Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_B02
(886 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q80XJ3|K1043_MOUSE TPR repeat-containing protein KIAA1043 44 6e-04
sp|Q96AY4|K1043_HUMAN TPR repeat-containing protein KIAA1043 44 8e-04
sp|P81274|GPSM2_HUMAN G-protein signalling modulator 2 (Mos... 40 0.011
sp|P94415|RAPC_BACSU Response regulator aspartate phosphata... 39 0.015
sp|Q8VDU0|GPSM2_MOUSE G-protein signalling modulator 2 (Pin... 37 0.096
sp|O06917|Y263_METJA Hypothetical protein MJ0263 36 0.12
sp|P49321|NASP_HUMAN Nuclear autoantigenic sperm protein (N... 36 0.16
sp|P27123|NASP_RABIT Nuclear autoantigenic sperm protein (N... 36 0.16
sp|P06180|HIBN_XENLA Histone-binding protein N1/N2 34 0.62
sp|Q6Q4D0|BRU1_ARATH BRUSHY protein 1 (TONSOKU protein) (MG... 34 0.62
>sp|Q80XJ3|K1043_MOUSE TPR repeat-containing protein KIAA1043
Length = 1691
Score = 43.9 bits (102), Expect = 6e-04
Identities = 26/113 (23%), Positives = 52/113 (46%)
Frame = +2
Query: 527 EMTQKISYLREALDYAREGEKKKLQGKCSYKLGMAYQEADKPDVAINYLMQYYNISKSIN 706
E + Y + L A E + QG+ LG+ Y+ + A+ Y Q+ +I+ +N
Sbjct: 247 EYDTALQYHQLDLQIAEETDNPTCQGRAYGNLGLTYESLGTFERAVVYQEQHLSIAAQMN 306
Query: 707 DDENFCIACDALAKVFRSQKKYEECIKYLEEFAECAERSLQKEAHSQACRALG 865
D ++ +L + + + Y + + YL+E AE+ ++E ++ LG
Sbjct: 307 DLVAKTVSYSSLGRTHHALQNYSQAVMYLQEGLRLAEQLGRREDEAKIRHGLG 359
Score = 36.6 bits (83), Expect = 0.096
Identities = 26/121 (21%), Positives = 54/121 (44%), Gaps = 3/121 (2%)
Frame = +2
Query: 533 TQKISYLREALDYAREGEKKKLQGKCSYKLGMAYQEADKPDVAINYLMQYYNISKSINDD 712
T +E L+ R+ ++ L+ + +G+ + + AI Y Q + + ++ +
Sbjct: 46 TMAFKCYQEQLELGRKLKEPSLEAQVYGNMGITKMNMNVMEDAIGYFEQQLAMLQQLSGN 105
Query: 713 ENFCI---ACDALAKVFRSQKKYEECIKYLEEFAECAERSLQKEAHSQACRALGDVYNHL 883
E+ A L + + YEE IKY E++ A+ + + ++A R LG+ +
Sbjct: 106 ESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQSLNRMQDQAKAYRGLGNGHRAT 165
Query: 884 G 886
G
Sbjct: 166 G 166
>sp|Q96AY4|K1043_HUMAN TPR repeat-containing protein KIAA1043
Length = 1716
Score = 43.5 bits (101), Expect = 8e-04
Identities = 26/113 (23%), Positives = 51/113 (45%)
Frame = +2
Query: 527 EMTQKISYLREALDYAREGEKKKLQGKCSYKLGMAYQEADKPDVAINYLMQYYNISKSIN 706
E + Y + L A E QG+ LG+ Y+ + A+ Y Q+ +I+ +N
Sbjct: 247 EYDTALQYHQLDLQIAEETNNPTCQGRAYGNLGLTYESLGTFERAVVYQEQHLSIAAQMN 306
Query: 707 DDENFCIACDALAKVFRSQKKYEECIKYLEEFAECAERSLQKEAHSQACRALG 865
D ++ +L + + + Y + + YL+E AE+ ++E ++ LG
