Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_004_M22
(628 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8NDV7|TNR6A_HUMAN Trinucleotide repeat-containing gene ... 43 8e-04
sp|Q9JL19|NCOA6_MOUSE Nuclear receptor coactivator 6 (Ampli... 34 0.27
sp|Q14686|NCOA6_HUMAN Nuclear receptor coactivator 6 (Ampli... 33 0.46
sp|Q03466|EBS1_YEAST Protein EBS1 (EST1-like BCY1 suppresso... 33 0.60
sp|P13468|K10_DROME DNA-binding protein K10 (Female sterile... 33 0.60
sp|P05453|ERF2_YEAST Eukaryotic peptide chain release facto... 33 0.78
sp|P40356|MED3_YEAST RNA polymerase II mediator complex sub... 33 0.78
sp|Q60865|GP137_MOUSE GPI-anchored protein p137 (p137GPI) 33 0.78
sp|Q95XZ5|NPBL_CAEEL Nipped-B-like protein pqn-85 (Prion-li... 32 1.0
sp|P14196|AAC2_DICDI AAC-rich mRNA clone AAC11 protein 32 1.0
>sp|Q8NDV7|TNR6A_HUMAN Trinucleotide repeat-containing gene 6A protein (CAG repeat protein
26) (Glycin-tryptophan protein of 182 kDa) (GW182
autoantigen) (GW1 protein) (EMSY interactor protein)
Length = 1962
Score = 42.7 bits (99), Expect = 8e-04
Identities = 38/143 (26%), Positives = 60/143 (41%), Gaps = 13/143 (9%)
Frame = +2
Query: 113 PGTRSQSNNLTSVNWGNSSDKSMFNANQIKPSGVNWNAPVNITASPQLQMQQPVGTGNSG 292
P ++S+S+N WG S S N + + + + + L ++ PVG+G+SG
Sbjct: 331 PESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSG 390
Query: 293 YGIQMTSCMQYMPANYNQSYQ---NQMHPQFG---------VGYNNNMNF-GQPLNPQNP 433
IQ ++ Q MP N + + + H +G V ++F GQP N
Sbjct: 391 INIQCSTIGQ-MPNNQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTE 449
Query: 434 FLSQNNTQNFMPFQSQNQSTYPN 502
NNT NFM N + N
Sbjct: 450 MTGPNNTTNFMTSSLPNSGSVQN 472
>sp|Q9JL19|NCOA6_MOUSE Nuclear receptor coactivator 6 (Amplified in breast cancer-3
protein) (Cancer-amplified transcriptional coactivator
ASC-2) (Activating signal cointegrator-2) (ASC-2)
(Peroxisome proliferator-activated receptor-interacting
protein) (PPAR-interacting protein) (Nuclear
receptor-activating protein, 250 kDa) (Nuclear receptor
coactivator RAP250) (NRC) (Thyroid hormone receptor
binding protein)
Length = 2067
Score = 34.3 bits (77), Expect = 0.27
Identities = 41/141 (29%), Positives = 59/141 (41%), Gaps = 6/141 (4%)
Frame = +2
Query: 125 SQSNNLTSVNWGNSSDKSMFNANQIKPSGVNWNAPVNITASPQLQMQQPVGTGNSGYGIQ 304
SQ + N+ S+ F A Q+K G+ P + +QQP T N
Sbjct: 384 SQQASQAHTNFPQMSNPGQFTAPQMK--GLQ-GGPSRVPTP----LQQPHLT-NKSPASS 435
Query: 305 MTSCMQYMPAN---YNQSYQNQMHPQFGVGYNNNMNFGQPLNP--QNPFLSQNNTQ-NFM 466
+S Q PA+ NQ+ Q QM P+ + F QP++ +NP + Q N NFM
Sbjct: 436 PSSFQQGSPASSPTVNQT-QQQMGPRPPQNNPLSQGFQQPVSSPGRNPMVQQGNVPPNFM 494
Query: 467 PFQSQNQSTYPNQLHSQFGSL 529
Q Q + P LH G +
Sbjct: 495 VMQQQPPNQGPQSLHPGLGGM 515
>sp|Q14686|NCOA6_HUMAN Nuclear receptor coactivator 6 (Amplified in breast cancer-3
protein) (Cancer-amplified transcriptional coactivator
