Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_004_M20
(851 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O14807|RASM_HUMAN Ras-related protein M-Ras (Ras-related... 178 2e-44
sp|P97538|RASM_RAT Ras-related protein M-Ras (Ras-related p... 177 3e-44
sp|O08989|RASM_MOUSE Ras-related protein M-Ras (Ras-related... 176 7e-44
sp|P38976|RAS2_HYDMA Ras-like protein RAS2 160 3e-39
sp|O74650|RAS_CRYNE Ras-like protein 159 1e-38
sp|P04388|RAS2_DROME Ras-like protein 2 158 2e-38
sp|P08647|RAS_SCHPO Ras-like protein 1 156 6e-38
sp|P62070|RRAS2_HUMAN Ras-related protein R-Ras2 (Ras-like ... 156 8e-38
sp|Q05058|RASL_COPCI 24 kDa RAS-like protein 156 8e-38
sp|P22278|RAS1_RHIRA Ras-like protein 1 155 1e-37
>sp|O14807|RASM_HUMAN Ras-related protein M-Ras (Ras-related protein R-Ras3)
Length = 208
Score = 178 bits (451), Expect = 2e-44
Identities = 93/190 (48%), Positives = 129/190 (67%)
Frame = +3
Query: 42 LPSDLSNMAKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNL 221
+PSD N+ K KSA+ +QF QKIFV ++DPTIE +Y K+ E+D +W+ L
Sbjct: 6 VPSD--NLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAIL 63
Query: 222 EVQDTAGQEEFAAMRESYYRTANGFLIVFSLTTRESFDMVRRFHKSALRSRDRDHFPMLL 401
+V DTAGQEEF+AMRE Y RT +GFLIV+S+T + SF+ V RFH+ LR +DR+ FPM+L
Sbjct: 64 DVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMIL 123
Query: 402 VANKTDLESSRKVSPSEIEDLAKELQIDYTETSAKNPPVNIDDAFSQIVRKIRSHQLIND 581
VANK DL RK++ + +++A + I Y ETSAK+PP+N+D AF +VR IR Q I +
Sbjct: 124 VANKVDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIR--QQIPE 181
Query: 582 VKTKSRPRQK 611
K + + K
Sbjct: 182 KSQKKKKKTK 191
>sp|P97538|RASM_RAT Ras-related protein M-Ras (Ras-related protein R-Ras3)
Length = 208
Score = 177 bits (450), Expect = 3e-44
Identities = 91/188 (48%), Positives = 126/188 (67%)
Frame = +3
Query: 42 LPSDLSNMAKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNL 221
+PSD N+ K KSA+ +QF QKIFV ++DPTIE +Y K+ E+D +W+ L
Sbjct: 6 VPSD--NLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAIL 63
Query: 222 EVQDTAGQEEFAAMRESYYRTANGFLIVFSLTTRESFDMVRRFHKSALRSRDRDHFPMLL 401
+V DTAGQEEF+AMRE Y RT +GFLIV+S+T + SF+ V RFH+ LR +DR+ FPM+L
Sbjct: 64 DVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMIL 123
Query: 402 VANKTDLESSRKVSPSEIEDLAKELQIDYTETSAKNPPVNIDDAFSQIVRKIRSHQLIND 581
VANK DL RKV+ + +++A + I Y ETSAK+PP+N+D F +VR IR +
Sbjct: 124 VANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDLVRVIRQQVPEKN 183
Query: 582 VKTKSRPR 605
K K + +
Sbjct: 184 QKKKKKTK 191
>sp|O08989|RASM_MOUSE Ras-related protein M-Ras (Ras-related protein R-Ras3) (Muscle and
microspikes Ras) (X-Ras)
Length = 208
Score = 176 bits (446), Expect = 7e-44
Identities = 90/188 (47%), Positives = 126/188 (67%)
Frame = +3
Query: 42 LPSDLSNMAKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNL 221
+PS+ N+ K KSA+ +QF QKIFV ++DPTIE +Y K+ E+D +W+ L
Sbjct: 6 VPSE--NLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAIL 63
Query: 222 EVQDTAGQEEFAAMRESYYRTANGFLIVFSLTTRESFDMVRRFHKSALRSRDRDHFPMLL 401
+V DTAGQEEF+AMRE Y RT +GFLIV+S+T + SF+ V RFH+ LR +DR+ FPM+L
