Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_B05
(760 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P27615|SCRB2_RAT Lysosome membrane protein II (LIMP II) ... 157 3e-38
sp|Q14108|SCRB2_HUMAN Lysosome membrane protein II (LIMP II... 155 1e-37
sp|O35114|SCRB2_MOUSE Lysosome membrane protein II (LIMP II... 150 4e-36
sp|P97943|SCRB1_RAT Scavenger receptor class B member 1 (SR... 136 5e-32
sp|P70110|CD36_MESAU Platelet glycoprotein IV (GPIV) (GPIII... 135 9e-32
sp|P16671|CD36_HUMAN Platelet glycoprotein IV (GPIV) (Glyco... 134 3e-31
sp|Q61009|SCRB1_MOUSE Scavenger receptor class B member 1 (... 133 6e-31
sp|Q60417|SCRB1_CRIGR Scavenger receptor class B member 1 (... 132 1e-30
sp|Q08857|CD36_MOUSE Platelet glycoprotein IV (GPIV) (GPIII... 130 3e-30
sp|Q07969|CD36_RAT Platelet glycoprotein IV (GPIV) (GPIIIB)... 128 2e-29
>sp|P27615|SCRB2_RAT Lysosome membrane protein II (LIMP II) (Scavenger receptor class B
member 2) (85 kDa lysosomal membrane sialoglycoprotein)
(LGP85) (CD36 antigen-like 2)
Length = 478
Score = 157 bits (397), Expect = 3e-38
Identities = 80/184 (43%), Positives = 119/184 (64%), Gaps = 2/184 (1%)
Frame = +2
Query: 5 FAPYLNRSSRLYIFQSDICRSIYATYVGSEEIKGVPSMNYAAPDSVFANHSVNPDNEGFC 184
F P +++ LYIF SD CRS+Y T+ E ++G+P+ Y P + AN S +N GFC
Sbjct: 256 FHPLISKDETLYIFPSDFCRSVYITFSSFENVEGLPAFRYKVPAEILANSS---ENAGFC 312
Query: 185 L-DGDCMGAGVLNLSKCVPGGAPIIMSQPHFYSAAEKYIDAVYGINPSSE-FKTILKLEP 358
+ +G+CM AGVLN+S C GAPIIMS PHFY A EK++ A+ G+ P+ E ++ + + P
Sbjct: 313 IPEGNCMDAGVLNVSIC-KNGAPIIMSFPHFYQADEKFVSAIKGMRPNKEEHESFVDINP 371
Query: 359 TTGLPLQLAKKLQINIAIKPVKDFFKMDNISSVVLPMMWLNESVLISDALAGTIRSTLVL 538
TG+ L+ AK+ QIN +K + DF + NI ++V P+M+LNESVLI A ++S +
Sbjct: 372 LTGIILRGAKRFQINTYVKKLDDFVETGNIRTMVFPVMYLNESVLIDKETASQLKSVINT 431
Query: 539 PVLV 550
++V
Sbjct: 432 TLIV 435
>sp|Q14108|SCRB2_HUMAN Lysosome membrane protein II (LIMP II) (Scavenger receptor class B
member 2) (85 kDa lysosomal membrane sialoglycoprotein)
(LGP85) (CD36 antigen-like 2)
Length = 478
Score = 155 bits (392), Expect = 1e-37
Identities = 77/184 (41%), Positives = 120/184 (65%), Gaps = 2/184 (1%)
Frame = +2
Query: 5 FAPYLNRSSRLYIFQSDICRSIYATYVGSEEIKGVPSMNYAAPDSVFANHSVNPDNEGFC 184
F P + + LY+F SD CRS+Y T+ E ++G+P+ Y P + AN S DN GFC
Sbjct: 256 FHPLITKDEVLYVFPSDFCRSVYITFSDYESVQGLPAFRYKVPAEILANTS---DNAGFC 312
Query: 185 L-DGDCMGAGVLNLSKCVPGGAPIIMSQPHFYSAAEKYIDAVYGINPSSE-FKTILKLEP 358
+ +G+C+G+GVLN+S C GAPIIMS PHFY A E+++ A+ G++P+ E +T + + P
Sbjct: 313 IPEGNCLGSGVLNVSIC-KNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFVDINP 371