ASC-2) (Activating signal cointegrator-2) (ASC-2)
(Peroxisome proliferator-activated receptor-interacting
protein) (PPAR-interacting protein) (PRIP) (Nuclear
receptor-activating protein, 250 kDa) (Nuclear receptor
coactivator RAP250) (NRC RAP250) (Thyroid hormone
receptor-binding protein)
Length = 2063
Score = 33.5 bits (75), Expect = 0.46
Identities = 36/140 (25%), Positives = 51/140 (36%), Gaps = 5/140 (3%)
Frame = +2
Query: 125 SQSNNLTSVNWGNSSDKSMFNANQIKPSGVNWNAPVNITASPQLQMQQPVGTGNSGYGIQ 304
SQ + N+ S+ F A Q+K + P L + P + +S Q
Sbjct: 380 SQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSS---FQ 436
Query: 305 MTSCMQYMPANYNQSYQNQMHPQFGVGYNNNM--NFGQPLNP--QNPFLSQNNTQ-NFMP 469
S N Q PQ NN + F QP++ +NP + Q N NFM
Sbjct: 437 QGSPASSPTVNQTQQQMGPRPPQ-----NNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMV 491
Query: 470 FQSQNQSTYPNQLHSQFGSL 529
Q Q + P LH G +
Sbjct: 492 MQQQPPNQGPQSLHPGLGGM 511
>sp|Q03466|EBS1_YEAST Protein EBS1 (EST1-like BCY1 suppressor 1)
Length = 884
Score = 33.1 bits (74), Expect = 0.60
Identities = 38/142 (26%), Positives = 55/142 (38%), Gaps = 15/142 (10%)
Frame = +2
Query: 104 NIGPGTRSQSNNLTSVNWGNSSDKSMFNANQIKPS---------------GVNWNAPVNI 238
NI PG + +++ NS+D+S F+ N I S GVN P N
Sbjct: 691 NISPGYSN-----AAISSSNSTDESSFDLNNILSSMQQKHAEKSFAKSMQGVNEQIPAND 745
Query: 239 TASPQLQMQQPVGTGNSGYGIQMTSCMQYMPANYNQSYQNQMHPQFGVGYNNNMNFGQPL 418
Q Q+P+ G Y Q S M ++ N +YQN P +
Sbjct: 746 VCH---QAQRPMQGGL--YSSQQPSSM----SSLNSAYQNASMPPSA----------SMV 786
Query: 419 NPQNPFLSQNNTQNFMPFQSQN 484
+ PFL+Q F P+ +QN
Sbjct: 787 SYPYPFLNQQGQGVFPPYNAQN 808
>sp|P13468|K10_DROME DNA-binding protein K10 (Female sterile protein K10)
Length = 463
Score = 33.1 bits (74), Expect = 0.60
Identities = 40/170 (23%), Positives = 64/170 (37%), Gaps = 25/170 (14%)
Frame = +2
Query: 86 YLAGNLNIGPGTRSQSNNLTSVNWGNSSDKSMFNANQIK--PSGVNWNAPV-----NITA 244
+ +G +N GPG N + N +++ MF+++Q+ P +++++P N
Sbjct: 62 FRSGKINSGPGGNGNGNRV------NGNNQMMFSSSQMPSDPLYIDFSSPPPGFKHNQVG 115
Query: 245 SPQLQ--------------MQQPVGTGNSGYGI----QMTSCMQYMPANYNQSYQNQMHP 370
SP+ + QQP + Q S Q N NQ Q + P
Sbjct: 116 SPKKKSMKGIKQQQHPSPNQQQPPSPNQQQHPSPNQQQHPSPNQQQHPNSNQ--QQHLSP 173
Query: 371 QFGVGYNNNMNFGQPLNPQNPFLSQNNTQNFMPFQSQNQSTYPNQLHSQF 520
G NN N Q PF +Q N ++ N PNQ+ F
Sbjct: 174 NQQQGKMNNQNNNHMNQSQQPFNNQMNGSDWQRHPGNN----PNQIRGGF 219
>sp|P05453|ERF2_YEAST Eukaryotic peptide chain release factor GTP-binding subunit (ERF2)
(Translation release factor 3) (ERF3) (ERF-3)
(Omnipotent suppressor protein 2) (G1 to S phase
transition protein 1)
Length = 685
Score = 32.7 bits (73), Expect = 0.78
Identities = 22/73 (30%), Positives = 29/73 (39%), Gaps = 1/73 (1%)
Frame = +2
Query: 284 NSGYGIQMTSCMQYMPANYNQSYQNQMHPQFGVGYNNNMNFGQPLNP-QNPFLSQNNTQN 460
++GY Q Y N YQ Q +PQ G G N N+ L Q F Q+ +
Sbjct: 66 DAGYQQQYNPQGGYQQYNPQGGYQQQFNPQGGRGNYKNFNYNNNLQGYQAGFQPQSQGMS 125
