Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_004_N23
(866 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q6RUV5|RAC1_RAT Ras-related C3 botulinum toxin substrate... 327 2e-89
sp|P40792|RAC1_DROME Ras-related protein Rac1 325 1e-88
sp|Q9TU25|RAC2_BOVIN Ras-related C3 botulinum toxin substra... 323 4e-88
sp|P15153|RAC2_HUMAN Ras-related C3 botulinum toxin substra... 322 8e-88
sp|P60764|RAC3_MOUSE Ras-related C3 botulinum toxin substra... 321 1e-87
sp|Q05144|RAC2_MOUSE Ras-related C3 botulinum toxin substra... 320 2e-87
sp|P48554|RAC2_DROME Ras-related protein Rac2 319 7e-87
sp|O88931|RAC2_CAVPO Ras-related C3 botulinum toxin substra... 318 9e-87
sp|Q03206|RAC1_CAEEL RAS-related protein rac-1 (Cell-corpse... 308 2e-83
sp|O95916|RAC4_HUMAN Putative Ras-related C3 botulinum toxi... 301 2e-81
>sp|Q6RUV5|RAC1_RAT Ras-related C3 botulinum toxin substrate 1 (p21-Rac1)
sp|P63001|RAC1_MOUSE Ras-related C3 botulinum toxin substrate 1 (p21-Rac1)
sp|P63000|RAC1_HUMAN Ras-related C3 botulinum toxin substrate 1 (p21-Rac1) (Ras-like
protein TC25)
sp|P62999|RAC1_CANFA Ras-related C3 botulinum toxin substrate 1 (p21-Rac1) (Rac2)
sp|P62998|RAC1_BOVIN Ras-related C3 botulinum toxin substrate 1 (p21-Rac1)
Length = 192
Score = 327 bits (839), Expect = 2e-89
Identities = 156/190 (82%), Positives = 172/190 (90%)
Frame = +2
Query: 98 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAG 277
MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAG
Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60
Query: 278 QEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLR 457
QEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCPNTPIILVGTKLDLR
Sbjct: 61 QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR 120
Query: 458 ENLINGEAGRDRRNTPINYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPK 637
++ E ++++ TPI YPQGL +AKEIGAVKYLECSALTQ+GLK+VFDEAIRAVLCP
Sbjct: 121 DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP 180
Query: 638 PPRKKTCKFL 667
P +K+ K L
Sbjct: 181 PVKKRKRKCL 190
>sp|P40792|RAC1_DROME Ras-related protein Rac1
Length = 192
Score = 325 bits (833), Expect = 1e-88
Identities = 156/192 (81%), Positives = 171/192 (89%), Gaps = 2/192 (1%)
Frame = +2
Query: 98 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAG 277
MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KP+NLGLWDTAG
Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAG 60
Query: 278 QEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLR 457
QEDYDRLRPLSYPQTDVFLICFSL+N +S+ENVRAKWYPE+ HHCP+TPIILVGTKLDLR
Sbjct: 61 QEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHCPSTPIILVGTKLDLR 120
Query: 458 ENLINGEAGRDRRNTPINYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCP- 634
++ E RD++ PI YPQGL +AKEIGAVKYLECSALTQKGLK+VFDEAIR+VLCP
Sbjct: 121 DDKNTIEKLRDKKLAPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIRSVLCPV 180
Query: 635 -KPPRKKTCKFL 667
+P K+ C L
Sbjct: 181 LQPKSKRKCALL 192
>sp|Q9TU25|RAC2_BOVIN Ras-related C3 botulinum toxin substrate 2 (p21-Rac2)
Length = 192
Score = 323 bits (828), Expect = 4e-88
Identities = 154/192 (80%), Positives = 173/192 (90%), Gaps = 2/192 (1%)
Frame = +2
Query: 98 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAG 277
MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD+KPVNLGLWDTAG
Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG 60
Query: 278 QEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLR 457
QEDYDRLRPLSYPQTDVFLICFSL++ +SYENVRAKW+PE+ HHCP+TPIILVGTKLDLR
Sbjct: 61 QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLR 120
