Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_A02
(888 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P42932|TCPQ_MOUSE T-complex protein 1, theta subunit (TC... 307 3e-83
sp|P50990|TCPQ_HUMAN T-complex protein 1, theta subunit (TC... 305 1e-82
sp|P78921|TCPQ_SCHPO Probable T-complex protein 1, theta su... 242 1e-63
sp|P47079|TCPQ_YEAST T-complex protein 1, theta subunit (TC... 238 1e-62
sp|P47828|TCPQ_CANAL T-complex protein 1, theta subunit (TC... 189 7e-48
sp|Q58405|THS_METJA Thermosome subunit (Chaperonin subunit) 158 2e-38
sp|O93624|THS_METTL Thermosome subunit (Chaperonin subunit) 145 2e-34
sp|P50016|THS_METKA Thermosome subunit (Chaperonin-like com... 144 3e-34
sp|O26885|THSB_METTH Thermosome beta subunit (Thermosome su... 144 4e-34
sp|O28045|THSA_ARCFU Thermosome alpha subunit (Thermosome s... 139 8e-33
>sp|P42932|TCPQ_MOUSE T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 548
Score = 307 bits (786), Expect = 3e-83
Identities = 152/284 (53%), Positives = 211/284 (74%)
Frame = +3
Query: 36 LIGMVFVREAQSVIKECKEAKVVVFSCPFDQLQTETKGTVLINTAKELMDFSRGEEDQME 215
L GMVF +E + + K+AK+ V+SCPFD + TETKGTVLI TA+ELM+FS+GEE+ M+
Sbjct: 218 LHGMVFKKETEGDVTSVKDAKIAVYSCPFDGMITETKGTVLIKTAEELMNFSKGEENLMD 277
Query: 216 ERVREIAETGCKVIVTGGKVGELALHYANKYNLMVVKLSSKFDIRRVCKVTGATPIPKLS 395
+V+ IA TG VIVTGGKV ++ALHYANKYN+M+V+L+SK+D+RR+CK GAT +PKL+
Sbjct: 278 AQVKAIAGTGANVIVTGGKVADIALHYANKYNIMLVRLNSKWDLRRLCKTVGATALPKLT 337
Query: 396 TPTQEELGYIASVRTEEIGKSTVVLFDQDVKEGAISSIVVRGSMYDMMDEVERAIDDGVN 575
P QEE+G+ SV E+G + VV+F + ++GAIS+IV+RGS ++MD++ERA+DDGVN
Sbjct: 338 PPVQEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVN 397
Query: 576 TFKCLTKEPRYLAGAGATEIELANRLSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAG 755
TFK LT++ R + G GATEIELA +++ + T GL QYAIK+F AFE+I + L +N+G
Sbjct: 398 TFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSG 457
Query: 756 ENATERIAELKAHHREGKTTFGIISTSEGRKVDDAVEHQILDTY 887
A E I++L + H+EG G+ +E V D +E ILDTY
Sbjct: 458 VKANEVISKLYSVHQEGNKNVGLDIEAEVPAVKDMLEASILDTY 501
>sp|P50990|TCPQ_HUMAN T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
sp|Q5RAP1|TCPQ_PONPY T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 548
Score = 305 bits (780), Expect = 1e-82
Identities = 150/284 (52%), Positives = 211/284 (74%)
Frame = +3
Query: 36 LIGMVFVREAQSVIKECKEAKVVVFSCPFDQLQTETKGTVLINTAKELMDFSRGEEDQME 215
L GMVF +E + + K+AK+ V+SCPFD + TETKGTVLI TA+ELM+FS+GEE+ M+
Sbjct: 218 LHGMVFKKETEGDVTSVKDAKIAVYSCPFDGMITETKGTVLIKTAEELMNFSKGEENLMD 277
Query: 216 ERVREIAETGCKVIVTGGKVGELALHYANKYNLMVVKLSSKFDIRRVCKVTGATPIPKLS 395