Sbjct: 307 DLAAKTVSYSSLGRTHHALQNYSQAVMYLQEGLRLAEQLGRREDEAKIRHGLG 359
Score = 37.0 bits (84), Expect = 0.073
Identities = 26/121 (21%), Positives = 53/121 (43%), Gaps = 3/121 (2%)
Frame = +2
Query: 533 TQKISYLREALDYAREGEKKKLQGKCSYKLGMAYQEADKPDVAINYLMQYYNISKSINDD 712
T E LD ++ + L+ + +G+ + + AI Y Q + + ++ +
Sbjct: 46 TMAFKCYEEQLDLGQKLKDPSLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAMLQQLSGN 105
Query: 713 ENFCI---ACDALAKVFRSQKKYEECIKYLEEFAECAERSLQKEAHSQACRALGDVYNHL 883
E+ A L + + YEE IKY E++ A+ + + ++A R LG+ + +
Sbjct: 106 ESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQSLNRMQDQAKAYRGLGNGHRAM 165
Query: 884 G 886
G
Sbjct: 166 G 166
>sp|P81274|GPSM2_HUMAN G-protein signalling modulator 2 (Mosaic protein LGN)
Length = 677
Score = 39.7 bits (91), Expect = 0.011
Identities = 31/144 (21%), Positives = 62/144 (43%)
Frame = +2
Query: 455 EACEHLSNIRLEMSESFLDNFKNIEMTQKISYLREALDYAREGEKKKLQGKCSYKLGMAY 634
+A E + L + FL F+ Y ++ L AR+ + + ++ + Y LG Y
Sbjct: 231 KAAERRAYSNLGNAYIFLGEFETAS-----EYYKKTLLLARQLKDRAVEAQSCYSLGNTY 285
Query: 635 QEADKPDVAINYLMQYYNISKSINDDENFCIACDALAKVFRSQKKYEECIKYLEEFAECA 814
+ AI+Y +++ I++ +ND AC +L + + +++ + + E+ E +
Sbjct: 286 TLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEIS 345
Query: 815 ERSLQKEAHSQACRALGDVYNHLG 886
K A L D+ LG
Sbjct: 346 REVGDKSGELTARLNLSDLQMVLG 369
Score = 36.2 bits (82), Expect = 0.12
Identities = 28/127 (22%), Positives = 54/127 (42%)
Frame = +2
Query: 506 LDNFKNIEMTQKISYLREALDYAREGEKKKLQGKCSYKLGMAYQEADKPDVAINYLMQYY 685
L NF++ + + + L A+E K + + LG AY + + A Y +
Sbjct: 208 LGNFRDAVIAHE-----QRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTL 262
Query: 686 NISKSINDDENFCIACDALAKVFRSQKKYEECIKYLEEFAECAERSLQKEAHSQACRALG 865
+++ + D +C +L + + YE+ I Y + A+ + +AC +LG
Sbjct: 263 LLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLG 322
Query: 866 DVYNHLG 886
+ Y LG
Sbjct: 323 NAYTALG 329
>sp|P94415|RAPC_BACSU Response regulator aspartate phosphatase C
Length = 382
Score = 39.3 bits (90), Expect = 0.015
Identities = 46/219 (21%), Positives = 88/219 (40%), Gaps = 2/219 (0%)
Frame = +2
Query: 173 DYKGMYHSYFRLANFFKS-YPEDKWLVDHFFKYCWSVSKKIND-DENLKHAEANYYLGLA 346
D KG+ Y NFF+ Y DK Y KK++ ++++ AE + + A
Sbjct: 95 DLKGLLDYY---VNFFRGMYEFDKREFISAITYYKQAEKKLSFVADHIERAEFYFKIAEA 151
Query: 347 IELNKDYEEAFQYFHTLYTLSKKQTWKNEHNVLLFIEACEHLSNIRLEMSESFLDNFKNI 526
K YF + + + + + + I C + + L +F