Sbjct: 64 DVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMIL 123
Query: 402 VANKTDLESSRKVSPSEIEDLAKELQIDYTETSAKNPPVNIDDAFSQIVRKIRSHQLIND 581
VANK DL RKV+ + +++A + I Y ETSAK+PP+N+D F +VR IR +
Sbjct: 124 VANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDLVRVIRQQVPEKN 183
Query: 582 VKTKSRPR 605
K K + +
Sbjct: 184 QKKKKKTK 191
>sp|P38976|RAS2_HYDMA Ras-like protein RAS2
Length = 192
Score = 160 bits (406), Expect = 3e-39
Identities = 81/175 (46%), Positives = 122/175 (69%), Gaps = 1/175 (0%)
Frame = +3
Query: 108 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFAAMRESYYRTA 287
KSA+ +QF+Q FV+++DPTIE +Y K +D + ++L++ DTAGQEEF+AMR+ Y RT
Sbjct: 21 KSALTIQFIQSHFVQDYDPTIEDSYRKQCVIDDKVAHLDILDTAGQEEFSAMRDEYMRTG 80
Query: 288 NGFLIVFSLTTRESFDMVRRFHKSALRSRDRDHFPMLLVANKTDLESSRKVSPSEIEDLA 467
GFL+VFS+T R SFD + RFH LR +D + FPM+LV NK+DLE+ R VS +E ++L
Sbjct: 81 EGFLLVFSVTDRSSFDEIPRFHTQILRVKDIEEFPMILVGNKSDLENERTVSTAEAQELG 140
Query: 468 KELQIDYTETSAKNPPVNIDDAFSQIVRKIRSHQLINDVKTKS-RPRQKQKCCLM 629
++L++ Y E+SAK +N+D AF +VR IR+ N + R ++K + C++
Sbjct: 141 RKLKVSYLESSAKQ-RINVDAAFHDLVRAIRN---ANKASVEPLRKKEKSRRCIV 191
>sp|O74650|RAS_CRYNE Ras-like protein
Length = 216
Score = 159 bits (401), Expect = 1e-38
Identities = 81/154 (52%), Positives = 108/154 (70%)
Frame = +3
Query: 108 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFAAMRESYYRTA 287
KSA+ +QF+Q FV+ +DPTIE +Y K +D E + L+V DTAGQEE+ AMRE Y RT
Sbjct: 22 KSALTIQFIQSHFVDEYDPTIEDSYRKQCIIDEEVALLDVLDTAGQEEYGAMREQYMRTG 81
Query: 288 NGFLIVFSLTTRESFDMVRRFHKSALRSRDRDHFPMLLVANKTDLESSRKVSPSEIEDLA 467
GFL+V+S+T+R SF+ V FH+ LR +D+D+FP+++VANK DLE R+V P E DLA
Sbjct: 82 EGFLLVYSITSRSSFEEVSTFHQQILRVKDKDYFPVVVVANKCDLEYERQVQPHEGRDLA 141
Query: 468 KELQIDYTETSAKNPPVNIDDAFSQIVRKIRSHQ 569
K ETSAK VN+D+AF +VR IR +Q
Sbjct: 142 KRFNAQCIETSAKQ-RVNVDEAFIAVVRAIRRYQ 174
>sp|P04388|RAS2_DROME Ras-like protein 2
Length = 192
Score = 158 bits (400), Expect = 2e-38
Identities = 81/176 (46%), Positives = 116/176 (65%), Gaps = 2/176 (1%)
Frame = +3
Query: 108 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFAAMRESYYRTA 287
KSAI +QF+Q FV ++DPTIE +Y K +D + L++ DTAGQEEF+AMRE Y R+
Sbjct: 18 KSAITIQFIQSYFVTDYDPTIEDSYTKQCNIDDVPAKLDILDTAGQEEFSAMREQYMRSG 77
Query: 288 NGFLIVFSLTTRESFDMVRRFHKSALRSRDRDHFPMLLVANKTDLESSRKVSPSEIEDLA 467
GFL+VF+L SFD + +F + LR +DRD FPML+V NK DL+ ++VS E ++ +
Sbjct: 78 EGFLLVFALNDHSSFDEIPKFQRQILRVKDRDEFPMLMVGNKCDLKHQQQVSLEEAQNTS 137
Query: 468 KELQIDYTETSAKNPPVNIDDAFSQIVRKIRSHQLIND--VKTKSRPRQKQKCCLM 629
+ L I Y E SAK VN+D AF ++VR +R Q+ ++ + + K+KCCLM
Sbjct: 138 RNLMIPYIECSAK-LRVNVDQAFHELVRIVRKFQIAERPFIEQDYKKKGKRKCCLM 192
>sp|P08647|RAS_SCHPO Ras-like protein 1
Length = 219
Score = 156 bits (395), Expect = 6e-38
Identities = 79/153 (51%), Positives = 111/153 (72%)
Frame = +3
Query: 108 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFAAMRESYYRTA 287
KSA+ +Q +Q FV+ +DPTIE +Y K E+DGE + L+V DTAGQEE++AMRE Y RT
Sbjct: 21 KSALTIQLIQSHFVDEYDPTIEDSYRKKCEIDGEGALLDVLDTAGQEEYSAMREQYMRTG 80
Query: 288 NGFLIVFSLTTRESFDMVRRFHKSALRSRDRDHFPMLLVANKTDLESSRKVSPSEIEDLA 467
GFL+V+++T+R SFD + F++ LR +D+D FP++LVANK DLE+ R VS +E E LA