Query: 359 TTGLPLQLAKKLQINIAIKPVKDFFKMDNISSVVLPMMWLNESVLISDALAGTIRSTLVL 538
TG+ L+ AK+ QINI +K + DF + +I ++V P+M+LNESV I A ++S +
Sbjct: 372 LTGIILKAAKRFQINIYVKKLDDFVETGDIRTMVFPVMYLNESVHIDKETASRLKSMINT 431
Query: 539 PVLV 550
+++
Sbjct: 432 TLII 435
>sp|O35114|SCRB2_MOUSE Lysosome membrane protein II (LIMP II) (Scavenger receptor class B
member 2) (85 kDa lysosomal membrane sialoglycoprotein)
(LGP85)
Length = 478
Score = 150 bits (379), Expect = 4e-36
Identities = 75/184 (40%), Positives = 121/184 (65%), Gaps = 2/184 (1%)
Frame = +2
Query: 5 FAPYLNRSSRLYIFQSDICRSIYATYVGSEEIKGVPSMNYAAPDSVFANHSVNPDNEGFC 184
F P +++ LY+F SD+CRS++ T+ E ++G+P+ Y P + AN S +N GFC
Sbjct: 256 FHPLISKDEVLYLFPSDLCRSVHITFSSFENVEGLPAFRYKVPAEILANTS---ENAGFC 312
Query: 185 L-DGDCMGAGVLNLSKCVPGGAPIIMSQPHFYSAAEKYIDAVYGINPSSE-FKTILKLEP 358
+ +G+CM +GVLN+S C GAPIIMS PHFY A EK++ A+ G++P+ E ++ + + P
Sbjct: 313 IPEGNCMDSGVLNISIC-KNGAPIIMSFPHFYQADEKFVSAIKGMHPNKEEHESFVDINP 371
Query: 359 TTGLPLQLAKKLQINIAIKPVKDFFKMDNISSVVLPMMWLNESVLISDALAGTIRSTLVL 538
TG+ L+ AK+ QIN ++ + DF + +I ++V P+M+LNESVLI A ++S +
Sbjct: 372 LTGIILRGAKRFQINTYVRKLDDFVETGDIRTMVFPVMYLNESVLIDKETANQLKSVINT 431
Query: 539 PVLV 550
++V
Sbjct: 432 TLVV 435
>sp|P97943|SCRB1_RAT Scavenger receptor class B member 1 (SRB1) (SR-BI)
Length = 509
Score = 136 bits (343), Expect = 5e-32
Identities = 71/180 (39%), Positives = 105/180 (58%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 MFAPYLNRSSRLYIFQSDICRSIYATYVGSEEIKGVPSMNYAAPDSVFANHSVNPDNEGF 181
M+AP++ S L F + CRS+ TY S +G+P+ + APD++FAN SV P NEGF
Sbjct: 261 MWAPFMTPESSLEFFSPEACRSMKLTYQESRVFEGIPTYRFTAPDTLFANGSVYPPNEGF 320
Query: 182 CLDGDCMGAGVLNLSKCVPGGAPIIMSQPHFYSAAEKYIDAVYGINPS-SEFKTILKLEP 358
C C +G+ N+S C GAP+ +SQPHFY+A +AV G+NP E L + P
Sbjct: 321 C---PCRESGIQNVSTC-RFGAPLFLSQPHFYNADPVLSEAVLGLNPDPKEHSLFLDIHP 376
Query: 359 TTGLPLQLAKKLQINIAIKPVKDFFKMDNISSVVLPMMWLNESVLISDALAGTIRSTLVL 538
TG+P+ + K+Q+++ IK VK + I VVLP++W +S ++ T + LVL
Sbjct: 377 VTGIPMNCSVKMQLSLYIKSVKGVGQTGKIEPVVLPLLWFEQSGMMGGKTLNTFYTQLVL 436
>sp|P70110|CD36_MESAU Platelet glycoprotein IV (GPIV) (GPIIIB) (CD36 antigen) (PAS IV)
(PAS-4 protein)
Length = 472
Score = 135 bits (341), Expect = 9e-32
Identities = 71/180 (39%), Positives = 105/180 (58%), Gaps = 6/180 (3%)
Frame = +2
Query: 5 FAPYLNRSSRLYIFQSDICRSIYATYVGSEEIKGVPSMNYAAPDSVFANHSVNPDNEGFC 184
F P++ +S L F SDICRSIYA + E+KG+P + P FA+ NPDN FC
Sbjct: 254 FPPFVEKSRVLRFFSSDICRSIYAVFGSDIELKGIPVYRFILPAKAFASPVQNPDNHCFC 313
Query: 185 ----LDGDCMGAGVLNLSKCVPGGAPIIMSQPHFYSAAEKYIDAVYGINPS-SEFKTILK 349
