KLS + +IVIAKMDATANDVPSPYEV GFPTIYF+P
Sbjct: 398 LIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSP 457
Query: 360 KNSKNSPKSYNGGREVDDMLKYIASESTS 446
N K +PK Y GGRE+ D + Y+ E+T+
Sbjct: 458 ANKKLNPKKYEGGRELSDFISYLQREATN 486
Score = 70.9 bits (172), Expect = 3e-12
Identities = 37/103 (35%), Positives = 63/103 (61%), Gaps = 3/103 (2%)
Frame = +3
Query: 141 NFDALVNDPTKD--VLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDATAN-DV 311
NF++ ++D +L+EF+APWCGHCK LAP+YE A +L G + +AK+D TAN +
Sbjct: 34 NFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKG--IVPLAKVDCTANTNT 91
Query: 312 PSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 440
+ Y V+G+PT+ + +Y+G R D ++ ++ ++
Sbjct: 92 CNKYGVSGYPTLKIFRDGEEAG--AYDGPRTADGIVSHLKKQA 132
>sp|P38657|PDIA3_BOVIN Protein disulfide-isomerase A3 precursor (Disulfide isomerase
ER-60) (ERP60) (58 kDa microsomal protein) (P58) (ERp57)
Length = 505
Score = 199 bits (507), Expect = 4e-51
Identities = 93/149 (62%), Positives = 116/149 (77%), Gaps = 2/149 (1%)
Frame = +3
Query: 6 MAEDFTME--AFEKFINDFLNEQVPVYLKSETIPEKNDEPVKVVVAKNFDALVNDPTKDV 179
M E+F+ + A E+F+ D+ + + YLKSE IPE ND PVKVVVA+NFD +VN+ KDV
Sbjct: 338 MQEEFSRDGKALERFLEDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDV 397
Query: 180 LIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDATANDVPSPYEVTGFPTIYFAP 359
LIEFYAPWCGHCK+L PKY+EL +KL + +IVIAKMDATANDVPSPYEV GFPTIYF+P
Sbjct: 398 LIEFYAPWCGHCKNLEPKYKELGEKLRKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSP 457
Query: 360 KNSKNSPKSYNGGREVDDMLKYIASESTS 446
N K +PK Y GGRE+ D + Y+ E+T+
Sbjct: 458 ANKKQNPKKYEGGRELSDFISYLKREATN 486
Score = 72.8 bits (177), Expect = 7e-13
Identities = 37/103 (35%), Positives = 63/103 (61%), Gaps = 3/103 (2%)
Frame = +3
Query: 141 NFDALVNDPTKD--VLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDATAN-DV 311
NF++ + D +L+EF+APWCGHCK LAP+YE A +L G + +AK+D TAN +
Sbjct: 34 NFESRITDTGSSGLMLVEFFAPWCGHCKKLAPEYEAAATRLKG--IVPLAKVDCTANTNT 91
Query: 312 PSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 440
+ Y V+G+PT+ ++ +Y+G R D ++ ++ ++
Sbjct: 92 CNKYGVSGYPTLKIFRDGEESG--AYDGPRTADGIVSHLKKQA 132
>sp|P27773|PDIA3_MOUSE Protein disulfide-isomerase A3 precursor (Disulfide isomerase
ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57)
Length = 504
Score = 197 bits (500), Expect = 2e-50
Identities = 92/149 (61%), Positives = 118/149 (79%), Gaps = 2/149 (1%)
Frame = +3
Query: 6 MAEDFTME--AFEKFINDFLNEQVPVYLKSETIPEKNDEPVKVVVAKNFDALVNDPTKDV 179
M E+F+ + A E+F+ ++ + + YLKSE IPE N+ PVKVVVA+NFD +VN+ KDV