+V+ IA+TG V+VTGGKV ++ALHYANKYN+M+V+L+SK+D+RR+CK GAT +P+L+
Sbjct: 278 AQVKAIADTGANVVVTGGKVADMALHYANKYNIMLVRLNSKWDLRRLCKTVGATALPRLT 337
Query: 396 TPTQEELGYIASVRTEEIGKSTVVLFDQDVKEGAISSIVVRGSMYDMMDEVERAIDDGVN 575
P EE+G+ SV E+G + VV+F + ++GAIS+IV+RGS ++MD++ERA+DDGVN
Sbjct: 338 PPVLEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVN 397
Query: 576 TFKCLTKEPRYLAGAGATEIELANRLSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAG 755
TFK LT++ R + G GATEIELA +++ + T GL QYAIK+F AFE+I + L +N+G
Sbjct: 398 TFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSG 457
Query: 756 ENATERIAELKAHHREGKTTFGIISTSEGRKVDDAVEHQILDTY 887
A E I++L A H+EG G+ +E V D +E ILDTY
Sbjct: 458 VKANEVISKLYAVHQEGNKNVGLDIEAEVPAVKDMLEAGILDTY 501
>sp|P78921|TCPQ_SCHPO Probable T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 546
Score = 242 bits (617), Expect = 1e-63
Identities = 123/281 (43%), Positives = 183/281 (65%), Gaps = 1/281 (0%)
Frame = +3
Query: 42 GMVFVREAQSVIKECKEAKVVVFSCPFDQLQTETKGTVLINTAKELMDFSRGEEDQMEER 221
GMVF RE + + KEAKV VFSCP D QTETKGTVL++ A+E++DFS+GEE+ +E
Sbjct: 220 GMVFprePEGTVTRSKEAKVAVFSCPLDISQTETKGTVLLHNAQEMLDFSKGEENLIESH 279
Query: 222 VREIAETGCKVIVTGGKVGELALHYANKYNLMVVKLSSKFDIRRVCKVTGATPIPKLSTP 401
++EI + G +V+VT G V +L LHY N++ ++V+++ SKF++RR+C+V GATP+ ++ P
Sbjct: 280 IKEIYDAGVRVVVTSGNVNDLVLHYLNRFEILVIRVPSKFELRRLCRVVGATPLARMGVP 339
Query: 402 TQEELGYIASVRTEEIGKSTVVLFDQDVKEGAISSIVVRGSMYDMMDEVERAIDDGVNTF 581
EE+G + V T EIG V +F Q ++IV+RG+ +D++ERAIDDGVN
Sbjct: 340 MPEEMGSVDVVETIEIGGDRVTVFRQVEDITRTATIVLRGATKTYLDDLERAIDDGVNIV 399
Query: 582 KCLTKEPRYLAGAGATEIELANRLSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAGEN 761
K L K+ R + GAGA++++L RL G+ Q+AIKQ+ AFE + + + +NAG +
Sbjct: 400 KALVKDNRLIFGAGASDMQLCIRLISVGEKTPGIYQHAIKQYGEAFEVVPRTISENAGLD 459
Query: 762 ATERIAEL-KAHHREGKTTFGIISTSEGRKVDDAVEHQILD 881
T+ I++L AHH+E + G+ E DA E I D
Sbjct: 460 PTDVISKLYAAHHKENGESIGVDVECENDGTLDAKEAGIFD 500
>sp|P47079|TCPQ_YEAST T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 568
Score = 238 bits (608), Expect = 1e-62
Identities = 125/258 (48%), Positives = 177/258 (68%), Gaps = 6/258 (2%)
Frame = +3
Query: 42 GMVFVREAQSVIK---ECKEAKVVVFSCPFDQLQTETKGTVLINTAKELMDFSRGEEDQM 212
GMVF RE + +K E K+ KV VF+CP D TETKGTVL++ A+E++DFS+GEE Q+
Sbjct: 225 GMVFNREPEGHVKSLSEDKKHKVAVFTCPLDIANTETKGTVLLHNAQEMLDFSKGEEKQI 284
Query: 213 EERVREIAETGCKVIVTGGKVGELALHYANKYNLMVVKLSSKFDIRRVCKVTGATPIPKL 392
+ ++EIA+ G + IV G VGELALHY N+Y ++V+K+ SKF++RR+C+V GATP+P+L
Sbjct: 285 DAMMKEIADMGVECIVAGAGVGELALHYLNRYGILVLKVPSKFELRRLCRVCGATPLPRL 344