+ +C GVL++SKC G P+ +S PHF A+ + + G+NP+ E +T L
Sbjct: 314 TEKVISNNCTSYGVLDISKC-KQGRPVYISLPHFLHASPDISEPIEGLNPNEEEHRTYLD 372
Query: 350 LEPTTGLPLQLAKKLQINIAIKPVKDFFKMDNIS-SVVLPMMWLNESVLISDALAGTIRS 526
+EP TG LQ AK+LQ+NI +KP + + N+ + ++P++WLNE+ I D A R+
Sbjct: 373 VEPITGFTLQFAKRLQVNILVKPARKIEALKNLKRNYIVPILWLNETGTIGDEKAEMFRN 432
>sp|P16671|CD36_HUMAN Platelet glycoprotein IV (GPIV) (Glycoprotein IIIb) (GPIIIB)
(Leukocyte differentiation antigen CD36) (CD36 antigen)
(PAS IV) (PAS-4 protein) (Platelet collagen receptor)
(Fatty acid translocase) (FAT) (Thrombospondin receptor)
Length = 472
Score = 134 bits (337), Expect = 3e-31
Identities = 70/180 (38%), Positives = 104/180 (57%), Gaps = 6/180 (3%)
Frame = +2
Query: 5 FAPYLNRSSRLYIFQSDICRSIYATYVGSEEIKGVPSMNYAAPDSVFANHSVNPDNEGFC 184
F P++ +S L F SDICRSIYA + +KG+P + P FA+ NPDN FC
Sbjct: 254 FPPFVEKSQVLQFFSSDICRSIYAVFESDVNLKGIPVYRFVLPSKAFASPVENPDNYCFC 313
Query: 185 ----LDGDCMGAGVLNLSKCVPGGAPIIMSQPHFYSAAEKYIDAVYGINPS-SEFKTILK 349
+ +C GVL++SKC G P+ +S PHF A+ + + G+NP+ E +T L
Sbjct: 314 TEKIISKNCTSYGVLDISKC-KEGRPVYISLPHFLYASPDVSEPIDGLNPNEEEHRTYLD 372
Query: 350 LEPTTGLPLQLAKKLQINIAIKPVKDFFKMDNIS-SVVLPMMWLNESVLISDALAGTIRS 526
+EP TG LQ AK+LQ+N+ +KP + + N+ + ++P++WLNE+ I D A RS
Sbjct: 373 IEPITGFTLQFAKRLQVNLLVKPSEKIQVLKNLKRNYIVPILWLNETGTIGDEKANMFRS 432
>sp|Q61009|SCRB1_MOUSE Scavenger receptor class B member 1 (SRB1) (SR-BI)
Length = 509
Score = 133 bits (334), Expect = 6e-31
Identities = 70/180 (38%), Positives = 104/180 (57%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 MFAPYLNRSSRLYIFQSDICRSIYATYVGSEEIKGVPSMNYAAPDSVFANHSVNPDNEGF 181
M+AP++ S L F + CRS+ TY S +G+P+ + APD++FAN SV P NEGF
Sbjct: 261 MWAPFMTPESSLEFFSPEACRSMKLTYNESRVFEGIPTYRFTAPDTLFANGSVYPPNEGF 320
Query: 182 CLDGDCMGAGVLNLSKCVPGGAPIIMSQPHFYSAAEKYIDAVYGINPS-SEFKTILKLEP 358
C C +G+ N+S C GAP+ +S PHFY+A +AV G+NP+ E L + P
Sbjct: 321 C---PCRESGIQNVSTC-RFGAPLFLSHPHFYNADPVLSEAVLGLNPNPKEHSLFLDIHP 376
Query: 359 TTGLPLQLAKKLQINIAIKPVKDFFKMDNISSVVLPMMWLNESVLISDALAGTIRSTLVL 538
TG+P+ + K+Q+++ IK VK + I VVLP++W +S + T + LVL
Sbjct: 377 VTGIPMNCSVKMQLSLYIKSVKGIGQTGKIEPVVLPLLWFEQSGAMGGKPLSTFYTQLVL 436
>sp|Q60417|SCRB1_CRIGR Scavenger receptor class B member 1 (SRB1) (SR-BI) (HaSR-BI)
Length = 509
Score = 132 bits (331), Expect = 1e-30
Identities = 71/180 (39%), Positives = 103/180 (57%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 MFAPYLNRSSRLYIFQSDICRSIYATYVGSEEIKGVPSMNYAAPDSVFANHSVNPDNEGF 181
M+AP++ S L F + CRS+ TY S +G+P+ + AP ++FAN SV P NEGF
Sbjct: 261 MWAPFMTPQSSLEFFSPEACRSMKLTYHDSGVFEGIPTYRFTAPKTLFANGSVYPPNEGF 320