Query: 458 ENLINGEAGRDRRNTPINYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPK 637
++ E ++++ PI YPQGL LAKEI +VKYLECSALTQ+GLK+VFDEAIRAVLCP+
Sbjct: 121 DDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQ 180
Query: 638 P--PRKKTCKFL 667
P P+K+ C L
Sbjct: 181 PTRPQKRPCSIL 192
>sp|P15153|RAC2_HUMAN Ras-related C3 botulinum toxin substrate 2 (p21-Rac2) (Small G
protein) (GX)
Length = 192
Score = 322 bits (825), Expect = 8e-88
Identities = 154/192 (80%), Positives = 172/192 (89%), Gaps = 2/192 (1%)
Frame = +2
Query: 98 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAG 277
MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD+KPVNLGLWDTAG
Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG 60
Query: 278 QEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLR 457
QEDYDRLRPLSYPQTDVFLICFSL++ +SYENVRAKW+PE+ HHCP+TPIILVGTKLDLR
Sbjct: 61 QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLR 120
Query: 458 ENLINGEAGRDRRNTPINYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPK 637
++ E ++++ PI YPQGL LAKEI +VKYLECSALTQ+GLK+VFDEAIRAVLCP+
Sbjct: 121 DDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQ 180
Query: 638 PPR--KKTCKFL 667
P R K+ C L
Sbjct: 181 PTRQQKRACSLL 192
>sp|P60764|RAC3_MOUSE Ras-related C3 botulinum toxin substrate 3 (p21-Rac3)
sp|P60763|RAC3_HUMAN Ras-related C3 botulinum toxin substrate 3 (p21-Rac3)
Length = 192
Score = 321 bits (823), Expect = 1e-87
Identities = 151/184 (82%), Positives = 168/184 (91%)
Frame = +2
Query: 98 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAG 277
MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KPVNLGLWDTAG
Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60
Query: 278 QEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLR 457
QEDYDRLRPLSYPQTDVFLICFSL++ +S+ENVRAKWYPE+ HHCP+TPI+LVGTKLDLR
Sbjct: 61 QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLR 120
Query: 458 ENLINGEAGRDRRNTPINYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPK 637
++ E RD++ PI YPQGL +A+EIG+VKYLECSALTQ+GLK+VFDEAIRAVLCP
Sbjct: 121 DDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCPP 180
Query: 638 PPRK 649
P +K
Sbjct: 181 PVKK 184
>sp|Q05144|RAC2_MOUSE Ras-related C3 botulinum toxin substrate 2 (p21-Rac2) (EN-7
protein)
Length = 192
Score = 320 bits (821), Expect = 2e-87
Identities = 153/192 (79%), Positives = 172/192 (89%), Gaps = 2/192 (1%)
Frame = +2
Query: 98 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAG 277
MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD+KPVNLGLWDTAG
Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG 60
Query: 278 QEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLR 457
QEDYDRLRPLSYPQTDVFLICFSL++ +SYENVRAKW+PE+ HHCP+TPIILVGTKLDLR
Sbjct: 61 QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLR 120
Query: 458 ENLINGEAGRDRRNTPINYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPK 637
++ E ++++ PI YPQGL LAK+I +VKYLECSALTQ+GLK+VFDEAIRAVLCP+
Sbjct: 121 DDKDTIEKLKEKKLAPITYPQGLALAKDIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQ 180
Query: 638 PPR--KKTCKFL 667
P R K+ C L
Sbjct: 181 PTRQQKRPCSLL 192
>sp|P48554|RAC2_DROME Ras-related protein Rac2
Length = 192
Score = 319 bits (817), Expect = 7e-87
Identities = 152/192 (79%), Positives = 170/192 (88%), Gaps = 2/192 (1%)
Frame = +2
Query: 98 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAG 277
MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KP+NLGLWDTAG
Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAG 60
Query: 278 QEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLR 457
