Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_C04
(758 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P67962|KC1A_CHICK Casein kinase I, alpha isoform (CKI-al... 278 1e-74
sp|P48729|KC1A_HUMAN Casein kinase I, alpha isoform (CKI-al... 278 1e-74
sp|P67829|KC1A_SHEEP Casein kinase I, alpha isoform (CKI-al... 278 1e-74
sp|P97633|KC1A_RAT Casein kinase I, alpha isoform (CKI-alph... 278 1e-74
sp|Q8N752|KC1AL_HUMAN Casein kinase I, alpha-like isoform (... 271 2e-72
sp|P42168|YKL1_CAEEL Putative casein kinase I C03C10.1 in c... 267 2e-71
sp|P54367|KC1A_DROME Casein kinase I, alpha isoform (CKI-al... 262 8e-70
sp|Q06486|KC1D_RAT Casein kinase I, delta isoform (CKI-delt... 241 2e-63
sp|P48730|KC1D_HUMAN Casein kinase I, delta isoform (CKI-de... 241 2e-63
sp|P49674|KC1E_HUMAN Casein kinase I, epsilon isoform (CKI-... 240 3e-63
>sp|P67962|KC1A_CHICK Casein kinase I, alpha isoform (CKI-alpha) (CK1)
sp|P67963|KC1A_XENLA Casein kinase I, alpha isoform (CKI-alpha) (CK1)
Length = 337
Score = 278 bits (710), Expect = 1e-74
Identities = 131/178 (73%), Positives = 148/178 (83%)
Frame = +3
Query: 24 NFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYASINAHAGIEQSR 203
NFLMGIGRHCNKLF++DFGL+KKY+D +T+ HIPYREDKNLTGTARYASINAH GIEQSR
Sbjct: 141 NFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSR 200
Query: 204 RDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIEVLCKSFPPEFAFYL 383
RDDMES+GYV MYF R++LPWQGLKA KKQKYE+I EKK STP+EVLCK FP EFA YL
Sbjct: 201 RDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYL 260
Query: 384 EYCRNLKFDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLKQKAVGMQQQSHQCGGG 557
YCR L+F+EAP+Y LR+ F LFRTLN YDY FDWT+LKQKA QQ + G G
Sbjct: 261 NYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAA--QQAASSSGQG 316
>sp|P48729|KC1A_HUMAN Casein kinase I, alpha isoform (CKI-alpha) (CK1)
sp|Q8BK63|KC1A_MOUSE Casein kinase I, alpha isoform (CKI-alpha) (CK1)
Length = 337
Score = 278 bits (710), Expect = 1e-74
Identities = 131/178 (73%), Positives = 148/178 (83%)
Frame = +3
Query: 24 NFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYASINAHAGIEQSR 203
NFLMGIGRHCNKLF++DFGL+KKY+D +T+ HIPYREDKNLTGTARYASINAH GIEQSR
Sbjct: 141 NFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSR 200
Query: 204 RDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIEVLCKSFPPEFAFYL 383
RDDMES+GYV MYF R++LPWQGLKA KKQKYE+I EKK STP+EVLCK FP EFA YL
Sbjct: 201 RDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYL 260
Query: 384 EYCRNLKFDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLKQKAVGMQQQSHQCGGG 557
YCR L+F+EAP+Y LR+ F LFRTLN YDY FDWT+LKQKA QQ + G G
Sbjct: 261 NYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAA--QQAASSSGQG 316
>sp|P67829|KC1A_SHEEP Casein kinase I, alpha isoform (CKI-alpha) (CK1)
sp|P67828|KC1A_RABIT Casein kinase I, alpha isoform (CKI-alpha) (CK1)
sp|P67827|KC1A_BOVIN Casein kinase I, alpha isoform (CKI-alpha) (CK1)
Length = 325
Score = 278 bits (710), Expect = 1e-74
Identities = 131/178 (73%), Positives = 148/178 (83%)
Frame = +3
Query: 24 NFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYASINAHAGIEQSR 203
NFLMGIGRHCNKLF++DFGL+KKY+D +T+ HIPYREDKNLTGTARYASINAH GIEQSR
Sbjct: 141 NFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSR 200
Query: 204 RDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIEVLCKSFPPEFAFYL 383
