Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_004_N17
(703 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O95214|LERL1_HUMAN Leptin receptor overlapping transcrip... 137 2e-32
sp|O89013|OBRG_MOUSE Leptin receptor gene-related protein (... 137 4e-32
sp|O15243|OBRG_HUMAN Leptin receptor gene-related protein (... 137 4e-32
sp|Q9CQ74|LERL1_MOUSE Leptin receptor overlapping transcrip... 135 8e-32
sp|Q9JLS8|OBRG_RAT Leptin receptor gene-related protein (OB... 135 1e-31
sp|Q18319|YTO2_CAEEL Hypothetical protein C30B5.2 in chromo... 100 5e-21
sp|P47111|VPS55_YEAST Vacuolar protein sorting protein 55 61 3e-09
sp|P03893|NU2M_MOUSE NADH-ubiquinone oxidoreductase chain 2... 36 0.086
sp|P0AA93|YPDA_ECOLI Inner membrane protein ypdA 33 0.73
sp|Q96061|NU2M_RHIUN NADH-ubiquinone oxidoreductase chain 2... 32 2.1
>sp|O95214|LERL1_HUMAN Leptin receptor overlapping transcript-like 1
Length = 131
Score = 137 bits (346), Expect = 2e-32
Identities = 71/135 (52%), Positives = 96/135 (71%), Gaps = 2/135 (1%)
Frame = +3
Query: 36 MAQLKALIGLAFLASLGVTFLILACALEQYNKWWPLFVLLFHFLSPVPCLIAKKYSDSSE 215
MA +KALI L+F ++G+ FL+L CAL YNK+WPLFVL F+ LSP+P IA++ D ++
Sbjct: 1 MAGIKALISLSFGGAIGLMFLMLGCALPIYNKYWPLFVLFFYILSPIPYCIARRLVDDTD 60
Query: 216 --SSTLWDNCIFITSIIVVSGYGLPIVLAVAPLTGPIIKWGACFLVMASNTVIFSTILGF 389
S+ + IF+T+ IVVS +GLPIV A A L I+WGAC LV+ NTVIF+TILGF
Sbjct: 61 AMSNACKELAIFLTTGIVVSAFGLPIVFARAHL----IEWGACALVLTGNTVIFATILGF 116
Query: 390 FCLFGRENEFSYSGW 434
F +FG ++FS+ W
Sbjct: 117 FLVFGSNDDFSWQQW 131
>sp|O89013|OBRG_MOUSE Leptin receptor gene-related protein (OB-R gene related protein)
(OB-RGRP)
Length = 131
Score = 137 bits (344), Expect = 4e-32
Identities = 69/135 (51%), Positives = 93/135 (68%), Gaps = 2/135 (1%)
Frame = +3
Query: 36 MAQLKALIGLAFLASLGVTFLILACALEQYNKWWPLFVLLFHFLSPVPCLIAKK--YSDS 209
MA +KAL+ L+F ++G+TFL+L CALE Y +WPLFVL+F+ +SP+P IAK+ Y
Sbjct: 1 MAGVKALVALSFSGAIGLTFLMLGCALEDYGVYWPLFVLIFYVISPIPYFIAKRVTYDSD 60
Query: 210 SESSTLWDNCIFITSIIVVSGYGLPIVLAVAPLTGPIIKWGACFLVMASNTVIFSTILGF 389
+ SS + F T+ IVVS +GLP+VLA +IKWGAC LV+A N VIF TI GF
Sbjct: 61 ATSSACRELAYFFTTGIVVSAFGLPVVLARV----DVIKWGACGLVLAGNAVIFLTIQGF 116
Query: 390 FCLFGRENEFSYSGW 434
F +FGR ++FS+ W
Sbjct: 117 FLVFGRGDDFSWEQW 131
>sp|O15243|OBRG_HUMAN Leptin receptor gene-related protein (OB-R gene related protein)
(OB-RGRP) (Leptin receptor overlapping transcript
protein)
Length = 131
Score = 137 bits (344), Expect = 4e-32
Identities = 68/135 (50%), Positives = 92/135 (68%), Gaps = 2/135 (1%)
Frame = +3
Query: 36 MAQLKALIGLAFLASLGVTFLILACALEQYNKWWPLFVLLFHFLSPVPCLIAKK--YSDS 209
MA +KAL+ L+F ++G+TFL+L CALE Y +WPLFVL+FH +SP+P IAK+ Y