QEDYDRLRPLSYPQTDVFLICFSL+N +S+ENVRAKW+PE+ HHCP+ PIILVGTKLDLR
Sbjct: 61 QEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWFPEVRHHCPSVPIILVGTKLDLR 120
Query: 458 ENLINGEAGRDRRNTPINYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCP- 634
++ E +D++ TPI YPQGL +AKEI AVKYLECSALTQKGLK+VFDEAIR+VLCP
Sbjct: 121 DDKQTIEKLKDKKLTPITYPQGLAMAKEIAAVKYLECSALTQKGLKTVFDEAIRSVLCPV 180
Query: 635 -KPPRKKTCKFL 667
+ P++ C L
Sbjct: 181 VRGPKRHKCALL 192
>sp|O88931|RAC2_CAVPO Ras-related C3 botulinum toxin substrate 2 (p21-Rac2)
Length = 192
Score = 318 bits (816), Expect = 9e-87
Identities = 151/192 (78%), Positives = 171/192 (89%), Gaps = 2/192 (1%)
Frame = +2
Query: 98 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAG 277
MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD+KPVNLGLWDTAG
Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG 60
Query: 278 QEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLR 457
QEDYDRLRPLSYPQTDVFLICFSL++ +SYENV A WYP++ HHCP+TPIIL+GTKLDLR
Sbjct: 61 QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVHANWYPKVRHHCPSTPIILLGTKLDLR 120
Query: 458 ENLINGEAGRDRRNTPINYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPK 637
++ E ++++ PI YPQGL LAKEI +VKYLECSALTQ+GLK+VFDEAIRAVLCP+
Sbjct: 121 DDKETIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQ 180
Query: 638 P--PRKKTCKFL 667
P P+K+ C L
Sbjct: 181 PTRPQKRACSLL 192
>sp|Q03206|RAC1_CAEEL RAS-related protein rac-1 (Cell-corpse engulfment protein ced-10)
(CErac1)
Length = 191
Score = 308 bits (788), Expect = 2e-83
Identities = 148/186 (79%), Positives = 163/186 (87%)
Frame = +2
Query: 98 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAG 277
MQ IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD +P+NLGLWDTAG
Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPINLGLWDTAG 60
Query: 278 QEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLR 457
QEDYDRLRPLSYPQTDVFL+CF+L N +S+ENVRAKWYPE++HHCPNTPIILVGTK DLR
Sbjct: 61 QEDYDRLRPLSYPQTDVFLVCFALNNPASFENVRAKWYPEVSHHCPNTPIILVGTKADLR 120
Query: 458 ENLINGEAGRDRRNTPINYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPK 637
E+ E R+RR P++ QG V+AKEI AVKYLECSALTQ+GLK VFDEAIRAVL P
Sbjct: 121 EDRDTVERLRERRLQPVSQTQGYVMAKEIKAVKYLECSALTQRGLKQVFDEAIRAVLTPP 180
Query: 638 PPRKKT 655
KK+
Sbjct: 181 QRAKKS 186
>sp|O95916|RAC4_HUMAN Putative Ras-related C3 botulinum toxin substrate 4 (p21-Rac4)
Length = 192
Score = 301 bits (770), Expect = 2e-81
Identities = 145/190 (76%), Positives = 165/190 (86%)
Frame = +2
Query: 98 MQGIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAG 277
MQ IK VVVGDGAVGKTCLLISYTTNAFPGE IPT FDNYSANVMVD K VNLGLW+TAG
Sbjct: 1 MQAIKGVVVGDGAVGKTCLLISYTTNAFPGEDIPTAFDNYSANVMVDGKLVNLGLWNTAG 60
Query: 278 QEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLR 457
QEDYDRLRPLSYPQ DVFLICFSL++ +S+ENV AKWYPE+ HHCPNTPIILVGTKLDLR
Sbjct: 61 QEDYDRLRPLSYPQADVFLICFSLVSPASFENVLAKWYPEVQHHCPNTPIILVGTKLDLR 120
Query: 458 ENLINGEAGRDRRNTPINYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPK 637
++ + ++++ TPI YPQGL +AKE+GAVKYLEC ALT++GLK+VFDEAIRAVLCP
Sbjct: 121 DDKDRIQKLKEKKLTPITYPQGLAMAKEMGAVKYLECLALTRRGLKTVFDEAIRAVLCPP 180
Query: 638 PPRKKTCKFL 667
P +K+ K L
Sbjct: 181 PVKKRKRKCL 190
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 99,233,365
Number of Sequences: 369166
Number of extensions: 2172090
Number of successful extensions: 5774
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5200
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5314
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8550075140
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)