Sbjct: 152 YYYMKQ-----TYFSLINIKNAYEIYVEQETYNVRIIQCHFVFGVNLMDERNF------- 199
Query: 527 EMTQKISYLREALDYAREGEKKKLQGKCSYKLGMAYQEADKPDVAINYLMQYYNISKSIN 706
Q + + AL+ A+ +K +L G+ Y LG+ Y D D AI+Y + + +S
Sbjct: 200 --EQAARHFKLALNMAQAEQKAQLVGRAYYNLGLCYYNQDLLDPAIDYFEKAVSTFESSR 257
Query: 707 DDENFCIACDALAKVFRSQKKYEECIKYLEEFAECAERS 823
+ A + ++ Q K+++ +Y + E A+ +
Sbjct: 258 IVNSLPQAYFLITLIYYKQGKHDKASEYHKRGYEYAKET 296
>sp|Q8VDU0|GPSM2_MOUSE G-protein signalling modulator 2 (Pins homolog)
Length = 672
Score = 36.6 bits (83), Expect = 0.096
Identities = 28/127 (22%), Positives = 54/127 (42%)
Frame = +2
Query: 506 LDNFKNIEMTQKISYLREALDYAREGEKKKLQGKCSYKLGMAYQEADKPDVAINYLMQYY 685
L NF++ + + + L A+E K + + LG AY + + A Y +
Sbjct: 208 LGNFRDAVIAHE-----QRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTL 262
Query: 686 NISKSINDDENFCIACDALAKVFRSQKKYEECIKYLEEFAECAERSLQKEAHSQACRALG 865
+++ + D +C +L + + YE+ I Y + A+ + +AC +LG
Sbjct: 263 LLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELKDRIGEGRACWSLG 322
Query: 866 DVYNHLG 886
+ Y LG
Sbjct: 323 NAYTALG 329
>sp|O06917|Y263_METJA Hypothetical protein MJ0263
Length = 320
Score = 36.2 bits (82), Expect = 0.12
Identities = 42/165 (25%), Positives = 63/165 (38%), Gaps = 16/165 (9%)
Frame = +2
Query: 362 DYEEAFQYFHTLYTLSKKQTWKNEHNVLLFIEACEHLSNIRLEMSESFLDNFKNIE--MT 535
+YE +Y L LSK H L++IE E LE + FL + N+ +
Sbjct: 95 EYERTLKYIEKLSRLSKPCYLSPFHKALIYIEFGEF--EKALEALDEFLKIYPNLTSILR 152
Query: 536 QKISYLR------EALDYAR--------EGEKKKLQGKCSYKLGMAYQEADKPDVAINYL 673
QK S L EALD + L+G+ KLG + D +AIN
Sbjct: 153 QKASILEILGKLDEALDCVNKILSIKKDDAHAWYLKGRILKKLGNIKEALDALKMAINL- 211
Query: 674 MQYYNISKSINDDENFCIACDALAKVFRSQKKYEECIKYLEEFAE 808
+EN +A + + YEE + Y+ ++ E
Sbjct: 212 ------------NENLVHVYKDIAYLELANNNYEEALNYITKYLE 244
>sp|P49321|NASP_HUMAN Nuclear autoantigenic sperm protein (NASP)
Length = 788
Score = 35.8 bits (81), Expect = 0.16
Identities = 38/185 (20%), Positives = 74/185 (40%), Gaps = 2/185 (1%)
Frame = +2
Query: 41 QEKEREEAGPDSILWSMSPISMQEDKLTLLKDC-LSAAEDYYRIDDYKGMYHSYFRLANF 217
QE E EE G + W M ++ K K+ L AA+ + ++ + +Y +
Sbjct: 505 QENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEE 564
Query: 218 FKSYPEDKWLVDHFFKYCWSVSKKINDDENLKHAEANYYLGLAIELNKDYEEAF-QYFHT 394
F+S C ++ ++ + + AE +Y LGLA N Y+EA Q+ +
Sbjct: 565 FQS--------------CLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKS 610