Sbjct: 1 MAGVKALVALSFSGAIGLTFLMLGCALEDYGVYWPLFVLIFHAISPIPHFIAKRVTYDSD 60
Query: 210 SESSTLWDNCIFITSIIVVSGYGLPIVLAVAPLTGPIIKWGACFLVMASNTVIFSTILGF 389
+ SS + F T+ IVVS +G P++LA +IKWGAC LV+A N VIF TI GF
Sbjct: 61 ATSSACRELAYFFTTGIVVSAFGFPVILARV----AVIKWGACGLVLAGNAVIFLTIQGF 116
Query: 390 FCLFGRENEFSYSGW 434
F +FGR ++FS+ W
Sbjct: 117 FLIFGRGDDFSWEQW 131
>sp|Q9CQ74|LERL1_MOUSE Leptin receptor overlapping transcript-like 1
Length = 131
Score = 135 bits (341), Expect = 8e-32
Identities = 69/135 (51%), Positives = 96/135 (71%), Gaps = 2/135 (1%)
Frame = +3
Query: 36 MAQLKALIGLAFLASLGVTFLILACALEQYNKWWPLFVLLFHFLSPVPCLIAKKYSDSSE 215
MA +KALI L+F ++G+ FL+L CAL YN++WPLFVL F+ LSP+P IA++ D ++
Sbjct: 1 MAGIKALISLSFGGAIGLMFLMLGCALPIYNQYWPLFVLFFYILSPIPYCIARRLVDDTD 60
Query: 216 --SSTLWDNCIFITSIIVVSGYGLPIVLAVAPLTGPIIKWGACFLVMASNTVIFSTILGF 389
S+ + IF+T+ IVVS +GLP+V A A L I+WGAC LV+ NTVIF+TILGF
Sbjct: 61 AMSNACKELAIFLTTGIVVSAFGLPVVFARAHL----IEWGACALVLTGNTVIFATILGF 116
Query: 390 FCLFGRENEFSYSGW 434
F +FG ++FS+ W
Sbjct: 117 FLVFGSNDDFSWQQW 131
>sp|Q9JLS8|OBRG_RAT Leptin receptor gene-related protein (OB-R gene related protein)
(OB-RGRP)
Length = 131
Score = 135 bits (339), Expect = 1e-31
Identities = 67/135 (49%), Positives = 92/135 (68%), Gaps = 2/135 (1%)
Frame = +3
Query: 36 MAQLKALIGLAFLASLGVTFLILACALEQYNKWWPLFVLLFHFLSPVPCLIAKK--YSDS 209
MA +KAL+ L+F ++G+TFL+L CALE Y +WPLFVL+F+ +SP+P IAK+ Y
Sbjct: 1 MAGVKALVALSFSGAIGLTFLMLGCALEDYGVYWPLFVLIFYVISPIPYFIAKRVTYDSD 60
Query: 210 SESSTLWDNCIFITSIIVVSGYGLPIVLAVAPLTGPIIKWGACFLVMASNTVIFSTILGF 389
+ SS + F T+ IVVS +G P++LA +IKWGAC LV+A N VIF TI GF
Sbjct: 61 ATSSACRELAYFFTTGIVVSAFGFPVILARV----AVIKWGACGLVLAGNAVIFLTIQGF 116
Query: 390 FCLFGRENEFSYSGW 434
F +FGR ++FS+ W
Sbjct: 117 FLVFGRGDDFSWEQW 131
>sp|Q18319|YTO2_CAEEL Hypothetical protein C30B5.2 in chromosome II
Length = 132
Score = 100 bits (248), Expect = 5e-21
Identities = 55/132 (41%), Positives = 84/132 (63%), Gaps = 1/132 (0%)
Frame = +3
Query: 36 MAQLKALIGLAFLASLGVTFLILACALEQYNKWWPLFVLLFHFLSPVPCLIAKKY-SDSS 212
M ++A+ LAF +G+TFL+L CAL +Y W P+FV+ F+ LSPVP LIA+++ D +
Sbjct: 1 MGGVRAVAALAFAGVVGLTFLVLGCALPRYGTWTPMFVITFYVLSPVPLLIARRFQEDMT 60
Query: 213 ESSTLWDNCIFITSIIVVSGYGLPIVLAVAPLTGPIIKWGACFLVMASNTVIFSTILGFF 392
++ + +FIT+ IV+S + LPIVLA A G I ACFLV + ++F TI+ +F
Sbjct: 61 GTNACIELALFITTGIVISAFALPIVLAHA---GTIAN-SACFLVNTGSVIMFGTIIAYF 116
Query: 393 CLFGRENEFSYS 428
L ++ S+S
Sbjct: 117 YLHRDDDSGSWS 128
>sp|P47111|VPS55_YEAST Vacuolar protein sorting protein 55
Length = 140
Score = 61.2 bits (147), Expect = 3e-09
Identities = 45/137 (32%), Positives = 74/137 (54%), Gaps = 8/137 (5%)