Sbjct: 337 MQEEFSRDGKALEQFLQEYFDGNLKRYLKSEPIPESNEGPVKVVVAENFDDIVNEEDKDV 396
Query: 180 LIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDATANDVPSPYEVTGFPTIYFAP 359
LIEFYAPWCGHCK+L PKY+EL +KLS + +IVIAKMDATANDVPSPYEV GFPTIYF+P
Sbjct: 397 LIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVKGFPTIYFSP 456
Query: 360 KNSKNSPKSYNGGREVDDMLKYIASESTS 446
N K +PK Y GGRE++D + Y+ E+T+
Sbjct: 457 ANKKLTPKKYEGGRELNDFISYLQREATN 485
Score = 68.9 bits (167), Expect = 1e-11
Identities = 37/104 (35%), Positives = 63/104 (60%), Gaps = 3/104 (2%)
Frame = +3
Query: 138 KNFDALVNDPTKD--VLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDATAN-D 308
+NF++ V+D +L+EF+APWCGHCK LAP+YE A +L + +AK+D TAN +
Sbjct: 33 ENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRL---KIVPLAKVDCTANTN 89
Query: 309 VPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 440
+ Y V+G+PT+ + +Y+G R D ++ ++ ++
Sbjct: 90 TCNKYGVSGYPTLKIF--RAGEEAGAYDGPRTADGIVSHLKKQA 131
>sp|P11598|PDIA3_RAT Protein disulfide-isomerase A3 precursor (Disulfide isomerase
ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57)
(HIP-70) (Q-2)
Length = 505
Score = 193 bits (491), Expect = 3e-49
Identities = 91/149 (61%), Positives = 117/149 (78%), Gaps = 2/149 (1%)
Frame = +3
Query: 6 MAEDFTME--AFEKFINDFLNEQVPVYLKSETIPEKNDEPVKVVVAKNFDALVNDPTKDV 179
M E+F+ + A E+F+ ++ + + YLKSE IPE N+ PVKVVVA++FD +VN KDV
Sbjct: 338 MQEEFSRDGKALERFLQEYFDGNLKRYLKSEPIPETNEGPVKVVVAESFDDIVNAEDKDV 397
Query: 180 LIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDATANDVPSPYEVTGFPTIYFAP 359
LIEFYAPWCGHCK+L PKY+EL +KLS + +IVIAKMDATANDVPSPYEV GFPTIYF+P
Sbjct: 398 LIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVKGFPTIYFSP 457
Query: 360 KNSKNSPKSYNGGREVDDMLKYIASESTS 446
N K +PK Y GGRE++D + Y+ E+T+
Sbjct: 458 ANKKLTPKKYEGGRELNDFISYLQREATN 486
Score = 72.0 bits (175), Expect = 1e-12
Identities = 43/127 (33%), Positives = 73/127 (57%), Gaps = 3/127 (2%)
Frame = +3
Query: 69 VPVYLKSETIPEKNDEPVKVVVAKNFDALVNDPTKD--VLIEFYAPWCGHCKSLAPKYEE 242
V + L S + +D V + +NF++ V+D +L+EF+APWCGHCK LAP+YE
Sbjct: 12 VALLLASALLASASD--VLELTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEA 69
Query: 243 LAKKLSGESDIVIAKMDATAN-DVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDML 419
A +L G + +AK+D TAN + + Y V+G+PT+ + +Y+G R D ++
Sbjct: 70 AATRLKG--IVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAG--AYDGPRTADGIV 125
Query: 420 KYIASES 440
++ ++
Sbjct: 126 SHLKKQA 132
>sp|P38658|ERP60_SCHMA Probable protein disulfide-isomerase ER-60 precursor (ERP60)
Length = 484
Score = 189 bits (480), Expect = 5e-48