Query: 182 CLDGDCMGAGVLNLSKCVPGGAPIIMSQPHFYSAAEKYIDAVYGINPS-SEFKTILKLEP 358
C C+ +G+ N+S C GAP+ +S PHFY+A +AV G+NP E L + P
Sbjct: 321 C---PCLESGIQNVSTC-RFGAPLFLSHPHFYNADPVLSEAVLGLNPDpreHSLFLDIHP 376
Query: 359 TTGLPLQLAKKLQINIAIKPVKDFFKMDNISSVVLPMMWLNESVLISDALAGTIRSTLVL 538
TG+P+ + KLQI++ IK VK + I VVLP++W +S + T + LVL
Sbjct: 377 VTGIPMNCSVKLQISLYIKAVKGIGQTGKIEPVVLPLLWFEQSGAMGGEPLNTFYTQLVL 436
>sp|Q08857|CD36_MOUSE Platelet glycoprotein IV (GPIV) (GPIIIB) (CD36 antigen) (PAS IV)
(PAS-4 protein)
Length = 472
Score = 130 bits (328), Expect = 3e-30
Identities = 67/175 (38%), Positives = 102/175 (58%), Gaps = 6/175 (3%)
Frame = +2
Query: 5 FAPYLNRSSRLYIFQSDICRSIYATYVGSEEIKGVPSMNYAAPDSVFANHSVNPDNEGFC 184
F P++ +S L F SDICRSIYA + ++KG+P + P + FA+ NPDN FC
Sbjct: 254 FPPFVEKSRTLRFFSSDICRSIYAVFGSEIDLKGIPVYRFVLPANAFASPLQNPDNHCFC 313
Query: 185 ----LDGDCMGAGVLNLSKCVPGGAPIIMSQPHFYSAAEKYIDAVYGINPS-SEFKTILK 349
+ +C GVL++ KC G P+ +S PHF A+ + + G++P+ E +T L
Sbjct: 314 TEKVISNNCTSYGVLDIGKC-KEGKPVYISLPHFLHASPDVSEPIEGLHPNEDEHRTYLD 372
Query: 350 LEPTTGLPLQLAKKLQINIAIKPVKDFFKMDNIS-SVVLPMMWLNESVLISDALA 511
+EP TG LQ AK+LQ+NI +KP + + N+ ++P++WLNE+ I D A
Sbjct: 373 VEPITGFTLQFAKRLQVNILVKPARKIEALKNLKRPYIVPILWLNETGTIGDEKA 427
>sp|Q07969|CD36_RAT Platelet glycoprotein IV (GPIV) (GPIIIB) (CD36 antigen) (PAS IV)
(PAS-4 protein) (Fatty acid transport protein) (Fatty
acid translocase) (Adipocyte membrane protein)
Length = 472
Score = 128 bits (321), Expect = 2e-29
Identities = 68/180 (37%), Positives = 100/180 (55%), Gaps = 6/180 (3%)
Frame = +2
Query: 5 FAPYLNRSSRLYIFQSDICRSIYATYVGSEEIKGVPSMNYAAPDSVFANHSVNPDNEGFC 184
F P +S L F SDICRSIYA + +KG+P + P + FA+ NPDN FC
Sbjct: 254 FPPLGEKSRTLRFFSSDICRSIYAVFESEVNLKGIPVYRFVLPANAFASPLQNPDNHCFC 313
Query: 185 ----LDGDCMGAGVLNLSKCVPGGAPIIMSQPHFYSAAEKYIDAVYGINPS-SEFKTILK 349
+ +C GVL++ KC G P+ S PHF A+ + + G+NP+ E +T L
Sbjct: 314 TEKVISNNCTSYGVLDIGKC-KEGKPVYNSLPHFLHASPDVSEPIEGLNPTEDEHRTYLD 372
Query: 350 LEPTTGLPLQLAKKLQINIAIKPVKDFFKMDNIS-SVVLPMMWLNESVLISDALAGTIRS 526
+EP TG LQ +K+LQ+NI +KP + + N+ ++P++WLNE+ I D A R+
Sbjct: 373 VEPITGFTLQFSKRLQVNILVKPARKIEALKNLKRPYIVPILWLNETGTIGDEKAEMFRN 432
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,960,516
Number of Sequences: 369166
Number of extensions: 2013395
Number of successful extensions: 6179
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5847
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6116
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6970118400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)