Frame = +3
Query: 24 LFEF-MAQLKALIGLAFLASLGVTFLILACALEQYNKWWPLFVLLFHFLSPVPCLI---A 191
+ EF ++ L +I L+ +LG +IL+CAL ++ ++PLF +L L+P+P I
Sbjct: 1 MMEFKVSPLTKIISLSGFLALGFLLVILSCAL--FHNYYPLFDILIFLLAPIPNTIFNAG 58
Query: 192 KKY--SD--SSESSTLWDNCIFITSIIVVSGYGLPIVLAVAPLTGPIIKWGACFLVMASN 359
KY SD S S+T D F+T ++V SG LP+V L G + +C + M
Sbjct: 59 NKYHTSDFMSDSSNTGQDLAHFLTGMLVTSGIALPVVFYHCQLIGHL----SCIMCMIGG 114
Query: 360 TVIFSTILGFFCLFGRE 410
+I+S+I+ F F ++
Sbjct: 115 LIIYSSIVIFKWFFKKD 131
>sp|P03893|NU2M_MOUSE NADH-ubiquinone oxidoreductase chain 2 (NADH dehydrogenase subunit
2)
Length = 345
Score = 36.2 bits (82), Expect = 0.086
Identities = 31/125 (24%), Positives = 59/125 (47%), Gaps = 6/125 (4%)
Frame = +3
Query: 42 QLKALIGLAFLASLGVTFLILACALEQYNKWWPLFVLLFHFLSPVPCLIAKKYSDS---S 212
Q++ ++ + +A +G IL YN L L+ + + P +A ++S +
Sbjct: 174 QMRKIMAYSSIAHMGWMLAILP-----YNPSLTLLNLMIYIILTAPMFMALMLNNSMTIN 228
Query: 213 ESSTLWDNC---IFITSIIVVSGYGLPIVLAVAPLTGPIIKWGACFLVMASNTVIFSTIL 383
S LW+ + + S++++S GLP PLTG + KW +M +N +I +T++
Sbjct: 229 SISLLWNKTPAMLTMISLMLLSLGGLP------PLTGFLPKWIIITELMKNNCLIMATLM 282
Query: 384 GFFCL 398
L
Sbjct: 283 AMMAL 287
>sp|P0AA93|YPDA_ECOLI Inner membrane protein ypdA
Length = 565
Score = 33.1 bits (74), Expect = 0.73
Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 2/63 (3%)
Frame = -1
Query: 382 RIVENITVLLAITKKQAPHFMIGPVNGATAKTIGRP*PDTTIMLVINIQ--LSHNVELSD 209
R + N L A+ K PHF+ +N ++ R PDT L+ N+ L +N+EL D
Sbjct: 353 REMANKAELRALQSKINPHFLFNALNAISSSI--RLNPDTARQLIFNLSRYLRYNIELKD 410
Query: 208 ESE 200
+ +
Sbjct: 411 DEQ 413
>sp|Q96061|NU2M_RHIUN NADH-ubiquinone oxidoreductase chain 2 (NADH dehydrogenase subunit
2)
Length = 347
Score = 31.6 bits (70), Expect = 2.1
Identities = 30/125 (24%), Positives = 56/125 (44%), Gaps = 6/125 (4%)
Frame = +3
Query: 42 QLKALIGLAFLASLGVTFLILACALEQYNKWWPLFVLLFHFLSPVPCLIAKKYSDSSESS 221
QL+ ++ + +A +G IL YN + +L + + + + + S+ +
Sbjct: 174 QLRKIMAYSSIAHMGWMTAILT-----YNPTMTMLNMLIYIMMTLTTFMLLMLNSSTTTL 228
Query: 222 TL---WDNCIFITSIIVV---SGYGLPIVLAVAPLTGPIIKWGACFLVMASNTVIFSTIL 383
+L W+ ITS+I++ S GLP PL+G I KW + +N++I T +
Sbjct: 229 SLSHTWNKTPLITSLILIIMLSLGGLP------PLSGFIPKWMIIQELTKNNSIILPTSM 282
Query: 384 GFFCL 398
L
Sbjct: 283 AIMAL 287
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,682,658
Number of Sequences: 369166
Number of extensions: 1537972
Number of successful extensions: 3585
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3494
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3572
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6122130210
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)