Identities = 86/161 (53%), Positives = 117/161 (72%)
Frame = +3
Query: 12 EDFTMEAFEKFINDFLNEQVPVYLKSETIPEKNDEPVKVVVAKNFDALVNDPTKDVLIEF 191
E F+++AF F+N F + + ++KSE +P + VK +VA NFD +VN+ KDV++ F
Sbjct: 324 EKFSLDAFSDFLNKFEDGLLTPHVKSEPLPTDDSSAVKKLVALNFDEIVNNEEKDVMVVF 383
Query: 192 YAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDATANDVPSPYEVTGFPTIYFAPKNSK 371
+A WCGHCK+L PKYEE A K+ E ++V+A MDATANDVPSPY+V GFPTIYF PK K
Sbjct: 384 HAGWCGHCKNLMPKYEEAASKVKNEPNLVLAAMDATANDVPSPYQVRGFPTIYFVPKGKK 443
Query: 372 NSPKSYNGGREVDDMLKYIASESTSSLKSYDRQGRVRKSDL 494
+SP SY GGR+ +D++KY+A E+T L YDR G +KS+L
Sbjct: 444 SSPVSYEGGRDTNDIIKYLAREATEELIGYDRSGNPKKSEL 484
Score = 67.4 bits (163), Expect = 3e-11
Identities = 32/89 (35%), Positives = 54/89 (60%), Gaps = 2/89 (2%)
Frame = +3
Query: 180 LIEFYAPWCGHCKSLAPKYEELAKKLSGE-SDIVIAKMDATAND-VPSPYEVTGFPTIYF 353
L++FYAPWCGHCK LAP++ A+ +SG+ +D+ + K+D T + + S + V+G+PT+
Sbjct: 38 LVKFYAPWCGHCKKLAPEFTSAAQIISGKTNDVKLVKVDCTTQESICSEFGVSGYPTLKI 97
Query: 354 APKNSKNSPKSYNGGREVDDMLKYIASES 440
+ YNG R + + Y+ S +
Sbjct: 98 FRNGDLDG--EYNGPRNANGIANYMISRA 124
>sp|P13667|PDIA4_HUMAN Protein disulfide-isomerase A4 precursor (Protein ERp-72) (ERp72)
Length = 645
Score = 161 bits (408), Expect = 1e-39
Identities = 77/146 (52%), Positives = 100/146 (68%), Gaps = 2/146 (1%)
Frame = +3
Query: 12 EDFTMEAFEKFINDFLNEQVPVYLKSETIPEKNDEPVKVVVAKNFDALVNDPTKDVLIEF 191
E+F + +F+ F ++ +KS+ +P+ N PVKVVV K FD++V DP KDVLIEF
Sbjct: 491 EEFDSDTLREFVTAFKKGKLKPVIKSQPVPKNNKGPVKVVVGKTFDSIVMDPKKDVLIEF 550
Query: 192 YAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDATANDVPSP-YEVTGFPTIYFAPKNS 368
YAPWCGHCK L P Y LAKK G+ +VIAKMDATANDVPS Y+V GFPTIYFAP
Sbjct: 551 YAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTIYFAPSGD 610
Query: 369 KNSPKSYNGG-REVDDMLKYIASEST 443
K +P + GG R+++ + K+I +T
Sbjct: 611 KKNPVKFEGGDRDLEHLSKFIEEHAT 636
Score = 92.8 bits (229), Expect = 6e-19
Identities = 51/111 (45%), Positives = 71/111 (63%), Gaps = 2/111 (1%)
Frame = +3
Query: 114 EPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSGES-DIVIAKM 290
E V+ +NFD +VND +L+EFYAPWCGHCK LAP+YE+ AK+LS S I +AK+
Sbjct: 177 EVTLVLTKENFDEVVND-ADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKV 235
Query: 291 DATA-NDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 440
DATA D+ ++V+G+PT+ K P YNG RE ++ Y+ +S
Sbjct: 236 DATAETDLAKRFDVSGYPTLKIF---RKGRPYDYNGpreKYGIVDYMIEQS 283
Score = 76.6 bits (187), Expect = 5e-14
Identities = 47/122 (38%), Positives = 70/122 (57%), Gaps = 3/122 (2%)
Frame = +3