Sbjct: 81 EGFLLVYNITSRSSFDEISTFYQQILRVKDKDTFPVVLVANKCDLEAERVVSRAEGEQLA 140
Query: 468 KELQIDYTETSAKNPPVNIDDAFSQIVRKIRSH 566
K + Y ETSAK +N+++AF +VR IR +
Sbjct: 141 KSMHCLYVETSAK-LRLNVEEAFYSLVRTIRRY 172
>sp|P62070|RRAS2_HUMAN Ras-related protein R-Ras2 (Ras-like protein TC21) (Teratocarcinoma
oncogene)
sp|P62071|RRAS2_MOUSE Ras-related protein R-Ras2
Length = 204
Score = 156 bits (394), Expect = 8e-38
Identities = 82/189 (43%), Positives = 117/189 (61%)
Frame = +3
Query: 51 DLSNMAKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQ 230
D S K + KSA+ +QF+Q FV ++DPTIE +Y K +D + L++
Sbjct: 8 DGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDIL 67
Query: 231 DTAGQEEFAAMRESYYRTANGFLIVFSLTTRESFDMVRRFHKSALRSRDRDHFPMLLVAN 410
DTAGQEEF AMRE Y RT GFL+VFS+T R SF+ + +F + LR +DRD FPM+L+ N
Sbjct: 68 DTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGN 127
Query: 411 KTDLESSRKVSPSEIEDLAKELQIDYTETSAKNPPVNIDDAFSQIVRKIRSHQLINDVKT 590
K DL+ R+V+ E + LA++L++ Y E SAK +N+D AF ++VR IR Q +
Sbjct: 128 KADLDHQRQVTQEEGQQLARQLKVTYMEASAK-IRMNVDQAFHELVRVIRKFQ-EQECPP 185
Query: 591 KSRPRQKQK 617
P +K+K
Sbjct: 186 SPEPTRKEK 194
>sp|Q05058|RASL_COPCI 24 kDa RAS-like protein
Length = 215
Score = 156 bits (394), Expect = 8e-38
Identities = 78/153 (50%), Positives = 109/153 (71%)
Frame = +3
Query: 108 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFAAMRESYYRTA 287
KSA+ +QF+Q FV+ +DPTIE +Y K +D E + L+V DTAGQEE+ AMRE Y RT
Sbjct: 23 KSALTIQFIQSHFVDEYDPTIEDSYRKQCIIDDEVALLDVLDTAGQEEYGAMREQYMRTG 82
Query: 288 NGFLIVFSLTTRESFDMVRRFHKSALRSRDRDHFPMLLVANKTDLESSRKVSPSEIEDLA 467
GFL+V+S+T+R SF+ + FH+ LR +D+D FP+++VANK DLE R+V +E DLA
Sbjct: 83 EGFLLVYSITSRNSFEEISIFHQQILRVKDQDSFPVIVVANKCDLEYERQVGMNEGRDLA 142
Query: 468 KELQIDYTETSAKNPPVNIDDAFSQIVRKIRSH 566
K + ETSAK +N+D+AFS +VR+IR +
Sbjct: 143 KHFGCKFIETSAKQ-RINVDEAFSNLVREIRKY 174
>sp|P22278|RAS1_RHIRA Ras-like protein 1
Length = 203
Score = 155 bits (392), Expect = 1e-37
Identities = 80/181 (44%), Positives = 115/181 (63%), Gaps = 7/181 (3%)
Frame = +3
Query: 108 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFAAMRESYYRTA 287
KSA+ +QF+Q FV+ +DPTIE +Y K +D E + L+V DTAGQEE++AMRE Y R
Sbjct: 23 KSALTIQFIQSHFVDEYDPTIEDSYRKQCVIDSETALLDVLDTAGQEEYSAMREQYMRNG 82
Query: 288 NGFLIVFSLTTRESFDMVRRFHKSALRSRDRDHFPMLLVANKTDLESSRKVSPSEIEDLA 467
GFL+V+S+T+R SF+ + F++ R +DRD+FPM+LV NK DLE R+VS E DLA
Sbjct: 83 EGFLLVYSITSRLSFEEITTFYQQICRVKDRDYFPMVLVGNKCDLEGDRQVSSQEGRDLA 142
Query: 468 KELQIDYTETSAKNPPVNIDDAFSQIVRKIRSHQLINDVKTKSR-------PRQKQKCCL 626
K + ETSAK +N+D+AF ++VR IR + + + + KCC+
Sbjct: 143 KNFGCQFIETSAKQ-RINVDEAFFEVVRDIRRYNKEQETRGHDQFGIQDAPDVASDKCCI 201
Query: 627 M 629
+
Sbjct: 202 L 202
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 96,394,103
Number of Sequences: 369166
Number of extensions: 1914524
Number of successful extensions: 5280
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4941
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5055
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8390082510
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)