Query: 393 STPTQEELGYIASVRTEEIGKSTVVLFDQDVKE-GAISSIVVRGSMYDMMDEVERAIDDG 569
PT EELG + +V+T EIG V +F Q+ E S+I++RG+ + +D++ERAIDDG
Sbjct: 345 GAPTPEELGLVETVKTMEIGGDRVTVFKQEQGEISRTSTIILRGATQNNLDDIERAIDDG 404
Query: 570 VNTFKCLTKEP--RYLAGAGATEIELANRLSDFANTQTGLVQYAIKQFVLAFESIVKVLC 743
V K L K + L GAGATEIEL +R++ + GL+Q AIKQF +AFE + + L
Sbjct: 405 VAAVKGLMKPSGGKLLPGAGATEIELISRITKYGERTPGLLQLAIKQFAVAFEVVPRTLA 464
Query: 744 DNAGENATERIAELKAHH 797
+ AG + E + L A H
Sbjct: 465 ETAGLDVNEVLPNLYAAH 482
>sp|P47828|TCPQ_CANAL T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 540
Score = 189 bits (481), Expect = 7e-48
Identities = 106/275 (38%), Positives = 159/275 (57%), Gaps = 1/275 (0%)
Frame = +3
Query: 42 GMVFVREAQSVIKECKEAKVVVFSCPFDQLQTETKGTVLINTA-KELMDFSRGEEDQMEE 218
GMVF RE + +K + + P + +T ++ + R + +
Sbjct: 216 GMVFprePEGTVKNADQIQSCRVYQPHRYFHHRNQRYSCSSTMPRKCLISPRAKNNSWTS 275
Query: 219 RVREIAETGCKVIVTGGKVGELALHYANKYNLMVVKLSSKFDIRRVCKVTGATPIPKLST 398
R+ G + ++ G VGELALHY NKY ++V+++ SKFD+RR+C+V GATP+P+L
Sbjct: 276 CARKSTIQGLRWLLPGSSVGELALHYLNKYGILVLRVPSKFDLRRICQVCGATPLPRLGA 335
Query: 399 PTQEELGYIASVRTEEIGKSTVVLFDQDVKEGAISSIVVRGSMYDMMDEVERAIDDGVNT 578
PT +E+G I + T+EIG V +F QD ++IVVRG+ + +D++ERAIDDGVN+
Sbjct: 336 PTPDEMGEIDIIETKEIGGDRVTIFRQDESSSRTATIVVRGATQNNLDDIERAIDDGVNS 395
Query: 579 FKCLTKEPRYLAGAGATEIELANRLSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAGE 758
K L K+ R L GAGA EIEL R++ + +T GL+Q AIK F AFE I +VL + +G
Sbjct: 396 IKGLIKDNRLLPGAGAVEIELMKRITAYQST-PGLLQLAIKSFAKAFEVIPRVLAETSGH 454
Query: 759 NATERIAELKAHHREGKTTFGIISTSEGRKVDDAV 863
+++E +++L A H E I G D AV
Sbjct: 455 DSSEILSKLHAAHAEDTGLRAGIDIDSGEVADTAV 489
>sp|Q58405|THS_METJA Thermosome subunit (Chaperonin subunit)
Length = 542
Score = 158 bits (400), Expect = 2e-38
Identities = 93/278 (33%), Positives = 152/278 (54%), Gaps = 3/278 (1%)
Frame = +3
Query: 30 KYLIGMVFVREAQS--VIKECKEAKVVVFSCPFDQLQTETKGTVLINTAKELMDFSRGEE 203
K + G+V +E + + K+ + AK+ + +CP + +TET + I +LM+F EE
Sbjct: 211 KLIRGVVIDKERVNPQMPKKVENAKIALLNCPIEVKETETDAEIRITDPAKLMEFIEQEE 270
Query: 204 DQMEERVREIAETGCKVIVTGGKVGELALHYANKYNLMVVKLSSKFDIRRVCKVTGATPI 383
+++ V +IA TG V+ + +LA HY K ++ V+ K D+ ++ K TGA +
Sbjct: 271 KMIKDMVEKIAATGANVVFCQKGIDDLAQHYLAKKGILAVRRVKKSDMEKLAKATGARIV 330
Query: 384 PKLSTPTQEELGYIASVRTEEIGKSTVVLFDQDVKEGAISSIVVRGSMYDMMDEVERAID 563
K+ T E+LG V ++ ++ +Q A++ I+ RGS +++EV RAID
Sbjct: 331 TKIDDLTPEDLGEAGLVEERKVAGDAMIFVEQCKHPKAVT-ILARGSTEHVVEEVARAID 389
Query: 564 DGVNTFKCLTKEPRYLAGAGATEIELANRLSDFANTQTGLVQYAIKQFVLAFESIVKVLC 743
D + KC +E + +AG GATEIELA RL FA + G Q A+K F A E I + L