Query: 84 KSETIPEKNDEPVKVVVAKNFDALVNDPTKD-VLIEFYAPWCGHCKSLAPKYEELAKKLS 260
+ + + K + V V+ NFD V D KD VL+EFYAPWCGHCK AP+YE++A L
Sbjct: 52 EEDDLEVKEENGVLVLNDANFDNFVAD--KDTVLLEFYAPWCGHCKQFAPEYEKIANILK 109
Query: 261 G-ESDIVIAKMDAT-ANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIAS 434
+ I +AK+DAT A+ + S ++V+G+PTI K Y G R ++++ +
Sbjct: 110 DKDPPIPVAKIDATSASVLASRFDVSGYPTIKIL---KKGQAVDYEGSRTQEEIVAKVRE 166
Query: 435 ES 440
S
Sbjct: 167 VS 168
>sp|P38659|PDIA4_RAT Protein disulfide-isomerase A4 precursor (Protein ERp-72) (ERp72)
(Calcium-binding protein 2) (CaBP2)
Length = 643
Score = 158 bits (400), Expect = 9e-39
Identities = 75/146 (51%), Positives = 101/146 (69%), Gaps = 2/146 (1%)
Frame = +3
Query: 12 EDFTMEAFEKFINDFLNEQVPVYLKSETIPEKNDEPVKVVVAKNFDALVNDPTKDVLIEF 191
E+F +A ++F+ F ++ +KS+ +P+ N PV+VVV K FDA+V DP KDVLIEF
Sbjct: 489 EEFDSDALQEFVMAFKKGKLKPVIKSQPVPKNNKGPVRVVVGKTFDAIVMDPKKDVLIEF 548
Query: 192 YAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDATANDVPSP-YEVTGFPTIYFAPKNS 368
YAPWCGHCK L P Y L KK G+ D+VIAKMDATAND+ + Y+V GFPTIYFAP
Sbjct: 549 YAPWCGHCKQLEPVYTSLGKKYKGQKDLVIAKMDATANDITNDRYKVEGFPTIYFAPSGD 608
Query: 369 KNSPKSYNGG-REVDDMLKYIASEST 443
K +P + GG R+++ + K+I +T
Sbjct: 609 KKNPIKFEGGNRDLEHLSKFIDEHAT 634
Score = 87.0 bits (214), Expect = 3e-17
Identities = 48/111 (43%), Positives = 69/111 (62%), Gaps = 2/111 (1%)
Frame = +3
Query: 114 EPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSGES-DIVIAKM 290
E + +NFD +VN+ +L+EFYAPWCGHCK LAP+YE+ AK+LS S I +AK+
Sbjct: 175 EVTLTLTKENFDDVVNN-ADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKV 233
Query: 291 DAT-ANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 440
DAT D+ ++V+G+PT+ K P YNG RE ++ Y+ +S
Sbjct: 234 DATEQTDLAKRFDVSGYPTLKIF---RKGRPFDYNGpreKYGIVDYMVEQS 281
Score = 79.3 bits (194), Expect = 7e-15
Identities = 47/115 (40%), Positives = 69/115 (60%), Gaps = 3/115 (2%)
Frame = +3
Query: 105 KNDEPVKVVVAKNFDALVNDPTKD-VLIEFYAPWCGHCKSLAPKYEELAKKL-SGESDIV 278
K + V V+ +NFD V D KD VL+EFYAPWCGHCK AP+YE++A L + I
Sbjct: 57 KEENGVWVLNDENFDNFVAD--KDTVLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIA 114
Query: 279 IAKMDAT-ANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 440
+AK+DAT A+ + S ++V+G+PTI K Y+G R ++++ + S
Sbjct: 115 VAKIDATSASMLASKFDVSGYPTIKIL---KKGQAVDYDGSRTQEEIVAKVREVS 166
>sp|P55059|PDI_HUMIN Protein disulfide-isomerase precursor (PDI)
Length = 505
Score = 158 bits (399), Expect = 1e-38
Identities = 78/143 (54%), Positives = 103/143 (72%), Gaps = 3/143 (2%)
Frame = +3
Query: 12 EDFTMEAFEKFINDFLNEQVPVYLKSETIPEKNDEPVKVVVAKNFDALVNDPTKDVLIEF 191