Query: 395 LYTLSKKQTWKNEHNVLLFIEACEHLSNIRLEMSESFLDNFKNIEMTQKISYLREALDYA 574
+ + + NE + E+ I E+ + + +RE ++ A
Sbjct: 611 IEVIENRMAVLNEQVKEAEGSSAEYKKEIE--------------ELKELLPEIREKIEDA 656
Query: 575 REGEK 589
+E ++
Sbjct: 657 KESQR 661
>sp|P27123|NASP_RABIT Nuclear autoantigenic sperm protein (NASP)
Length = 680
Score = 35.8 bits (81), Expect = 0.16
Identities = 31/132 (23%), Positives = 56/132 (42%), Gaps = 2/132 (1%)
Frame = +2
Query: 44 EKEREEAGPDSILWSMSPISMQEDKLTLLKDC-LSAAEDYYRIDDYKGMYHSYFRLANFF 220
E E EE G + W M ++ K K+ L AA+ + ++ + +Y + F
Sbjct: 399 ENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESQNYIQAVEEF 458
Query: 221 KSYPEDKWLVDHFFKYCWSVSKKINDDENLKHAEANYYLGLAIELNKDYEEAF-QYFHTL 397
++ C S+ ++ + + AE +Y LGLA N Y+EA Q+ ++
Sbjct: 459 QA--------------CLSLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSI 504
Query: 398 YTLSKKQTWKNE 433
+ K+ NE
Sbjct: 505 EVIEKRMAVLNE 516
>sp|P06180|HIBN_XENLA Histone-binding protein N1/N2
Length = 590
Score = 33.9 bits (76), Expect = 0.62
Identities = 26/117 (22%), Positives = 51/117 (43%), Gaps = 1/117 (0%)
Frame = +2
Query: 41 QEKEREEAGPDSILWSMSPISMQEDKLTLLKDC-LSAAEDYYRIDDYKGMYHSYFRLANF 217
+E E E+ G + W M + K K+ L AA+ + ++ + +Y +
Sbjct: 320 KETEEEDVGNLQLAWEMLDLCKTIFKRQQSKEAQLKAAQAHQKLGEVCIESENYSQAVED 379
Query: 218 FKSYPEDKWLVDHFFKYCWSVSKKINDDENLKHAEANYYLGLAIELNKDYEEAFQYF 388
F + C ++ K+ ++ + AE +Y+LGLA + + +EEA +F
Sbjct: 380 FLA--------------CLNIQKEHLEEHDRLLAETHYHLGLAYQYSSKHEEAISHF 422
>sp|Q6Q4D0|BRU1_ARATH BRUSHY protein 1 (TONSOKU protein) (MGOUN protein 3)
Length = 1311
Score = 33.9 bits (76), Expect = 0.62
Identities = 21/114 (18%), Positives = 50/114 (43%)
Frame = +2
Query: 542 ISYLREALDYAREGEKKKLQGKCSYKLGMAYQEADKPDVAINYLMQYYNISKSINDDENF 721
++ + A A E ++ Q + + +G + + A+ + Y+IS ++
Sbjct: 6 VAAAKRAYRKAEEVGDRREQARWANNVGDILKNHGEYVDALKWFRIDYDISVKYLPGKDL 65
Query: 722 CIACDALAKVFRSQKKYEECIKYLEEFAECAERSLQKEAHSQACRALGDVYNHL 883
C +L +++ + +EE + Y ++ + AE + +AC LG Y+ +
Sbjct: 66 LPTCQSLGEIYLRLENFEEALIYQKKHLQLAEEANDTVEKQRACTQLGRTYHEM 119
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,955,569
Number of Sequences: 369166
Number of extensions: 1589811
Number of successful extensions: 5630
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5359
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5620
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8838279920
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)