RDDMES+GYV MYF R++LPWQGLKA KKQKYE+I EKK STP+EVLCK FP EFA YL
Sbjct: 201 RDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYL 260
Query: 384 EYCRNLKFDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLKQKAVGMQQQSHQCGGG 557
YCR L+F+EAP+Y LR+ F LFRTLN YDY FDWT+LKQKA QQ + G G
Sbjct: 261 NYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAA--QQAASSSGQG 316
>sp|P97633|KC1A_RAT Casein kinase I, alpha isoform (CKI-alpha) (CK1)
Length = 325
Score = 278 bits (710), Expect = 1e-74
Identities = 131/178 (73%), Positives = 148/178 (83%)
Frame = +3
Query: 24 NFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYASINAHAGIEQSR 203
NFLMGIGRHCNKLF++DFGL+KKY+D +T+ HIPYREDKNLTGTARYASINAH GIEQSR
Sbjct: 141 NFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSR 200
Query: 204 RDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIEVLCKSFPPEFAFYL 383
RDDMES+GYV MYF R++LPWQGLKA KKQKYE+I EKK STP+EVLCK FP EFA YL
Sbjct: 201 RDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYL 260
Query: 384 EYCRNLKFDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLKQKAVGMQQQSHQCGGG 557
YCR L+F+EAP+Y LR+ F LFRTLN YDY FDWT+LKQKA QQ + G G
Sbjct: 261 NYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAA--QQAASSSGQG 316
>sp|Q8N752|KC1AL_HUMAN Casein kinase I, alpha-like isoform (CKI-alpha-like) (CK1)
Length = 337
Score = 271 bits (692), Expect = 2e-72
Identities = 127/178 (71%), Positives = 145/178 (81%)
Frame = +3
Query: 24 NFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYASINAHAGIEQSR 203
NFLMG GRHCNKLF++DFGL+KKY+D +T+ HIPYREDK+L GT RYASINAH GIEQSR
Sbjct: 141 NFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYASINAHLGIEQSR 200
Query: 204 RDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIEVLCKSFPPEFAFYL 383
RDDMES+GYVFMYF R++LPWQGLKA KKQKYE+I EKK STP+EVLCK FP EFA YL
Sbjct: 201 RDDMESLGYVFMYFNRTSLPWQGLKAMTKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYL 260
Query: 384 EYCRNLKFDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLKQKAVGMQQQSHQCGGG 557
YCR L+F+E P+Y LR+ F LFRTLN YDY FDWT+LKQKA QQ + G G
Sbjct: 261 NYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAA--QQAASSSGQG 316
>sp|P42168|YKL1_CAEEL Putative casein kinase I C03C10.1 in chromosome III
Length = 341
Score = 267 bits (683), Expect = 2e-71
Identities = 128/179 (71%), Positives = 144/179 (80%)
Frame = +3
Query: 24 NFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYASINAHAGIEQSR 203
NFLMGIGRHCNKLF++DFGL+KKY+D++T+ HIPYREDKNLTGTARYASINAH GIEQSR
Sbjct: 140 NFLMGIGRHCNKLFLIDFGLAKKYRDSRTRTHIPYREDKNLTGTARYASINAHLGIEQSR 199
Query: 204 RDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIEVLCKSFPPEFAFYL 383
RDDMES+GYV MYF R TLPWQGLKA KKQKYE+I EKK +T +E LCK FP EF YL
Sbjct: 200 RDDMESLGYVLMYFNRGTLPWQGLKAATKKQKYEKISEKKMTTSVEHLCKGFPAEFPMYL 259
Query: 384 EYCRNLKFDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLKQKAVGMQQQSHQCGGGG 560
Y R L+FDE+P+Y LR+ F LFRTLN YDY FDWT+LKQKA QQS G G
Sbjct: 260 SYTRGLRFDESPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKA----QQSQSSGVPG 314
>sp|P54367|KC1A_DROME Casein kinase I, alpha isoform (CKI-alpha) (DmCK1)
Length = 337
Score = 262 bits (669), Expect = 8e-70
Identities = 120/164 (73%), Positives = 139/164 (84%)
Frame = +3
Query: 24 NFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYASINAHAGIEQSR 203
NFLMGIGRHCNKLF++DFGL+KK++D T+ HI YREDKNLTGTARYASINAH GIEQSR