++ T EA + F++DF+ ++ +KSE IPEK + PV VVVAKN++ +V D TKDVLIEF
Sbjct: 321 KEITFEAIKAFVDDFVAGKIEPSIKSEPIPEKQEGPVTVVVAKNYNEIVLDDTKDVLIEF 380
Query: 192 YAPWCGHCKSLAPKYEELA---KKLSGESDIVIAKMDATANDVPSPYEVTGFPTIYFAPK 362
YAPWCGHCK+LAPKYEEL K + +VIAK+DATANDVP E+ GFPTI P
Sbjct: 381 YAPWCGHCKALAPKYEELGALYAKSEFKDRVVIAKVDATANDVPD--EIQGFPTIKLYPA 438
Query: 363 NSKNSPKSYNGGREVDDMLKYIA 431
+K P +Y+G R V+D++K+IA
Sbjct: 439 GAKGQPVTYSGSRTVEDLIKFIA 461
Score = 68.2 bits (165), Expect = 2e-11
Identities = 44/117 (37%), Positives = 64/117 (54%), Gaps = 3/117 (2%)
Frame = +3
Query: 177 VLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDAT-ANDVPSPYEVTGFPTIYF 353
VL EF+APWCGHCK+LAP+YEE A L E +I +AK+D T D+ + V G+PT+
Sbjct: 41 VLAEFFAPWCGHCKALAPEYEEAATTLK-EKNIKLAKVDCTEETDLCQQHGVEGYPTLKV 99
Query: 354 APKNSKNSPKSYNGGREVDDMLKYIASESTSSLK--SYDRQGRVRKSDL*KIKIVEY 518
SP Y G R+ + Y+ +S ++ + D +K+D K +V Y
Sbjct: 100 FRGLDNVSP--YKGQRKAAAITSYMIKQSLPAVSEVTKDNLEEFKKAD--KAVLVAY 152
>sp|P08003|PDIA4_MOUSE Protein disulfide-isomerase A4 precursor (Protein ERp-72) (ERp72)
Length = 638
Score = 157 bits (398), Expect = 2e-38
Identities = 75/146 (51%), Positives = 99/146 (67%), Gaps = 2/146 (1%)
Frame = +3
Query: 12 EDFTMEAFEKFINDFLNEQVPVYLKSETIPEKNDEPVKVVVAKNFDALVNDPTKDVLIEF 191
E+F + +F+ F ++ +KS+ +P+ N PVKVVV K FDA+V DP KDVLIEF
Sbjct: 484 EEFDSDTLREFVTAFKKGKLKPVIKSQPVPKNNKGPVKVVVGKTFDAIVMDPKKDVLIEF 543
Query: 192 YAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDATANDVPS-PYEVTGFPTIYFAPKNS 368
YAPWCGHCK L P Y L KK G+ D+VIAKMDATAND+ + Y+V GFPTIYFAP
Sbjct: 544 YAPWCGHCKQLEPIYTSLGKKYKGQKDLVIAKMDATANDITNDQYKVEGFPTIYFAPSGD 603
Query: 369 KNSPKSYNGG-REVDDMLKYIASEST 443
K +P + GG R+++ + K+I +T
Sbjct: 604 KKNPIKFEGGNRDLEHLSKFIDEHAT 629
Score = 85.9 bits (211), Expect = 8e-17
Identities = 47/102 (46%), Positives = 66/102 (64%), Gaps = 2/102 (1%)
Frame = +3
Query: 141 NFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSGES-DIVIAKMDAT-ANDVP 314
NFD +VN+ +L+EFYAPWCGHCK LAP+YE+ AK+LS S I +AK+DAT D+
Sbjct: 179 NFDDVVNN-ADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATEQTDLA 237
Query: 315 SPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 440
++V+G+PT+ K P YNG RE ++ Y+ +S
Sbjct: 238 KRFDVSGYPTLKIF---RKGRPFDYNGpreKYGIVDYMIEQS 276
Score = 78.2 bits (191), Expect = 2e-14
Identities = 47/115 (40%), Positives = 68/115 (59%), Gaps = 3/115 (2%)
Frame = +3
Query: 105 KNDEPVKVVVAKNFDALVNDPTKD-VLIEFYAPWCGHCKSLAPKYEELAKKL-SGESDIV 278
K + V V+ NFD V D KD VL+EFYAPWCGHCK AP+YE++A L + I