Sbjct: 390 DAIGVVKCALEEGKIVAGGGATEIELAKRLRKFAESVAGREQLAVKAFADALEVIPRTLA 449
Query: 744 DNAGENATERIAELK-AHHREGKTTFGIISTSEGRKVD 854
+N+G + + + +L+ AH +EG +G + EG VD
Sbjct: 450 ENSGLDPIDMLVKLRAAHEKEGGEVYG-LDVFEGEVVD 486
>sp|O93624|THS_METTL Thermosome subunit (Chaperonin subunit)
Length = 544
Score = 145 bits (365), Expect = 2e-34
Identities = 79/275 (28%), Positives = 147/275 (53%)
Frame = +3
Query: 57 REAQSVIKECKEAKVVVFSCPFDQLQTETKGTVLINTAKELMDFSRGEEDQMEERVREIA 236
R + + K+ + AK+ + +CP + +TET + I +LM+F EE +++ V I
Sbjct: 220 RVSPQMPKKIENAKIALLNCPIEVKETETDAEIRITDPTKLMEFIEQEEKMLKDMVDTIK 279
Query: 237 ETGCKVIVTGGKVGELALHYANKYNLMVVKLSSKFDIRRVCKVTGATPIPKLSTPTQEEL 416
+G V+ + +LA HY K ++ V+ K D+ ++ K TGA + + E+L
Sbjct: 280 ASGANVLFCQKGIDDLAQHYLAKEGILAVRRVKKSDMEKLSKATGANVVTNIKDLKAEDL 339
Query: 417 GYIASVRTEEIGKSTVVLFDQDVKEGAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTK 596
G V +I ++ F ++ K ++++RG+ +++EV RA+DD + C +
Sbjct: 340 GEAGIVEERKIAGDAMI-FVEECKHPKAVTMLIRGTTEHVIEEVARAVDDAIGVVACTIE 398
Query: 597 EPRYLAGAGATEIELANRLSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAGENATERI 776
+ + +AG GA EIELA +L D+A +G Q A++ F A E + + L +NAG +A E +
Sbjct: 399 DGKIVAGGGAAEIELAMKLRDYAEGVSGREQLAVRAFADALEVVPRTLAENAGLDAIEML 458
Query: 777 AELKAHHREGKTTFGIISTSEGRKVDDAVEHQILD 881
+L+A H EG + ++ G V++ E+ +++
Sbjct: 459 VKLRAKHAEGNNAYYGLNVFTG-DVENMTENGVVE 492
>sp|P50016|THS_METKA Thermosome subunit (Chaperonin-like complex) (CLIC)
Length = 545
Score = 144 bits (363), Expect = 3e-34
Identities = 79/263 (30%), Positives = 143/263 (54%), Gaps = 2/263 (0%)
Frame = +3
Query: 42 GMVFVREA--QSVIKECKEAKVVVFSCPFDQLQTETKGTVLINTAKELMDFSRGEEDQME 215
GMV +E + + + AK+ + +CP + +TET + I ++L F EE +
Sbjct: 220 GMVIDKERVHPGMPRRVENAKIALLNCPIEVKETETDAEIRITDPEQLQAFIEEEERMLS 279
Query: 216 ERVREIAETGCKVIVTGGKVGELALHYANKYNLMVVKLSSKFDIRRVCKVTGATPIPKLS 395
E V +IAETG V+ + +LA HY K ++ V+ K D++++ + TGA + +
Sbjct: 280 EMVDKIAETGANVVFCQKGIDDLAQHYLAKKGILAVRRVKKSDMQKLARATGARIVTNID 339
Query: 396 TPTQEELGYIASVRTEEIGKSTVVLFDQDVKEGAISSIVVRGSMYDMMDEVERAIDDGVN 575
++E+LG V +++ ++ F + K+ +I++RG ++DE ERAI+D +
Sbjct: 340 DLSEEDLGEAEVVEEKKVAGDKMI-FVEGCKDPKAVTILIRGGTEHVVDEAERAIEDAIG 398
Query: 576 TFKCLTKEPRYLAGAGATEIELANRLSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAG 755
++ + +AG GA E+E+A +L DFA+ G Q A++ F A E I + L +N+G
Sbjct: 399 VVAAALEDGKVVAGGGAPEVEVARQLRDFADGVEGREQLAVEAFADALEIIPRTLAENSG 458
Query: 756 ENATERIAELKAHHREGKTTFGI 824
+ + + +L+A H +G+ T GI
Sbjct: 459 LDPIDVLVQLRAKHEDGQVTAGI 481
>sp|O26885|THSB_METTH Thermosome beta subunit (Thermosome subunit 2) (Chaperonin beta