Sbjct: 144 NFLMGIGRHCNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYASINAHLGIEQSR 203
Query: 204 RDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIEVLCKSFPPEFAFYL 383
RDDMES+GYV MYF R LPWQG+KAN K+QKYE+I EKK STPIEVLCK P EF+ YL
Sbjct: 204 RDDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKGSPAEFSMYL 263
Query: 384 EYCRNLKFDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLKQK 515
YCR+L+F+E P+Y LR+ F LFRTLN YDY++DWT+LKQK
Sbjct: 264 NYCRSLRFEEQPDYMYLRQLFRILFRTLNHQYDYIYDWTMLKQK 307
>sp|Q06486|KC1D_RAT Casein kinase I, delta isoform (CKI-delta)
sp|Q9DC28|KC1D_MOUSE Casein kinase I, delta isoform (CKI-delta) (CKId)
Length = 415
Score = 241 bits (615), Expect = 2e-63
Identities = 109/162 (67%), Positives = 132/162 (81%)
Frame = +3
Query: 24 NFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYASINAHAGIEQSR 203
NFLMG+G+ N ++++DFGL+KKY+D +T HIPYRE+KNLTGTARYASIN H GIEQSR
Sbjct: 133 NFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSR 192
Query: 204 RDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIEVLCKSFPPEFAFYL 383
RDD+ES+GYV MYF +LPWQGLKA K+QKYERI EKK STPIEVLCK +P EFA YL
Sbjct: 193 RDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYL 252
Query: 384 EYCRNLKFDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLK 509
+CR+L+FD+ P+Y LR+ F NLF F+YDYVFDW +LK
Sbjct: 253 NFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLK 294
>sp|P48730|KC1D_HUMAN Casein kinase I, delta isoform (CKI-delta) (CKId)
Length = 415
Score = 241 bits (615), Expect = 2e-63
Identities = 109/162 (67%), Positives = 132/162 (81%)
Frame = +3
Query: 24 NFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYASINAHAGIEQSR 203
NFLMG+G+ N ++++DFGL+KKY+D +T HIPYRE+KNLTGTARYASIN H GIEQSR
Sbjct: 133 NFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSR 192
Query: 204 RDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIEVLCKSFPPEFAFYL 383
RDD+ES+GYV MYF +LPWQGLKA K+QKYERI EKK STPIEVLCK +P EFA YL
Sbjct: 193 RDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYL 252
Query: 384 EYCRNLKFDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLK 509
+CR+L+FD+ P+Y LR+ F NLF F+YDYVFDW +LK
Sbjct: 253 NFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLK 294
>sp|P49674|KC1E_HUMAN Casein kinase I, epsilon isoform (CKI-epsilon) (CKIe)
Length = 416
Score = 240 bits (612), Expect = 3e-63
Identities = 108/162 (66%), Positives = 132/162 (81%)
Frame = +3
Query: 24 NFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYASINAHAGIEQSR 203
NFLMG+G+ N ++++DFGL+KKY+D +T HIPYRE+KNLTGTARYASIN H GIEQSR
Sbjct: 133 NFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSR 192
Query: 204 RDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIEVLCKSFPPEFAFYL 383
RDD+ES+GYV MYF +LPWQGLKA K+QKYERI EKK STPIEVLCK +P EF+ YL
Sbjct: 193 RDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYL 252
Query: 384 EYCRNLKFDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLK 509
+CR+L+FD+ P+Y LR+ F NLF F+YDYVFDW +LK
Sbjct: 253 NFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLK 294
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,790,497
Number of Sequences: 369166
Number of extensions: 1785289
Number of successful extensions: 5303
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5071
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5280
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6970118400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)