Query: 461 FMPFQSQNQSTYP 499
FQ Q + P
Sbjct: 126 LNDFQKQQKQAAP 138
>sp|P40356|MED3_YEAST RNA polymerase II mediator complex subunit 3 (Poly-glutamine domain
protein 1) (Hyper-recombination suppressor protein 1)
Length = 397
Score = 32.7 bits (73), Expect = 0.78
Identities = 27/96 (28%), Positives = 33/96 (34%)
Frame = +2
Query: 203 PSGVNWNAPVNITASPQLQMQQPVGTGNSGYGIQMTSCMQYMPANYNQSYQNQMHPQFGV 382
PS +N +P N+ +P M P+G Y NQ Q M G
Sbjct: 260 PSMINSVSPTNVMGTPLTNMMSPMGNA-------------YSMGAQNQGGQVSMSQFNGS 306
Query: 383 GYNNNMNFGQPLNPQNPFLSQNNTQNFMPFQSQNQS 490
G +N N N P SQ N N P N S
Sbjct: 307 GNGSNPNTNTNSN-NTPLQSQLNLNNLTPANILNMS 341
>sp|Q60865|GP137_MOUSE GPI-anchored protein p137 (p137GPI)
Length = 656
Score = 32.7 bits (73), Expect = 0.78
Identities = 31/120 (25%), Positives = 50/120 (41%), Gaps = 4/120 (3%)
Frame = +2
Query: 20 YQPQ-VNSKAPEIQPMALDDKLAYLAGNLNIGPGTRSQSNNLTSVNWGNSSDKSMFNANQ 196
YQP + P+ +PM + +++ + S++L + +S +F A
Sbjct: 396 YQPSHATEQRPQKEPMD------QIQATISLNTDQTTASSSLPA-----ASQPQVFQAGT 444
Query: 197 IKP---SGVNWNAPVNITASPQLQMQQPVGTGNSGYGIQMTSCMQYMPANYNQSYQNQMH 367
KP SG+N NA + M PV N ++ S Q A YNQS+ +Q H
Sbjct: 445 SKPLHSSGINVNAAPFQSMQTVFNMNAPVPPANEPETLKQQSQYQ---ATYNQSFSSQPH 501
>sp|Q95XZ5|NPBL_CAEEL Nipped-B-like protein pqn-85 (Prion-like-(Q/n-rich)-domain-bearing
protein 85) (SCC2 homolog)
Length = 2203
Score = 32.3 bits (72), Expect = 1.0
Identities = 30/101 (29%), Positives = 38/101 (37%), Gaps = 10/101 (9%)
Frame = +2
Query: 215 NWNAPVNITASPQLQMQQPVGTGNSGYGIQM---------TSCMQYMPANYNQSYQNQMH 367
N +N T +P Q PV T G+G QM + QY P Q Y N
Sbjct: 5 NLQNSLNGTGNPNFQ---PVQTNAGGFGHQMAQTGAAAAAAATGQYNPMLLQQQYLNF-- 59
Query: 368 PQFGVGYNNNM-NFGQPLNPQNPFLSQNNTQNFMPFQSQNQ 487
FG+ YNN + +F Q +L Q Q Q Q
Sbjct: 60 -GFGMNYNNQLFDFQAQQQQQQQYLMQQQQQQQQLHHQQQQ 99
>sp|P14196|AAC2_DICDI AAC-rich mRNA clone AAC11 protein
Length = 448
Score = 32.3 bits (72), Expect = 1.0
Identities = 29/127 (22%), Positives = 47/127 (37%), Gaps = 3/127 (2%)
Frame = +2
Query: 98 NLNIGPGTRSQSNNLTSVNWGNSSDKSMFNANQIKPSGVNWNAPVNITASPQLQMQQPVG 277
N N T + +NN+ + N N+++ + NAN + N N +P Q
Sbjct: 318 NNNTNNNTNNNNNNINNNN--NNTNNNNNNANNQNTNNNNMGNNSNNNNNPNNNNHQNNN 375
Query: 278 TGNSGYGIQMTSCMQYMPANYNQSYQNQMHPQFG-VGYNNNMNFGQPLNP--QNPFLSQN 448
N+ T+ P N + G +G + ++ P NP Q F
Sbjct: 376 NNNTSNNSNTTTATTTAPGGNNLTNSLNNAGNLGNLGRVSGLHSSDPNNPNAQKSFPDST 435
Query: 449 NTQNFMP 469
NT +F P
Sbjct: 436 NTMDFQP 442
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,760,947
Number of Sequences: 369166
Number of extensions: 1503901
Number of successful extensions: 3940
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3695
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3910
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 4974853140
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)