subunit)
Length = 538
Score = 144 bits (362), Expect = 4e-34
Identities = 80/259 (30%), Positives = 140/259 (54%)
Frame = +3
Query: 78 KECKEAKVVVFSCPFDQLQTETKGTVLINTAKELMDFSRGEEDQMEERVREIAETGCKVI 257
K+ + AK+ + +CP + +TE + I ++ F EE + + V I +TG V+
Sbjct: 225 KKVENAKIALLNCPIEVKETEVDAEIRITDPSQMQAFIEQEEQMIRDMVNSIVDTGANVL 284
Query: 258 VTGGKVGELALHYANKYNLMVVKLSSKFDIRRVCKVTGATPIPKLSTPTQEELGYIASVR 437
+ +LA HY K ++ V+ K D+ ++ K TGA + + + E+LG V
Sbjct: 285 FCQKGIDDLAQHYLAKAGVLAVRRVKKSDMEKLSKATGANIVTNIEDLSPEDLGEAGVVS 344
Query: 438 TEEIGKSTVVLFDQDVKEGAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAG 617
++I ++ F ++ KE +I+VRGS ++ EVERAI+D + ++ + +AG
Sbjct: 345 EKKISGEEMI-FVEECKEPKAVTILVRGSTEHVVSEVERAIEDAIGVVAATVEDGKVVAG 403
Query: 618 AGATEIELANRLSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHH 797
GA EIE+A RL D+A++ +G Q A+ F A E + K L +NAG ++ + + +L+A H
Sbjct: 404 GGAPEIEIAKRLKDYADSISGREQLAVSAFAEALEIVPKTLAENAGLDSIDVLVDLRAAH 463
Query: 798 REGKTTFGIISTSEGRKVD 854
E +T+ I +G+ VD
Sbjct: 464 EE--STYMGIDVFDGKIVD 480
>sp|O28045|THSA_ARCFU Thermosome alpha subunit (Thermosome subunit 1) (Chaperonin alpha
subunit)
Length = 545
Score = 139 bits (351), Expect = 8e-33
Identities = 84/267 (31%), Positives = 136/267 (50%), Gaps = 2/267 (0%)
Frame = +3
Query: 30 KYLIGMVFVREA--QSVIKECKEAKVVVFSCPFDQLQTETKGTVLINTAKELMDFSRGEE 203
K + G+V +E + K K AK+ V + +TET + I +LM F EE
Sbjct: 214 KLVNGIVIDKEVVHPGMPKRVKNAKIAVLKAALEVKETETDAEIRITDPDQLMKFIEQEE 273
Query: 204 DQMEERVREIAETGCKVIVTGGKVGELALHYANKYNLMVVKLSSKFDIRRVCKVTGATPI 383
++E V +AE G V+ + +LA +Y K ++ V+ + DI ++ K GA I
Sbjct: 274 KMLKEMVDRLAEAGANVVFCQKGIDDLAQYYLAKAGILAVRRVKQSDIEKIAKACGAKII 333
Query: 384 PKLSTPTQEELGYIASVRTEEIGKSTVVLFDQDVKEGAISSIVVRGSMYDMMDEVERAID 563
L T +LG V ++G +V F + K +I++RG ++DEVER++
Sbjct: 334 TDLREITSADLGEAELVEERKVGDEKMV-FIEGCKNPKAVTILIRGGSEHVVDEVERSLQ 392
Query: 564 DGVNTFKCLTKEPRYLAGAGATEIELANRLSDFANTQTGLVQYAIKQFVLAFESIVKVLC 743
D + K + + +AG GA EIE+A ++ D+A T G Q A + F A E I + L
Sbjct: 393 DAIKVVKTALESGKVVAGGGAPEIEVALKIRDWAPTLGGREQLAAEAFASALEVIPRALA 452
Query: 744 DNAGENATERIAELKAHHREGKTTFGI 824
+N+G + + + EL+ H EGKTT+G+
Sbjct: 453 ENSGLDPIDILVELRKAHEEGKTTYGV 479
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91,573,161
Number of Sequences: 369166
Number of extensions: 1713483
Number of successful extensions: 5549
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5227
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5472
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8886314050
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)