Sbjct: 52 KEENGVWVLNDGNFDNFVAD--KDTVLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIA 109
Query: 279 IAKMDAT-ANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 440
+AK+DAT A+ + S ++V+G+PTI K Y+G R ++++ + S
Sbjct: 110 VAKIDATSASMLASKFDVSGYPTIKIL---KKGQAVDYDGSRTQEEIVAKVREVS 161
>sp|P34329|PDIA4_CAEEL Probable protein disulfide-isomerase A4 precursor (ERp-72 homolog)
Length = 618
Score = 148 bits (374), Expect = 1e-35
Identities = 70/147 (47%), Positives = 94/147 (63%), Gaps = 1/147 (0%)
Frame = +3
Query: 27 EAFEKFINDFLNEQVPVYLKSETIPEKNDEPVKVVVAKNFDALVNDPTKDVLIEFYAPWC 206
E E F+ + + ++KS P+ + PVK VV NFD +VND +KDVLIEFYAPWC
Sbjct: 470 ENLEAFMKQISSGKAKAHVKSAPAPKDDKGPVKTVVGSNFDKIVNDESKDVLIEFYAPWC 529
Query: 207 GHCKSLAPKYEELAKKL-SGESDIVIAKMDATANDVPSPYEVTGFPTIYFAPKNSKNSPK 383
GHCKS KY ELA+ L + ++V+AKMDAT ND PS + V GFPTIYFAP K+ P
Sbjct: 530 GHCKSFESKYVELAQALKKTQPNVVLAKMDATINDAPSQFAVEGFPTIYFAPAGKKSEPI 589
Query: 384 SYNGGREVDDMLKYIASESTSSLKSYD 464
Y+G R+++D+ K++ S + D
Sbjct: 590 KYSGNRDLEDLKKFMTKHGVKSFQKKD 616
Score = 88.2 bits (217), Expect = 2e-17
Identities = 51/131 (38%), Positives = 80/131 (61%), Gaps = 5/131 (3%)
Frame = +3
Query: 78 YLKSETIPEKNDEPVKVVV--AKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAK 251
+++S P P +VV +NFD +++ + VL+EFYAPWCGHCK LAP+YE+ A+
Sbjct: 133 WVESRVDPNYKPPPEEVVTLTTENFDDFISN-NELVLVEFYAPWCGHCKKLAPEYEKAAQ 191
Query: 252 KLSGE-SDIVIAKMDAT-ANDVPSPYEVTGFPTIYFAPKNSKNSPK-SYNGGREVDDMLK 422
KL + S + + K+DAT D+ + Y V+G+PT+ K +N + YNG RE ++K
Sbjct: 192 KLKAQGSKVKLGKVDATIEKDLGTKYGVSGYPTM----KIIRNGRRFDYNGpreAAGIIK 247
Query: 423 YIASESTSSLK 455
Y+ +S + K
Sbjct: 248 YMTDQSKPAAK 258
Score = 86.7 bits (213), Expect = 4e-17
Identities = 48/116 (41%), Positives = 73/116 (62%), Gaps = 1/116 (0%)
Frame = +3
Query: 111 DEPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIAKM 290
DE V V+ KNFDA + VL++FYAPWCGHCK LAP+YE+ + K+S I +AK+
Sbjct: 35 DEGVVVLTDKNFDAFLKK-NPSVLVKFYAPWCGHCKHLAPEYEKASSKVS----IPLAKV 89
Query: 291 DATA-NDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASESTSSLK 455
DAT ++ +E+ G+PT+ F K+ K P Y+GGR+ +++++ S + K
Sbjct: 90 DATVETELGKRFEIQGYPTLKFW-KDGK-GPNDYDGGRDEAGIVEWVESRVDPNYK 143
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,764,341
Number of Sequences: 369166
Number of extensions: 1390818
Number of successful extensions: 4376
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4119
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4289
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 4877307000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)